Skip to main content
Top
Gepubliceerd in: Bijblijven 7/2012

01-11-2012

Levercirrose

Auteurs: Prof. dr. P. Michielsen, prof. dr. S.M.A. Francque

Gepubliceerd in: Bijblijven | Uitgave 7/2012

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Samenvatting

Cirrose is een diffuus leverproces gekenmerkt door fibrose en vorming van regeneratienodulen. De wereldwijde prevalentie is ongeveer 100/100.000 inwoners. De frequentste oorzaken zijn chronische hepatitis B en C, alcoholisch leverlijden, en nu ook niet-alcoholische streatohepatitis. Een cirrose kan lange tijd gecompenseerd blijven; wanneer zich verwikkelingen voordoen zoals varices, ascites, icterus of hepatocellulair carcinoom spreekt men van een gedecompenseerde cirrose en is de prognose sterk verminderd. Deze bijdrage gaat in op de diagnosestelling en prognosebepaling bij patiënten met cirrose. Ten slotte worden enkele specifieke elementen van behandeling en opvolging besproken.
Literatuur
1.
go back to reference Laënnec RTH. Traité de l’auscultation médiate et des maladies des poumons et du coeur. Parijs: J.S. Chaudé; 1819. Laënnec RTH. Traité de l’auscultation médiate et des maladies des poumons et du coeur. Parijs: J.S. Chaudé; 1819.
2.
go back to reference La Vecchia C, Levi F, Lucchini F, Franceschi S, Negri E. Worldwide patterns and trends in mortality from liver cirrhosis, 1955 to 1990. Ann Epidemiol 1994;4:480-6.PubMedCrossRef La Vecchia C, Levi F, Lucchini F, Franceschi S, Negri E. Worldwide patterns and trends in mortality from liver cirrhosis, 1955 to 1990. Ann Epidemiol 1994;4:480-6.PubMedCrossRef
3.
go back to reference D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indications of survival in cirrhosis. A systematic review of 118 studies. J Hepatol 2006;44:217-31.PubMedCrossRef D’Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indications of survival in cirrhosis. A systematic review of 118 studies. J Hepatol 2006;44:217-31.PubMedCrossRef
4.
go back to reference Corrao G, Ferrari P, Zambon A, Torchio P. Trends of liver cirrhosis and mortality in Europe, 1970-1989; age-period-cohort analysis and changing alcohol consumption. Int J Epidemiol 1997;26:100-9.PubMedCrossRef Corrao G, Ferrari P, Zambon A, Torchio P. Trends of liver cirrhosis and mortality in Europe, 1970-1989; age-period-cohort analysis and changing alcohol consumption. Int J Epidemiol 1997;26:100-9.PubMedCrossRef
5.
go back to reference Caldwell SH, Crespo DM. The spectrum expanded: cryptogenic cirrhosis and the natural history of non-alcoholic fatty liver disease. J Hepatol 2004;40:578-84.PubMedCrossRef Caldwell SH, Crespo DM. The spectrum expanded: cryptogenic cirrhosis and the natural history of non-alcoholic fatty liver disease. J Hepatol 2004;40:578-84.PubMedCrossRef
7.
go back to reference D’Amico G, Garcia-Tsao G, Pagliari L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006;44:217-31.PubMedCrossRef D’Amico G, Garcia-Tsao G, Pagliari L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol 2006;44:217-31.PubMedCrossRef
8.
go back to reference Garcia-Tsao G, Sanyal AJ, Grace ND, Carey W, The Practice Guidelines Committee of the American Association for the Study of the Liver, The Practice Parameter Committee of the American College of Gastroenterology. AASLD Practice Guidelines. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis, 2007, reviewed 2009. Beschikbaar via: http://www.aasld.org/practiceguidelines. Garcia-Tsao G, Sanyal AJ, Grace ND, Carey W, The Practice Guidelines Committee of the American Association for the Study of the Liver, The Practice Parameter Committee of the American College of Gastroenterology. AASLD Practice Guidelines. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis, 2007, reviewed 2009. Beschikbaar via: http://​www.​aasld.​org/​practiceguidelin​es.
10.
go back to reference Castera L, Bedossa P. How to assess liver fibrosis in chronic hepatitis C: serum markers or transient elastography vs liver biopsy? Liver Int 2001;31(Suppl 1):13-7. Castera L, Bedossa P. How to assess liver fibrosis in chronic hepatitis C: serum markers or transient elastography vs liver biopsy? Liver Int 2001;31(Suppl 1):13-7.
11.
go back to reference Ganne-Carrié N, Ziol M, Lédinghen V de, Douvin C, Marcellin P, Castera L, et al. Accuracy of liver stiffness measurement for the diagnosis in patients with chronic liver diseases. Hepatology 2006;44:1511-7.PubMedCrossRef Ganne-Carrié N, Ziol M, Lédinghen V de, Douvin C, Marcellin P, Castera L, et al. Accuracy of liver stiffness measurement for the diagnosis in patients with chronic liver diseases. Hepatology 2006;44:1511-7.PubMedCrossRef
12.
go back to reference Pugh RNH, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transsection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973;60:646-9.PubMedCrossRef Pugh RNH, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transsection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973;60:646-9.PubMedCrossRef
13.
go back to reference Kamath PS, Kim WR, Advanced Liver Disease Study Group. The Model for End stage Liver Disease (MELD). Hepatology 2007;45:797-805.PubMedCrossRef Kamath PS, Kim WR, Advanced Liver Disease Study Group. The Model for End stage Liver Disease (MELD). Hepatology 2007;45:797-805.PubMedCrossRef
Metagegevens
Titel
Levercirrose
Auteurs
Prof. dr. P. Michielsen
prof. dr. S.M.A. Francque
Publicatiedatum
01-11-2012
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Bijblijven / Uitgave 7/2012
Print ISSN: 0168-9428
Elektronisch ISSN: 1876-4916
DOI
https://doi.org/10.1007/s12414-012-0059-6

Andere artikelen Uitgave 7/2012

Bijblijven 7/2012 Naar de uitgave

OriginalPaper

Buikpijn