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Journal of Autism and Developmental Disorders

Gepubliceerd in:

31-07-2022 | Original Paper

Dysbiosis in Gut Microbiota in Children Born Preterm Who Developed Autism Spectrum Disorder: A Pilot Study

Auteurs: Sadayuki Fujishiro, Shoji Tsuji, Shohei Akagawa, Yuko Akagawa, Sohsaku Yamanouchi, Yuko Ishizaki, Masaki Hashiyada, Atsushi Akane, Kazunari Kaneko

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2023

Abstract

The gut microbiota was reported to differ between children with autism spectrum disorder (ASD) and typically developing (TD) children, and dysbiosis of the gut microbiota in preterm infants is common. Here, we explored the characteristics of gut microbiota in children born preterm with ASD. We performed 16S rRNA gene sequencing using stool samples from ASD children born preterm and TD children born preterm. Alpha diversity was significantly greater in the ASD group. A comparison of beta diversity showed different clusters. Linear discriminant analysis effect size analysis revealed significantly more Firmicutes in the ASD group compared with the TD group. In conclusion, the gut microbiota in children born preterm differs between children with ASD and TD.

vorige artikel Evidence of a reduced role for circumscribed interests in the social attention patterns of children with Autism Spectrum Disorder

volgende artikel Structural Connectivity and Emotion Recognition Impairment in Children and Adolescents with Chromosome 22q11.2 Deletion Syndrome

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Titel: Dysbiosis in Gut Microbiota in Children Born Preterm Who Developed Autism Spectrum Disorder: A Pilot Study
Auteurs: Sadayuki Fujishiro
Shoji Tsuji
Shohei Akagawa
Yuko Akagawa
Sohsaku Yamanouchi
Yuko Ishizaki
Masaki Hashiyada
Atsushi Akane
Kazunari Kaneko
Publicatiedatum: 31-07-2022
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 10/2023
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-022-05682-0

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