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Gepubliceerd in: Verslaving 1/2013

01-03-2013 | Middelen

Nieuwe Psychoactieve Stoffen (NPS): niets nieuws onder de zon

Auteurs: Raoul Koning, Raymond Niesink

Gepubliceerd in: Verslaving | Uitgave 1/2013

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Extract

Designerdrugs, ‘legal highs’, ‘research chemicals’, badzout of hoe ook aangeduid: nieuwe psychoactieve stoffen, meestal afgekort als NPS, zijn de afgelopen jaren uitgegroeid tot een fenomeen van wereldformaat. Op nationaal, Europees en mondiaal niveau maken we ons er ernstige zorgen over, niet in de laatste plaats vanwege de veronderstelde (soms fatale) gevolgen voor de volksgezondheid. Maar waar hebben we het eigenlijk over? NPS bestrijken een breed scala van stoffen met farmacologische eigenschappen en effecten die vergelijkbaar zijn met die van internationaal gecontroleerde drugs. Omdat het om zo’n breed scala gaat is het moeilijk een exacte definitie te geven. …
Literatuur
go back to reference Ayres, T.C. & Bond, J.W. (2012). A chemical analysis examining the pharmacology of novel psychoactive substances freely available over the internet and their impact on public (ill)health. Legal highs or illegal highs? BMJ Open, 2, e000977.PubMedCrossRef Ayres, T.C. & Bond, J.W. (2012). A chemical analysis examining the pharmacology of novel psychoactive substances freely available over the internet and their impact on public (ill)health. Legal highs or illegal highs? BMJ Open, 2, e000977.PubMedCrossRef
go back to reference Bossong, M.P., Dijk, J.P. van & Niesink, R.J.M. (2005). Methylone and mCPP, two new drugs of abuse? Addiction Biology, 10, 321–323.PubMedCrossRef Bossong, M.P., Dijk, J.P. van & Niesink, R.J.M. (2005). Methylone and mCPP, two new drugs of abuse? Addiction Biology, 10, 321–323.PubMedCrossRef
go back to reference Brandt, S.D., Sumnall, H.R., Measham, F. & Cole, J. (2010). Analyses of second- generation ’legal highs’ in the UK: initial findings. Drug Test Analysis, 2, 377–382.CrossRef Brandt, S.D., Sumnall, H.R., Measham, F. & Cole, J. (2010). Analyses of second- generation ’legal highs’ in the UK: initial findings. Drug Test Analysis, 2, 377–382.CrossRef
go back to reference Brunt, M., Poortman, A., Niesink, R.J.M. & Brink, W. Van Den (2011). Instability of the ecstasy market and a new kid on the block: mephedrone. Journal of Psychopharmacology, 25,1543–1547.PubMedCrossRef Brunt, M., Poortman, A., Niesink, R.J.M. & Brink, W. Van Den (2011). Instability of the ecstasy market and a new kid on the block: mephedrone. Journal of Psychopharmacology, 25,1543–1547.PubMedCrossRef
go back to reference Curran, H.V. & Monaghan, L. (2001). In and out of the K-hole: a comparison of the acute and residual effects of ketamine in frequent and infrequent ketamine users.Addiction, 96, 749–760. Curran, H.V. & Monaghan, L. (2001). In and out of the K-hole: a comparison of the acute and residual effects of ketamine in frequent and infrequent ketamine users.Addiction, 96, 749–760.
go back to reference Curran, H.V. & Morgan, C. (2000). Cognitive, dissociative and psychotogenic effects of ketamine in recreational users on the night of drug use and 3 days later. Addiction, 95, 575–590.PubMedCrossRef Curran, H.V. & Morgan, C. (2000). Cognitive, dissociative and psychotogenic effects of ketamine in recreational users on the night of drug use and 3 days later. Addiction, 95, 575–590.PubMedCrossRef
go back to reference Dargan, P.I., Albert, S. & Wood, D.M. (2010). Mephedrone use and associated adverse effects in school and college/university students before the UK legislation change. QJM, an International Journal of Mediane, 103, 875–879.CrossRef Dargan, P.I., Albert, S. & Wood, D.M. (2010). Mephedrone use and associated adverse effects in school and college/university students before the UK legislation change. QJM, an International Journal of Mediane, 103, 875–879.CrossRef
go back to reference EMCDDA (2011). Report on the risk assessment of mephedrone in theframeworkofthe council decision on new psychoactive substances risk assessments (issue 9). Lissabon: EMCDDA. EMCDDA (2011). Report on the risk assessment of mephedrone in theframeworkofthe council decision on new psychoactive substances risk assessments (issue 9). Lissabon: EMCDDA.
go back to reference EMCDDA (2012). Annual report on thestate ofthe drugs problem in Europe. Lissabon: EMCDDA. EMCDDA (2012). Annual report on thestate ofthe drugs problem in Europe. Lissabon: EMCDDA.
go back to reference Fisher, M.B., Henne, K.R. & Boer, J. (2006). The complexities inherent in attempts to decrease drug clearance by blocking sites of CYP-mediated metabolism. Current Opinion in Drug Discovery Development, 9,101–109.PubMed Fisher, M.B., Henne, K.R. & Boer, J. (2006). The complexities inherent in attempts to decrease drug clearance by blocking sites of CYP-mediated metabolism. Current Opinion in Drug Discovery Development, 9,101–109.PubMed
go back to reference Gallup Organisation (2011). Flash Eurobarometer 330. Youth attitudes on drugs. Survey conducted by the Gallup Organization, Hungary upon the request of Directorate-General Justice. Internet: ec.europa.eu/public_opinion/archives/ flash_arch_en.htm (15 januari 2013). Gallup Organisation (2011). Flash Eurobarometer 330. Youth attitudes on drugs. Survey conducted by the Gallup Organization, Hungary upon the request of Directorate-General Justice. Internet: ec.europa.eu/public_opinion/archives/ flash_arch_en.htm (15 januari 2013).
go back to reference Ghaziuddin, N.,Welch, K. & Greden, J. (2003). Central serotonergic effects of m-chlorophenylpiperazine (mCPP) among normal control adolescents. Neuro- psychopharmacology, 28,133–139.PubMedCrossRef Ghaziuddin, N.,Welch, K. & Greden, J. (2003). Central serotonergic effects of m-chlorophenylpiperazine (mCPP) among normal control adolescents. Neuro- psychopharmacology, 28,133–139.PubMedCrossRef
go back to reference Gunderson, E.W., Haughey, H.M., Ait-Daoud, N., Joshi, A.S. & Hart, C.L. (2012). ’Spice’ and ’K2’ herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications ofsynthetic cannabinoid use in humans. American Journal of the Addictions, 21, 320–326.CrossRef Gunderson, E.W., Haughey, H.M., Ait-Daoud, N., Joshi, A.S. & Hart, C.L. (2012). ’Spice’ and ’K2’ herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications ofsynthetic cannabinoid use in humans. American Journal of the Addictions, 21, 320–326.CrossRef
go back to reference Hoyte, C.O., Jacob, J,, Monte, A.A., Al-Jumaan, M., Bronstein, A.C. & Heard, K.J. (2012). A characterization of synthetic cannabinoid exposures reported to the National Poison Data System in 2010. Annals of Emergency Medicine, 60, 435–438.PubMedCrossRef Hoyte, C.O., Jacob, J,, Monte, A.A., Al-Jumaan, M., Bronstein, A.C. & Heard, K.J. (2012). A characterization of synthetic cannabinoid exposures reported to the National Poison Data System in 2010. Annals of Emergency Medicine, 60, 435–438.PubMedCrossRef
go back to reference Nagai, F., Nonaka, R. & Satoh Hisashi Kamimura, K. (2007). The effects of non- medically used psychoactive drugs on monoamine neurotransmission in rat brain. European Journal of Pharmacology, 559,132–137.PubMedCrossRef Nagai, F., Nonaka, R. & Satoh Hisashi Kamimura, K. (2007). The effects of non- medically used psychoactive drugs on monoamine neurotransmission in rat brain. European Journal of Pharmacology, 559,132–137.PubMedCrossRef
go back to reference Niesink, R.J.M. (2011). Qat: farmacologische en toxicologische aspecten. Verslaving, 7, 40–50.CrossRef Niesink, R.J.M. (2011). Qat: farmacologische en toxicologische aspecten. Verslaving, 7, 40–50.CrossRef
go back to reference Schifano, F., Albanese, A., Fergus, S., Stair, J.L., Deluca, P., Corazza, O., Davey, Z., Corkery, J., Siemann, H., Scherbaum, N., Farre, M., Torrens, M., Demetro- vics, Z. & Ghodse, A.H. (2011). Mephedrone (4-methylmethcathinone; ’meow meow’): chemical, pharmacological and clinical issues. Psychopharmacology (Berl), 214, 593–602.PubMedCrossRef Schifano, F., Albanese, A., Fergus, S., Stair, J.L., Deluca, P., Corazza, O., Davey, Z., Corkery, J., Siemann, H., Scherbaum, N., Farre, M., Torrens, M., Demetro- vics, Z. & Ghodse, A.H. (2011). Mephedrone (4-methylmethcathinone; ’meow meow’): chemical, pharmacological and clinical issues. Psychopharmacology (Berl), 214, 593–602.PubMedCrossRef
go back to reference Shulgin, A. & Shulgin, A. (1991). PIHKAL. Phenetylamines I have known and loved. Berkely, CA: Transform Press. Shulgin, A. & Shulgin, A. (1991). PIHKAL. Phenetylamines I have known and loved. Berkely, CA: Transform Press.
go back to reference Shulgin, A. & Shulgin, A. (1997). TIHKAL. Tryptamines I have known and loved. The continuation. Berkely, CA: Transform Press. Shulgin, A. & Shulgin, A. (1997). TIHKAL. Tryptamines I have known and loved. The continuation. Berkely, CA: Transform Press.
go back to reference Tancer, M.E. & Johanson, C.-E. (2001). The subjective effects of MDMA and mCPP in moderate MDMA users. Drug and Alcohol Dependence, 65, 97–101.PubMedCrossRef Tancer, M.E. & Johanson, C.-E. (2001). The subjective effects of MDMA and mCPP in moderate MDMA users. Drug and Alcohol Dependence, 65, 97–101.PubMedCrossRef
go back to reference Urquhart, C. (2004). Drugs and dance as Israelis blot out intifada. Nightlife in Tel Aviv on a par with the best in London and New York. The Guardian, 4 September. Urquhart, C. (2004). Drugs and dance as Israelis blot out intifada. Nightlife in Tel Aviv on a par with the best in London and New York. The Guardian, 4 September.
go back to reference Ward, J., Rhyee, S. & Plansky, J. (2011). Methoxetamine: a novel ketamine analog and growing health-care concern. Clinical Toxicology, 49, 874–875.PubMedCrossRef Ward, J., Rhyee, S. & Plansky, J. (2011). Methoxetamine: a novel ketamine analog and growing health-care concern. Clinical Toxicology, 49, 874–875.PubMedCrossRef
go back to reference Winstock, A., Mitcheson, L., Ramsey, J., Davies, S., Puchnarewicz, M. & Marsden, J. (2011). Mephedrone: use, subjective effects and health risks. Addiction, 106, 1991–1996.PubMedCrossRef Winstock, A., Mitcheson, L., Ramsey, J., Davies, S., Puchnarewicz, M. & Marsden, J. (2011). Mephedrone: use, subjective effects and health risks. Addiction, 106, 1991–1996.PubMedCrossRef
go back to reference Wood, D.M., Davies, S., Puchnarewicz, M., Johnston, A. & Dargan, P.I. (2012). Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine. European Journal of Clinical Pharmacology, 68, 853–856.PubMedCrossRef Wood, D.M., Davies, S., Puchnarewicz, M., Johnston, A. & Dargan, P.I. (2012). Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine. European Journal of Clinical Pharmacology, 68, 853–856.PubMedCrossRef
Metagegevens
Titel
Nieuwe Psychoactieve Stoffen (NPS): niets nieuws onder de zon
Auteurs
Raoul Koning
Raymond Niesink
Publicatiedatum
01-03-2013
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Verslaving / Uitgave 1/2013
Print ISSN: 1574-1842
Elektronisch ISSN: 1875-7073
DOI
https://doi.org/10.1007/s12501-013-0007-x

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