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Gepubliceerd in: Child Psychiatry & Human Development 2/2024

30-08-2022 | Original Article

Characteristics of the Symptoms of the Proposed ND-PAE Disorder in First Grade Children in a Community Sample

Auteurs: Julie A. Kable, Claire D. Coles, Jennifer E. Holton, Wendy O. Kalberg, Philip A. May, Christina D. Chambers, Gretchen Bandoli

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 2/2024

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Abstract

The proposed symptoms for Neurobehavioral Disorder Associated with Prenatal Alcohol Exposure (ND-PAE) were evaluated in children who participated in the Collaboration on Fetal Alcohol Spectrum Disorders Prevalence study. Children “at-risk” for ND-PAE (n = 204) were contrasted to children with no prenatal alcohol exposure, alcohol-related dysmorphia or growth deficits (n = 908). Symptoms were defined based on neuropsychological testing using two diagnostic threshold levels (1.0 and 1.5 STD). Individuals at risk for ND-PAE had higher endorsement rates of the self-regulation and adaptive impairments at the 1.0 threshold and of the neurocognitive and self-regulation impairments at the 1.5 threshold. Endorsement of the disorder significantly differed at the 1.0 threshold. Receiver operating characteristic curve analysis indicated that having an IQ below 70 was not predictive of the diagnosis but modifications of the IQ criterion improved predictive validity. Discrimination validity was poor without documentation of PAE which continues to be a necessity for a diagnosis of ND-PAE.
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Metagegevens
Titel
Characteristics of the Symptoms of the Proposed ND-PAE Disorder in First Grade Children in a Community Sample
Auteurs
Julie A. Kable
Claire D. Coles
Jennifer E. Holton
Wendy O. Kalberg
Philip A. May
Christina D. Chambers
Gretchen Bandoli
Publicatiedatum
30-08-2022
Uitgeverij
Springer US
Gepubliceerd in
Child Psychiatry & Human Development / Uitgave 2/2024
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI
https://doi.org/10.1007/s10578-022-01414-8

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