Skip to main content
Top
Gepubliceerd in: Quality of Life Research 7/2021

26-04-2021

The association between diabetic complications and health-related quality of life in patients with type 2 diabetes: a cross-sectional study from Iran

Auteurs: Hassan Karami, Maryam Shirvani Shiri, Aziz Rezapour, Ranaa Sarvari Mehrabadi, Somayeh Afshari

Gepubliceerd in: Quality of Life Research | Uitgave 7/2021

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Introduction

This study aimed to investigate the health-related quality of life (HRQoL) of type 2 diabetic patients and its relationship with the complications of diabetes in Farashband County, Fars, Iran.

Methods

Data of this cross-sectional study were collected by a researcher-made demographic questionnaire, EuroQol-5 Dimensions questionnaire (EQ-5D) and Visual Analog Scale (VAS) and also from patient records. Multivariate regression model was used to investigate the net effect of diabetes complications on HRQoL after controlling for other independent variables.

Results

A total of 685 patients with a mean age of 58.36 and a disease duration of 7.64 years participated in the study. The mean EQ-5D and EQ-VAS scores of all patients were 0.64 and 56.53, respectively. The HRQoL dimensions in which the largest portions of the population had problems were Pain/Discomfort (77.23%) and Anxiety/Depression (63.50%). Among the studied diabetic patients, women, divorcees, and widows were more likely to report problems in all dimensions of HRQoL, and people without complications, people with university degrees, and employed people were more likely to report fewer problems in these dimensions (P < 0.05). After controlling for the effect of all independent variables in the multivariate regression model, a significant negative relationship was found between diabetes complications and EQ-5D: β =  − 0.149 (95% CI − 0.186, − 0.112) and EQ-VAS: β =  − 6.697 (95% CI − 9.947, − 3.747). This indicates that for each additional diabetic complication, 0.149 and 6.697 units of EQ-5D Index and EQ-VAS were reduced, respectively.

Conclusion

This study indicated that type 2 diabetic patients in the studied region, especially those with complications, suffer from poor HRQoL. Therefore, more attention should be paid to the main determinants of HRQoL when adopting policies for diabetes management in order to ultimately improve the HRQoL of these patients.
Literatuur
2.
go back to reference Moradi, Y., Baradaran, H. R., Djalalinia, S., Chinekesh, A., Khamseh, M. E., Dastoorpoor, M., et al. (2019). Complications of type 2 diabetes in Iranian population: An updated systematic review and meta-analysis. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13(3), 2300–2312.CrossRef Moradi, Y., Baradaran, H. R., Djalalinia, S., Chinekesh, A., Khamseh, M. E., Dastoorpoor, M., et al. (2019). Complications of type 2 diabetes in Iranian population: An updated systematic review and meta-analysis. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13(3), 2300–2312.CrossRef
5.
go back to reference Gu, S., Wang, X., Shi, L., Sun, Q., Hu, X., Gu, Y., et al. (2020). Health-related quality of life of type 2 diabetes patients hospitalized for a diabetes-related complication. Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. Gu, S., Wang, X., Shi, L., Sun, Q., Hu, X., Gu, Y., et al. (2020). Health-related quality of life of type 2 diabetes patients hospitalized for a diabetes-related complication. Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation.
8.
go back to reference Gomes, A. R., & Santos, L. (2017). Prevalência das complicações da diabetes mellitus no ACeS Santo Tirso/Trofa: estudodescritivo. Revista Portuguesa de MedicinaGeral e Familiar, 33(4), 252–260. Gomes, A. R., & Santos, L. (2017). Prevalência das complicações da diabetes mellitus no ACeS Santo Tirso/Trofa: estudodescritivo. Revista Portuguesa de MedicinaGeral e Familiar, 33(4), 252–260.
9.
go back to reference Deshpande, A. D., Harris-Hayes, M., & Schootman, M. (2008). Epidemiology of diabetes and diabetes-related complications. Physical Therapy, 88(11), 1254–1264.CrossRef Deshpande, A. D., Harris-Hayes, M., & Schootman, M. (2008). Epidemiology of diabetes and diabetes-related complications. Physical Therapy, 88(11), 1254–1264.CrossRef
11.
go back to reference Jiao, F., Wong, C. K. H., Gangwani, R., Tan, K. C. B., Tang, S. C. W., & Lam, C. L. K. (2017). Health-related quality of life and health preference of Chinese patients with diabetes mellitus managed in primary care and secondary care setting: Decrements associated with individual complication and number of complications. Health and Quality of Life Outcomes, 15(1), 125.CrossRef Jiao, F., Wong, C. K. H., Gangwani, R., Tan, K. C. B., Tang, S. C. W., & Lam, C. L. K. (2017). Health-related quality of life and health preference of Chinese patients with diabetes mellitus managed in primary care and secondary care setting: Decrements associated with individual complication and number of complications. Health and Quality of Life Outcomes, 15(1), 125.CrossRef
13.
go back to reference Luk, A., Zhang, Y., Ko, G., Brown, N., Ozaki, R., Tong, P., et al. (2014). Health-related quality of life in Chinese patients with type 2 diabetes: An analysis of the Joint Asia Diabetes Evaluation (JADE) Program. Journal of Diabetes Metabolism, 5(333), 2. Luk, A., Zhang, Y., Ko, G., Brown, N., Ozaki, R., Tong, P., et al. (2014). Health-related quality of life in Chinese patients with type 2 diabetes: An analysis of the Joint Asia Diabetes Evaluation (JADE) Program. Journal of Diabetes Metabolism, 5(333), 2.
14.
go back to reference Mohtasham-Amiri, Z., Barzigar, A., Kolamroudi, H. R., Hoseini, S., Rezvani, S., Shakib, R. J., et al. (2015). Prevalence, awareness and control of diabetes in urban area of north of Iran, 2009. International Journal of Diabetes in Developing Countries, 35(3), 346–350.CrossRef Mohtasham-Amiri, Z., Barzigar, A., Kolamroudi, H. R., Hoseini, S., Rezvani, S., Shakib, R. J., et al. (2015). Prevalence, awareness and control of diabetes in urban area of north of Iran, 2009. International Journal of Diabetes in Developing Countries, 35(3), 346–350.CrossRef
15.
go back to reference Katibeh, M., Hosseini, S., Soleimanizad, R., Manaviat, M., Kheiri, B., Khabazkhoob, M., et al. (2015). Prevalence and risk factors of diabetes mellitus in a central district in Islamic Republic of Iran: A population-based study on adults aged 40–80 years. EMHJ-Eastern Mediterranean Health Journal, 21(6), 412–419. Katibeh, M., Hosseini, S., Soleimanizad, R., Manaviat, M., Kheiri, B., Khabazkhoob, M., et al. (2015). Prevalence and risk factors of diabetes mellitus in a central district in Islamic Republic of Iran: A population-based study on adults aged 40–80 years. EMHJ-Eastern Mediterranean Health Journal, 21(6), 412–419.
16.
go back to reference Janghorbani, M., & Amini, M. (2004). Cataract in type 2 diabetes mellitus in Isfahan, Iran: Incidence and risk factors. Ophthalmic Epidemiology, 11(5), 347–358.CrossRef Janghorbani, M., & Amini, M. (2004). Cataract in type 2 diabetes mellitus in Isfahan, Iran: Incidence and risk factors. Ophthalmic Epidemiology, 11(5), 347–358.CrossRef
18.
go back to reference Amini, M., Safaei, H., & Aminorroaya, A. (2007). The incidence of microalbuminuria and its associated risk factors in type 2 diabetic patients in Isfahan, Iran. The Review of Diabetic Studies: RDS, 4(4), 242.CrossRef Amini, M., Safaei, H., & Aminorroaya, A. (2007). The incidence of microalbuminuria and its associated risk factors in type 2 diabetic patients in Isfahan, Iran. The Review of Diabetic Studies: RDS, 4(4), 242.CrossRef
19.
go back to reference Zakerkish, M., Shahbazian, H. B., Shahbazian, H., Mahmoud Latifi, S., & Moravej Aleali, A. (2013). Albuminuria and its correlates in type 2 diabetic patients. Iranian Journal of Kidney Diseases, 7(4). Zakerkish, M., Shahbazian, H. B., Shahbazian, H., Mahmoud Latifi, S., & Moravej Aleali, A. (2013). Albuminuria and its correlates in type 2 diabetic patients. Iranian Journal of Kidney Diseases, 7(4).
21.
go back to reference Baygi, M. Z., Seyedin, H., Salehi, M., & Sirizi, M. J. (2015). Structural and contextual dimensions of Iranian primary health care system at local level. Iranian Red Crescent Medical Journal, 17(1), e17222. Baygi, M. Z., Seyedin, H., Salehi, M., & Sirizi, M. J. (2015). Structural and contextual dimensions of Iranian primary health care system at local level. Iranian Red Crescent Medical Journal, 17(1), e17222.
22.
go back to reference Majdzadeh, R. (2012). Family physician implementation and preventive medicine; opportunities and challenges. International Journal of Preventive Medicine, 3(10), 665.PubMedPubMedCentral Majdzadeh, R. (2012). Family physician implementation and preventive medicine; opportunities and challenges. International Journal of Preventive Medicine, 3(10), 665.PubMedPubMedCentral
25.
go back to reference Goudarzi, R., Sari, A. A., Zeraati, H., Rashidian, A., Mohammad, K., & Amini, S. (2019). Valuation of quality weights for EuroQol 5-dimensional health states with the time trade-off method in the Capital of Iran. Value in Health Regional Issues, 18, 170–175.CrossRef Goudarzi, R., Sari, A. A., Zeraati, H., Rashidian, A., Mohammad, K., & Amini, S. (2019). Valuation of quality weights for EuroQol 5-dimensional health states with the time trade-off method in the Capital of Iran. Value in Health Regional Issues, 18, 170–175.CrossRef
26.
go back to reference Zare, F., Ameri, H., Madadizadeh, F., & Aghaei, M. R. (2021). Validity and reliability of the EQ-5D-3L (a generic preference-based instrument used for calculating quality-adjusted life -years) for patients with type 2 diabetes in Iran. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. https://doi.org/10.1016/j.dsx.2021.01.009CrossRef Zare, F., Ameri, H., Madadizadeh, F., & Aghaei, M. R. (2021). Validity and reliability of the EQ-5D-3L (a generic preference-based instrument used for calculating quality-adjusted life -years) for patients with type 2 diabetes in Iran. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. https://​doi.​org/​10.​1016/​j.​dsx.​2021.​01.​009CrossRef
28.
go back to reference Cohen, J., Cohen, P., West, S. G., & Aiken, L. S. (2013). Applied multiple regression/correlation analysis for the behavioral sciences. Routledge.CrossRef Cohen, J., Cohen, P., West, S. G., & Aiken, L. S. (2013). Applied multiple regression/correlation analysis for the behavioral sciences. Routledge.CrossRef
33.
go back to reference Lee, W. J., Song, K.-H., Noh, J. H., Choi, Y. J., & Jo, M.-W. (2012). Health-related quality of life using the EuroQol 5D questionnaire in Korean patients with type 2 diabetes. Journal of Korean Medical Science, 27(3), 255–260.CrossRef Lee, W. J., Song, K.-H., Noh, J. H., Choi, Y. J., & Jo, M.-W. (2012). Health-related quality of life using the EuroQol 5D questionnaire in Korean patients with type 2 diabetes. Journal of Korean Medical Science, 27(3), 255–260.CrossRef
34.
go back to reference Arifin, B., Idrus, L. R., van Asselt, A. D., Purba, F. D., Perwitasari, D. A., Thobari, J. A., et al. (2019). Health-related quality of life in Indonesian type 2 diabetes mellitus outpatients measured with the Bahasa version of EQ-5D. Quality of Life Research, 28(5), 1179–1190.CrossRef Arifin, B., Idrus, L. R., van Asselt, A. D., Purba, F. D., Perwitasari, D. A., Thobari, J. A., et al. (2019). Health-related quality of life in Indonesian type 2 diabetes mellitus outpatients measured with the Bahasa version of EQ-5D. Quality of Life Research, 28(5), 1179–1190.CrossRef
35.
go back to reference Holmes, J., McGill, S., Kind, P., Bottomley, J., Gillam, S., & Murphy, M. (2000). Health-related quality of life in type 2 diabetes (T2ARDIS-2). Value in Health, 3, S47–S51.CrossRef Holmes, J., McGill, S., Kind, P., Bottomley, J., Gillam, S., & Murphy, M. (2000). Health-related quality of life in type 2 diabetes (T2ARDIS-2). Value in Health, 3, S47–S51.CrossRef
37.
go back to reference Sakamaki, H., Ikeda, S., Ikegami, N., Uchigata, Y., Iwamoto, Y., Origasa, H., et al. (2006). Measurement of HRQL using EQ-5D in patients with type 2 diabetes mellitus in Japan. Value in Health, 9(1), 47–53.CrossRef Sakamaki, H., Ikeda, S., Ikegami, N., Uchigata, Y., Iwamoto, Y., Origasa, H., et al. (2006). Measurement of HRQL using EQ-5D in patients with type 2 diabetes mellitus in Japan. Value in Health, 9(1), 47–53.CrossRef
38.
go back to reference Saadatjoo, S. A., Rezvanee, M. R., Tabyee, S. H., & Oudi, D. (2012). Life quality comparison in type 2 diabetic patients and none diabetic persons. Modern Care Journal, 9(1). Saadatjoo, S. A., Rezvanee, M. R., Tabyee, S. H., & Oudi, D. (2012). Life quality comparison in type 2 diabetic patients and none diabetic persons. Modern Care Journal, 9(1).
39.
go back to reference Ahmadi, A., Hasanzadeh, J., RahimiMadiseh, M., & Lashkari, L. (2011). Effective factors in the quality of life in patients with type 2 diabetes in Chaharmahal & Bakhteyari Province. Journal of North Khorasan University of Medical Sciences, 3(17), 2011. Ahmadi, A., Hasanzadeh, J., RahimiMadiseh, M., & Lashkari, L. (2011). Effective factors in the quality of life in patients with type 2 diabetes in Chaharmahal & Bakhteyari Province. Journal of North Khorasan University of Medical Sciences, 3(17), 2011.
42.
go back to reference Zhang, Y., Wu, J., Chen, Y., & Shi, L. (2020). EQ-5D-3L Decrements by Diabetes Complications and Comorbidities in China. Diabetes Therapy, 1–12. Zhang, Y., Wu, J., Chen, Y., & Shi, L. (2020). EQ-5D-3L Decrements by Diabetes Complications and Comorbidities in China. Diabetes Therapy, 1–12.
43.
go back to reference Mukuria, C., & Brazier, J. (2013). Valuing the EQ-5D and the SF-6D health states using subjective well-being: A secondary analysis of patient data. Social Science & Medicine, 77, 97–105.CrossRef Mukuria, C., & Brazier, J. (2013). Valuing the EQ-5D and the SF-6D health states using subjective well-being: A secondary analysis of patient data. Social Science & Medicine, 77, 97–105.CrossRef
44.
go back to reference Ostovaneh, M. R., Poustchi, H., Hemming, K., Marjani, H., Pourshams, A., Nateghi, A., et al. (2015). Polypill for the prevention of cardiovascular disease (PolyIran): Study design and rationale for a pragmatic cluster randomized controlled trial. European Journal of Preventive Cardiology, 22(12), 1609–1617. https://doi.org/10.1177/2047487314550803CrossRefPubMed Ostovaneh, M. R., Poustchi, H., Hemming, K., Marjani, H., Pourshams, A., Nateghi, A., et al. (2015). Polypill for the prevention of cardiovascular disease (PolyIran): Study design and rationale for a pragmatic cluster randomized controlled trial. European Journal of Preventive Cardiology, 22(12), 1609–1617. https://​doi.​org/​10.​1177/​2047487314550803​CrossRefPubMed
45.
Metagegevens
Titel
The association between diabetic complications and health-related quality of life in patients with type 2 diabetes: a cross-sectional study from Iran
Auteurs
Hassan Karami
Maryam Shirvani Shiri
Aziz Rezapour
Ranaa Sarvari Mehrabadi
Somayeh Afshari
Publicatiedatum
26-04-2021
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 7/2021
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-021-02792-7

Andere artikelen Uitgave 7/2021

Quality of Life Research 7/2021 Naar de uitgave