Skip to main content
Top

Tip

Swipe om te navigeren naar een ander artikel

Gepubliceerd in: Quality of Life Research 8/2008

01-10-2008

Metabolic syndrome is associated with impaired health-related quality of life: Lapinlahti 2005 study

Auteurs: Juhani Miettola, Leo K. Niskanen, Heimo Viinamäki, Harri Sintonen, Esko Kumpusalo

Gepubliceerd in: Quality of Life Research | Uitgave 8/2008

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Purpose

Association of Metabolic Syndrome (MetS) with Health-Related Quality of Life (HRQoL) is poorly documented. Our objective was to examine this association in an adult general population.

Methods

In our cross-sectional community-based health survey in a semirural Finnish community, we invited all the adults (n = 760) of eight birth cohorts between 30 and 65 years, of which 480 (63%) participated. A 15-dimensional, standardized HRQoL instrument (15D) was used to measure the main outcome, and the National Cholesterol Education Programme (NCEP) 2005 criteria were used for MetS classification.

Results

The prevalence of MetS was 38%. MetS was significantly associated with impaired HRQoL (P < 0.001) measured by the 15D score. Participants with MetS were statistically significantly worse off than participants without MetS in the dimensions of mobility (P < 0.001), hearing (P = 0.021), breathing (P < 0.001), usual activities (P = 0.001), discomfort and symptoms (P = 0.002), vitality (P = 0.003), and sexual activity (P = 0.008). In a logistic regression analysis, a significant association persisted between MetS and impaired HRQoL (OR = 1.9).

Conclusions

MetS seems to be associated closely with perceived HRQoL at community level. Therefore, reduction of risk factors of MetS may improve HRQoL.
Literatuur
3.
go back to reference Laaksonen, D. E., Lakka, H. M., Niskanen, L. K., Kaplan, G. A., Salonen, J. T., & Lakka, T. A. (2002). Metabolic syndrome and development of diabetes mellitus: Application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. American Journal of Epidemiology, 156, 1070–1077. doi: 10.​1093/​aje/​kwf145. PubMedCrossRef Laaksonen, D. E., Lakka, H. M., Niskanen, L. K., Kaplan, G. A., Salonen, J. T., & Lakka, T. A. (2002). Metabolic syndrome and development of diabetes mellitus: Application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. American Journal of Epidemiology, 156, 1070–1077. doi: 10.​1093/​aje/​kwf145. PubMedCrossRef
5.
go back to reference Lakka, H.-M., Laaksonen, D. E., Lakka, T. A., Niskanen, L. K., Kumpusalo, E., Tuomilehto, J., et al. (2002). The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. Journal of the American Medical Association, 288, 2709–2716. doi: 10.​1001/​jama.​288.​21.​2709. PubMedCrossRef Lakka, H.-M., Laaksonen, D. E., Lakka, T. A., Niskanen, L. K., Kumpusalo, E., Tuomilehto, J., et al. (2002). The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. Journal of the American Medical Association, 288, 2709–2716. doi: 10.​1001/​jama.​288.​21.​2709. PubMedCrossRef
9.
go back to reference Larsson, U., Karlsson, J., & Sullivan, M. (2002). Impact of overweight and obesity on health-related quality of life—a Swedish population study. International Journal of Obesity and Related Metabolic Disorders, 26, 417–424. doi: 10.​1038/​sj.​ijo.​0801919. PubMedCrossRef Larsson, U., Karlsson, J., & Sullivan, M. (2002). Impact of overweight and obesity on health-related quality of life—a Swedish population study. International Journal of Obesity and Related Metabolic Disorders, 26, 417–424. doi: 10.​1038/​sj.​ijo.​0801919. PubMedCrossRef
10.
go back to reference Baiardi, F., Puglia, M. G., Valpiani, G., Sturani, A., Baraccani, C., Gentile, M., et al. (2005). Relationship between body weight, quality of life and cardiovascular risk factors: A general population based Italian experience. Eating and Weight Disorders, 10, 19–24. PubMed Baiardi, F., Puglia, M. G., Valpiani, G., Sturani, A., Baraccani, C., Gentile, M., et al. (2005). Relationship between body weight, quality of life and cardiovascular risk factors: A general population based Italian experience. Eating and Weight Disorders, 10, 19–24. PubMed
12.
13.
go back to reference Ford, E. S., Moriarty, D. G., Zack, M. M., Mokdad, A. H., & Chapman, D. P. (2001). Self-reported body mass index and health-related quality of life: Findings from the behavioural risk factor surveillance system. Obesity Research, 9, 21–31. doi: 10.​1038/​oby.​2001.​4. PubMedCrossRef Ford, E. S., Moriarty, D. G., Zack, M. M., Mokdad, A. H., & Chapman, D. P. (2001). Self-reported body mass index and health-related quality of life: Findings from the behavioural risk factor surveillance system. Obesity Research, 9, 21–31. doi: 10.​1038/​oby.​2001.​4. PubMedCrossRef
14.
go back to reference Mena-Martin, F. J., Martin-Escudero, J. C., Simal-Blanco, F., Carretero-Ares, J. L., Arzua-Mouronte, D., & Herreros-Fernandez, V. (2003). Health-related quality of life of subjects with known and unknown hypertension: Results from the population-based Hortega study. Journal of Hypertension, 21, 1283–1289. doi: 10.​1097/​00004872-200307000-00015. PubMedCrossRef Mena-Martin, F. J., Martin-Escudero, J. C., Simal-Blanco, F., Carretero-Ares, J. L., Arzua-Mouronte, D., & Herreros-Fernandez, V. (2003). Health-related quality of life of subjects with known and unknown hypertension: Results from the population-based Hortega study. Journal of Hypertension, 21, 1283–1289. doi: 10.​1097/​00004872-200307000-00015. PubMedCrossRef
16.
go back to reference Lalonde, L., Clarke, A. E., Joseph, L., Mackenzie, T., & Grover, S. A. (2001). Canadian Collaborative Cardiac Assessment Group. Health-related quality of life with coronary heart disease prevention and treatment. Journal of Clinical Epidemiology, 54, 1011–1018. doi: 10.​1016/​S0895-4356(01)00361-4. PubMedCrossRef Lalonde, L., Clarke, A. E., Joseph, L., Mackenzie, T., & Grover, S. A. (2001). Canadian Collaborative Cardiac Assessment Group. Health-related quality of life with coronary heart disease prevention and treatment. Journal of Clinical Epidemiology, 54, 1011–1018. doi: 10.​1016/​S0895-4356(01)00361-4. PubMedCrossRef
17.
go back to reference Svartvik, L., Lidfeldt, J., Nerbrand, C., Samsioe, G., Schersten, B., & Nilsson, P. M. (2000). Dyslipidaemia and impaired well-being in middle-aged women reporting low sense of coherence. The Women’s Health in the Lund Area (WHLA). Scandinavian Journal of Primary Health Care, 18, 177–182. doi: 10.​1080/​028134300453395. PubMedCrossRef Svartvik, L., Lidfeldt, J., Nerbrand, C., Samsioe, G., Schersten, B., & Nilsson, P. M. (2000). Dyslipidaemia and impaired well-being in middle-aged women reporting low sense of coherence. The Women’s Health in the Lund Area (WHLA). Scandinavian Journal of Primary Health Care, 18, 177–182. doi: 10.​1080/​028134300453395. PubMedCrossRef
18.
go back to reference Cox, D., Gonder-Frederick, L., McCall, A., Kovatchev, B., & Clarke, W. (2002). The effects of glucose fluctuation on cognitive function and QOL: The functional costs of hypoglycaemia and hyperglycaemia among adults with type 1 or type 2 diabetes. International Journal of Clinical Practice. Supplement, 129, 20–26. PubMed Cox, D., Gonder-Frederick, L., McCall, A., Kovatchev, B., & Clarke, W. (2002). The effects of glucose fluctuation on cognitive function and QOL: The functional costs of hypoglycaemia and hyperglycaemia among adults with type 1 or type 2 diabetes. International Journal of Clinical Practice. Supplement, 129, 20–26. PubMed
19.
go back to reference Schlotz, W., Ambery, P., Syddall, H. E., Crozier, S. R., Sayer, A. A., Cooper, C., et al. (2007). Specific associations of insulin resistance with impaired health-related quality of life in the Hertfordshire Cohort Study. Quality of Life Research, 16, 429–436. doi: 10.​1007/​s11136-006-9129-5. PubMedCrossRef Schlotz, W., Ambery, P., Syddall, H. E., Crozier, S. R., Sayer, A. A., Cooper, C., et al. (2007). Specific associations of insulin resistance with impaired health-related quality of life in the Hertfordshire Cohort Study. Quality of Life Research, 16, 429–436. doi: 10.​1007/​s11136-006-9129-5. PubMedCrossRef
21.
go back to reference Sintonen, H. (1994). Outcome measurement in acid-related diseases. PharmacoEconomics, 5, 17–26. CrossRef Sintonen, H. (1994). Outcome measurement in acid-related diseases. PharmacoEconomics, 5, 17–26. CrossRef
22.
go back to reference Aromaa, A., & Koskinen, S. (2004). Health and functional capacity in Finland. Baseline results of the Health 2000 health examination survey (p. 171). Publications of National Public Health Institute, Series B 12/2004. Aromaa, A., & Koskinen, S. (2004). Health and functional capacity in Finland. Baseline results of the Health 2000 health examination survey (p. 171). Publications of National Public Health Institute, Series B 12/2004.
25.
go back to reference Ilanne-Parikka, P., Eriksson, J. G., Lindstrom, J., Hamalainen, H., Keinanen-Kiukaanniemi, S., Laakso, M., et al. (2004). Prevalence of the metabolic syndrome and its components: Findings from a Finnish general population sample and the Diabetes Prevention Study cohort. Diabetes Care, 27, 2135–2140. doi: 10.​2337/​diacare.​27.​9.​2135. PubMedCrossRef Ilanne-Parikka, P., Eriksson, J. G., Lindstrom, J., Hamalainen, H., Keinanen-Kiukaanniemi, S., Laakso, M., et al. (2004). Prevalence of the metabolic syndrome and its components: Findings from a Finnish general population sample and the Diabetes Prevention Study cohort. Diabetes Care, 27, 2135–2140. doi: 10.​2337/​diacare.​27.​9.​2135. PubMedCrossRef
28.
go back to reference Spencer, J. T., Jr. (2007). Metabolic-syndromic sensorineural hearing loss and increased noise vulnerability. Ear, Nose, and Throat Journal, 86, 314. PubMed Spencer, J. T., Jr. (2007). Metabolic-syndromic sensorineural hearing loss and increased noise vulnerability. Ear, Nose, and Throat Journal, 86, 314. PubMed
30.
33.
go back to reference Esposito, K., Giugliano, F., Di Palo, C., Giugliano, G., Marfella, R., D’Andrea, F., et al. (2004). Effect of life style changes on erectile dysfunction in obese men: A randomized controlled trial. Journal of the American Medical Association, 291, 2978–2984. doi: 10.​1001/​jama.​291.​24.​2978. PubMedCrossRef Esposito, K., Giugliano, F., Di Palo, C., Giugliano, G., Marfella, R., D’Andrea, F., et al. (2004). Effect of life style changes on erectile dysfunction in obese men: A randomized controlled trial. Journal of the American Medical Association, 291, 2978–2984. doi: 10.​1001/​jama.​291.​24.​2978. PubMedCrossRef
34.
go back to reference Niskanen, L., Laaksonen, D. E., Punnonen, K., Mustajoki, P., Kaukua, J., & Rissanen, A. (2004). Changes in sex hormone-binding globulin and testosterone during weight loss and weight maintenance in abdominally obese men with the metabolic syndrome. Diabetes, Obesity & Metabolism, 6, 208–215. doi: 10.​1111/​j.​1462-8902.​2004.​00335.​x. CrossRef Niskanen, L., Laaksonen, D. E., Punnonen, K., Mustajoki, P., Kaukua, J., & Rissanen, A. (2004). Changes in sex hormone-binding globulin and testosterone during weight loss and weight maintenance in abdominally obese men with the metabolic syndrome. Diabetes, Obesity & Metabolism, 6, 208–215. doi: 10.​1111/​j.​1462-8902.​2004.​00335.​x. CrossRef
35.
go back to reference Korhonen, S., Hippelainen, M., Vanhala, M., Heinonen, S., & Niskanen, L. (2003). The androgenic sex hormone profile is an essential feature of metabolic syndrome in premenopausal women: A controlled community-based study. Fertility and Sterility, 79, 1327–1334. doi: 10.​1016/​S0015-0282(03)00347-9. PubMedCrossRef Korhonen, S., Hippelainen, M., Vanhala, M., Heinonen, S., & Niskanen, L. (2003). The androgenic sex hormone profile is an essential feature of metabolic syndrome in premenopausal women: A controlled community-based study. Fertility and Sterility, 79, 1327–1334. doi: 10.​1016/​S0015-0282(03)00347-9. PubMedCrossRef
Metagegevens
Titel
Metabolic syndrome is associated with impaired health-related quality of life: Lapinlahti 2005 study
Auteurs
Juhani Miettola
Leo K. Niskanen
Heimo Viinamäki
Harri Sintonen
Esko Kumpusalo
Publicatiedatum
01-10-2008
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 8/2008
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-008-9386-6

Andere artikelen Uitgave 8/2008

Quality of Life Research 8/2008 Naar de uitgave