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Gepubliceerd in: Netherlands Heart Journal 12/2022

Open Access 08-09-2022 | Image Puzzle – Answer

Focal myocardial effects in infective endocarditis

Auteurs: V. A. W. M. Umans, Tj. Germans, M. G. J. Duffels

Gepubliceerd in: Netherlands Heart Journal | Uitgave 12/2022

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Given the previously used imaging techniques, we decided to schedule cardiac magnetic resonance imaging (CMR), which showed subendocardial lateral myocardial infarction and foci of myocardial inflammation (Fig. 1). Based on this result, we made the diagnosis of coronary embolisation from endocarditis. This case details two types of myocardial involvement: myocardial ischaemia (embolisation) and interstitial myocarditis (small-vessel vasculitis).
Coronary embolism is a rare complication of infective endocarditis, most prominently originating from large vegetations and infected aortic valves. Large coronary emboli may present as an acute coronary syndrome and are typically seen on coronary angiography as occlusions of the involved coronary artery. Although coronary arteries seem to be protected from embolic involvement, an endocarditis source should be considered [1, 2]. CMR is a sensitive technique to detect cardiac emboli that do not provoke an acute cardiac syndrome [2, 3].
Interstitial myocarditis may originate from seeding of microscopic septic emboli or small-vessel vasculitis [13]. The latter may mimic bacterial endocarditis or be an epiphenomenon. Its presence, however, may have profound therapeutic implications. In case of anti-neutrophilic cytoplasmic autoantibodies–mediated vasculitis, switching to steroid treatment should be considered.
This case shows the importance of multimodality imaging in infective endocarditis with elevated troponin levels. Troponin assessment with subsequent CMR may be pivotal to ascertain coronary embolism as the cause of myocardial involvement. Coronary embolism can result from thrombotic or septal embolism. The macroscopic image of myocarditis resulting from septic seeding or, more rarely, from small-vessel vasculitis is provided by CMR, which is currently the method of choice [2, 3].

Conflict of interest

V.A.W.M. Umans, T. Germans and M.G.J. Duffels declare that they have no competing interests.
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://​creativecommons.​org/​licenses/​by/​4.​0/​.
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Netherlands Heart Journal

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Literatuur
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Metagegevens
Titel
Focal myocardial effects in infective endocarditis
Auteurs
V. A. W. M. Umans
Tj. Germans
M. G. J. Duffels
Publicatiedatum
08-09-2022
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 12/2022
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/s12471-022-01722-7

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