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26-02-2018 | ORIGINAL PAPER

Genetic Variation of COMT Impacts Mindfulness and Self-Reported Everyday Cognitive Failures but Not Self-Rated Attentional Control

Auteurs: Cornelia Sindermann, Sebastian Markett, Sonja Jung, Christian Montag

Gepubliceerd in: Mindfulness | Uitgave 5/2018

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Abstract

The present study aimed to investigate potential associations between mindfulness and two prominent “cognitive” personality questionnaires (attentional control scale (ACS) and the cognitive failures questionnaire (CFQ)). Moreover, all participants (N = 537, n = 384 females; mean age = 23.30; SD = 5.15) provided buccal swaps for genotyping a classic polymorphism (COMT Val158Met/rs4680) known to influence dopaminergic catabolism on the biochemical level, as well as cognitive functions on a psychological level. Our results show that mindfulness is robustly linked to the ACS (positively) and the CFQ (negatively). The Met/Met genotype of the COMT polymorphism was associated with lower mindfulness (F(1, 535) = 8.27, p = .004; allele level) and higher everyday cognitive failure (F(1, 535) = 9.23, p = .003; allele level). But no significant effects of COMT Val158Met genotype could be observed for attentional control. The present findings provide evidence that the genetic COMT make up of a person could in parts explain self-reported skills in mindfulness and everyday cognitive failure. Based on the direction of the results, possible underlying factors are discussed. As such, COMT effects on an affective facet, which underlies mindfulness and everyday cognitive failures but not attentional control, may drive the effects. As still only a small part of the variance in the constructs is explained by the COMT polymorphism, potentially more genetic polymorphisms should additionally be taken into account in future studies to explain more variance. Genes involved in the dopaminergic neurotransmission seem to be an optimal starting point.
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Literatuur
go back to reference Amir, N., Beard, C., Cobb, M., & Bomyea, J. (2009). Attention modification program in individuals with generalized anxiety disorder. Journal of Abnormal Psychology, 118(1), 28–33.CrossRefPubMedPubMedCentral Amir, N., Beard, C., Cobb, M., & Bomyea, J. (2009). Attention modification program in individuals with generalized anxiety disorder. Journal of Abnormal Psychology, 118(1), 28–33.CrossRefPubMedPubMedCentral
go back to reference Arnsten, A. F. T. (1998). Catecholamine modulation of prefrontal cortical cognitive function. Trends in Cognitive Sciences, 2(11), 436–447.CrossRefPubMed Arnsten, A. F. T. (1998). Catecholamine modulation of prefrontal cortical cognitive function. Trends in Cognitive Sciences, 2(11), 436–447.CrossRefPubMed
go back to reference Baddeley, A. D., Baddeley, H. A., Bucks, R. S., & Wilcock, G. K. (2001). Attentional control in Alzheimer’s disease. Brain, 124, 1492–1508.CrossRefPubMed Baddeley, A. D., Baddeley, H. A., Bucks, R. S., & Wilcock, G. K. (2001). Attentional control in Alzheimer’s disease. Brain, 124, 1492–1508.CrossRefPubMed
go back to reference Baer, R. A., Smith, G. T., & Allen, K. B. (2004). Assessment of mindfulness by self-report: the Kentucky inventory of mindfulness skills. Assessment, 11(3), 191–206.CrossRefPubMed Baer, R. A., Smith, G. T., & Allen, K. B. (2004). Assessment of mindfulness by self-report: the Kentucky inventory of mindfulness skills. Assessment, 11(3), 191–206.CrossRefPubMed
go back to reference Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13(1), 27–45.CrossRefPubMed Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13(1), 27–45.CrossRefPubMed
go back to reference Bey, K., Montag, C., Reuter, M., Weber, B., & Markett, S. (2015). Susceptibility to everyday cognitive failure is reflected in functional network interactions in the resting brain. NeuroImage, 121, 1–9.CrossRefPubMed Bey, K., Montag, C., Reuter, M., Weber, B., & Markett, S. (2015). Susceptibility to everyday cognitive failure is reflected in functional network interactions in the resting brain. NeuroImage, 121, 1–9.CrossRefPubMed
go back to reference Bilder, R. M., Volavka, J., Lachman, H. M., & Grace, A. A. (2004). The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology, 29(11), 1943–1961.CrossRefPubMed Bilder, R. M., Volavka, J., Lachman, H. M., & Grace, A. A. (2004). The catechol-O-methyltransferase polymorphism: relations to the tonic-phasic dopamine hypothesis and neuropsychiatric phenotypes. Neuropsychopharmacology, 29(11), 1943–1961.CrossRefPubMed
go back to reference Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., Carmody, J., et al. (2004). Mindfulness: a proposed operational definition. Clinical psychology. Science and Practice, 11(3), 230–241. Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., Carmody, J., et al. (2004). Mindfulness: a proposed operational definition. Clinical psychology. Science and Practice, 11(3), 230–241.
go back to reference Blasi, G., Mattay, V. S., Bertolino, A., Elvevåg, B., Callicott, J. H., Das, S., et al. (2005). Effect of catechol-omethyltransferase val158met genotype on attentional control. Journal of Neuroscience, 25(20), 5038–5045.CrossRefPubMed Blasi, G., Mattay, V. S., Bertolino, A., Elvevåg, B., Callicott, J. H., Das, S., et al. (2005). Effect of catechol-omethyltransferase val158met genotype on attentional control. Journal of Neuroscience, 25(20), 5038–5045.CrossRefPubMed
go back to reference Boomsma, D. I. (1998). Genetic analysis of cognitive failures (CFQ): a study of Dutch adolescent twins and their parents. European Journal of Personality, 12(5), 321–330.CrossRef Boomsma, D. I. (1998). Genetic analysis of cognitive failures (CFQ): a study of Dutch adolescent twins and their parents. European Journal of Personality, 12(5), 321–330.CrossRef
go back to reference Bortz, J. (2005). Statistik für Human- und Sozialwissenschaftler. Heidelberg: SpringerMedizin. Bortz, J. (2005). Statistik für Human- und Sozialwissenschaftler. Heidelberg: SpringerMedizin.
go back to reference Bridger, R. S., Johnsen, S. A., & Brasher, K. (2013). Psychometric properties of the cognitive failure questionnaire. Ergonomics, 56(10), 1515–1524.CrossRefPubMed Bridger, R. S., Johnsen, S. A., & Brasher, K. (2013). Psychometric properties of the cognitive failure questionnaire. Ergonomics, 56(10), 1515–1524.CrossRefPubMed
go back to reference Broadbent, D. E., Cooper, P. F., FitzGerald, P., & Parkes, K. R. (1982). The cognitive failures questionnaire (CFQ) and its correlates. British Journal of Clinical Psychology, 21, 1–16.CrossRefPubMed Broadbent, D. E., Cooper, P. F., FitzGerald, P., & Parkes, K. R. (1982). The cognitive failures questionnaire (CFQ) and its correlates. British Journal of Clinical Psychology, 21, 1–16.CrossRefPubMed
go back to reference Brown, K. W., & Ryan, R. M. (2003). The benefits of being present: mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology, 84(4), 822–848.CrossRefPubMed Brown, K. W., & Ryan, R. M. (2003). The benefits of being present: mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology, 84(4), 822–848.CrossRefPubMed
go back to reference Brown, J. A., Emnett, R. J., White, C. R., Yuede, C. M., Conyers, S. B., O'Malley, K. L., et al. (2010). Reduced striatal dopamine underlies the attention system dysfunction in neurofibromatosis-1 mutant mice. Human Molecular Genetics, 19(22), 4515–4528.CrossRefPubMedPubMedCentral Brown, J. A., Emnett, R. J., White, C. R., Yuede, C. M., Conyers, S. B., O'Malley, K. L., et al. (2010). Reduced striatal dopamine underlies the attention system dysfunction in neurofibromatosis-1 mutant mice. Human Molecular Genetics, 19(22), 4515–4528.CrossRefPubMedPubMedCentral
go back to reference Chen, J., Lipska, B. K., Halim, N., Ma, Q. D., Matsumoto, M., Melhem, S., et al. (2004). Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. The American Journal of Human Genetics, 75(5), 807–821.CrossRefPubMed Chen, J., Lipska, B. K., Halim, N., Ma, Q. D., Matsumoto, M., Melhem, S., et al. (2004). Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. The American Journal of Human Genetics, 75(5), 807–821.CrossRefPubMed
go back to reference Crider, A., Blockel, L., & Solomon, P. R. (1986). A selective attention deficit in the rat following induced dopamine receptor supersensitivity. Behavioral Neuroscience, 100(3), 315–319.CrossRefPubMed Crider, A., Blockel, L., & Solomon, P. R. (1986). A selective attention deficit in the rat following induced dopamine receptor supersensitivity. Behavioral Neuroscience, 100(3), 315–319.CrossRefPubMed
go back to reference Derryberry, D., & Reed, M. A. (2001). A multidisciplinary perspective on attentional control. In C. Folk & B. Gibson (Eds.), Attraction, distraction, and action (volume 133): multiple perspectives on attentional capture (pp. 325–347). Amsterdam: Elsevier. Derryberry, D., & Reed, M. A. (2001). A multidisciplinary perspective on attentional control. In C. Folk & B. Gibson (Eds.), Attraction, distraction, and action (volume 133): multiple perspectives on attentional capture (pp. 325–347). Amsterdam: Elsevier.
go back to reference Derryberry, D., & Reed, M. A. (2002). Anxiety-related attentional biases and their regulation by attentional control. Journal of Abnormal Psychology, 111(2), 225–236.CrossRefPubMed Derryberry, D., & Reed, M. A. (2002). Anxiety-related attentional biases and their regulation by attentional control. Journal of Abnormal Psychology, 111(2), 225–236.CrossRefPubMed
go back to reference Evans, D. R., Baer, R. A., & Segerstrom, S. C. (2009). The effects of mindfulness and selfconsciousness on persistence. Personality and Individual Differences, 47(4), 379–382.CrossRef Evans, D. R., Baer, R. A., & Segerstrom, S. C. (2009). The effects of mindfulness and selfconsciousness on persistence. Personality and Individual Differences, 47(4), 379–382.CrossRef
go back to reference Goldman, D., Oroszi, G., & Ducci, F. (2005). The genetics of addictions: uncovering the genes. Nature Reviews, 6(5), 521–532.CrossRefPubMed Goldman, D., Oroszi, G., & Ducci, F. (2005). The genetics of addictions: uncovering the genes. Nature Reviews, 6(5), 521–532.CrossRefPubMed
go back to reference Herndon, F. (2008). Testing mindfulness with perceptual and cognitive factors: external vs. internal encoding, and the cognitive failures questionnaire. Personality and Individual Differences, 44(1), 32–41.CrossRef Herndon, F. (2008). Testing mindfulness with perceptual and cognitive factors: external vs. internal encoding, and the cognitive failures questionnaire. Personality and Individual Differences, 44(1), 32–41.CrossRef
go back to reference Jurado, M. B., & Rosselli, M. (2007). The elusive nature of executive functions: a review of our current understanding. Neuropsychology Review, 17(3), 213–233.CrossRefPubMed Jurado, M. B., & Rosselli, M. (2007). The elusive nature of executive functions: a review of our current understanding. Neuropsychology Review, 17(3), 213–233.CrossRefPubMed
go back to reference Kabat-Zinn, J. (2004). Wherever you go there you are: mindfulness meditation in everyday life. London: Piatkus Books. Kabat-Zinn, J. (2004). Wherever you go there you are: mindfulness meditation in everyday life. London: Piatkus Books.
go back to reference Keng, S.-L., Smoski, M. J., & Robins, C. J. (2011). Effects of mindfulness on psychological health: a review of empirical studies. Clinical Psychology Review, 31(6), 1041–1056.CrossRefPubMedPubMedCentral Keng, S.-L., Smoski, M. J., & Robins, C. J. (2011). Effects of mindfulness on psychological health: a review of empirical studies. Clinical Psychology Review, 31(6), 1041–1056.CrossRefPubMedPubMedCentral
go back to reference Klumb, P. L. (1995). Cognitive failures and performance differences: validation studies of a German version of the cognitive failures questionnaire. Ergonomics, 38(7), 1456–1467.CrossRefPubMed Klumb, P. L. (1995). Cognitive failures and performance differences: validation studies of a German version of the cognitive failures questionnaire. Ergonomics, 38(7), 1456–1467.CrossRefPubMed
go back to reference Krabbendam, L., Isusi, P., Galdos, P., Echevarria, E., Bilbao, J. R., Martin-Pagola, A., et al. (2006). Associations between COMTVal158Met polymorphism and cognition: direct or indirect effects? European Psychiatry, 21(5), 338–342.CrossRefPubMed Krabbendam, L., Isusi, P., Galdos, P., Echevarria, E., Bilbao, J. R., Martin-Pagola, A., et al. (2006). Associations between COMTVal158Met polymorphism and cognition: direct or indirect effects? European Psychiatry, 21(5), 338–342.CrossRefPubMed
go back to reference Lachman, H. M., Papolos, D. F., Saito, T., You, Y.-M., Szumlanski, C. L., & Weinshilboum, R. M. (1996). Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics, 6(3), 243–250.CrossRefPubMed Lachman, H. M., Papolos, D. F., Saito, T., You, Y.-M., Szumlanski, C. L., & Weinshilboum, R. M. (1996). Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics, 6(3), 243–250.CrossRefPubMed
go back to reference Lau, M. A., Bishop, S. R., Segal, Z. V., Buis, T., Anderson, N. D., Carlson, L., et al. (2006). The Toronto Mindfulness Scale: development and validation. Journal of Clinical Psychology, 62(12), 1445–1467.CrossRefPubMed Lau, M. A., Bishop, S. R., Segal, Z. V., Buis, T., Anderson, N. D., Carlson, L., et al. (2006). The Toronto Mindfulness Scale: development and validation. Journal of Clinical Psychology, 62(12), 1445–1467.CrossRefPubMed
go back to reference Lewis, D. A., Melchitzky, D. S., Sesack, S. R., Whitehead, R. E., Auh, S., & Sampson, A. (2001). Dopamine transporter immunoreactivity in monkey cerebral cortex: regional, laminar, and ultrastructural localization. Journal of Comparative Neurology, 432(1), 119–136.CrossRefPubMed Lewis, D. A., Melchitzky, D. S., Sesack, S. R., Whitehead, R. E., Auh, S., & Sampson, A. (2001). Dopamine transporter immunoreactivity in monkey cerebral cortex: regional, laminar, and ultrastructural localization. Journal of Comparative Neurology, 432(1), 119–136.CrossRefPubMed
go back to reference MacDonald, A. W., Cohen, J. D., Stenger, V. A., & Carter, C. S. (2000). Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control. Science, 288(5472), 1835–1838.CrossRefPubMed MacDonald, A. W., Cohen, J. D., Stenger, V. A., & Carter, C. S. (2000). Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control. Science, 288(5472), 1835–1838.CrossRefPubMed
go back to reference Malhotra, A. K., Kestler, L. J., Mazzanti, C., Bates, J. A., Goldberg, T., & Goldman, D. (2002). A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. American Journal of Psychiatry, 159(4), 652–654.CrossRefPubMed Malhotra, A. K., Kestler, L. J., Mazzanti, C., Bates, J. A., Goldberg, T., & Goldman, D. (2002). A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition. American Journal of Psychiatry, 159(4), 652–654.CrossRefPubMed
go back to reference Markett, S., Montag, C., & Reuter, M. (2011a). The nicotinic acetylcholine receptor gene CHRNA4 is associated with negative emotionality. Emotion, 11(2), 450–455.CrossRefPubMed Markett, S., Montag, C., & Reuter, M. (2011a). The nicotinic acetylcholine receptor gene CHRNA4 is associated with negative emotionality. Emotion, 11(2), 450–455.CrossRefPubMed
go back to reference Markett, S., Montag, C., Walter, N. T., Plieger, T., & Reuter, M. (2011b). On the molecular genetics of flexibility: the case of task switching, inhibitory control and genetic variants. Cognitive, Affective, & Behavioral Neuroscience, 11(4), 644–651.CrossRef Markett, S., Montag, C., Walter, N. T., Plieger, T., & Reuter, M. (2011b). On the molecular genetics of flexibility: the case of task switching, inhibitory control and genetic variants. Cognitive, Affective, & Behavioral Neuroscience, 11(4), 644–651.CrossRef
go back to reference Markett, S., Montag, C., Diekmann, C., & Reuter, M. (2014). Dazed and confused: a molecular genetic approach to everyday cognitive failure. Neuroscience Letters, 566, 216–220.CrossRefPubMed Markett, S., Montag, C., Diekmann, C., & Reuter, M. (2014). Dazed and confused: a molecular genetic approach to everyday cognitive failure. Neuroscience Letters, 566, 216–220.CrossRefPubMed
go back to reference Matthews, G., Coyle, K., & Craig, A. (1990). Multiple factors of cognitive failure and their relationships with stress vulnerability. Journal of Psychopathology and Behavioral Assessment, 12(1), 49–65.CrossRef Matthews, G., Coyle, K., & Craig, A. (1990). Multiple factors of cognitive failure and their relationships with stress vulnerability. Journal of Psychopathology and Behavioral Assessment, 12(1), 49–65.CrossRef
go back to reference McDonald, J. D. (2008). Measuring personality constructs: the advantages and disadvantages of self-reports, informant reports and behavioural assessments. Enquire, 1(1), 75–94. McDonald, J. D. (2008). Measuring personality constructs: the advantages and disadvantages of self-reports, informant reports and behavioural assessments. Enquire, 1(1), 75–94.
go back to reference Mier, D., Kirsch, P., & Meyer-Lindenberg, A. (2010). Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis. Molecular Psychiatry, 15(9), 918–927.CrossRefPubMed Mier, D., Kirsch, P., & Meyer-Lindenberg, A. (2010). Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis. Molecular Psychiatry, 15(9), 918–927.CrossRefPubMed
go back to reference Milham, M. P., Erickson, K. I., Banich, M. T., Kramer, A. F., Webb, A., Wszalek, T., & Cohen, N. J. (2002). Attentional control in the aging brain: insights from an fMRI study of the stroop task. Brain and Cognition, 49(3), 277–296.CrossRefPubMed Milham, M. P., Erickson, K. I., Banich, M. T., Kramer, A. F., Webb, A., Wszalek, T., & Cohen, N. J. (2002). Attentional control in the aging brain: insights from an fMRI study of the stroop task. Brain and Cognition, 49(3), 277–296.CrossRefPubMed
go back to reference Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., & Howerter, A. (2000). The unity and diversity of executive functions and their contributions to complex “Frontal Lobe” tasks: a latent variable analysis. Cognitive Psychology, 41(1), 49–100.CrossRefPubMed Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., & Howerter, A. (2000). The unity and diversity of executive functions and their contributions to complex “Frontal Lobe” tasks: a latent variable analysis. Cognitive Psychology, 41(1), 49–100.CrossRefPubMed
go back to reference Montag, C., & Reuter, M. (2014). Disentangling the molecular genetic basis of personality: from monoamines to neuropeptides. Neuroscience & Biobehavioral Reviews, 43, 228–239.CrossRef Montag, C., & Reuter, M. (2014). Disentangling the molecular genetic basis of personality: from monoamines to neuropeptides. Neuroscience & Biobehavioral Reviews, 43, 228–239.CrossRef
go back to reference Montag, C., Markett, S., Basten, U., Stelzel, C., Fiebach, C., Canli, T., & Reuter, M. (2010). Epistasis of the DRD2/ANKK1 Taq Ia and the BDNF Val66Met polymorphism impacts novelty seeking and harm avoidance. Neuropsychopharmacology, 35(9), 1860–1867.CrossRefPubMedPubMedCentral Montag, C., Markett, S., Basten, U., Stelzel, C., Fiebach, C., Canli, T., & Reuter, M. (2010). Epistasis of the DRD2/ANKK1 Taq Ia and the BDNF Val66Met polymorphism impacts novelty seeking and harm avoidance. Neuropsychopharmacology, 35(9), 1860–1867.CrossRefPubMedPubMedCentral
go back to reference Montag, C., Jurkiewicz, M., & Reuter, M. (2012). The role of the catechol-O-methyltransferase (COMT) gene in personality and related psychopathological disorders. CNS & Neurological Disorders - Drug Targets, 11(3), 236–250.CrossRef Montag, C., Jurkiewicz, M., & Reuter, M. (2012). The role of the catechol-O-methyltransferase (COMT) gene in personality and related psychopathological disorders. CNS & Neurological Disorders - Drug Targets, 11(3), 236–250.CrossRef
go back to reference Reuter, M., Schmitz, A., Corr, P., & Hennig, J. (2007). Molecular genetics support Gray’s personality theory: the interaction of COMT and DRD2 polymorphisms predicts the behavioural approach system. The International Journal of Neuropsychopharmacology, 9(2), 155–166. Reuter, M., Schmitz, A., Corr, P., & Hennig, J. (2007). Molecular genetics support Gray’s personality theory: the interaction of COMT and DRD2 polymorphisms predicts the behavioural approach system. The International Journal of Neuropsychopharmacology, 9(2), 155–166.
go back to reference Rueda, M. R., Posner, M. I., & Rothbart, M. K. (2004). Attentional control and selfregulation. In K. D. Vohs & R. F. Baumeister (Eds.), Handbook of self-regulation: research, theory, and applications (pp. 284–299). New Work: Guilford Press. Rueda, M. R., Posner, M. I., & Rothbart, M. K. (2004). Attentional control and selfregulation. In K. D. Vohs & R. F. Baumeister (Eds.), Handbook of self-regulation: research, theory, and applications (pp. 284–299). New Work: Guilford Press.
go back to reference Schmertz, S. K., Anderson, P. L., & Robins, D. L. (2009). The relation between self-report mindfulness and performance on tasks of sustained attention. Journal of Psychopathology and Behavioral Assessment, 31(1), 60–66.CrossRef Schmertz, S. K., Anderson, P. L., & Robins, D. L. (2009). The relation between self-report mindfulness and performance on tasks of sustained attention. Journal of Psychopathology and Behavioral Assessment, 31(1), 60–66.CrossRef
go back to reference Scholes, K. E., Harrison, B. J., O’Neill, B. V., Leung, S., Croft, R. J., Pipingas, A., et al. (2007). Acute serotonin and dopamine depletion improves attentional control: findings from the Stroop task. Neuropsychopharmacology, 32(7), 1600–1610.CrossRefPubMed Scholes, K. E., Harrison, B. J., O’Neill, B. V., Leung, S., Croft, R. J., Pipingas, A., et al. (2007). Acute serotonin and dopamine depletion improves attentional control: findings from the Stroop task. Neuropsychopharmacology, 32(7), 1600–1610.CrossRefPubMed
go back to reference Stelzel, C., Basten, U., Montag, C., Reuter, M., & Fiebach, C. J. (2009). Effects of dopamine related gene-gene interactions on working memory component processes. European Journal of Neuroscience, 29(5), 1056–1063.CrossRefPubMed Stelzel, C., Basten, U., Montag, C., Reuter, M., & Fiebach, C. J. (2009). Effects of dopamine related gene-gene interactions on working memory component processes. European Journal of Neuroscience, 29(5), 1056–1063.CrossRefPubMed
go back to reference Unsworth, N., Brewer, G. A., & Spillers, G. J. (2012a). Variation in cognitive failures: an individual differences investigation of everyday attention and memory failures. Journal of Memory and Language, 67(1), 1–16.CrossRef Unsworth, N., Brewer, G. A., & Spillers, G. J. (2012a). Variation in cognitive failures: an individual differences investigation of everyday attention and memory failures. Journal of Memory and Language, 67(1), 1–16.CrossRef
go back to reference Unsworth, N., McMillan, B. D., Brewer, G. A., & Spillers, G. J. (2012b). Everyday attention failures: an individual differences investigation. Journal of Experimental Psychology, 38(6), 1765–1772.PubMed Unsworth, N., McMillan, B. D., Brewer, G. A., & Spillers, G. J. (2012b). Everyday attention failures: an individual differences investigation. Journal of Experimental Psychology, 38(6), 1765–1772.PubMed
go back to reference Walsh, J. J., Balint, M. G., Smolira, D. R., Kamstrup Fredericksen, L., & Madsen, S. (2009). Predicting individual differences in mindfulness: the role of trait anxiety, attachment anxiety and attentional control. Personality and Individual Differences, 46(2), 94–99.CrossRef Walsh, J. J., Balint, M. G., Smolira, D. R., Kamstrup Fredericksen, L., & Madsen, S. (2009). Predicting individual differences in mindfulness: the role of trait anxiety, attachment anxiety and attentional control. Personality and Individual Differences, 46(2), 94–99.CrossRef
go back to reference Waszczuk, M. A., Zavos, H. M., Antonova, E., Haworth, C. M., Plomin, R., & Eley, T. C. (2015). A multivariate twin study of trait mindfulness, depressive symptoms, and anxiety sensitivity. Depression and Anxiety, 32(4), 254–261.CrossRefPubMedPubMedCentral Waszczuk, M. A., Zavos, H. M., Antonova, E., Haworth, C. M., Plomin, R., & Eley, T. C. (2015). A multivariate twin study of trait mindfulness, depressive symptoms, and anxiety sensitivity. Depression and Anxiety, 32(4), 254–261.CrossRefPubMedPubMedCentral
go back to reference Wilhelm, O., Witthöfft, M., & Schipolowski, S. (2010). Self-reported cognitive failures. Journal of Individual Differences, 31(1), 1–14.CrossRef Wilhelm, O., Witthöfft, M., & Schipolowski, S. (2010). Self-reported cognitive failures. Journal of Individual Differences, 31(1), 1–14.CrossRef
go back to reference Williams-Gray, C. H., Hampshire, A., Barker, R. A., & Owen, A. M. (2008). Attentional control in Parkinson’s disease is dependent on COMTval158met genotype. Brain, 131(2), 397–408.CrossRefPubMed Williams-Gray, C. H., Hampshire, A., Barker, R. A., & Owen, A. M. (2008). Attentional control in Parkinson’s disease is dependent on COMTval158met genotype. Brain, 131(2), 397–408.CrossRefPubMed
go back to reference Zhang, Y., Bertolino, A., Fazio, L., Blasi, G., Rampino, A., Romano, R., et al. (2007). Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory. Proceedings of the National Academy of Sciences, 104(51), 20552–20557.CrossRef Zhang, Y., Bertolino, A., Fazio, L., Blasi, G., Rampino, A., Romano, R., et al. (2007). Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory. Proceedings of the National Academy of Sciences, 104(51), 20552–20557.CrossRef
Metagegevens
Titel
Genetic Variation of COMT Impacts Mindfulness and Self-Reported Everyday Cognitive Failures but Not Self-Rated Attentional Control
Auteurs
Cornelia Sindermann
Sebastian Markett
Sonja Jung
Christian Montag
Publicatiedatum
26-02-2018
Uitgeverij
Springer US
Gepubliceerd in
Mindfulness / Uitgave 5/2018
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI
https://doi.org/10.1007/s12671-018-0893-4

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