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27-01-2021 | Article

Psychopharmacological Treatments in Children with Fetal Alcohol Spectrum Disorders: A Review

Auteurs: Gaby J. Ritfeld, Julie A. Kable, Jennifer E. Holton, Claire D. Coles

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 2/2022

Abstract

Psychiatric symptoms in children with Fetal Alcohol Spectrum Disorders (FASD) present with high prevalence and morbidity, often across symptom domains, e.g. ADHD-like symptoms, emotional dysregulation and sleep problems. Polypharmacy is often used, but no empirically-based guidelines exist regarding optimal treatment for these children. Moreover, stimulant use in these children is controversial as their responsiveness may be different due to altered neural circuitry associated with prenatal alcohol exposure. The objective of this review is to give an overview of existing data on pharmacological treatments of neurobehavioral symptoms in FASD. Our literature review yielded limited and conflicting clinical data on the effectiveness of pharmacological treatments for psychiatric symptoms in children with FASD, with some symptom domains lacking data altogether. We emphasize the need for clinical trials to guide pharmacological treatments in this complex population.

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Titel: Psychopharmacological Treatments in Children with Fetal Alcohol Spectrum Disorders: A Review
Auteurs: Gaby J. Ritfeld
Julie A. Kable
Jennifer E. Holton
Claire D. Coles
Publicatiedatum: 27-01-2021
Uitgeverij: Springer US
Gepubliceerd in: Child Psychiatry & Human Development / Uitgave 2/2022
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI: https://doi.org/10.1007/s10578-021-01124-7

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