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Quality of Life Research

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01-05-2010 | Brief Communication

Responsiveness of the EQ-5D and 8-item Parkinson’s Disease Questionnaire (PDQ-8) in a 4-year follow-up study

Auteurs: Nan Luo, Wai-Yee Ng, Puay-Ngoh Lau, Wing-Lok Au, Louis CS Tan

Gepubliceerd in: Quality of Life Research | Uitgave 4/2010

Abstract

Objective

The purpose of this study was to evaluate the responsiveness of the EQ-5D and the Parkinson’s Disease Questionnaire (PDQ-8) to deterioration in health-related quality of life (HRQoL) in patients with Parkinson’s disease (PD).

Methods

HRQoL and clinical data collected from 31 patients with PD (male: 74.2%, mean age: 61 years) who were surveyed with the EQ-5D and the PDQ-8 questionnaires in 2002 and 2006/2007 were analyzed. Responsiveness of the EQ-5D, PDQ-8, and Hoehn and Yahr (H&Y) staging were assessed according to Cohen’s effect size (ES) and standardized response mean (SRM).

Results

The mean (standard deviation) EQ-5D index and PDQ-8 summary index (PDQ-8SI) scores were 0.76 (0.23) and 17.7 (14.2) at baseline and 0.52 (0.33) and 35.1 (17.4) at year four. Based on both ES and SRM indices, the rank order of responsiveness of the studied measures, from high to low, was PDQ-8SI (ES = 1.22), EQ-5D index score (ES = 1.06), H&Y score (ES = 0.82), and the EQ-VAS score (ES = 0.24).

Conclusion

Both the EQ-5D and PDQ-8 are responsive to changes in health burden of the Parkinson’s disease over a 4-year period.

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Titel: Responsiveness of the EQ-5D and 8-item Parkinson’s Disease Questionnaire (PDQ-8) in a 4-year follow-up study
Auteurs: Nan Luo
Wai-Yee Ng
Puay-Ngoh Lau
Wing-Lok Au
Louis CS Tan
Publicatiedatum: 01-05-2010
Uitgeverij: Springer Netherlands
Gepubliceerd in: Quality of Life Research / Uitgave 4/2010
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-010-9615-7

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Abstract

Objective

Methods

Results

Conclusion

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