Top

Gepubliceerd in:

29-07-2022 | Original Paper

Antipsychotic use among youth in foster care with comorbid ADHD and disruptive behavior disorder

Auteurs: Roderick A. Rose, Paul Lanier, Susan dosReis, Wouhib K. Tamrat

Gepubliceerd in: Journal of Child and Family Studies | Uitgave 7/2023

Abstract

Many youth with attention deficit hyperactivity disorder (ADHD) and disruptive behavior disorder (DBD) are treated with antipsychotic (AP) drugs. Among youth in foster care, a vulnerable group with high behavioral health service needs and utilization, the rate of AP prescribing is high, and is particularly so for youth with DBD. What is not clear is the specific role of DBD, and the timing of this diagnosis, in this prescribing pattern. In this study, we apply Cox proportional hazards regression models to 2011–2018 Medicaid claims data from a southeastern state to estimate the incidence of AP prescribing in a population of youth in foster care, and estimate the hazard rate of AP prescribing among youth in foster diagnosed with DBD following an ADHD diagnosis. DBD diagnosis was entered as a time-varying covariate. In this population, about 16% of youth were prescribed an AP, and 35% were diagnosed with DBD. Youth diagnosed with DBD have, on average, 4 times the rate of being prescribed an AP relative to those youth with ADHD who are not subsequently diagnosed with DBD. In light of the goal that youth with behavioral health needs be treated in the community, these trends are not surprising. Nevertheless, off-label prescribing of APs does come with health risks. Efforts should be made to improve access to alternative forms of care, and to support foster parents’ efforts to provide effective care. Additional research is needed to understand the complex processes by which foster youth with ADHD and DBD are prescribed APs.

vorige artikel Implicit Self Esteem Moderates the Association Between Explicit Self Esteem and Externalizing Behaviors

volgende artikel Development of Family Adaptability and Cohesion from Adolescence to Young Adulthood and Associations with Parental Behavior

American Academy of Child and Adolescent Psychiatry (2011). Practice parameter on the use of atypical antipsychotic medications in children and adolescents. Available at: https://www.aacap.org/App_Themes/AACAP/docs/practice_parameters/Atypical_Antipsychotic_Medications_Web.pdf. Accessed Aug. 28 2021.

American Academy of Child and Adolescent Psychiatry (2009). Practice parameter for the assessment and treatment of children and adolescents with Oppositional Defiant Disorder. Available at: https://www.aacap.org/App_Themes/AACAP/docs/practice_parameters/Atypical_Antipsychotic_Medications_Web.pdf. Accessed Aug. 28 2021.

Aitken, M., Waxman, J. A., MacDonald, K., & Andrade, B. F. (2018). Effect of comorbid psychopathology and conduct problem severity on response to a multi-component intervention for childhood disruptive behavior. Child Psychiatry & Human Development, 49(6), 853–864. https://doi.org/10.1007/s10578-018-0800-1.CrossRef

Allison, P. (1995). Survival analysis using the SAS System: A practical guide. The SAS Institute.

Bandou, N., Koike, K., & Matuura, H. (2010). Predictive familial risk factors and pharmacological responses in ADHD with comorbid disruptive behavior disorders: Pediatrics International, 52(3), 415–419. https://doi.org/10.1111/j.1442-200X.2009.03003.x.

Barnett, E. R., Butcher, R. L., Neubacher, K., Jankowski, M. K., Daviss, W. B., Carluzzo, K. L., Ungarelli, E. G., & Yackley, C. R. (2016). Psychotropic medications in child welfare: From federal mandate to direct care. Children and Youth Services Review, 66, 9–17. https://doi.org/10.1016/j.childyouth.2016.04.015.CrossRef

Brown, J. D., Hamilton, M., Natzke, B., Ireys, H. T., & Gillingham, M. (2011). Use of out-of-home care among a statewide population of children and youth enrolled in medicaid. Journal of Child and Family Studies, 20(1), 48–56. https://doi.org/10.1007/s10826-010-9376-5.CrossRef

Crystal, S., Mackie, T., Fenton, M. C., Amin, S., Neese-Todd, S., Olfson, M., & Bilder, S. (2016). Rapid growth of antipsychotic prescriptions for children who are publicly insured has ceased, but concerns remain. Health Affairs, 35(6), 974–982. https://doi.org/10.1377/hlthaff.2016.0064.CrossRefPubMed

Daviss, W. B., Barnett, E., Neubacher, K., & Drake, R. E. (2016). Use of antipsychotic medications for nonpsychotic children: risks and implications for mental health services. Psychiatric Services, 67(3), 339–341. https://doi.org/10.1176/appi.ps.201500272.CrossRefPubMed

dosReis, S., Yoon, Y., Rubin, D. M., Riddle, M. A., Noll, E., & Rothbard, A. (2011). Antipsychotic Treatment Among Youth in Foster Care. Pediatrics, 128(6), e1459–e1466. https://doi.org/10.1542/peds.2010-2970.CrossRefPubMedPubMedCentral

Farmer, E. M. Z., Wagner, H. R., Burns, B. J., & Richards, J. T. (2003). Treatment foster care in a system of care: sequences and correlates of residential placements. Journal of Child and Family Studies, 12(1), 11–15.CrossRef

Finnerty, M., Neese-Todd, S., Pritam, R., Leckman-Westin, E., Bilder, S., Byron, S. C., Hudson Scholle, S., Crystal, S., & Olfson, M. (2016). Access to psychosocial services prior to starting antipsychotic treatment among medicaid-insured youth. Journal of the American Academy of Child & Adolescent Psychiatry, 55(1), 69–76.e3. https://doi.org/10.1016/j.jaac.2015.09.020.CrossRef

Fong, H. F., Alegria, M., Bair-Merritt, M. H., & Beardslee, W. (2018). Factors associated with mental health services referrals for children investigated by child welfare. Child Abuse & Neglect, 79, 401–412. https://doi.org/10.1016/j.chiabu.2018.01.020.CrossRef

Fraser, M. W., Galinsky, M. J., Smokowski, P. R., Day, S. H., Terzian, M. A., Rose, R. A., & Guo, S. (2005). Social Information-Processing Skills Training to Promote Social Competence and Prevent Aggressive Behavior in the Third Grades. Journal of Consulting and Clinical Psychology, 73(6), 1045–1055. https://doi.org/10.1037/0022-006X.73.6.1045.CrossRefPubMed

Ghosh, A., Ray, A., & Basu, A. (2017). Oppositional defiant disorder: Current insight. Psychology Research and Behavior Management, ume 10, 353–367. https://doi.org/10.2147/PRBM.S120582.CrossRef

Huefner, J. C., Griffith, A. K., Smith, G. L., Vollmer, D. G., & Leslie, L. K. (2014). Reducing psychotropic medications in an intensive residential treatment center. Journal of Child and Family Studies, 23(4), 675–685. https://doi.org/10.1007/s10826-012-9628-7.CrossRef

Hulvershorn, L., Parkhurst, S., Jones, S., Dauss, K., & Adams, C. (2017). Improved metabolic and psychiatric outcomes with discontinuation of atypical antipsychotics in youth hospitalized in a state psychiatric facility. Journal of Child and Adolescent Psychopharmacology, 27(10), 897–907. https://doi.org/10.1089/cap.2017.0040.CrossRefPubMed

Lanier, P., Jensen, T., Bryant, K., Chung, G., Rose, R., Smith, Q., & Lackmann, L. (2020). A systematic review of the effectiveness of children’s behavioral health interventions in psychiatric residential treatment facilities. Children and Youth Services Review, 113, 104951 https://doi.org/10.1016/j.childyouth.2020.104951.CrossRef

Leathers, S. J., Vande Voort, B. L., & Melka-Kaffer, C. (2021). Mental health services and psychotropic medications provided to children at risk for placement instability in foster care. Developmental Child Welfare, 3(3), 256–281. https://doi.org/10.1177/25161032211034255.CrossRef

Lee, E. S., Vidal, C., & Findling, R. L. (2018). A focused review on the treatment of pediatric patients with atypical antipsychotics. Journal of Child and Adolescent Psychopharmacology, 28(9), 582–605. https://doi.org/10.1089/cap.2018.0037.CrossRefPubMed

Levesque, L. E., Hanley, J. A., Kezouh, A., & Suissa, S. (2010). Problem of immortal time bias in cohort studies: Example using statins for preventing progression of diabetes. BMJ, 340(mar12 1), b5087–b5087. https://doi.org/10.1136/bmj.b5087.CrossRefPubMed

Lohr, W. D., & Honaker, J. (2013). Atypical antipsychotics for the treatment of disruptive behavior. Pediatric Annals, 42(2), 72–77. https://doi.org/10.3928/00904481-20130128-11.CrossRefPubMed

Linares, L. O., Martinez-Martin, N., & Castellanos, F. X. (2013). Stimulant and atypical antipsychotic medications for children placed in foster homes. PLoS ONE, 8(1), e54152 https://doi.org/10.1371/journal.pone.0054152.CrossRefPubMedPubMedCentral

Linton, D., Barr, A. M., Honer, W. G., & Procyshyn, R. M. (2013). Antipsychotic and psychostimulant drug combination therapy in attention deficit/hyperactivity and disruptive behavior disorders: A systematic review of efficacy and tolerability. Current Psychiatry Reports, 15(5). https://doi.org/10.1007/s11920-013-0355-6.

Minjon, L., van den Ban, E., de Jong, E., Souverein, P. C., Egberts, T. C. G., & Heerdink, E. R. (2019). Reported adverse drug reactions in children and adolescents treated with antipsychotics. Journal of Child and Adolescent Psychopharmacology, 29(2), 124–132. https://doi.org/10.1089/cap.2018.0139.CrossRefPubMed

Moran, L. V., Ongur, D., Hsu, J., Castro, V. M., Perlis, R. H., & Schneeweiss, S. (2019). Psychosis with methylphenidate or amphetamine in patients with ADHD. New England Journal of Medicine, 380(12), 1128–1138. https://doi.org/10.1056/NEJMoa1813751.CrossRefPubMed

Olfson, M., Blanco, C., Liu, S.-M., Wang, S., & Correll, C. U. (2012). National trends in the office-based treatment of children, adolescents, and adults with antipsychotics. Archives of General Psychiatry, 69(12), 1247 https://doi.org/10.1001/archgenpsychiatry.2012.647.CrossRefPubMed

Rose, R., A., Lanier, P., & dosReis, S. (2022) Antipsychotic medications and admission to psychiatric residential treatment facilities among youth in foster care diagnosed with disruptive behavior disorders. American Journal of Orthopsychiatry. https://doi.org/10.1037/ort0000624.

Rose, R. & Lanier, P. (2017). A Longitudinal Study of Child Maltreatment and Mental Health Predictors of Admission to Psychiatric Residential Treatment Facilities. International Journal of Environmental Research and Public Health, 14(10), 1141. https://doi.org/10.3390/ijerph14101141.CrossRefPubMedPubMedCentral

Rose, R. A., Chung, G., & Lanier, P. J. (2020b). Effectiveness of Intensive Alternative Family Treatment on Reducing Re-Admissions to Psychiatric Residential Treatment Facilities. Journal of Emotional and Behavioral Disorders, Online First. https://doi.org/10.1177/1063426620980700.

Seibert, P. J., Feinberg, R., Ayub, A., Helburn, A., & Gibbs, D. (2018). State Practices in Treatment/Therapeutic Foster Care. Research Triangle Park, NC: RTI International.

Stroul, B. A., Blau, G. M., & Friedman, R. M. (2010). Updating the system of Care Concept and Philosophy. Washington, D.C.: National Technical Assistance Center for Children’s Mental Health.

Vanderwerker, L., Akincigil, A., Olfson, M., Gerhard, T., Neese-Todd, S., & Crystal, S. (2014). Foster care, externalizing disorders, and antipsychotic use among medicaid-enrolled youths. Psychiatric Services, 65(10), 1281–1284. https://doi.org/10.1176/appi.ps.201300455.CrossRefPubMed

Titel: Antipsychotic use among youth in foster care with comorbid ADHD and disruptive behavior disorder
Auteurs: Roderick A. Rose
Paul Lanier
Susan dosReis
Wouhib K. Tamrat
Publicatiedatum: 29-07-2022
Uitgeverij: Springer US
Gepubliceerd in: Journal of Child and Family Studies / Uitgave 7/2023
Print ISSN: 1062-1024
Elektronisch ISSN: 1573-2843
DOI: https://doi.org/10.1007/s10826-022-02375-1

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 7/2023

Home-based Parental Involvement and Early Adolescents’ Socio-emotional Adjustment at Middle School in China: A Longitudinal Exploration of Mediating Mechanisms

Development of Family Adaptability and Cohesion from Adolescence to Young Adulthood and Associations with Parental Behavior

Intergenerational Effects of Childhood Maltreatment: Role of Emotion Dysregulation and Emotion Socialization

Adolescent Academic Success: Teacher-Child Interactions as a Buffer for Early Childhood Relational Adversity

Exploring Links Between Social Avoidance and Socio-Emotional Functioning in Early Childhood: The Moderating Role of Maternal Depressive Symptoms

Examining the Psychosocial and Behavioral Factors Associated with Adolescent Engagement in Multiple Types of Cyberdeviance: Results from an Australian Study