Skip to main content
Top
Gepubliceerd in:

18-12-2018 | Review

Health-related quality of life among adults living with diabetic foot ulcers: a meta-analysis

Auteurs: Saneh Khunkaew, Ritin Fernandez, Jenny Sim

Gepubliceerd in: Quality of Life Research | Uitgave 6/2019

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Purpose

To undertake a systematic review of the literature to investigate the HRQOL among adults living with DFUs.

Methods

A systematic search of the medical and nursing/health content databases including MEDLINE, CINAHL, and PsycINFO was conducted up to November 2018. The methodological quality of each study was assessed independently by all authors using the Joanna Briggs Institute checklist. Data analysis was conducted using the Comprehensive Meta-analysis software. All analyses were performed using random-effects models and heterogeneity was quantified.

Results

A total of 12 studies were included in the review. Overall, the HRQOL of participants in the studies was poor on four of eight subscales in the SF-36: physical functioning (mean = 42.75, SE 1.5); role physical (mean = 20.61, SE 3.4); general health (mean = 39.52, SE 1.7); and vitality (mean = 45.73, SE 2.8). In addition, presence of pain, high levels of C-reactive protein (> 10 mg/L), ulcer size > 5 cm2, Ankle Brachial Index < 0.9, high glycosylated haemoglobin and body mass index > 25 kg/m2 were associated with poorer HRQOL in people with DFUs.

Conclusions

This review has provided evidence indicating that people with DFUs have a significantly lower HRQOL. Evidence-based interventions to improve the HRQOL in this group of people is needed.
Literatuur
5.
go back to reference Bradbury, S. E., & Price, P. E. (2011). Diabetic foot ulcer pain: the hidden burden (part one). EWMA Journal, 11(1), 11–22. Bradbury, S. E., & Price, P. E. (2011). Diabetic foot ulcer pain: the hidden burden (part one). EWMA Journal, 11(1), 11–22.
6.
go back to reference Sadosky, A., Schaefer, C., Mann, R., Bergstrom, F., Baik, R., Parsons, B., et al. (2013). Burden of illness associated with painful diabetic peripheral neuropathy among adults seeking treatment in the US: Results from a retrospective chart review and cross-sectional survey. Diabetes, Metabolic Syndrome And Obesity: Targets And Therapy, 6, 79–92. https://doi.org/10.2147/DMSO.S37415.CrossRef Sadosky, A., Schaefer, C., Mann, R., Bergstrom, F., Baik, R., Parsons, B., et al. (2013). Burden of illness associated with painful diabetic peripheral neuropathy among adults seeking treatment in the US: Results from a retrospective chart review and cross-sectional survey. Diabetes, Metabolic Syndrome And Obesity: Targets And Therapy, 6, 79–92. https://​doi.​org/​10.​2147/​DMSO.​S37415.CrossRef
7.
go back to reference Burant, C. F. (2008). Medical management of type 2 diabetes (Vol. Book, Whole). Alexandria: American Diabetes Association. Burant, C. F. (2008). Medical management of type 2 diabetes (Vol. Book, Whole). Alexandria: American Diabetes Association.
9.
go back to reference Carlos De Meneses, L., Blanes, L., Francescato Veiga, D., Gomes, H. C., & Ferreirai, L. M. (2011). Health-related quality of life and self-esteem in patients with diabetic foot ulcers: Results of a cross-sectional comparative study. Ostomy Wound Management, 57(3), 36–43. Carlos De Meneses, L., Blanes, L., Francescato Veiga, D., Gomes, H. C., & Ferreirai, L. M. (2011). Health-related quality of life and self-esteem in patients with diabetic foot ulcers: Results of a cross-sectional comparative study. Ostomy Wound Management, 57(3), 36–43.
10.
go back to reference Holland, C. M. (2012). Diabetic peripheral neuropathy: A barrier to quality of life. Communicating Nursing Research, 45, 405. Holland, C. M. (2012). Diabetic peripheral neuropathy: A barrier to quality of life. Communicating Nursing Research, 45, 405.
13.
14.
go back to reference Idler, E. L., & Benyamini, Y. (1997). Self-rated health and mortality: A review of twenty-seven community studies. Journal of Health and Social Behavior, 38(1), 21–37.CrossRef Idler, E. L., & Benyamini, Y. (1997). Self-rated health and mortality: A review of twenty-seven community studies. Journal of Health and Social Behavior, 38(1), 21–37.CrossRef
16.
go back to reference Garcia-Morales, E., Lazaro-Martinez, J. L., Martinez-Hernandez, D., Aragon-Sanchez, J., Beneit-Montesinos, J. V., & Gonzalez-Jurado, M. A. (2011). Impact of diabetic foot related complications on the Health Related Quality of Life (HRQol) of patients—A regional study in Spain. The International Journal of Lower Extremity Wounds, 10(1), 6–11. https://doi.org/10.1177/1534734611400257.CrossRefPubMed Garcia-Morales, E., Lazaro-Martinez, J. L., Martinez-Hernandez, D., Aragon-Sanchez, J., Beneit-Montesinos, J. V., & Gonzalez-Jurado, M. A. (2011). Impact of diabetic foot related complications on the Health Related Quality of Life (HRQol) of patients—A regional study in Spain. The International Journal of Lower Extremity Wounds, 10(1), 6–11. https://​doi.​org/​10.​1177/​1534734611400257​.CrossRefPubMed
17.
go back to reference Zoungas, S., Woodward, M., Li, Q., Cooper, M. E., Hamet, P., Harrap, S., et al. (2014). Impact of age, age at diagnosis and duration of diabetes on the risk of macrovascular and microvascular complications and death in type 2 diabetes. DIABETOLOGIA, 57(12), 2465–2474.CrossRefPubMed Zoungas, S., Woodward, M., Li, Q., Cooper, M. E., Hamet, P., Harrap, S., et al. (2014). Impact of age, age at diagnosis and duration of diabetes on the risk of macrovascular and microvascular complications and death in type 2 diabetes. DIABETOLOGIA, 57(12), 2465–2474.CrossRefPubMed
18.
go back to reference Al Hayek, A. A., Robert, A. A., Saeed, A., Alzaid, A., A. A., & Al Sabaan, F. S. (2014). Factors associated with health-related quality of life among Saudi patients with type 2 diabetes mellitus: A cross-sectional survey. Diabetes & Metabolism Journal, 38(3), 220–229.CrossRef Al Hayek, A. A., Robert, A. A., Saeed, A., Alzaid, A., A. A., & Al Sabaan, F. S. (2014). Factors associated with health-related quality of life among Saudi patients with type 2 diabetes mellitus: A cross-sectional survey. Diabetes & Metabolism Journal, 38(3), 220–229.CrossRef
19.
go back to reference Kim, E. S., Moon, S., Kim, H.-S., Lim, D. J., Cho, J. H., Kwon, H. S., et al. (2011). Diabetic peripheral neuropathy is associated with increased arterial stiffness without changes in carotid intima–media thickness in type 2 diabetes. Diabetes Care, 34(6), 1403–1405.CrossRefPubMedPubMedCentral Kim, E. S., Moon, S., Kim, H.-S., Lim, D. J., Cho, J. H., Kwon, H. S., et al. (2011). Diabetic peripheral neuropathy is associated with increased arterial stiffness without changes in carotid intima–media thickness in type 2 diabetes. Diabetes Care, 34(6), 1403–1405.CrossRefPubMedPubMedCentral
21.
go back to reference Yao, H., Ting, X., Minjie, W., Yemin, C., Xiqiao, W., Yuzhi, J., et al. (2012). The investigation of demographic characteristics and the health-related quality of life in patients with diabetic foot ulcers at first presentation. The International Journal of Lower Extremity Wounds, 11(3), 187–193. https://doi.org/10.1177/1534734612457034.CrossRefPubMed Yao, H., Ting, X., Minjie, W., Yemin, C., Xiqiao, W., Yuzhi, J., et al. (2012). The investigation of demographic characteristics and the health-related quality of life in patients with diabetic foot ulcers at first presentation. The International Journal of Lower Extremity Wounds, 11(3), 187–193. https://​doi.​org/​10.​1177/​1534734612457034​.CrossRefPubMed
25.
go back to reference Borenstein, M., Hedges, L., Higgins, J., & Rothstein, H. (2005). Comprehensive meta-analysis version 2 (p. 104). Englewood, NJ: Biostat. Borenstein, M., Hedges, L., Higgins, J., & Rothstein, H. (2005). Comprehensive meta-analysis version 2 (p. 104). Englewood, NJ: Biostat.
26.
go back to reference Hedges, L. V., & Olkin, I. (1985). Olkin. Statistical methods for meta-analysis. Orlando: Academic Press. Hedges, L. V., & Olkin, I. (1985). Olkin. Statistical methods for meta-analysis. Orlando: Academic Press.
27.
go back to reference Brockwell, S. E., & Gordon, I. R. (2001). A comparison of statistical methods for meta-analysis. Statistics in Medicine, 20(6), 825–840.CrossRefPubMed Brockwell, S. E., & Gordon, I. R. (2001). A comparison of statistical methods for meta-analysis. Statistics in Medicine, 20(6), 825–840.CrossRefPubMed
28.
go back to reference Kontopantelis, E., & Reeves, D. (2012). Performance of statistical methods for meta-analysis when true study effects are non-normally distributed: A simulation study. Statistical Methods in Medical Research, 21(4), 409–426.CrossRefPubMed Kontopantelis, E., & Reeves, D. (2012). Performance of statistical methods for meta-analysis when true study effects are non-normally distributed: A simulation study. Statistical Methods in Medical Research, 21(4), 409–426.CrossRefPubMed
29.
go back to reference Sterne, J. A., & Egger, M. (2001). Funnel plots for detecting bias in meta-analysis: Guidelines on choice of axis. Journal of Clinical Epidemiology, 54(10), 1046–1055.CrossRefPubMed Sterne, J. A., & Egger, M. (2001). Funnel plots for detecting bias in meta-analysis: Guidelines on choice of axis. Journal of Clinical Epidemiology, 54(10), 1046–1055.CrossRefPubMed
30.
go back to reference Lau, J., Ioannidis, J. P., & Schmid, C. H. (1998). Summing up evidence: One answer is not always enough. The Lancet, 351(9096), 123–127.CrossRef Lau, J., Ioannidis, J. P., & Schmid, C. H. (1998). Summing up evidence: One answer is not always enough. The Lancet, 351(9096), 123–127.CrossRef
31.
go back to reference Goodridge, D., Trepman, E., Sloan, J., Guse, L., Strain, L. A., McIntyre, J., et al. (2006). Quality of life of adults with unhealed and healed diabetic foot ulcers. Foot Ankle International, 27(4), 274–280.CrossRefPubMed Goodridge, D., Trepman, E., Sloan, J., Guse, L., Strain, L. A., McIntyre, J., et al. (2006). Quality of life of adults with unhealed and healed diabetic foot ulcers. Foot Ankle International, 27(4), 274–280.CrossRefPubMed
32.
go back to reference Siersma, V., Thorsen, H., Holstein, P. E., Kars, M., Apelqvist, J., Jude, E. B., et al. (2013). Importance of factors determining the low health-related quality of life in people presenting with a diabetic foot ulcer: The Eurodiale study. Diabetic Medicine, 30(11), 1382–1387. https://doi.org/10.1111/dme.12254.CrossRefPubMed Siersma, V., Thorsen, H., Holstein, P. E., Kars, M., Apelqvist, J., Jude, E. B., et al. (2013). Importance of factors determining the low health-related quality of life in people presenting with a diabetic foot ulcer: The Eurodiale study. Diabetic Medicine, 30(11), 1382–1387. https://​doi.​org/​10.​1111/​dme.​12254.CrossRefPubMed
33.
go back to reference Siersma, V., Thorsen, H., Holstein, P. E., Kars, M., Apelqvist, J., Jude, E. B., et al. (2017). Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers–the Eurodiale study. Journal of Diabetes and its Complications, 31(7), 1145–1151.CrossRefPubMed Siersma, V., Thorsen, H., Holstein, P. E., Kars, M., Apelqvist, J., Jude, E. B., et al. (2017). Diabetic complications do not hamper improvement of health-related quality of life over the course of treatment of diabetic foot ulcers–the Eurodiale study. Journal of Diabetes and its Complications, 31(7), 1145–1151.CrossRefPubMed
34.
go back to reference Winkley, K., Stahl, D., Chalder, T., Edmonds, M. E., & Ismail, K. (2009). Quality of life in people with their first diabetic foot ulcer: A prospective cohort study. Journal of the American Podiatric Medical Association, 99(5), 406–414.CrossRefPubMed Winkley, K., Stahl, D., Chalder, T., Edmonds, M. E., & Ismail, K. (2009). Quality of life in people with their first diabetic foot ulcer: A prospective cohort study. Journal of the American Podiatric Medical Association, 99(5), 406–414.CrossRefPubMed
35.
go back to reference Ribu, L., Rustøen, T., Birkeland, K., Hanestad, B. R., Paul, S. M., & Miaskowski, C. (2006). The prevalence and occurrence of diabetic foot ulcer pain and its impact on health-related quality of life. The Journal of Pain: Official Journal of The American Pain Society, 7(4), 290–299.CrossRef Ribu, L., Rustøen, T., Birkeland, K., Hanestad, B. R., Paul, S. M., & Miaskowski, C. (2006). The prevalence and occurrence of diabetic foot ulcer pain and its impact on health-related quality of life. The Journal of Pain: Official Journal of The American Pain Society, 7(4), 290–299.CrossRef
36.
go back to reference Valensi, P., Girod, I., Baron, F., Moreau-Defarges, T., & Guillon, P. (2005). Quality of life and clinical correlates in patients with diabetic foot ulcers. Diabetes & Metabolism, 31(3 Pt 1), 263–271.CrossRef Valensi, P., Girod, I., Baron, F., Moreau-Defarges, T., & Guillon, P. (2005). Quality of life and clinical correlates in patients with diabetic foot ulcers. Diabetes & Metabolism, 31(3 Pt 1), 263–271.CrossRef
39.
go back to reference Siersma, V., Thorsen, H., Holstein, P. E., Kars, M., Apelqvist, J., Jude, E. B., et al. (2014). Health-related quality of life predicts major amputation and death, but not healing, in people with diabetes presenting with foot ulcers: The Eurodiale study. Diabetes Care, 37(3), 694–700. https://doi.org/10.2337/dc13-1212.CrossRefPubMed Siersma, V., Thorsen, H., Holstein, P. E., Kars, M., Apelqvist, J., Jude, E. B., et al. (2014). Health-related quality of life predicts major amputation and death, but not healing, in people with diabetes presenting with foot ulcers: The Eurodiale study. Diabetes Care, 37(3), 694–700. https://​doi.​org/​10.​2337/​dc13-1212.CrossRefPubMed
41.
go back to reference Wagner, F. (1979). A classification and treatment program for diabetic, neuropathic, and dysvascular foot problems. Instructional Course Lectures, 28(1), 143–165. Wagner, F. (1979). A classification and treatment program for diabetic, neuropathic, and dysvascular foot problems. Instructional Course Lectures, 28(1), 143–165.
42.
go back to reference Lopes, C. R., Marcondes, F., Medeiros, Á., Larissa Marques Barreto Mello, S., & Valdeci Carlos, D. (2013). Evaluation of limitations of venous ulcers in legs. Jornal Vascular Brasileiro, 12(1), 5–9.CrossRef Lopes, C. R., Marcondes, F., Medeiros, Á., Larissa Marques Barreto Mello, S., & Valdeci Carlos, D. (2013). Evaluation of limitations of venous ulcers in legs. Jornal Vascular Brasileiro, 12(1), 5–9.CrossRef
43.
go back to reference Wachholz, P. A., Masuda, P. Y., Nascimento, D. C., Taira, C. M. H., & Cleto, N. G. (2014). Quality of life profile and correlated factors in chronic leg ulcer patients in the mid-west of São Paulo State, Brazil. Anais brasileiros de dermatologia, 89(1), 73–81.CrossRefPubMedPubMedCentral Wachholz, P. A., Masuda, P. Y., Nascimento, D. C., Taira, C. M. H., & Cleto, N. G. (2014). Quality of life profile and correlated factors in chronic leg ulcer patients in the mid-west of São Paulo State, Brazil. Anais brasileiros de dermatologia, 89(1), 73–81.CrossRefPubMedPubMedCentral
44.
go back to reference Hopman, W., Buchanan, M., VanDenKerkhof, E., & Harrison, M. (2013). Pain and health-related quality of life in people with chronic leg ulcers. Chronic Diseases and Injuries in Canada, 33(3), 167–174.PubMed Hopman, W., Buchanan, M., VanDenKerkhof, E., & Harrison, M. (2013). Pain and health-related quality of life in people with chronic leg ulcers. Chronic Diseases and Injuries in Canada, 33(3), 167–174.PubMed
45.
go back to reference Obilor, H., & Adejumo, P. O. (2015). Assessment of diabetic foot ulcer-related pain and its relationship to quality of life. Wound Practice & Research: Journal of the Australian Wound Management Association, 23(3), 124. Obilor, H., & Adejumo, P. O. (2015). Assessment of diabetic foot ulcer-related pain and its relationship to quality of life. Wound Practice & Research: Journal of the Australian Wound Management Association, 23(3), 124.
46.
go back to reference Gonzalez-Consuegra, R. V., & Verdu, J. (2011). Quality of life in people with venous leg ulcers: an integrative review. Journal of Advanced Nursing, 67(5), 926–944.CrossRefPubMed Gonzalez-Consuegra, R. V., & Verdu, J. (2011). Quality of life in people with venous leg ulcers: an integrative review. Journal of Advanced Nursing, 67(5), 926–944.CrossRefPubMed
47.
go back to reference Martin, C. L., Albers, J. W., Pop-Busui, R., & Group, D. E. r (2014). Neuropathy and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study. Diabetes Care, 37(1), 31–38.CrossRefPubMed Martin, C. L., Albers, J. W., Pop-Busui, R., & Group, D. E. r (2014). Neuropathy and related findings in the diabetes control and complications trial/epidemiology of diabetes interventions and complications study. Diabetes Care, 37(1), 31–38.CrossRefPubMed
49.
go back to reference Khunkaew, S., Tungpunkom, P., Sim, J., & Fernandez, R. (2018). The experiences of people in Northern Thailand living with diabetic foot ulcers: A descriptive qualitative study. Pacific Rim Internation Journal Nursing Research, 22(4), 304–318. Khunkaew, S., Tungpunkom, P., Sim, J., & Fernandez, R. (2018). The experiences of people in Northern Thailand living with diabetic foot ulcers: A descriptive qualitative study. Pacific Rim Internation Journal Nursing Research, 22(4), 304–318.
50.
go back to reference Peker, A., & Karaöz, S. (2017). The effects of social support and hope in the healing of diabetic foot ulcers treated with standard care. Population Health Management, 20(6), 507–507.CrossRefPubMed Peker, A., & Karaöz, S. (2017). The effects of social support and hope in the healing of diabetic foot ulcers treated with standard care. Population Health Management, 20(6), 507–507.CrossRefPubMed
52.
go back to reference Swardfager, W., Yang, P., Herrmann, N., Lanctôt, K. L., Shah, B. R., Kiss, A., et al. (2016). Depressive symptoms predict non-completion of a structured exercise intervention for people with Type 2 diabetes. Diabetic Medicine: A Journal of the British Diabetic Association, 33(4), 529–536. https://doi.org/10.1111/dme.12872.CrossRef Swardfager, W., Yang, P., Herrmann, N., Lanctôt, K. L., Shah, B. R., Kiss, A., et al. (2016). Depressive symptoms predict non-completion of a structured exercise intervention for people with Type 2 diabetes. Diabetic Medicine: A Journal of the British Diabetic Association, 33(4), 529–536. https://​doi.​org/​10.​1111/​dme.​12872.CrossRef
53.
go back to reference Tušek-Bunc, K., & Petek, D. (2016). Comorbidities and characteristics of coronary heart disease patients: Their impact on health-related quality of life. Health and Quality of Life Outcomes, 14(1), 159–159.CrossRefPubMedPubMedCentral Tušek-Bunc, K., & Petek, D. (2016). Comorbidities and characteristics of coronary heart disease patients: Their impact on health-related quality of life. Health and Quality of Life Outcomes, 14(1), 159–159.CrossRefPubMedPubMedCentral
54.
go back to reference Heisler, M. (2009). Different models to mobilize peer support to improve diabetes self-management and clinical outcomes: Evidence, logistics, evaluation considerations and needs for future research. Family practice, 27(suppl_1), i23–i32.PubMedPubMedCentral Heisler, M. (2009). Different models to mobilize peer support to improve diabetes self-management and clinical outcomes: Evidence, logistics, evaluation considerations and needs for future research. Family practice, 27(suppl_1), i23–i32.PubMedPubMedCentral
55.
go back to reference Edinburgh (2006). Clinical diabetes: translating research into practice/Vivian A. Fonseca (1st edn.). Philadelphia: Elsevier Saunders. Edinburgh (2006). Clinical diabetes: translating research into practice/Vivian A. Fonseca (1st edn.). Philadelphia: Elsevier Saunders.
Metagegevens
Titel
Health-related quality of life among adults living with diabetic foot ulcers: a meta-analysis
Auteurs
Saneh Khunkaew
Ritin Fernandez
Jenny Sim
Publicatiedatum
18-12-2018
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 6/2019
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-018-2082-2

Andere artikelen Uitgave 6/2019

Quality of Life Research 6/2019 Naar de uitgave