Top

Quality of Life Research

Gepubliceerd in:

24-01-2022

The 5-year outcome of subjective quality of life in older schizophrenia patients

Auteurs: Sjors M. M. Lange, Paul D. Meesters, Max L. Stek, Brenda W. Penninx, Didi Rhebergen

Gepubliceerd in: Quality of Life Research | Uitgave 8/2022

Abstract

Purpose

Subjective quality of life (SQOL) is increasingly valued as an important outcome in schizophrenia treatment. The current study aims to gain insight into changes in SQOL during 5-year follow-up in older persons with schizophrenia spectrum disorders (SSD).

Methods

The sample consisted of a catchment area-based group of 75 older Dutch patients (mean age 66.0 years) with schizophrenia or schizoaffective disorder. Factor analysis was used to identify subdomains of SQOL, measured with the Manchester Short Assessment of Quality of Life (MANSA). 5-Year course trajectories and putative predictors of changes in SQOL and subdomains were examined using multivariable regression analyses.

Results

72% was stable in either a high or a low SQOL-status over time. When outcome was defined as change score, 36%, 20%, and 44% of participants, respectively, reported a clinically relevant improvement, deterioration, or no change of SQOL during follow-up. Three SQOL subdomains were identified with different course trajectories; 33% of participants reported an improvement in the subdomains satisfaction with ‘daily life’ and ‘personal circumstances.’ The largest number of declines (28%) was reported in the subdomain satisfaction with ‘physical and mental health.’ Predictors of positive total and subdomain SQOL-change scores were limited to a higher age of onset and higher baseline SQOL scores.

Conclusion

In this cohort of older persons, it was demonstrated that SQOL might considerably change during 5-year follow-up. As course trajectories differed among subdomains, separate evaluation of these subdomains is clinically relevant. Improvement of SQOL is an attainable goal in older SSD patients despite deteriorating physical health.

vorige artikel Research engagement and experiences of patients pre- and post-implant of a left ventricular assist device from the mechanical circulatory support measures of adjustment and quality of life (MCS A-QOL) study

volgende artikel The effect of polypharmacy on quality of life in adult patients with nonalcoholic fatty liver disease in the United States

World Health Organisation. (1998). Development of the world health organization WHOQOL-BREF quality of life assessment. Psychological Medicine, 28(3), 551–558. https://doi.org/10.1017/S0033291798006667CrossRef

Cohen, C. I., Meesters, P. D., & Zhao, J. (2015). New perspectives on schizophrenia in later life: Implications for treatment, policy, and research. The lancet Psychiatry., 2(4), 340–350. https://doi.org/10.1016/S2215-0366(15)00003-6CrossRefPubMed

Hoertel, N., Rotenberg, L., Blanco, C., Camus, V., Dubertret, C., Charlot, V., Schürhoff, F., Vandel, P., & Limson, F. (2020). CSA study Group A comprehensive model of predictors of quality of life in older adults with schizophrenia: Results from the CSA study. Social Psychiatry and Psychiatric Epidemiology. https://doi.org/10.1007/s00127-020-01880-2CrossRefPubMed

Folsom, D. P., Depp, C., Palmer, B. W., Mausbach, B. T., Golshan, S., Fellows, I., Cardenas, V., Patterson, T. L., Kraemer, H. C., & Jeste, D. V. (2009). Physical and mental health-related quality of life among older people with schizophrenia. Schizophrenia Research, 108(1–3), 207–213. https://doi.org/10.1016/j.schres.2008.12.008CrossRefPubMed

Meesters, P. D., Comijs, H. C., de Haan, L., Smit, J. H., Eikelenboom, P., Beekman, A. T. F., & Stek, M. L. (2013). Subjective quality of life and its determinants in a catchment area based population of elderly schizophrenia patients. Schizophrenia Research, 147(2–3), 275–280. https://doi.org/10.1016/j.schres.2013.04.030CrossRefPubMed

Bankole, A. O., Cohen, C. I., Vahia, I., Diwan, S., Kehn, M., & Ramirez, P. M. (2007). Factors affecting quality of life in a multiracial sample of older persons with schizophrenia. The American Journal of Geriatric Psychiatry, 15(12), 1015–1023. https://doi.org/10.1097/JGP.0b013e31805d8572CrossRefPubMed

Cohen, C. I., Vengassery, A., & Garcia Aracena, E. F. (2017). A Longitudinal Analysis of Quality of Life and Associated Factors in Older Adults with Schizophrenia Spectrum Disorder. The American Journal of Geriatric Psychiatry. https://doi.org/10.1016/j.jagp.2017.01.013CrossRefPubMedPubMedCentral

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. Text Revision (DSM-IV-TR). Washington DC 2000.

Priebe, S., Huxley, P., Knight, S., & Evans, S. (1999). Application and results of the manchester short assessment of quality of life (Mansa). International Journal of Social Psychiatry, 45(1), 7–12. https://doi.org/10.1177/002076409904500102CrossRefPubMed

10.

Oliver, J. P. J., Huxley, P. J., Priebe, S., & Kaiser, W. (1997). Measuring the quality of life of severely mentally ill people using the lancashire quality of life profile. Social Psychiatry and Psychiatric Epidemiology, 32(2), 76–83. https://doi.org/10.1007/BF00788924CrossRefPubMed

11.

Sheehan, D. V., Lecrubier, Y., Sheehan, K. H., Amorim, P., Janavs, J., Weiller, E., Hergueta, T., Baker, R., & Dunbar, G. C. (1998). The Mini-International Neuropsychiatric Interview (MINI): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. Journal of Clinical Psychiatry., 59, 22–33. https://doi.org/10.1016/S0924-9338(99)80239-9CrossRefPubMed

12.

Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13(2):261–276. http://www.ncbi.nlm.nih.gov/pubmed/3616518. Accessed January 16, 2017.

13.

Andreasen, N. C., Carpenter, W. T., Kane, J. M., Lasser, R. A., Marder, S. R., & Weinberger, D. R. (2005). Remission in schizophrenia: Proposed criteria and rationale for consensus. American Journal of Psychiatry, 162(3), 441–449. https://doi.org/10.1176/appi.ajp.162.3.441CrossRefPubMed

14.

Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1(3), 385–401. https://doi.org/10.1177/014662167700100306CrossRef

15.

Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). “Mini-mental state” A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189–198. https://doi.org/10.1016/0022-3956(75)90026-6CrossRefPubMed

16.

Depla, M. F. I. A., de Graaf, R., van Busschbach, J. T., & Heeren, T. J. (2003). Community integration of elderly mentally Ill persons in psychiatric hospitals and two types of residences. Psychiatric Services (Washington, D. C.), 54(5), 730–735. https://doi.org/10.1176/appi.ps.54.5.730CrossRef

17.

Schmitt, T. A. (2011). Current methodological considerations in exploratory and confirmatory factor analysis. Journal of Psychoeducational Assessment, 29(4), 304–321. https://doi.org/10.1177/0734282911406653CrossRef

18.

Eisen, S. V., Ranganathan, G., Seal, P., & Spiro, A. (2007). Measuring clinically meaningful change following mental health treatment. Journal of Behavioral Health Services and Research, 34(3), 272–289. https://doi.org/10.1007/s11414-007-9066-2CrossRefPubMed

19.

Hoertel, N., Rotenberg, L., Blanco, C., Pascal de Raykeer, R., Hanon, C., Kaladjian, A., & Limosin, F. (2019). CSA study group psychiatric symptoms and quality of life in older adults with schizophrenia spectrum disorder: Results from a multicenter study. European Archives of Psychiatry and Clinical Neuroscience, 270(6), 673–688. https://doi.org/10.1007/s00406-019-01026-9CrossRefPubMed

20.

Jeste, D. V., Wolkowitz, O. M., & Palmer, B. W. (2011). Divergent trajectories of physical, cognitive, and psychosocial aging in schizophrenia. Schizophrenia Bulletin, 37(3), 451–455. https://doi.org/10.1093/schbul/sbr026CrossRefPubMedPubMedCentral

21.

Boyer, L., Baumstarck, K., Boucekine, M., Blanc, J., Lançon, C., & Auquier, P. (2013). Measuring quality of life in patients with schizophrenia:An overview. Expert Review of Pharmacoeconomics & Outcomes Research, 13(3), 343–349. https://doi.org/10.1586/erp.13.15CrossRef

22.

Petkari, E., Giacco, D., & Priebe, S. (2019). Factorial structure of the Manchester Short Assessment of Quality of Life in patients with schizophrenia-spectrum disorders. Quality of Life Research. https://doi.org/10.1007/s11136-019-02356-wCrossRefPubMedPubMedCentral

23.

Brink, M., & Andersen, K. (2020). Subjective health-related quality of life in community-dwelling middle-aged and older adults with early-onset schizophrenia. Nordic Journal of Psychiatry. https://doi.org/10.1080/08039488.2020.1769186CrossRefPubMed

24.

Priebe, S., Reininghaus, U., McCabe, R., Burns, T., Eklund, M., Hansson, L., Junghan, U., Kallert, T., van Nieuwenhuizen, C., Ruggeri, M., Slade, M., & Wang, D. (2010). Factors influencing subjective quality of life in patients with schizophrenia and other mental disorders: A pooled analysis. Schizophrenia Research, 121(1–3), 251–258. https://doi.org/10.1016/j.schres.2009.12.020CrossRefPubMed

25.

Solomon, R., Kirwin, P., Van Ness, P. H., O’Leary, J., & Fried, T. R. (2010). Trajectories of quality of life in older persons with advanced illness. Journal of the American Geriatrics Society, 58(5), 837–843. https://doi.org/10.1111/j.1532-5415.2010.02817.xCrossRefPubMedPubMedCentral

26.

Stone, A. A., Schwartz, J. E., Broderick, J. E., Deaton, A., & Kahneman, D. (2010). A snapshot of the age distribution of psychological well-being in the United States. PNAS, 107(22), 9985–9990. https://doi.org/10.1073/pnas.1003744107CrossRefPubMedPubMedCentral

27.

Plagnol A. Subjective Well-Being over the Life Course: Conceptualizations and Evaluations. 2010. https://muse.jhu.edu/article/528046/summary.

28.

Kao, Y. C., & Liu, Y. P. (2010). Effects of age of onset on clinical characteristics in schizophrenia spectrum disorders. BMC Psychiatry. https://doi.org/10.1186/1471-244X-10-63CrossRefPubMedPubMedCentral

29.

Karow, A., Wittmann, L., Schöttle, D., Schäfer, I., & Lambert, M. (2014). The assessment of quality of life in clinical practice in patients with schizophrenia. Dialogues in Clinical Neuroscience, 16(2), 185–195.CrossRef

30.

Rotstein, A., Roe, D., Gelkopf, M., & Levine, S. Z. (2018). Age of onset and quality of life among males and females with schizophrenia: A national study. European Psychiatry, 53, 100–106. https://doi.org/10.1016/j.eurpsy.2018.06.004CrossRefPubMed

Titel: The 5-year outcome of subjective quality of life in older schizophrenia patients
Auteurs: Sjors M. M. Lange
Paul D. Meesters
Max L. Stek
Brenda W. Penninx
Didi Rhebergen
Publicatiedatum: 24-01-2022
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 8/2022
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-021-03062-2

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Purpose

Methods

Results

Conclusion

Log in om toegang te krijgen

Andere artikelen Uitgave 8/2022

The effect of polypharmacy on quality of life in adult patients with nonalcoholic fatty liver disease in the United States

Time to deterioration of patient-reported outcomes in non-small cell lung cancer: exploring different definitions

Illness cognitions and health-related quality of life in liver transplant patients related to length of stay, comorbidities and complications

The health-related quality of life in hyperhidrosis and co-morbidities

Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study

Correction to: Time to deterioration of patient-reported outcomes in non-small cell lung cancer: exploring different definitions