Skip to main content


Swipe om te navigeren naar een ander artikel

02-11-2019 | Uitgave 4/2020

Quality of Life Research 4/2020

Birth weight and quality of life in midlife: a 50-year follow-up study of 2079 individuals in Denmark

Quality of Life Research > Uitgave 4/2020
Emilie Rune Hegelund, Cathrine Lawaetz Wimmelmann, Jenna Marie Strizzi, Anna Paldam Folker, Erik Lykke Mortensen, Trine Flensborg-Madsen
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s11136-019-02348-w) contains supplementary material, which is available to authorized users.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.



Low birth weight has been associated with a higher risk of reduced quality of life (QoL) in children, adolescents, and young adults, but the influence seems to diminish over time. However, previous studies have mainly focused on health-related QoL and compared individuals with low birth weight with individuals without low birth weight. The purpose of the present cohort study was to investigate the influence of the entire range of birth weights on three distinct measures of QoL in midlife.


The study population consisted of all live-born singletons from the Copenhagen Perinatal Cohort (CPC, 1959–1961) who participated in a 50-year follow-up examination in 2009–2011 (N = 2079). Birth weight was measured by three pediatricians at birth. QoL was measured at the follow-up by the participants’ scores on three QoL self-report measures: The Satisfaction With Life Scale, the Vitality Scale of the Medical Outcomes Study 36-Item Short-Form Health Survey, and a single-item QoL measure based on the question: “How is your quality of life at the moment?”. General linear regression and binary logistic regression were used to estimate the association between birth weight and QoL in midlife.


Small, curvilinear associations of birth weight with life satisfaction, vitality, and the single-item QoL measure were found, suggesting that both low and high birth weights increase the risk of low satisfaction with life, low vitality and low QoL.


The study findings suggest that low and high-range birth weight exert a lasting influence on distinct, but complementary aspects of QoL in midlife.

Log in om toegang te krijgen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Podotherapeut Totaal

Binnen de bundel kunt u gebruik maken van boeken, tijdschriften, e-learnings, web-tv's en uitlegvideo's. BSL Podotherapeut Totaal is overal toegankelijk; via uw PC, tablet of smartphone.

Extra materiaal
Alleen toegankelijk voor geautoriseerde gebruikers
Over dit artikel

Andere artikelen Uitgave 4/2020

Quality of Life Research 4/2020 Naar de uitgave