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01-02-2007 | Interuniversity Cardiology Institute of the Netherlands

Vasa vasorum and molecular imaging of atherosclerotic plaques using nonlinear contrast intravascular ultrasound

Auteurs: D. E. Goertz, M. E. Frijlink, R. Krams, N. de Jong, A. F. W. van der Steen

Gepubliceerd in: Netherlands Heart Journal | Uitgave 2/2007

Abstract

There is increasing evidence that presence and location of neovascular vasa vasorum play an important role in atherosclerotic plaque pathogenesis and stability. This paper describes a method to detect vasa vasorum with high contrast and high spatial resolution. It uses second harmonic or subharmonic intravascular ultrasound, in combination with ultrasound contrast agents. The same technology in combination with targeted contrast agents is suited for molecular imaging. The potential for vasa vasorum imaging is illustrated using an atherosclerotic animal model and the potential for molecular imaging is illustrated using phantom experiments.

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Titel: Vasa vasorum and molecular imaging of atherosclerotic plaques using nonlinear contrast intravascular ultrasound
Auteurs: D. E. Goertz
M. E. Frijlink
R. Krams
N. de Jong
A. F. W. van der Steen
Publicatiedatum: 01-02-2007
Uitgeverij: Bohn Stafleu van Loghum
Gepubliceerd in: Netherlands Heart Journal / Uitgave 2/2007
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI: https://doi.org/10.1007/BF03085959

Bohn Stafleu van Loghum

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