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Research on Child and Adolescent Psychopathology

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02-04-2018

Neural Correlates of Attentional Processing of Threat in Youth with and without Anxiety Disorders

Auteurs: Michele Bechor, Michelle L. Ramos, Michael J. Crowley, Wendy K. Silverman, Jeremy W. Pettit, Bethany C. Reeb-Sutherland

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 1/2019

Abstract

Late-stage attentional processing of threatening stimuli, quantified through event-related potentials (ERPs), differentiates youth with and without anxiety disorders. It is unknown whether early-stage attentional processing of threatening stimuli differentiates these groups. Examining both early and late stage attentional processes in youth may advance knowledge and enhance efforts to identify biomarkers for translational prevention and treatment research. Twenty-one youth with primary DSM-IV-TR anxiety disorders (10 males, ages 8–15 years) and 21 typically developing Controls (15 males, ages 8–16 years) completed a dot probe task while electroencephalography (EEG) was recorded, and ERPs were examined. Youth with anxiety disorders showed significantly larger (more positive) P1 amplitudes for threatening stimuli than for neutral stimuli, and Controls showed the opposite pattern. Youth with anxiety showed larger (more negative) N170 amplitudes compared with Controls. Controls showed significantly larger (more positive) P2 and P3 amplitudes, regardless of stimuli valence, compared with youth with anxiety disorders. ERPs observed during the dot probe task indicate youth with anxiety disorders display distinct neural processing during early stage attentional orienting and processing of faces; this was not the case for Controls. Such results suggest these ERP components may have potential as biomarkers of anxiety disorders in youth.

vorige artikel Attenuated LPP to Emotional Face Stimuli Associated with Parent- and Self-Reported Depression in Children and Adolescents

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Titel: Neural Correlates of Attentional Processing of Threat in Youth with and without Anxiety Disorders
Auteurs: Michele Bechor
Michelle L. Ramos
Michael J. Crowley
Wendy K. Silverman
Jeremy W. Pettit
Bethany C. Reeb-Sutherland
Publicatiedatum: 02-04-2018
Uitgeverij: Springer US
Gepubliceerd in: Research on Child and Adolescent Psychopathology / Uitgave 1/2019
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI: https://doi.org/10.1007/s10802-018-0424-8

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