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21-02-2022 | ORIGINAL PAPER

Higher Serum Antioxidant Capacity Levels and Its Association with Serum NOx Levels Among Long-term Experienced Meditators in Sri Lanka

Auteurs: James C. Thambyrajah, Shiroma M. Handunnetti, Hewa W. Dilanthi, Dilshani W. N. Dissanayake

Gepubliceerd in: Mindfulness | Uitgave 4/2022

Abstract

Objectives

Recent medical research into meditation based on stress, pain, coping, and quality of life has shown an overall positive impact on health and immunological outcomes including oxidative stress. This study was aimed to assess the total nitric oxide, nitrite levels, and antioxidant capacity in experienced meditators compared to an age-, gender-, and education level–matched non-meditating group and to determine relationship between these parameters.

Methods

The total serum nitric oxide (NOx:NO₃⁻ + NO₂⁻) and nitrite (NO₂⁻) levels of long-term, experienced meditators (n = 12), recruited using a validated interview, and age-, gender-, and educational level–matched control subjects (n = 12) who had never practiced meditation, were determined using the modified Griess and Griess assay respectively. The Trolox equivalent antioxidant capacity (TEAC) was determined using the ABTS assay using Trolox as a standard.

Results

Serum NOx 5.03 ± 0.31 (mean ± SD) and nitrite levels 0.52 ± 0.05 of the meditators were significantly lower and TEAC values 424.35 ± 41.53 of the meditators were significantly higher compared to control group who had serum NOx levels of 5.42 ± 0.42 (p = 0.016, d = − 1.05), nitrite levels of 0.92 ± 0.52 (p = 0.014, d = − 1.08), and TEAC values of 376.15 ± 12.69 (p = 0.001, d = 1.57). There was a correlation of the TEAC levels with NO₂⁻ (r = 0.562; d = 0.316) and NOx (r = 0.664; d = 0.441).

Conclusions

These findings indicate a lower production of nitric oxide and a higher serum antioxidant capacity in the long-term meditators with potential beneficial effects against oxidative stress.

vorige artikel Training Self-compassion: Exploring the Effects on Adolescents’ Physiological and Self-reported Stress Responses

volgende artikel Women, Painful Sex, and Mindfulness

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Titel: Higher Serum Antioxidant Capacity Levels and Its Association with Serum NOx Levels Among Long-term Experienced Meditators in Sri Lanka
Auteurs: James C. Thambyrajah
Shiroma M. Handunnetti
Hewa W. Dilanthi
Dilshani W. N. Dissanayake
Publicatiedatum: 21-02-2022
Uitgeverij: Springer US
Gepubliceerd in: Mindfulness / Uitgave 4/2022
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI: https://doi.org/10.1007/s12671-022-01840-8

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Abstract

Objectives

Methods

Results

Conclusions

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