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Gepubliceerd in:

2016 | OriginalPaper | Hoofdstuk

4. Regeneratie van pulpaweefsel

Auteurs : N. Meschi, P. Lambrechts

Gepubliceerd in: Het tandheelkundig jaar 2017

Uitgeverij: Bohn Stafleu van Loghum

Samenvatting

De afgelopen vijftien jaar is er, met behulp van de ontwikkelingsbiologie en weefseltechnologie, een alternatieve therapie uitgewerkt voor het behandelen van geïnfecteerde, zeer immature, blijvende dentitie: de regeneratieve endodontische behandeling (REB). REB berust op vooral chemische desinfectie van het wortelkanaal en drie pijlers: stamcellen, groeifactoren en scaffolds. Het cell homing- en cell based-principe zijn de twee grote concepten van deze behandeling. Het cell based-principe berust op pulpaweefseltechnologie en -transplantatie en heeft tot nog toe vooral in vitro zijn toepassing. Het leidt tot gunstige resultaten voor weefselregeneratie. Vanwege ethische, financiële en infrastructurele beslommeringen, wordt klinisch eerder het cell homing-concept toegepast, wat leidt tot gunstige infectieheling, maar eerder herstel (dan regeneratie) van het pulpadentinecomplex. Omdat er langetermijnresultaten ontbreken en het evidentieniveau van REB nog laag is, is er behoefte aan klinisch, microbieel en translationeel onderzoek.

vorige hoofdstuk Wondhelingsproblemen in de mond

volgende hoofdstuk De meerwaarde van protocolmodificaties voor de behandeling van parodontitis

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Titel: Regeneratie van pulpaweefsel
Auteurs: N. Meschi
P. Lambrechts
Uitgeverij: Bohn Stafleu van Loghum
Boek: Het tandheelkundig jaar 2017
Print ISBN: 978-90-368-1029-6

Elektronisch ISBN: 978-90-368-1030-2

Copyright: 2016
DOI: https://doi.org/10.1007/978-90-368-1030-2_4

Bohn Stafleu van Loghum

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