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30-06-2017 | Uitgave 10/2017

Quality of Life Research 10/2017

Comparison of quality of life among community-dwelling older adults with the frailty phenotype

Quality of Life Research > Uitgave 10/2017
Sergio Sánchez-García, Katia Gallegos-Carrillo, María Claudia Espinel-Bermudez, Svetlana V. Doubova, Rosalinda Sánchez-Arenas, Carmen García-Peña, Antoni Salvà, Silvia C. Briseño-Fabian



To compare the perception of the quality of life (QOL) of community-dwelling older adults with the phenotype of frailty.


Cross-sectional analysis of baseline data of the “Cohort of Obesity, Sarcopenia and Frailty of Mexican Older Adults” (COSFOMA). Operationalization of frailty was carried out using the phenotype as follows: weight loss, self-report of exhaustion, low physical activity, slow gait, and weakness. QOL was measured using two scales: World Health Organization Quality of Life of Older Adults (WHOQOL-OLD), which is a specific instrument for the elderly population, and Short Form-36 Health Survey (SF-36), a generic instrument to evaluate the QOL related to health. One-way analyses of variance were conducted to assess the differences among the three phenotypes of frailty and QOL perception.


There were 1252 older adult participants who were analyzed; 11.2% (n = 140) had frailty, 50.3% (n = 630) pre-frailty and 38.5% (n = 482) were not frail. The mean (±SD) total score of the WHOQOL-OLD according to the phenotype of frailty was 60.3 (13.9) for those with frailty, 67.4 (12.7) pre-frailty and 72.4 (11.2) not frail (ANOVA, p < 0.001). The mean (±SD) of the SF-36 of the physical and mental component measures the sum, 38.9 (9.9) and 41.9 (11.3) with frailty, 45.7 (9.1) and 46.6 (9.8) pre-frailty, and 49.6 (7.3) and 49.4 (7.9) not frail, respectively (ANOVA, p < 0.001).


Frailty is observed in 1/10 community-dwelling older adults. Those with frailty and pre-frailty had a lower perception of QOL compared with those who were not frail.

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