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Journal of Autism and Developmental Disorders

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01-11-2007 | Original Paper

Relevance of Donepezil in Enhancing Learning and Memory in Special Populations: A Review of the Literature

Auteurs: J. Helen Yoo, Maria G. Valdovinos, Dean C. Williams

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2007

Abstract

This review discusses the laboratory and clinical research supporting the rationale for the efficacy of donepezil (Aricept® USA) in enhancing cognition in autism, Alzheimer disease, Down syndrome, traumatic brain injury, Attention Deficit Hyperactivity Disorder (ADHD), and schizophrenia. While preliminary animal models have shown effective, human studies exclusive of Alzheimer disease are sparse. Although attention and memory are unlikely a sole operation of the cholinergic system, evidence indicates a promising direction for further examination of this hypothesis in autism. Studies that examine changes in operationally defined behaviors and reliable and valid measure of changes in attention and memory are needed.

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Titel: Relevance of Donepezil in Enhancing Learning and Memory in Special Populations: A Review of the Literature
Auteurs: J. Helen Yoo
Maria G. Valdovinos
Dean C. Williams
Publicatiedatum: 01-11-2007
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 10/2007
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-006-0322-8

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