Swipe om te navigeren naar een ander artikel
This study examined the relationship of post-traumatic and depressive symptom severity with measures of health-related quality of life (HRQOL), and health care utilization in a sample of 503 HIV-infected men who have sex with men (MSM) recruited in their primary HIV care setting. Participants completed computer assisted assessments of mood and anxiety, HRQOL, and HIV treatment. Peripheral blood CD4 (T helper) lymphocyte count, plasma HIV RNA concentration, and number of medical appointments were extracted from an electronic medical record. Controlling for demographics, disease stage, and antiretroviral medication, post-traumatic stress and depression symptoms accounted for significant variation in general health estimates, and in pain, role, and work-related impairment. Additionally, in multivariable models, post-traumatic stress and depression severity accounted for significant variation in health care utilization whereas symptoms and indices of HIV disease progression did not. These results extend the current research by providing evidence of the relationship between post-traumatic stress and depression symptom severity with measures of functional impairment and health care utilization in a relatively healthy, urban cohort of HIV-infected MSM.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Centers for Disease Control (CDC). (2007). Fact sheet: HIV/AIDS among men who have sex with men. June 2007.
Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., & Zwickl, B. (2000). Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG adherence instruments. AIDS Care, 12, 255–266. doi: 10.1080/09540120050042891. PubMedCrossRef
Cole, S. W., Naliboff, B. D., Kemeny, M. E., Griswold, M. P., Fahey, J. L., & Zack, J. A. (2001). Impaired response to HAART in HIV-infected individuals with high autonomic nervous system activity. Proceedings of the National Academy of Sciences of the United States of America, 98, 12695–12700. doi: 10.1073/pnas.221134198. PubMedCrossRef
Gill, C. J., Griffith, J. L., Jacobson, D., Skinner, S., Grobach, S. L., & Wilson, I. B. (2002). Relationship of HIV viral loads, CD4 counts, and HAART use to health-related quality of life. Journal of Acquired Immune Deficiency Syndrome, 30, 485–492.
Ibnanez, G. E., Purcell, D. W., Stall, R., Parsons, J. T., & Gomez, C. A. (2005). Sexual risk, substance use, psychological distress in HIV-positive gay and bisexual men who also inject drugs. AIDS (London, England), 19, S49–S55.
Ironson, G., O’Cleirigh, C., Fletcher, M. A., Laurenceau, J. P., Balbin, E., Klimas, N., et al. (2005). Psychosocial factors predict CD4 and viral load change in men and women with HIV in the era of HAART. Psychosomatic Medicine, 67, 1013–1021. doi: 10.1097/01.psy.0000188569.58998.c8. PubMedCrossRef
Ironson, G., O’Cleirigh, C., Kumar, M., Balbin, E., Schneiderman, N., & Fletcher, M. A. (2006). Depression, coping, and neurohormonal predictors of HIV disease progression over 4 years in a diverse sample. Toronto, Canada: Presented at XVI International AIDS Conference.
Jacobson, D. L., Wu, A. W., & Feinberg, J. (2003). Health-related quality of life predicts survival, cytomegalovirus disease, and study retention in clinical trial participants with advanced HIV disease. Journal of Clinical Epidemiology, 56, 874–879. doi: 10.1016/S0895-4356(03)00062-3. PubMedCrossRef
Kelly, B., Raphael, B., Judd, F., Kernutt, G., Burnett, P., & Burrows, G. (1998). Suicidal ideation, suicide attempts, and HIV infection. Psychosomatics, 39, 405–415. PubMed
Kemeny, M. E., & Dean, L. (1995). Effects of AIDS-related bereavement on HIV progression among New York city gay men. AIDS Education and Prevention, 7(suppl), 36–47. PubMed
Knauz, R. O., Safren, S. A., O’Cleirigh, C., Capistrant, B. D., Driskell, J. R., Aguilar, D., et al. (2007). Developing an HIV-prevention intervention for HIV-infected men who have sex with men: Project enhance. AIDS and Behavior, 5(Supp.), 117–126. CrossRef
Leserman, J., Jackson, E. D., Petitto, J. M., Golden, R. N., Silva, S. G., Perkins, D. O., et al. (1999). Progression to AIDS: The effects of stress, depressive symptoms, and social support. Psychosomatic Medicine, 61, 397–406. PubMed
Leserman, J., Petitto, J. M., Golden, R. N., Gaynes, B. N., Gu, H., Perkins, D. O., et al. (2000). Impact of stressful life events, depression, social support, coping and cortisol on progression to AIDS. The American Journal of Psychiatry, 157(8), 1221–1228. doi: 10.1176/appi.ajp.157.8.1221. PubMedCrossRef
Leserman, J., Whetten, K., Lowe, K., Stangl, D., Swartz, M., & Theilman, N. (2005). How trauma, recent stressful events, and PTSD affect functional health and health utilization in HIV-infected patients in the south. Psychosomatic Medicine, 67, 500–507. doi: 10.1097/01.psy.0000160459.78182.d9. PubMedCrossRef
Liebschutz, J. M., Feinman, G., Sullivan, L., Stein, M., & Samet, J. (2000). Physical and sexual abuse in women infected with the human immunodeficiency virus–Increased illness and health care utilization. Archives of Internal Medicine, 160, 1659–1664. doi: 10.1001/archinte.160.11.1659. PubMedCrossRef
O’Cleirigh, C., Ironson, G., Antoni, M., Fletcher, M. A., McGuffey, L., Balbin, E., et al. (2003). Emotional expression and depth processing: their relation to long-term survival in patients living with HIV/AIDS. Journal of Psychosomatic Research, 54, 225–235. doi: 10.1016/S0022-3999(02)00524-X. PubMedCrossRef
O’Cleirigh, C., Hart, T. A., & James, C. A. (2007b). HIV and anxiety. In M. J. Zvolensky & J. A. J. Smits (Eds.), Health behaviors and physical illness in anxiety and its disorders: Contemporary theory and research. New York: Springer.
Pence, B. W., Miller, W. C., Whetten, K., Eron, J. J., & Gaynes, B. N. (2006). Prevalence of DSM-IV-defined mood, anxiety, and substance use disorders in an HIV clinic in the southeastern United States. Journal of Acquired Immune Deficiency Syndrome, 42, 298–306. doi: 10.1097/01.qai.0000219773.82055.aa. CrossRef
Resnick, H. S., Yehuda, R., Pitman, R. K., & Foy, D. W. (1995). Effect of previous trauma on acute plasma cortisol level following rape. The American Journal of Psychiatry, 152, 1675–1677. PubMed
Sikkema, K. J., Wilson, P. A., Hansen, N. B., Kochman, A., Neufeld, S., Ghebremichael, M. S., et al. (2008). Effects of a coping intervention on transmission risk behavior among people living with HIV/AIDS and a history of childhood sexual abuse. Journal of Acquired Immune Deficiency Syndrome, 47, 506–513. doi: 10.1097/QAI.0b013e318160d727. CrossRef
Spitzer., R. L., Korenke, K., Williams, J. B., for the Patient Health Questionnaire Primary Care Study Group. (1999). Validation and utility of a self-report version of PRIME-MD: The PHQ Primary Care Study. Journal of the American Medical Association, 282, 1737–1744.
Stall, R., Mills, T. C., Williamson, J., Hart, T., Greenwood, G., Paul, J., et al. (2003). Association of co-occurring psychosocial health problems and increased vulnerability to HIV/AIDS among urban men who have sex with men. American Journal of Public Health, 93, 939–942. doi: 10.2105/AJPH.93.6.939. PubMedCrossRef
Trépanier, L. L., Rourke, S. B., Bayoumi, A. M., Halman, M. H., Krzyzanowski, S., & Power, C. (2005). The impact of neuropsychological impairment and depression on health-related quality of life in HIV-infection. Journal of Clinical and Experimental Neuropsychology, 27, 1–15. doi: 10.1080/138033990513546. PubMedCrossRef
van der Kolk, B. A. (1997). The psychobiology of posttraumatic stress disorder. The Journal of Clinical Psychiatry, 58(Suppl 9), 16–24. PubMed
Williams, P., Narciso, L., Browne, G., Roberts, J., Weir, R., & Gafni, A. (2005). The prevalence, correlates, and costs of depression in people living with HIV/AIDS in Ontario: Implications for service directions. AIDS Education and Prevention, 17, 119–130. doi: 10.1521/aeap.22.214.171.124903. PubMedCrossRef
Wu, A., & Quality of Life Subcommittee of the ACTG Outcomes Committee. (1999). ACTG QOL 601-602 (QOL 601-2) Health Survey Manual. AIDS Clinical Trials Group, Available at: https://www.fstrf.org/apps/cfmx/apps/actg/html/QOLForms/manualql601-2799.pdf. Accessed 26 June 2008.
- Functional impairment and health care utilization among HIV-infected men who have sex with men: the relationship with depression and post-traumatic stress
Kenneth H. Mayer
Steven A. Safren
- Springer US