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11-07-2015 | Brief Communication

How does the EQ-5D perform when measuring quality of life in dementia against two other dementia-specific outcome measures?

Auteurs: Elisa Aguirre, Sujin Kang, Zoe Hoare, Rhiannon Tudor Edwards, Martin Orrell

Gepubliceerd in: Quality of Life Research | Uitgave 1/2016

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Abstract

Purpose

This study aimed to assess and compare the psychometric performance of the EQ-5D in relation to other dementia-specific measures, the QoL-AD and DEMQoL, within a psychosocial intervention study.

Methods

Two hundred and seventy-two people with dementia completed the EQ-5D, DEMQoL and QoL-AD. Convergent and discriminant validity of the measures were assessed, and inter-rater reliability was tested by comparing the self-reported and proxy scores of the measures. Internal consistency was tested using Cronbach’s alpha.

Results

Results satisfy convergent validity amongst the three outcome measures. EQ-5D, DEMQoL and QoL-AD total scores were shown to be significantly correlated with each other (p < 0.001) in both participants with dementia and proxy reports. Results also satisfied discriminant validity for participant EQ-5D, DEMQoL and QoL-AD total scores. In relation to reliability between self and proxy scores, the EQ-5D showed higher reliability scores between participant and proxy total scores for mild and moderate level of cognitive impairment and performed better than the dementia-specific measures. Reliability assessed through Cronbach’s alpha was satisfactory, indicating adequate internal consistency of all three measures.

Conclusions

The results suggest that the EQ-5D might have advantages over other dementia-specific measures, and it could be used routinely and as a stand-alone measure of quality of life in dementia research.
Literatuur
1.
go back to reference Woods, R. T., Bruce, E., Edwards, R. T., Hounsome, B., Keady, J., Moniz-Cook, E. D., et al. (2009). Reminiscence groups for people with dementia and their family carers: Pragmatic eight-centre randomised trial of joint reminiscence and maintenance versus usual treatment: A protocol. Trials, 10(1), 64.PubMedPubMedCentralCrossRef Woods, R. T., Bruce, E., Edwards, R. T., Hounsome, B., Keady, J., Moniz-Cook, E. D., et al. (2009). Reminiscence groups for people with dementia and their family carers: Pragmatic eight-centre randomised trial of joint reminiscence and maintenance versus usual treatment: A protocol. Trials, 10(1), 64.PubMedPubMedCentralCrossRef
2.
go back to reference Aguirre, E., Spector, A., Hoe, J., Russell, I. T., Knapp, M., Woods, R. T., & Orrell, M. (2010). Maintenance cognitive stimulation therapy (CST) for dementia: A single-blind, multi-centre, randomized controlled trial of maintenance CST vs. CST for dementia. Trials, 11(1), 46.PubMedPubMedCentralCrossRef Aguirre, E., Spector, A., Hoe, J., Russell, I. T., Knapp, M., Woods, R. T., & Orrell, M. (2010). Maintenance cognitive stimulation therapy (CST) for dementia: A single-blind, multi-centre, randomized controlled trial of maintenance CST vs. CST for dementia. Trials, 11(1), 46.PubMedPubMedCentralCrossRef
3.
go back to reference Charlesworth, G., Burnell, K., Beecham, J., Hoare, Z., Hoe, J., Wenborn, J., et al. (2011). Peer support for family carers of people with dementia, alone or in combination with group reminiscence in a factorial design: Study protocol for a randomised controlled trial. Trials, 12(205). doi:10.1186/1745-6215-12-205. Charlesworth, G., Burnell, K., Beecham, J., Hoare, Z., Hoe, J., Wenborn, J., et al. (2011). Peer support for family carers of people with dementia, alone or in combination with group reminiscence in a factorial design: Study protocol for a randomised controlled trial. Trials, 12(205). doi:10.​1186/​1745-6215-12-205.
4.
go back to reference Orrell, M., Yates, L. A., Burns, A., Russell, I., Woods, R. T., Hoare, Z., et al. (2012). Individual cognitive stimulation therapy for dementia (iCST): Study protocol for a randomized controlled trial. Trials, 13(1), 172.PubMedPubMedCentralCrossRef Orrell, M., Yates, L. A., Burns, A., Russell, I., Woods, R. T., Hoare, Z., et al. (2012). Individual cognitive stimulation therapy for dementia (iCST): Study protocol for a randomized controlled trial. Trials, 13(1), 172.PubMedPubMedCentralCrossRef
5.
go back to reference Ettema, T. P., Dröes, R. M., Lange, J. D., Mellenbergh, G. J., & Ribbe, M. W. (2005). A review of quality of life instruments used in dementia. Quality of Life Research, 14(3), 675–686.PubMedCrossRef Ettema, T. P., Dröes, R. M., Lange, J. D., Mellenbergh, G. J., & Ribbe, M. W. (2005). A review of quality of life instruments used in dementia. Quality of Life Research, 14(3), 675–686.PubMedCrossRef
6.
go back to reference Ettema, T. P., Dröes, R. M., de Lange, J., Ooms, M. E., Mellenbergh, G. J., & Ribbe, M. W. (2005). The concept of quality of life in dementia in the different stages of the disease. International Psychogeriatrics, 17(03), 353–370.PubMedCrossRef Ettema, T. P., Dröes, R. M., de Lange, J., Ooms, M. E., Mellenbergh, G. J., & Ribbe, M. W. (2005). The concept of quality of life in dementia in the different stages of the disease. International Psychogeriatrics, 17(03), 353–370.PubMedCrossRef
7.
go back to reference Ready, R. E., Ott, B. R., & Grace, J. (2004). Patient versus informant perspectives of quality of life in mild cognitive impairment and Alzheimer’s disease. International Journal of Geriatric Psychiatry, 19(3), 256–265.PubMedCrossRef Ready, R. E., Ott, B. R., & Grace, J. (2004). Patient versus informant perspectives of quality of life in mild cognitive impairment and Alzheimer’s disease. International Journal of Geriatric Psychiatry, 19(3), 256–265.PubMedCrossRef
8.
go back to reference Moniz-Cook, E., Vernooij-Dassen, M., Woods, R., et al. (2008). A European consensus on outcome measures for psychosocial intervention research in dementia care. Aging and Mental Health, 12, 14–25.PubMedCrossRef Moniz-Cook, E., Vernooij-Dassen, M., Woods, R., et al. (2008). A European consensus on outcome measures for psychosocial intervention research in dementia care. Aging and Mental Health, 12, 14–25.PubMedCrossRef
9.
go back to reference Sullivan, P. W., Slejko, J. F., Sculpher, M. J., & Ghushchyan, V. (2011). Catalogue of EQ-5D scores for the United Kingdom. Medical Decision Making, 31(6), 800–804.PubMedCrossRef Sullivan, P. W., Slejko, J. F., Sculpher, M. J., & Ghushchyan, V. (2011). Catalogue of EQ-5D scores for the United Kingdom. Medical Decision Making, 31(6), 800–804.PubMedCrossRef
10.
go back to reference The EuroQol Group. (1990). EuroQol—a new facility for the measurement of health related quality of life. Health Policy, 16, 199–208. The EuroQol Group. (1990). EuroQol—a new facility for the measurement of health related quality of life. Health Policy, 16, 199–208.
11.
go back to reference Kunz, S. (2010). Psychometric properties of the EQ-5D in a study of people with mild to moderate dementia. Quality of Life Research, 19(3), 425–434.PubMedCrossRef Kunz, S. (2010). Psychometric properties of the EQ-5D in a study of people with mild to moderate dementia. Quality of Life Research, 19(3), 425–434.PubMedCrossRef
12.
go back to reference Aggarwal, R., Wilke, C. T., Pickard, A. S., Vats, V., Mikolaitis, R., Fogg, L., et al. (2009). Psychometric properties of the EuroQol-5D and Short Form-6D in patients with systemic lupus erythematosus. Journal of Rheumatology, 36(6), 1209–1216.PubMedCrossRef Aggarwal, R., Wilke, C. T., Pickard, A. S., Vats, V., Mikolaitis, R., Fogg, L., et al. (2009). Psychometric properties of the EuroQol-5D and Short Form-6D in patients with systemic lupus erythematosus. Journal of Rheumatology, 36(6), 1209–1216.PubMedCrossRef
13.
go back to reference Öster, C., Willebrand, M., Dyster-Aas, J., Kildal, M., & Ekselius, L. (2005). Validation of the EQ-5D questionnaire in burn injured adults. Burns, 35(5), 723–732.CrossRef Öster, C., Willebrand, M., Dyster-Aas, J., Kildal, M., & Ekselius, L. (2005). Validation of the EQ-5D questionnaire in burn injured adults. Burns, 35(5), 723–732.CrossRef
14.
go back to reference Zhao, F. L., Yue, M., Yang, H., Wang, T., Wu, J. H., & Li, S. C. (2010). Validation and comparison of EuroQol and short form 6D in chronic prostatitis patients. Value in Health, 13(5), 649–656.PubMedCrossRef Zhao, F. L., Yue, M., Yang, H., Wang, T., Wu, J. H., & Li, S. C. (2010). Validation and comparison of EuroQol and short form 6D in chronic prostatitis patients. Value in Health, 13(5), 649–656.PubMedCrossRef
15.
go back to reference Diaz-Redondo, A., Rodriguez-Blazquez, C., Ayala, A., Martinez-Martin, P., & Forjaz, M. J. (2014). EQ-5D rated by proxy in institutionalized older adults with dementia: Psychometric pros and cons. Geriatrics & Gerontology International, 14(2), 346–353.CrossRef Diaz-Redondo, A., Rodriguez-Blazquez, C., Ayala, A., Martinez-Martin, P., & Forjaz, M. J. (2014). EQ-5D rated by proxy in institutionalized older adults with dementia: Psychometric pros and cons. Geriatrics & Gerontology International, 14(2), 346–353.CrossRef
16.
go back to reference Hounsome, N., Orrell, M., & Tudor Edwards, R. (2011). EQ-5D as a quality of life measure in people with dementia and their carers: Evidence and key issues. Value in Health, 14(2), 390–399.PubMedCrossRef Hounsome, N., Orrell, M., & Tudor Edwards, R. (2011). EQ-5D as a quality of life measure in people with dementia and their carers: Evidence and key issues. Value in Health, 14(2), 390–399.PubMedCrossRef
17.
go back to reference Ankri, J., Beaufils, B., Novella, J. L., Morrone, I., Guillemin, F., Jolly, D., et al. (2003). Use of the EQ-5D among patients suffering from dementia. Journal of Clinical Epidemiology, 56(11), 1055–1063.PubMedCrossRef Ankri, J., Beaufils, B., Novella, J. L., Morrone, I., Guillemin, F., Jolly, D., et al. (2003). Use of the EQ-5D among patients suffering from dementia. Journal of Clinical Epidemiology, 56(11), 1055–1063.PubMedCrossRef
18.
go back to reference Logsdon, R. G., Gibbons, L. E., McCurry, S. M., & Teri, L. (1999). Quality of life in Alzheimer’s disease: Patient and caregiver reports. Journal of Mental Health and Aging, 64(3), 510–519. Logsdon, R. G., Gibbons, L. E., McCurry, S. M., & Teri, L. (1999). Quality of life in Alzheimer’s disease: Patient and caregiver reports. Journal of Mental Health and Aging, 64(3), 510–519.
19.
go back to reference Spector, A., Thorgrimsen, L., Woods, B. O. B., Royan, L., Davies, S., Butterworth, M., & Orrell, M. (2003). Efficacy of an evidence-based cognitive stimulation therapy programme for people with dementia Randomised controlled trial. British Journal of Psychiatry, 183(3), 248–254.PubMedCrossRef Spector, A., Thorgrimsen, L., Woods, B. O. B., Royan, L., Davies, S., Butterworth, M., & Orrell, M. (2003). Efficacy of an evidence-based cognitive stimulation therapy programme for people with dementia Randomised controlled trial. British Journal of Psychiatry, 183(3), 248–254.PubMedCrossRef
20.
go back to reference Orrell, M., Aguirre, E., Spector, A., Hoare, Z., Streater, A., Woods, B., et al. (2014). Maintenance cognitive stimulation therapy (CST) for dementia: A single-blind, multi-centre, randomized controlled trial of maintenance CST vs. CST for dementia. BMJ, 204(6), 454–461. Orrell, M., Aguirre, E., Spector, A., Hoare, Z., Streater, A., Woods, B., et al. (2014). Maintenance cognitive stimulation therapy (CST) for dementia: A single-blind, multi-centre, randomized controlled trial of maintenance CST vs. CST for dementia. BMJ, 204(6), 454–461.
21.
go back to reference Hoe, J., Hancock, G., Livingston, G., & Orrell, M. (2006). Quality of life of people with dementia in residential care homes. British Journal of Psychiatry, 188(5), 460–464.PubMedCrossRef Hoe, J., Hancock, G., Livingston, G., & Orrell, M. (2006). Quality of life of people with dementia in residential care homes. British Journal of Psychiatry, 188(5), 460–464.PubMedCrossRef
22.
go back to reference Thorgrimsen, L., Selwood, A., Spector, A., et al. (2003). Whose quality of life is it anyway? The validity and reliability of the quality of life-Alzheimer’s disease (QoL-AD) scale. Alzheimer Disease and Associated Disorders, 17, 201–208.PubMedCrossRef Thorgrimsen, L., Selwood, A., Spector, A., et al. (2003). Whose quality of life is it anyway? The validity and reliability of the quality of life-Alzheimer’s disease (QoL-AD) scale. Alzheimer Disease and Associated Disorders, 17, 201–208.PubMedCrossRef
23.
go back to reference Smith, S. C., Lamping, D. L., Banerjee, S., Harwood, R., Foley, B., Smith, P., et al. (2005). Measurement of health-related quality of life for people with dementia: Development of a new instrument (DEMQoL) and an evaluation of current methodology. Health Technology, (Winchester, England), 9(10), 1–93. Smith, S. C., Lamping, D. L., Banerjee, S., Harwood, R., Foley, B., Smith, P., et al. (2005). Measurement of health-related quality of life for people with dementia: Development of a new instrument (DEMQoL) and an evaluation of current methodology. Health Technology, (Winchester, England), 9(10), 1–93.
24.
go back to reference Mulhern, B., Rowen, D., Brazier, J., Smith, S., Romeo, R., Tait, R., et al. (2013). Development of DEMQOL-U and DEMQOL-Proxy-U: Generation of preference-based indices from DEMQOL and DEMQOL-Proxy for use in economic evaluation. Health Technology Assessment, 17, 1–160.CrossRef Mulhern, B., Rowen, D., Brazier, J., Smith, S., Romeo, R., Tait, R., et al. (2013). Development of DEMQOL-U and DEMQOL-Proxy-U: Generation of preference-based indices from DEMQOL and DEMQOL-Proxy for use in economic evaluation. Health Technology Assessment, 17, 1–160.CrossRef
25.
go back to reference American Psychiatric Association, & American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (DSM) (pp. 143–147). Washington, DC: American psychiatric association. American Psychiatric Association, & American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (DSM) (pp. 143–147). Washington, DC: American psychiatric association.
26.
go back to reference Hughes, C. P., Berg, L., Danziger, W. L., Coben, L. A., & Martin, R. L. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140(6), 566–572.PubMedCrossRef Hughes, C. P., Berg, L., Danziger, W. L., Coben, L. A., & Martin, R. L. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140(6), 566–572.PubMedCrossRef
27.
go back to reference Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). ‘Mini Mental State’: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.PubMedCrossRef Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). ‘Mini Mental State’: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.PubMedCrossRef
28.
go back to reference Tombaugh, T. N., & McIntyre, N. J. (1992). The mini-mental state examination: A comprehensive review. Journal of the American Geriatrics Society, 40(9), 922–935.PubMedCrossRef Tombaugh, T. N., & McIntyre, N. J. (1992). The mini-mental state examination: A comprehensive review. Journal of the American Geriatrics Society, 40(9), 922–935.PubMedCrossRef
29.
go back to reference Cohen, J. (1988). Statistical power analysis for the behavioural sciences (2nd ed.). Hillsdale, NJ: Lawrence Erlbaum Publishers. Cohen, J. (1988). Statistical power analysis for the behavioural sciences (2nd ed.). Hillsdale, NJ: Lawrence Erlbaum Publishers.
30.
go back to reference Nunnally, J. C., & Bernstein, I. H. (1994). Psychometric theory (3rd ed.). New York, NY: McCraw-Hill. Nunnally, J. C., & Bernstein, I. H. (1994). Psychometric theory (3rd ed.). New York, NY: McCraw-Hill.
31.
go back to reference Ratcliffe, J., Laver, K., Couzner, L., Cameron, I. D., Gray, L., & Crotty, M. (2010). Not just about costs: The role of health economics in facilitating decision making in aged care. Age and Ageing, 39(4), 426–429.PubMedCrossRef Ratcliffe, J., Laver, K., Couzner, L., Cameron, I. D., Gray, L., & Crotty, M. (2010). Not just about costs: The role of health economics in facilitating decision making in aged care. Age and Ageing, 39(4), 426–429.PubMedCrossRef
32.
go back to reference Bryan, S., Hardyman, W., Bentham, P., Buckley, A., & Laight, A. (2005). Proxy completion of EQ-5D in patients with dementia. Quality of Life Research, 14(1), 107–118.PubMedCrossRef Bryan, S., Hardyman, W., Bentham, P., Buckley, A., & Laight, A. (2005). Proxy completion of EQ-5D in patients with dementia. Quality of Life Research, 14(1), 107–118.PubMedCrossRef
33.
go back to reference Sheehan, B. D., Lall, R., Stinton, C., Mitchell, K., Gage, H., Holland, C., & Katz, J. (2012). Patient and proxy measurement of quality of life among general hospital in-patients with dementia. Aging & Mental Health, 16(5), 603–607.CrossRef Sheehan, B. D., Lall, R., Stinton, C., Mitchell, K., Gage, H., Holland, C., & Katz, J. (2012). Patient and proxy measurement of quality of life among general hospital in-patients with dementia. Aging & Mental Health, 16(5), 603–607.CrossRef
34.
go back to reference Coucill, W., Bryan, S., Bentham, P., Buckley, A., & Laight, A. (2001). EQ-5D in patients with dementia an investigation of inter-rater agreement. Medical Care, 39(8), 760–771.PubMedCrossRef Coucill, W., Bryan, S., Bentham, P., Buckley, A., & Laight, A. (2001). EQ-5D in patients with dementia an investigation of inter-rater agreement. Medical Care, 39(8), 760–771.PubMedCrossRef
35.
go back to reference Reamy, A. M., Kim, K., Zarit, S. H., & Whitlatch, C. J. (2011). Understanding discrepancy in perceptions of values: Individuals with mild to moderate dementia and their family caregivers. The Gerontologist, 51(4), 473–483.PubMedPubMedCentralCrossRef Reamy, A. M., Kim, K., Zarit, S. H., & Whitlatch, C. J. (2011). Understanding discrepancy in perceptions of values: Individuals with mild to moderate dementia and their family caregivers. The Gerontologist, 51(4), 473–483.PubMedPubMedCentralCrossRef
36.
go back to reference Bullinger, M., Anderson, R., Cella, D., & Aaronson, N. (1993). Developing and evaluating cross-cultural instruments from minimum requirements to optimal models. Quality of Life Research, 2(6), 451–459.PubMedCrossRef Bullinger, M., Anderson, R., Cella, D., & Aaronson, N. (1993). Developing and evaluating cross-cultural instruments from minimum requirements to optimal models. Quality of Life Research, 2(6), 451–459.PubMedCrossRef
37.
38.
go back to reference Streiner, D. (2003). Starting at the beginning: An introduction to coefficient alpha and internal consistency. Journal of Personality Assessment, 80, 99–103.PubMedCrossRef Streiner, D. (2003). Starting at the beginning: An introduction to coefficient alpha and internal consistency. Journal of Personality Assessment, 80, 99–103.PubMedCrossRef
39.
go back to reference Ready, R. E. (2011). Measuring quality of life in dementia. Quality of Life Measurement in Neurodegenerative and Related Conditions, 8, 82–94.CrossRef Ready, R. E. (2011). Measuring quality of life in dementia. Quality of Life Measurement in Neurodegenerative and Related Conditions, 8, 82–94.CrossRef
Metagegevens
Titel
How does the EQ-5D perform when measuring quality of life in dementia against two other dementia-specific outcome measures?
Auteurs
Elisa Aguirre
Sujin Kang
Zoe Hoare
Rhiannon Tudor Edwards
Martin Orrell
Publicatiedatum
11-07-2015
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 1/2016
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-015-1065-9

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