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Gepubliceerd in: Journal of Autism and Developmental Disorders 3/2009

01-03-2009 | Original Paper

Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders

Auteurs: Roumen N. Nikolov, Karen E. Bearss, Jelle Lettinga, Craig Erickson, Maria Rodowski, Michael G. Aman, James T. McCracken, Christopher J. McDougle, Elaine Tierney, Benedetto Vitiello, L. Eugene Arnold, Bhavik Shah, David J. Posey, Louise Ritz, Lawrence Scahill

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2009

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Abstract

Objective To evaluate gastrointestinal (GI) problems in a large, well-characterized sample of children with pervasive developmental disorders (PDDs). Methods One hundred seventy two children entering one of two trials conducted by the Research Units on Pediatric Psychopharmacology (RUPP) Autism Network were assessed comprehensively prior to starting treatment and classified with regard to GI symptoms. Results Thirty nine (22.7%) were positive for GI problems, primarily constipation and diarrhea. Those with GI problems were no different from subjects without GI problems in demographic characteristics, measures of adaptive functioning, or autism symptom severity. Compared to children without GI problems, those with GI problems showed greater symptom severity on measures of irritability, anxiety, and social withdrawal. Those with GI problems were also less likely to respond to treatment.
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Metagegevens
Titel
Gastrointestinal Symptoms in a Sample of Children with Pervasive Developmental Disorders
Auteurs
Roumen N. Nikolov
Karen E. Bearss
Jelle Lettinga
Craig Erickson
Maria Rodowski
Michael G. Aman
James T. McCracken
Christopher J. McDougle
Elaine Tierney
Benedetto Vitiello
L. Eugene Arnold
Bhavik Shah
David J. Posey
Louise Ritz
Lawrence Scahill
Publicatiedatum
01-03-2009
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 3/2009
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-008-0637-8

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