Skip to main content


Swipe om te navigeren naar een ander artikel


The influence of trait mindfulness on depression in multiple sclerosis: potential implications for treatment

Quality of Life Research
Jennifer R. Miller, Caroline Altaras, Nicholas A. Vissicchio, Vance Zemon, Jeffrey G. Portnoy, Elizabeth S. Gromisch, Jessica Sloan, Tuula Tyry, Frederick W. Foley
Belangrijke opmerkingen
An abstract containing information from this study was presented at a poster session at the Consortium of Multiple Sclerosis in Seattle, WA (May, 2019) The data also is a secondary analysis of a larger project: Gromisch, E. S., Sloan, J., Zemon, V., Tyry, T., Schairer, L. C., Snyder, S., & Foley, F. W. (2018). Development of the Multiple Sclerosis Resiliency Scale [MSRS]. Rehabilitation Psychology, 63(3), 357.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.



This study seeks to add to existing literature on depression and illness intrusiveness in chronic disorders by examining, (1) how the perceived intrusiveness of multiple sclerosis (MS) leads to depression, (2) and the mediating role trait mindfulness plays in this relationship


Participants (N = 755) were persons with MS (PwMS) recruited through the North American Research Committee on MS (NARCOMS) registry (a larger study). Participants completed the Illness Intrusiveness Ratings Scale, the Hospital Anxiety and Depression Scale and the Mindful Attention Awareness Scale. A mediation model assessed if trait mindfulness mediates the relationship between illness intrusiveness and depression


Illness intrusiveness predicted trait mindfulness (a =  − 4.54; p < .001), trait mindfulness predicted depression (b =  − .04; p < .001); there was a direct effect of illness intrusiveness on depression (c’ = 2.53; p < .001) and an indirect effect on depression (ab = .17, 95% BCa CI [.10, .25]) when trait mindfulness was in the model, which represented a medium size effect, R2med = .10 [95% CI .07, .14]


Trait mindfulness mediates the relationship between illness intrusiveness and depression in PwMS. Providers could provide psychoeducation on the benefits of mindfulness and mindfulness-based interventions.

Log in om toegang te krijgen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Podotherapeut Totaal

Binnen de bundel kunt u gebruik maken van boeken, tijdschriften, e-learnings, web-tv's en uitlegvideo's. BSL Podotherapeut Totaal is overal toegankelijk; via uw PC, tablet of smartphone.

Over dit artikel