Skip to main content
Top
Gepubliceerd in:

17-02-2021

Comparison of the anxiety, depression and their relationship to quality of life among adult acute leukemia patients and their family caregivers: a cross-sectional study in China

Auteurs: Ying Wang, Jie Yan, JingYi Chen, ChunFeng Wang, YingChun Lin, Yong Wu, Rong Hu

Gepubliceerd in: Quality of Life Research | Uitgave 7/2021

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Purpose

To compare the anxiety, depression and explore their relationship to quality of life (QoL) among adult acute leukemia (AL) patients and family caregivers (FCs) in China.

Methods

A multicenter cross-sectional study was conducted from April 2017 to January 2018. The sample comprised 207 dyads of adult AL patients and FCs. The participants were required to complete socio-demographic information and the Hospital Anxiety and Depression Scale (HADS). The Functional Assessment of Cancer Therapy-Leukemia (FACT-Leu, only for patients) and MOS 36-item Short-Form Health Survey (SF-36, only for FCs) were used to measure QoL.

Results

The mean scores of anxiety and depression for AL patients were 7.89 ± 3.85 and 7.18 ± 4.23, respectively. For FCs, the mean scores of anxiety and depression were 9.96 ± 3.73 and 8.64 ± 3.74. In this study, adult AL Patients’ sex, patients’ depression score, whether patients achieving a CR or not, education, FCs’ depression score, patients’ social/family well-being and emotional well-being were significantly associated with patients’ anxiety or depression (p < 0.05). For FCs, depression was significantly related to the physical component summary (β = 0.127, p = 0.008). There were significant differences in anxiety (t = − 5.92, p < 0.001) and depression (t = − 4.19, p < 0.001) between patients and FCs.

Conclusions

AL patients’ FCs showed higher score of anxiety and depression than that of patients. The psychological health may have a potential relationship between AL patients and their FCs. Healthcare professionals can conduct family-center interventions to improve mental health and QoL of AL patients and FCs.
Bijlagen
Alleen toegankelijk voor geautoriseerde gebruikers
Literatuur
1.
go back to reference Juliusson, G., & Hough, R. (2016). Leukemia. Progress in Tumor Research, 43, 87–100.PubMed Juliusson, G., & Hough, R. (2016). Leukemia. Progress in Tumor Research, 43, 87–100.PubMed
2.
go back to reference Chen, W., Zheng, R., Baade, P. D., Zhang, S., Zeng, H., Bray, F., et al. (2016). Cancer statistics in China, 2015. CA: A Cancer Journal for Clinicians, 66(2), 115–132. Chen, W., Zheng, R., Baade, P. D., Zhang, S., Zeng, H., Bray, F., et al. (2016). Cancer statistics in China, 2015. CA: A Cancer Journal for Clinicians, 66(2), 115–132.
3.
go back to reference Albrecht, T. A. (2014). Physiologic and psychological symptoms experienced by adults with acute leukemia: An integrative literature review. Oncology Nursing Forum, 41(3), 286–295.PubMedPubMedCentral Albrecht, T. A. (2014). Physiologic and psychological symptoms experienced by adults with acute leukemia: An integrative literature review. Oncology Nursing Forum, 41(3), 286–295.PubMedPubMedCentral
4.
go back to reference Wang, J., Shen, N., Zhang, X., Shen, M., Xie, A., Howell, D., et al. (2017). Care burden and its predictive factors in parents of newly diagnosed children with acute lymphoblastic leukemia in academic hospitals in China. Supportive Care in Cancer, 25(12), 3703–3713.PubMed Wang, J., Shen, N., Zhang, X., Shen, M., Xie, A., Howell, D., et al. (2017). Care burden and its predictive factors in parents of newly diagnosed children with acute lymphoblastic leukemia in academic hospitals in China. Supportive Care in Cancer, 25(12), 3703–3713.PubMed
5.
go back to reference Sabine Kayser, R. F. S., Grimwade, D., Yosuico, V. E. D., & Walter, R. B. (2015). Minimal residual disease–directed therapy in acute myeloid leukemia. Blood, 125, 2331–2335.PubMed Sabine Kayser, R. F. S., Grimwade, D., Yosuico, V. E. D., & Walter, R. B. (2015). Minimal residual disease–directed therapy in acute myeloid leukemia. Blood, 125, 2331–2335.PubMed
6.
go back to reference Leak Bryant, A., Walton, A. L., Pergolotti, M., Phillips, B., Bailey, C., Mayer, D. K., et al. (2017). Perceived benefits and barriers to exercise for recently treated adults with acute leukemia. Oncology Nursing Forum, 44(4), 413–420.PubMed Leak Bryant, A., Walton, A. L., Pergolotti, M., Phillips, B., Bailey, C., Mayer, D. K., et al. (2017). Perceived benefits and barriers to exercise for recently treated adults with acute leukemia. Oncology Nursing Forum, 44(4), 413–420.PubMed
7.
go back to reference Meng, Q., Yang, Z., Wu, Y., Xiao, Y., Gu, X., Zhang, M., et al. (2017). Reliability analysis of the Chinese version of the Functional Assessment of Cancer Therapy - Leukemia (FACT-Leu) scale based on multivariate generalizability theory. Health and Quality of Life Outcomes, 15(1), 93.PubMedPubMedCentral Meng, Q., Yang, Z., Wu, Y., Xiao, Y., Gu, X., Zhang, M., et al. (2017). Reliability analysis of the Chinese version of the Functional Assessment of Cancer Therapy - Leukemia (FACT-Leu) scale based on multivariate generalizability theory. Health and Quality of Life Outcomes, 15(1), 93.PubMedPubMedCentral
8.
go back to reference Alexander, G., Bebee, C. E., Chen, K. M., Vignes, R. D., Dixon, B., Escoffery, R., et al. (2016). Burden of caregivers of adult patients with schizophrenia in a predominantly African ancestry population. Quality of Life Research, 25(2), 393–400.PubMed Alexander, G., Bebee, C. E., Chen, K. M., Vignes, R. D., Dixon, B., Escoffery, R., et al. (2016). Burden of caregivers of adult patients with schizophrenia in a predominantly African ancestry population. Quality of Life Research, 25(2), 393–400.PubMed
9.
go back to reference Cella, D., Jensen, S. E., Webster, K., Hongyan, D., Lai, J. S., Rosen, S., et al. (2012). Measuring health-related quality of life in Leukemia: The Functional Assessment of Cancer Therapy—Leukemia (FACT-Leu) Questionnaire. Value in Health, 15(8), 1051–1058.PubMed Cella, D., Jensen, S. E., Webster, K., Hongyan, D., Lai, J. S., Rosen, S., et al. (2012). Measuring health-related quality of life in Leukemia: The Functional Assessment of Cancer Therapy—Leukemia (FACT-Leu) Questionnaire. Value in Health, 15(8), 1051–1058.PubMed
10.
go back to reference Stenberg, U., Ruland, C. M., & Miaskowski, C. (2010). Review of the literature on the effects of caring for a patient with cancer. Psychooncology, 19(10), 1013–1025.PubMed Stenberg, U., Ruland, C. M., & Miaskowski, C. (2010). Review of the literature on the effects of caring for a patient with cancer. Psychooncology, 19(10), 1013–1025.PubMed
11.
go back to reference Wang, C., Yan, J., Chen, J., Wang, Y., Lin, Y. C., Hu, R., et al. (2020). Factors associated with quality of life of adult patients with acute leukemia and their family caregivers in China: A cross-sectional study. Health and Quality of Life Outcomes, 18(1), 8.PubMedPubMedCentral Wang, C., Yan, J., Chen, J., Wang, Y., Lin, Y. C., Hu, R., et al. (2020). Factors associated with quality of life of adult patients with acute leukemia and their family caregivers in China: A cross-sectional study. Health and Quality of Life Outcomes, 18(1), 8.PubMedPubMedCentral
12.
go back to reference Beck, K. R., Tan, S. M., Lum, S. S., Lim, L. E., & Krishna, L. K. (2016). Validation of the emotion thermometers and hospital anxiety and depression scales in Singapore: Screening cancer patients for distress, anxiety and depression. Asia-Pacific Journal of Clinical Oncology, 12(2), e241–e249.PubMed Beck, K. R., Tan, S. M., Lum, S. S., Lim, L. E., & Krishna, L. K. (2016). Validation of the emotion thermometers and hospital anxiety and depression scales in Singapore: Screening cancer patients for distress, anxiety and depression. Asia-Pacific Journal of Clinical Oncology, 12(2), e241–e249.PubMed
13.
go back to reference Romito, F., Goldzweig, G., Cormio, C., Hagedoorn, M., & Andersen, B. L. (2013). Informal caregiving for cancer patients. Cancer, 119(Suppl 11), 2160–2169.PubMed Romito, F., Goldzweig, G., Cormio, C., Hagedoorn, M., & Andersen, B. L. (2013). Informal caregiving for cancer patients. Cancer, 119(Suppl 11), 2160–2169.PubMed
14.
go back to reference Northouse, L., Williams, A. L., Given, B., & McCorkle, R. (2012). Psychosocial care for family caregivers of patients with cancer. Journal of Clinical Oncology, 30(11), 1227–1234.PubMed Northouse, L., Williams, A. L., Given, B., & McCorkle, R. (2012). Psychosocial care for family caregivers of patients with cancer. Journal of Clinical Oncology, 30(11), 1227–1234.PubMed
15.
go back to reference Kim, Y., Kashy, D. A., Wellisch, D. K., Spillers, R. L., & Smith, T. G. (2008). Quality of life of couples dealing with cancer: Dyadic and individual adjustment among breast and prostate cancer survivors and their spousal caregivers. Annals of Behavioral Medicine, 35, 230.PubMed Kim, Y., Kashy, D. A., Wellisch, D. K., Spillers, R. L., & Smith, T. G. (2008). Quality of life of couples dealing with cancer: Dyadic and individual adjustment among breast and prostate cancer survivors and their spousal caregivers. Annals of Behavioral Medicine, 35, 230.PubMed
16.
go back to reference Dellafiore, F., Chung, M. L., Alvaro, R., Durante, A., Colaceci, S., Vellone, E., et al. (2019). The association between mutuality, anxiety, and depression in heart failure patient-caregiver dyads: An actor-partner interdependence model analysis. Journal of Cardiovascular Nursing, 34(6), 465–473. Dellafiore, F., Chung, M. L., Alvaro, R., Durante, A., Colaceci, S., Vellone, E., et al. (2019). The association between mutuality, anxiety, and depression in heart failure patient-caregiver dyads: An actor-partner interdependence model analysis. Journal of Cardiovascular Nursing, 34(6), 465–473.
17.
go back to reference Chung, M. L., Moser, D. K., Lennie, T. A., & Rayens, M. K. (2009). The effects of depressive symptoms and anxiety on quality of life in patients with heart failure and their spouses: Testing dyadic dynamics using actor-partner interdependence model. Journal of psychosomatic research, 67(1), 29.PubMedPubMedCentral Chung, M. L., Moser, D. K., Lennie, T. A., & Rayens, M. K. (2009). The effects of depressive symptoms and anxiety on quality of life in patients with heart failure and their spouses: Testing dyadic dynamics using actor-partner interdependence model. Journal of psychosomatic research, 67(1), 29.PubMedPubMedCentral
18.
go back to reference Wan-Fei, K., Syed Hassan, S. T., Munn Sann, L., Fadhilah Ismail, S. I., Abdul Raman, R., & Ibrahim, F. (2017). Depression, anxiety and quality of life in stroke survivors and their family caregivers: A pilot study using an actor/partner interdependence model. Electronic Physician, 9(8), 4924–4933.PubMedPubMedCentral Wan-Fei, K., Syed Hassan, S. T., Munn Sann, L., Fadhilah Ismail, S. I., Abdul Raman, R., & Ibrahim, F. (2017). Depression, anxiety and quality of life in stroke survivors and their family caregivers: A pilot study using an actor/partner interdependence model. Electronic Physician, 9(8), 4924–4933.PubMedPubMedCentral
19.
go back to reference Monika, J. R., Kerenaftali, K., O’Connell, D. L., Helen, G., David, G., Merrett, N. D., et al. (2017). Anxiety, depression and quality of life in chronic obstructive pulmonary disease patients and caregivers an actor-partner interdependence model analysis. Quality of Life Research, 28, 461. Monika, J. R., Kerenaftali, K., O’Connell, D. L., Helen, G., David, G., Merrett, N. D., et al. (2017). Anxiety, depression and quality of life in chronic obstructive pulmonary disease patients and caregivers an actor-partner interdependence model analysis. Quality of Life Research, 28, 461.
20.
go back to reference Nyamathi, A. (2010). Comprehensive health seeking and coping paradigm. Journal of Advanced Nursing., 14(4), 281–290. Nyamathi, A. (2010). Comprehensive health seeking and coping paradigm. Journal of Advanced Nursing., 14(4), 281–290.
21.
go back to reference Saria, M. G., Courchesne, N. S., Evangelista, L., Carter, J. L., MacManus, D. A., Gorman, M. K., et al. (2017). Anxiety and depression associated with burden in caregivers of patients with brain metastases. Oncology Nursing Forum, 44(3), 306–315.PubMed Saria, M. G., Courchesne, N. S., Evangelista, L., Carter, J. L., MacManus, D. A., Gorman, M. K., et al. (2017). Anxiety and depression associated with burden in caregivers of patients with brain metastases. Oncology Nursing Forum, 44(3), 306–315.PubMed
22.
go back to reference Ingvar Bjelland, A. A. D., Haug, T. T., & Neckelmann, D. (2002). The validity of the Hospital Anxiety and Depression Scale An updated literature review. Journal of Psychosomatic Research, 52, 69–77.PubMed Ingvar Bjelland, A. A. D., Haug, T. T., & Neckelmann, D. (2002). The validity of the Hospital Anxiety and Depression Scale An updated literature review. Journal of Psychosomatic Research, 52, 69–77.PubMed
23.
go back to reference Lee, Y. H., Liao, Y. C., Liao, W. Y., Shun, S. C., Liu, Y. C., Chan, J. C., et al. (2013). Anxiety, depression and related factors in family caregivers of newly diagnosed lung cancer patients before first treatment. Psychooncology, 22(11), 2617–2623.PubMed Lee, Y. H., Liao, Y. C., Liao, W. Y., Shun, S. C., Liu, Y. C., Chan, J. C., et al. (2013). Anxiety, depression and related factors in family caregivers of newly diagnosed lung cancer patients before first treatment. Psychooncology, 22(11), 2617–2623.PubMed
24.
go back to reference Hartung, T. J., Friedrich, M., Johansen, C., Wittchen, H. U., Faller, H., Koch, U., et al. (2017). The Hospital Anxiety and Depression Scale (HADS) and the 9-item Patient Health Questionnaire (PHQ-9) as screening instruments for depression in patients with cancer. Cancer, 123(21), 4236–4243.PubMed Hartung, T. J., Friedrich, M., Johansen, C., Wittchen, H. U., Faller, H., Koch, U., et al. (2017). The Hospital Anxiety and Depression Scale (HADS) and the 9-item Patient Health Questionnaire (PHQ-9) as screening instruments for depression in patients with cancer. Cancer, 123(21), 4236–4243.PubMed
25.
go back to reference Temiz, G., & Durna, Z. (2019). Evaluation of quality of life and health care needs in cancer patients receiving chemotherapy. Journal of Cancer Education, 35, 796. Temiz, G., & Durna, Z. (2019). Evaluation of quality of life and health care needs in cancer patients receiving chemotherapy. Journal of Cancer Education, 35, 796.
26.
go back to reference Lam, C. L., Tse, E. Y., Gandek, B., & Fong, D. Y. (2005). The SF-36 summary scales were valid, reliable, and equivalent in a Chinese population. Journal of Clinical Epidemiology, 58(8), 815–822.PubMed Lam, C. L., Tse, E. Y., Gandek, B., & Fong, D. Y. (2005). The SF-36 summary scales were valid, reliable, and equivalent in a Chinese population. Journal of Clinical Epidemiology, 58(8), 815–822.PubMed
27.
go back to reference Ho, R. C. M., Fu, E. H. Y., Chua, A. N. C., Cheak, A. A. C., & Mak, A. (2011). Clinical and psychosocial factors associated with depression and anxiety in Singaporean patients with rheumatoid arthritis. International Journal of Rheumatic Diseases, 14(1), 37–47.PubMed Ho, R. C. M., Fu, E. H. Y., Chua, A. N. C., Cheak, A. A. C., & Mak, A. (2011). Clinical and psychosocial factors associated with depression and anxiety in Singaporean patients with rheumatoid arthritis. International Journal of Rheumatic Diseases, 14(1), 37–47.PubMed
28.
go back to reference Ho, R. C. M., Giam, Y., Ng, T. P., Mak, A., Goh, D., Zhang, M. W. B., et al. (2010). The influence of childhood atopic dermatitis on health of mothers, and its impact on Asian families. Pediatric Allergy & Immunology, 21(3), 501–507. Ho, R. C. M., Giam, Y., Ng, T. P., Mak, A., Goh, D., Zhang, M. W. B., et al. (2010). The influence of childhood atopic dermatitis on health of mothers, and its impact on Asian families. Pediatric Allergy & Immunology, 21(3), 501–507.
29.
go back to reference Xie, H., Cheng, C., Tao, Y., Zhang, J., Robert, D., Jia, J., et al. (2016). Quality of life in Chinese family caregivers for elderly people with chronic diseases. Health and Quality of Life Outcomes, 14(1), 99.PubMedPubMedCentral Xie, H., Cheng, C., Tao, Y., Zhang, J., Robert, D., Jia, J., et al. (2016). Quality of life in Chinese family caregivers for elderly people with chronic diseases. Health and Quality of Life Outcomes, 14(1), 99.PubMedPubMedCentral
30.
go back to reference Pereira, M. G., Vilaca, M., Pereira, M., Ferreira, G., Monteiro, S., Coelho, H., et al. (2020). The mediator role of unmet needs on quality of life in myeloma patients. Quality of Life Research, 29(10), 2641–2650.PubMed Pereira, M. G., Vilaca, M., Pereira, M., Ferreira, G., Monteiro, S., Coelho, H., et al. (2020). The mediator role of unmet needs on quality of life in myeloma patients. Quality of Life Research, 29(10), 2641–2650.PubMed
31.
go back to reference Smith, A. B., Selby, P. J., Velikova, G., Stark, D., Wright, E. P., Gould, A., & Cull, A. (2002). Factor analysis of the Hospital Anxiety and Depression Scale from a large cancer population. Psychology and Psychotherapy, 75, 165–1761.PubMed Smith, A. B., Selby, P. J., Velikova, G., Stark, D., Wright, E. P., Gould, A., & Cull, A. (2002). Factor analysis of the Hospital Anxiety and Depression Scale from a large cancer population. Psychology and Psychotherapy, 75, 165–1761.PubMed
32.
go back to reference Rodin, G., Deckert, A., Tong, E., Le, L. W., Rydall, A., Schimmer, A., et al. (2018). Traumatic stress in patients with acute leukemia: A prospective cohort study. Psychooncology, 27(2), 515–523.PubMed Rodin, G., Deckert, A., Tong, E., Le, L. W., Rydall, A., Schimmer, A., et al. (2018). Traumatic stress in patients with acute leukemia: A prospective cohort study. Psychooncology, 27(2), 515–523.PubMed
33.
go back to reference Janda, M., Neale, R. E., Klein, K., O’Connell, D. L., Gooden, H., Goldstein, D., et al. (2017). Anxiety, depression and quality of life in people with pancreatic cancer and their carers. Pancreatology, 17(2), 321–327.PubMed Janda, M., Neale, R. E., Klein, K., O’Connell, D. L., Gooden, H., Goldstein, D., et al. (2017). Anxiety, depression and quality of life in people with pancreatic cancer and their carers. Pancreatology, 17(2), 321–327.PubMed
34.
go back to reference Jeong, A., Shin, D. W., Kim, S. Y., Yang, H. K., & Park, J. H. (2016). Avoidance of cancer communication, perceived social support, and anxiety and depression among patients with cancer. Psychooncology., 25(11), 1301–1307.PubMed Jeong, A., Shin, D. W., Kim, S. Y., Yang, H. K., & Park, J. H. (2016). Avoidance of cancer communication, perceived social support, and anxiety and depression among patients with cancer. Psychooncology., 25(11), 1301–1307.PubMed
35.
go back to reference Ivziku, D., Clari, M., Piredda, M., De Marinis, M. G., & Matarese, M. (2019). Anxiety, depression and quality of life in chronic obstructive pulmonary disease patients and caregivers: An actor-partner interdependence model analysis. Quality of Life Research, 28(2), 461–472.PubMed Ivziku, D., Clari, M., Piredda, M., De Marinis, M. G., & Matarese, M. (2019). Anxiety, depression and quality of life in chronic obstructive pulmonary disease patients and caregivers: An actor-partner interdependence model analysis. Quality of Life Research, 28(2), 461–472.PubMed
36.
go back to reference Kim, Y., Carver, C. S., Spillers, R. L., Crammer, C., & Zhou, E. S. (2011). Individual and dyadic relations between spiritual well-being and quality of life among cancer survivors and their spousal caregivers. Psychooncology, 20(7), 762–770.PubMed Kim, Y., Carver, C. S., Spillers, R. L., Crammer, C., & Zhou, E. S. (2011). Individual and dyadic relations between spiritual well-being and quality of life among cancer survivors and their spousal caregivers. Psychooncology, 20(7), 762–770.PubMed
37.
go back to reference Gough, K., & Hudson, P. (2009). Psychometric properties of the Hospital Anxiety and Depression Scale in family caregivers of palliative care patients. Journal of Pain and Symptom Management, 37(5), 797–806.PubMed Gough, K., & Hudson, P. (2009). Psychometric properties of the Hospital Anxiety and Depression Scale in family caregivers of palliative care patients. Journal of Pain and Symptom Management, 37(5), 797–806.PubMed
38.
go back to reference Shin, J. Y., Lim, J. W., Shin, D. W., Kim, S. Y., Yang, H. K., Cho, J., et al. (2017). Underestimated caregiver burden by cancer patients and its association with quality of life, depression and anxiety among caregivers. The European Journal of Cancer Care, 27, e12814. Shin, J. Y., Lim, J. W., Shin, D. W., Kim, S. Y., Yang, H. K., Cho, J., et al. (2017). Underestimated caregiver burden by cancer patients and its association with quality of life, depression and anxiety among caregivers. The European Journal of Cancer Care, 27, e12814.
39.
go back to reference Lin, C. R., Chen, S. C., Simard, S., Chang, T. C., & Lai, Y. H. (2018). Psychometric testing of the fear of cancer recurrence inventory- caregiver chinese version in cancer family caregivers in Taiwan. Psycho-Oncology, 27, 1580.PubMed Lin, C. R., Chen, S. C., Simard, S., Chang, T. C., & Lai, Y. H. (2018). Psychometric testing of the fear of cancer recurrence inventory- caregiver chinese version in cancer family caregivers in Taiwan. Psycho-Oncology, 27, 1580.PubMed
40.
go back to reference Kim, Y., Van Ryn, M., Rowland, J., et al. (2015). Effects of gender and depressive symptoms on quality of life among colorectal and lung cancer patients and their family caregivers. Psycho Oncology, 24, 95.PubMed Kim, Y., Van Ryn, M., Rowland, J., et al. (2015). Effects of gender and depressive symptoms on quality of life among colorectal and lung cancer patients and their family caregivers. Psycho Oncology, 24, 95.PubMed
41.
go back to reference Segrin, C., Badger, T. A., & Harrington, J. (2012). Interdependent psychological quality of life in dyads adjusting to prostate cancer. Health Psychology Official Journal of the Division of Health Psychology American Psychological Association, 31(1), 70–79. Segrin, C., Badger, T. A., & Harrington, J. (2012). Interdependent psychological quality of life in dyads adjusting to prostate cancer. Health Psychology Official Journal of the Division of Health Psychology American Psychological Association, 31(1), 70–79.
42.
go back to reference Girgis, A., & Lambert, S. (2009). Caregivers of cancer survivors: The state of the field | NOVA. The University of Newcastle’s Digital Repository. Construction & Building Materials, 23(6), 2196–2206. Girgis, A., & Lambert, S. (2009). Caregivers of cancer survivors: The state of the field | NOVA. The University of Newcastle’s Digital Repository. Construction & Building Materials, 23(6), 2196–2206.
43.
go back to reference Li, Q., Lin, Y., Qiu, Y., Gao, B., & Xu, Y. (2014). The assessment of health-related quality of life and related factors in Chinese elderly patients undergoing chemotherapy for advanced cancer: A cross-sectional study. European Journal of Oncology Nursing the Official Journal of European Oncology Nursing Society, 18(4), 425–435.PubMed Li, Q., Lin, Y., Qiu, Y., Gao, B., & Xu, Y. (2014). The assessment of health-related quality of life and related factors in Chinese elderly patients undergoing chemotherapy for advanced cancer: A cross-sectional study. European Journal of Oncology Nursing the Official Journal of European Oncology Nursing Society, 18(4), 425–435.PubMed
45.
go back to reference Friðriksdóttir, N., Sævarsdóttir, Þ, Halfdanardottir, S. I., Jonsdottir, A., Magnúsdóttir, H., Olafsdottir, K. L., et al. (2011). Family members of cancer patients: Needs, quality of life and symptoms of anxiety and depression. Acta Oncologica, 50, 250. Friðriksdóttir, N., Sævarsdóttir, Þ, Halfdanardottir, S. I., Jonsdottir, A., Magnúsdóttir, H., Olafsdottir, K. L., et al. (2011). Family members of cancer patients: Needs, quality of life and symptoms of anxiety and depression. Acta Oncologica, 50, 250.
46.
go back to reference Joseph, R. W., Liu, F. X., Shillington, A. C., Macahilig, C. P., Diede, S. J., Dave, V., et al. (2020). Health-related quality of life (QoL) in patients with advanced melanoma receiving immunotherapies in real-world clinical practice settings. Quality of Life Research, 29(10), 2651–2660.PubMedPubMedCentral Joseph, R. W., Liu, F. X., Shillington, A. C., Macahilig, C. P., Diede, S. J., Dave, V., et al. (2020). Health-related quality of life (QoL) in patients with advanced melanoma receiving immunotherapies in real-world clinical practice settings. Quality of Life Research, 29(10), 2651–2660.PubMedPubMedCentral
47.
go back to reference Linden, W., Vodermaier, A., Mackenzie, R., & Greig, D. (2012). Anxiety and depression after cancer diagnosis: Prevalence rates by cancer type, gender, and age. Journal of Affective Disorders, 141(2–3), 343–351.PubMed Linden, W., Vodermaier, A., Mackenzie, R., & Greig, D. (2012). Anxiety and depression after cancer diagnosis: Prevalence rates by cancer type, gender, and age. Journal of Affective Disorders, 141(2–3), 343–351.PubMed
48.
go back to reference Hinz, A., Herzberg, P. Y., Lordick, F., Weis, J., & Mehnert, A. (2019). Age and gender differences in anxiety and depression in cancer patients compared with the general population. European Journal of Cancer Care, 28(7), e13129.PubMed Hinz, A., Herzberg, P. Y., Lordick, F., Weis, J., & Mehnert, A. (2019). Age and gender differences in anxiety and depression in cancer patients compared with the general population. European Journal of Cancer Care, 28(7), e13129.PubMed
49.
go back to reference Cardoso, G., Graca, J., Klut, C., Trancas, B., & Papoila, A. (2016). Depression and anxiety symptoms following cancer diagnosis: A cross-sectional study. Psychology, Health & Medicine, 21(5), 562–570. Cardoso, G., Graca, J., Klut, C., Trancas, B., & Papoila, A. (2016). Depression and anxiety symptoms following cancer diagnosis: A cross-sectional study. Psychology, Health & Medicine, 21(5), 562–570.
50.
go back to reference Ding, T., Wang, X., Fu, A., Xu, L., & Lin, J. (2019). Anxiety and depression predict unfavorable survival in acute myeloid leukemia patients. Medicine (Baltimore), 98(43), e17314. Ding, T., Wang, X., Fu, A., Xu, L., & Lin, J. (2019). Anxiety and depression predict unfavorable survival in acute myeloid leukemia patients. Medicine (Baltimore), 98(43), e17314.
51.
go back to reference Gu, M., Hao, X., Cong, L., & Sun, J. (2019). The prevalence, risk factors, and prognostic value of anxiety and depression in refractory or relapsed acute myeloid leukemia patients of North China. Medicine (Baltimore), 98(50), e18196. Gu, M., Hao, X., Cong, L., & Sun, J. (2019). The prevalence, risk factors, and prognostic value of anxiety and depression in refractory or relapsed acute myeloid leukemia patients of North China. Medicine (Baltimore), 98(50), e18196.
52.
go back to reference Isidori, A., Loscocco, F., & Visani, G. (2016). AML therapy in the elderly: A time for a change. Expert Opinion on Drug Safety, 15(7), 891–892.PubMed Isidori, A., Loscocco, F., & Visani, G. (2016). AML therapy in the elderly: A time for a change. Expert Opinion on Drug Safety, 15(7), 891–892.PubMed
Metagegevens
Titel
Comparison of the anxiety, depression and their relationship to quality of life among adult acute leukemia patients and their family caregivers: a cross-sectional study in China
Auteurs
Ying Wang
Jie Yan
JingYi Chen
ChunFeng Wang
YingChun Lin
Yong Wu
Rong Hu
Publicatiedatum
17-02-2021
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 7/2021
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-021-02785-6