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Quality of Life Research
Gepubliceerd in: Quality of Life Research 4/2019

10-11-2018

Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study

Auteurs: Rodolfo Castro, Raquel B. De Boni, Paula M. Luz, Luciane Velasque, Livia V. Lopes, Antonieta Medina-Lara, Sandra W. Cardoso, Marilia S. De Oliveira, Ruth K. Friedman, Beatriz Grinsztejn, Valdiléa G. Veloso

Gepubliceerd in: Quality of Life Research | Uitgave 4/2019

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Abstract

Purpose

To assess health-related quality of life (HRQoL) and its associated factors among people living with HIV/AIDS (PLWHA) in Rio de Janeiro, Brazil.

Methods

A cross-sectional study including PLWHA receiving usual HIV-care at Instituto Nacional de Infectologia Evandro Chagas (INI/Fiocruz) was conducted between 2014 and 2016 in Rio de Janeiro, Brazil. The EQ-5D-3L assessed HRQoL; PHQ-2 and ASSIST were used for screening depression and substance use, respectively. Clinical variables were obtained from the INI/Fiocruz cohort database, and structured questions evaluated intimate partner violence, sexual abstinence and relationship status. Data were analysed using multivariable Tobit regression model.

Results

A total of 1480 PLWHA were included: 64.7% were male at birth (38.4% men who have sex with men [MSM], 24.3% heterosexual men and 2% transgender women [TGW]); median age was 43.1 years, and 95.8% were receiving antiretroviral therapy. The median EQ-5D-3L utility score was 0.801. Results showed that the following factors: MSM and women; older age; lower educational level; no engagement in a relationship; depression screening positive; polysubstance use; and, detectable viral load were independently associated with worse HRQoL.

Conclusions

PLWHA under care at INI/Fiocruz presented good HRQoL. Polysubstance use, depression and lower educational level were among the factors negatively associated with HRQoL. This was the first time that the EQ-5D-3L utility scores were calculated for a considerable number of PLWHA in Brazil, which is a fundamental piece of information for future cost-effectiveness analysis.
vorige artikel Assessing test–retest reliability of patient-reported outcome measures using intraclass correlation coefficients: recommendations for selecting and documenting the analytical formula
volgende artikel Pain, skin sensations symptoms, and cognitive functioning predictors of health-related quality of life in pediatric patients with Neurofibromatosis Type 1
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Metagegevens
Titel
Health-related quality of life assessment among people living with HIV in Rio de Janeiro, Brazil: a cross-sectional study
Auteurs
Rodolfo Castro
Raquel B. De Boni
Paula M. Luz
Luciane Velasque
Livia V. Lopes
Antonieta Medina-Lara
Sandra W. Cardoso
Marilia S. De Oliveira
Ruth K. Friedman
Beatriz Grinsztejn
Valdiléa G. Veloso
Publicatiedatum
10-11-2018
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 4/2019
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-018-2044-8

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