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11-07-2015 | Brief Communication

How does the EQ-5D perform when measuring quality of life in dementia against two other dementia-specific outcome measures?

Auteurs: Elisa Aguirre, Sujin Kang, Zoe Hoare, Rhiannon Tudor Edwards, Martin Orrell

Gepubliceerd in: Quality of Life Research | Uitgave 1/2016

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Abstract

Purpose

This study aimed to assess and compare the psychometric performance of the EQ-5D in relation to other dementia-specific measures, the QoL-AD and DEMQoL, within a psychosocial intervention study.

Methods

Two hundred and seventy-two people with dementia completed the EQ-5D, DEMQoL and QoL-AD. Convergent and discriminant validity of the measures were assessed, and inter-rater reliability was tested by comparing the self-reported and proxy scores of the measures. Internal consistency was tested using Cronbach’s alpha.

Results

Results satisfy convergent validity amongst the three outcome measures. EQ-5D, DEMQoL and QoL-AD total scores were shown to be significantly correlated with each other (p < 0.001) in both participants with dementia and proxy reports. Results also satisfied discriminant validity for participant EQ-5D, DEMQoL and QoL-AD total scores. In relation to reliability between self and proxy scores, the EQ-5D showed higher reliability scores between participant and proxy total scores for mild and moderate level of cognitive impairment and performed better than the dementia-specific measures. Reliability assessed through Cronbach’s alpha was satisfactory, indicating adequate internal consistency of all three measures.

Conclusions

The results suggest that the EQ-5D might have advantages over other dementia-specific measures, and it could be used routinely and as a stand-alone measure of quality of life in dementia research.
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Metagegevens
Titel
How does the EQ-5D perform when measuring quality of life in dementia against two other dementia-specific outcome measures?
Auteurs
Elisa Aguirre
Sujin Kang
Zoe Hoare
Rhiannon Tudor Edwards
Martin Orrell
Publicatiedatum
11-07-2015
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 1/2016
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-015-1065-9