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01-04-2004 | Artikelen

Auto-immuniteit en polymorfismen van het aangeboren en specifieke immuunsysteem

Auteurs: A. van Royen-Kerkhof, W. L. van der Pol, N. M. van Sorge, E. A. M. Sanders, W. Kuis

Gepubliceerd in: Tijdschrift voor Kindergeneeskunde | Uitgave 2/2004

Samenvatting

In dit artikel wordt ingegaan op de genetisch bepaalde varianten van het immuunsysteem die mogelijk een risicoverhogende, dan wel verlagende invloed kunnen hebben op het ontstaan of het beloop van auto-immuunziekten. Systemische lupus erythematosus en juveniele idiopathisch artritis dienen als voorbeeld. Er wordt hierbij onderscheid gemaakt tussen de aangeboren immuniteit (‘innate immunity’) en de verworven, specifieke immuniteit.

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Prahalad S, Ryan MH, Shear ES, et al. Twins concordant for juvenile rheumatoid arthritis. Arthritis Rheum 2000;43:2611-2.CrossRefPubMed

Prahalad S, Ryan MH, Shear ES, et al. Juvenile rheumatoid arthritis: linkage to HLA demonstrated by allele sharing in affected sibpairs. Arthritis Rheum 2000;43:2335-8.CrossRefPubMed

John S, Worthington J. Genetic epidemiology. Approaches to the genetic analysis of rheumatoid arthritis. Arthritis Res 2001;3:216-20.CrossRefPubMed

Llorente L, Richaud-Patin Y, Couderc J, et al. Dysregulation of interleukin-10 production in relatives of patients with systemic lupus erythematosus. Arthritis Rheum 1997;40:1429-35.CrossRefPubMed

Linden MW van der, Westendorp RG, Sturk A, et al. High interleukin-10 production in first-degree relatives of patients with generalized but not cutaneous lupus erythematosus. J Investig Med 2000;48:327-34.PubMed

Gibson AW, Edberg JC, Wu J, et al. Novel single nucleotide polymorphisms in the distal IL-10 promoter affect IL-10 production and enhance the risk of systemic lupus erythematosus. J Immunol 2001;166:3915-22.PubMed

Dorner T, Burmester GR. The role of B cells in rheumatoid arthritis: mechanisms and therapeutic targets. Curr Opin Rheumatol 2003;15:246-52.CrossRefPubMed

Kleer IM de, Kamphuis SM, Rijkers GT, et al. The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T cells directed to human heat-shock protein 60 capable of producing the regulatory cytokine interleukin-10. Arthritis Rheum 2003;48:2001-10.CrossRefPubMed

Roon JA van, Vuuren AJ van, Wijngaarden S, et al. Selective elimination of synovial inflammatory macrophages in rheumatoid arthritis by an Fcgamma receptor I-directed immunotoxin. Arthritis Rheum 2003;48:1229-38.CrossRefPubMed

Date Y, Seki N, Kamizono S, et al. Identification of a genetic risk factor for systemic juvenile rheumatoid arthritis in the 5'-flanking region of the TNFalpha gene and HLA genes. Arthritis Rheum 1999;42:2577-82.CrossRefPubMed

Barton A, John S, Ollier WE, et al. Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in Caucasians. Arthritis Rheum 2001;44:61-5.CrossRefPubMed

Rood MJ, Krugten MV van, Zanelli E, et al. TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus. Arthritis Rheum 2000;43:129-34.CrossRefPubMed

McDowell TL, Symons JA, Ploski R, et al. A genetic association between juvenile rheumatoid arthritis and a novel interleukin-1 alpha polymorphism. Arthritis Rheum 1995;38:221-8.CrossRefPubMed

Parks CG, Cooper GS, Dooley MA, et al. Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States. Ann Rheum Dis 2004;63:91-4.CrossRefPubMed

Fishman D, Faulds G, Jeffery R, et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998;102:1369-76.CrossRefPubMed

Donn RP, Barrett JH, Farhan A, et al. British Paediatric Rheumatology Study Group. Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis. Arthritis Rheum 2001;44:802-10.CrossRefPubMed

Schotte H, Schluter B, Rust S, et al. Interleukin-6 promoter polymorphism (-174 G/C) in Caucasian German patients with systemic lupus erythematosus. Rheumatology (Oxford) 2001;40:393-400.CrossRef

Crawley E, Kon S, Woo P. Hereditary predisposition to low interleukin-10 production in children with extended oligoarticular juvenile idiopathic arthritis. Rheumatology (Oxford) 2001;40:574-8.CrossRef

Llorente L, Richaud-Patin Y, Fior R, et al. In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sjogren's syndrome, and systemic lupus erythematosus. A potential mechanism of B lymphocyte hyperactivity and autoimmunity. Arthritis Rheum 1994;37:1647-55.CrossRefPubMed

Brunner HI, Ivaskova E, Haas JP, et al. Class I associations and frequencies of class II HLA-DRB alleles by RFLP analysis in children with rheumatoid-factor-negative juvenile chronic arthritis. Rheumatol Int 1993;13:83-8.CrossRefPubMed

Forre O, Dobloug JH, Hoyeraal HM, Thorsby E. HLA antigens in juvenile arthritis. Genetic basis for the different subtypes. Arthritis Rheum 1983;26:35-8.CrossRefPubMed

Edberg JC, Langefeld CD, Wu J, et al. Genetic linkage and association of Fcgamma receptor IIIA (CD16A) on chromosome 1q23 with human systemic lupus erythematosus. Arthritis Rheum 2002;46:2132-40.CrossRefPubMed

Karassa FB, Trikalinos TA, Ioannidis JP. Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis. Arthritis Rheum 2002;46:1563-71.CrossRefPubMed

Haseley LA, Wisnieski JJ, Denburg MR, et al. Antibodies to C1q in systemic lupus erythematosus: characteristics and relation to Fc gamma RIIA alleles. Kidney Int 1997;52:1375-80.CrossRefPubMed

Norsworthy P, Theodoridis E, Botto M, et al. Overrepresentation of the Fcgamma receptor type IIA R131/R131 genotype in caucasoid systemic lupus erythematosus patients with autoantibodies to C1q and glomerulonephritis. Arthritis Rheum 1999;42:1828-32.CrossRefPubMed

O'Duffy JD, O'Fallon WM, Hunder GG, et al. An attempt to predict the response to gold therapy in rheumatoid arthritis. Arthritis Rheum 1984;27:1210-7.CrossRefPubMed

Martinez A, Salido M, Bonilla G, et al. Association of the major histocompatibility complex with response to infliximab therapy in rheumatoid arthritis patients. Arthritis Rheum 2004;50:1077-82.CrossRefPubMed

Titel: Auto-immuniteit en polymorfismen van het aangeboren en specifieke immuunsysteem
Auteurs: A. van Royen-Kerkhof
W. L. van der Pol
N. M. van Sorge
E. A. M. Sanders
W. Kuis
Publicatiedatum: 01-04-2004
Uitgeverij: Bohn Stafleu van Loghum
Gepubliceerd in: Tijdschrift voor Kindergeneeskunde / Uitgave 2/2004
Print ISSN: 0376-7442
Elektronisch ISSN: 1875-6840
DOI: https://doi.org/10.1007/BF03061490

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