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Gepubliceerd in:

04-09-2021

The role of future-oriented affect in engagement with genomic testing results

Auteurs: Arielle S. Gillman, Irina A. Iles, William M. P. Klein, Barbara B. Biesecker, Katie L. Lewis, Leslie G. Biesecker, Rebecca A. Ferrer

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 1/2022

Abstract

Future-oriented emotions such as anticipatory affect (i.e., current affect experienced regarding a potential future outcome) and anticipated affect (i.e., expectations about potential future affect), are uniquely associated with health decision-making (e.g., electing to receive results of genomic testing). This study investigated the degree to which negative anticipated and anticipatory emotions predict health decision making over time, and whether such emotions predict social, emotional, and behavioral responses to anticipated information (e.g., genomic testing results). 461 participants (M age = 63.9, SD = 5.61, 46% female) in a genomic sequencing cohort who elected to receive genomic sequencing (carrier) results were included in the current study. Anticipated and anticipatory affect about sequencing results were assessed at baseline. Psychological and behavioral responses to sequencing results, including participants’ reported anxiety, decisional conflict, and distress about sequencing results, whether they shared results with family members, and their intentions to continue learning results in the future, were collected immediately, one month, and/or six months after receiving results. More negative anticipated and anticipatory affect at baseline was significantly and independently associated with lower intentions to continue learning results in the future, as well as higher levels of anxiety and uncertainty at multiple time points after receiving results. Anticipated negative affect was also associated with greater decisional conflict, and anticipatory negative affect was also associated with greater distress after receiving results. Future-oriented emotions may play an important role in decisions that unfold over time, with implications for genomic testing, behavioral medicine, and health decision-making broadly.

vorige artikel Association of positive psychobehavioral factors and structural disadvantage with condomless sex in men who have sex men with childhood sexual abuse histories

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Arguably, this construct could also be represented with a categorical variable (no pathogenic/likely pathogenic results vs. one or more pathogenic/likely pathogenic results). Treating this covariate as a categorical variable did not meaningfully change our results.

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Titel: The role of future-oriented affect in engagement with genomic testing results
Auteurs: Arielle S. Gillman
Irina A. Iles
William M. P. Klein
Barbara B. Biesecker
Katie L. Lewis
Leslie G. Biesecker
Rebecca A. Ferrer
Publicatiedatum: 04-09-2021
Uitgeverij: Springer US
Gepubliceerd in: Journal of Behavioral Medicine / Uitgave 1/2022
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI: https://doi.org/10.1007/s10865-021-00253-7

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