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Gepubliceerd in: Cognitive Therapy and Research 1/2024

14-08-2023 | Original Article

Moderators and Preliminary Processes of Change in a Randomized Controlled Trial of a Fully Automated, Website Delivering AEBT for Adults with Trichotillomania

Auteurs: Leila K. Capel, Julie M. Petersen, Michael E. Levin, Michael P. Twohig

Gepubliceerd in: Cognitive Therapy and Research | Uitgave 1/2024

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Abstract

Introduction

Access to treatment for trichotillomania has barriers and many people never receive evidence-based treatment. Understanding what treatments and modalities work, and how people get better through those treatments and modalities, is needed.

Methods

We include analyses of moderators of treatment outcomes and preliminary processes of change from a randomized controlled trial assessing the efficacy of a fully automated website delivering acceptance-enhanced behavior therapy (AEBT) for adults (N = 81) with trichotillomania. All participants received an eight-module website of AEBT, and assessments were completed at baseline, mid-, post-treatment, and a one-month follow-up. Using multilevel modeling, the moderation effects of baseline trichotillomania specific psychological flexibility, age, baseline and time -varying anxiety, and baseline and time varying depression were explored. Preliminary process of change using psychological flexibility was explored.

Results

Baseline trichotillomania-specific psychological flexibility is correlated with changes in symptom severity over time but not by condition. Lower trichotillomania specific psychological flexibility at baseline was associated with better outcomes. Age also moderated treatment outcomes, specifically, participants between 18 and 30 had better treatment outcomes than participants over 30 years old. Baseline anxiety correlated with symptom severity but did not moderate intervention effects. Changes in anxiety were correlated with symptom severity over time. Baseline depression was not a significant moderator. Preliminary process of change analyses suggests that changes in psychological flexibility is correlated with changes in trichotillomania symptom severity across time. This relationship did not change in strength over time and was not moderated by condition.

Conclusion

This study highlights how baseline trichotillomania specific psychological flexibility and anxiety impact changes in symptom severity and the function in a website delivered AEBT for adults with trichotillomania. Additionally, it provides preliminary support of the role of trichotillomania-specific psychological flexibility as a process of change in treatment of trichotillomania. Implications are discussed.
Literatuur
go back to reference Alexander, J. R., Houghton, D. C., Twohig, M. P., Franklin, M. E., Saunders, S. M., Neal-Barnett, A. M., Compton, S. N., & Woods, D. W. (2017). Clarifying the relationship between Trichotillomania and anxiety. Journal of obsessive-compulsive and related disorders, 13, 30–34.CrossRefPubMedPubMedCentral Alexander, J. R., Houghton, D. C., Twohig, M. P., Franklin, M. E., Saunders, S. M., Neal-Barnett, A. M., Compton, S. N., & Woods, D. W. (2017). Clarifying the relationship between Trichotillomania and anxiety. Journal of obsessive-compulsive and related disorders, 13, 30–34.CrossRefPubMedPubMedCentral
go back to reference Arch, J. J., Wolitzky-Taylor, K. B., Eifert, G. H., & Craske, M. G. (2012). Longitudinal treatment mediation of traditional cognitive behavioral therapy and acceptance and commitment therapy for anxiety disorders. Behaviour Research and Therapy, 50(7–8), 469–478.CrossRefPubMed Arch, J. J., Wolitzky-Taylor, K. B., Eifert, G. H., & Craske, M. G. (2012). Longitudinal treatment mediation of traditional cognitive behavioral therapy and acceptance and commitment therapy for anxiety disorders. Behaviour Research and Therapy, 50(7–8), 469–478.CrossRefPubMed
go back to reference American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: DSM-5™ (5th ed.). American Psychiatric Publishing.CrossRef American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders: DSM-5™ (5th ed.). American Psychiatric Publishing.CrossRef
go back to reference Capel, L. K., Petersen, J. M., Becker, M. R., Levin, M. L., & Twohig, M. P. (2023). Examining the efficacy and feasibility of a web-based acceptance enhanced behavior therapy for trichotillomania: A randomized waitlist-controlled trial. Journal of Obsessive-Compulsive and Related Disorders., 37, 100800.CrossRef Capel, L. K., Petersen, J. M., Becker, M. R., Levin, M. L., & Twohig, M. P. (2023). Examining the efficacy and feasibility of a web-based acceptance enhanced behavior therapy for trichotillomania: A randomized waitlist-controlled trial. Journal of Obsessive-Compulsive and Related Disorders., 37, 100800.CrossRef
go back to reference Elliott, A. J., & Fuqua, R. W. (2002). Acceptability of treatments for trichotillomania: Effects of age and severity. Behavior Modification, 26(3), 378–399.CrossRefPubMed Elliott, A. J., & Fuqua, R. W. (2002). Acceptability of treatments for trichotillomania: Effects of age and severity. Behavior Modification, 26(3), 378–399.CrossRefPubMed
go back to reference Flessner, C. A., Woods, D. W., Franklin, M. E., Cashin, S. E., & Keuthen, N. J. (2008). The milwaukee inventory for subtypes of trichotillomania- adult version (MIST-A): Development of an instrument for the assessment of “focused” and “automatic” hair pulling. Journal of Psychopathology Behavior and Assessment, 30, 20–30. https://doi.org/10.1007/s10862-007-9073-xCrossRef Flessner, C. A., Woods, D. W., Franklin, M. E., Cashin, S. E., & Keuthen, N. J. (2008). The milwaukee inventory for subtypes of trichotillomania- adult version (MIST-A): Development of an instrument for the assessment of “focused” and “automatic” hair pulling. Journal of Psychopathology Behavior and Assessment, 30, 20–30. https://​doi.​org/​10.​1007/​s10862-007-9073-xCrossRef
go back to reference Franklin, M. E., Edson, A. L., & Freeman, J. B. (2010). Behavior therapy for pediatric trichotillomania: Exploring the effects of age on treatment outcome. Child and Adolescent Psychiatry and Mental Health, 4, 1–6.CrossRef Franklin, M. E., Edson, A. L., & Freeman, J. B. (2010). Behavior therapy for pediatric trichotillomania: Exploring the effects of age on treatment outcome. Child and Adolescent Psychiatry and Mental Health, 4, 1–6.CrossRef
go back to reference Franklin, M. E., Zagrabbe, K., & Benavides, K. L. (2011). Trichotillomania and its treatment: A review and recommendations. Expert Review of Neurotherapeutics, 11(8), 1165–1174.CrossRefPubMedPubMedCentral Franklin, M. E., Zagrabbe, K., & Benavides, K. L. (2011). Trichotillomania and its treatment: A review and recommendations. Expert Review of Neurotherapeutics, 11(8), 1165–1174.CrossRefPubMedPubMedCentral
go back to reference Grant, J. E., Redden, S. A., Leppink, E. W., & Chamberlain, S. R. (2017a). Trichotillomania and co-occurring anxiety. Comprehensive Psychiatry, 72, 1–5.CrossRefPubMed Grant, J. E., Redden, S. A., Leppink, E. W., & Chamberlain, S. R. (2017a). Trichotillomania and co-occurring anxiety. Comprehensive Psychiatry, 72, 1–5.CrossRefPubMed
go back to reference Haaland, A. T., Ekeland, S. O., Moen, E. M., Vogel, P. A., Haseth, S., Mellingen, K., Himle, J. A., Woods, D. W., & Hummelen, B. (2017). ACT-enhanced behavior therapy in group format for trichotillomania: An effectiveness study. Journal of Obsessive-Compulsive and Related Disorders, 12, 109–116.CrossRef Haaland, A. T., Ekeland, S. O., Moen, E. M., Vogel, P. A., Haseth, S., Mellingen, K., Himle, J. A., Woods, D. W., & Hummelen, B. (2017). ACT-enhanced behavior therapy in group format for trichotillomania: An effectiveness study. Journal of Obsessive-Compulsive and Related Disorders, 12, 109–116.CrossRef
go back to reference Hofmann, S. G., & Hayes, S. C. (2019). The future of intervention science: Process-based therapy. Clinical Psychological Science, 7(1), 37–50.CrossRefPubMed Hofmann, S. G., & Hayes, S. C. (2019). The future of intervention science: Process-based therapy. Clinical Psychological Science, 7(1), 37–50.CrossRefPubMed
go back to reference Houghton, D. C., Capriotti, M. R., De Nadai, A. S., Compton, S. N., Twohig, M. P., Neal-Barnett, A. M., Saunders, S. M., Franklin, M. E., Woods, D. W. (2015). Definining treatment response in trichotillomania: A signal detection anaylsis. Journal of Anxiety Disorders, 36, 44-51, https://doi.org/10.1016/j.janxdis.2015.09.008 Houghton, D. C., Capriotti, M. R., De Nadai, A. S., Compton, S. N., Twohig, M. P., Neal-Barnett, A. M., Saunders, S. M., Franklin, M. E., Woods, D. W. (2015). Definining treatment response in trichotillomania: A signal detection anaylsis. Journal of Anxiety Disorders, 36, 44-51, https://​doi.​org/​10.​1016/​j.​janxdis.​2015.​09.​008
go back to reference Hox, J. J., Moerbeek, M., & Van de Schoot, R. (2017). Multilevel analysis: Techniques and applications (3rd ed.). Taylor & Francis Group.CrossRef Hox, J. J., Moerbeek, M., & Van de Schoot, R. (2017). Multilevel analysis: Techniques and applications (3rd ed.). Taylor & Francis Group.CrossRef
go back to reference Keuthen, N. J., O’Sullivan, R. L., Ricciardi, J. N., Shera, D., Savage, C. R., Borgmann, A. S., Jenike, M. A., & Baer, L. (1995). The massachusetts general hospital (MGH) hairpulling scale: Development and factor analyses. Psychotherapy and Psychosomatics, 64(3), 141–145. https://doi.org/10.1159/000289003CrossRefPubMed Keuthen, N. J., O’Sullivan, R. L., Ricciardi, J. N., Shera, D., Savage, C. R., Borgmann, A. S., Jenike, M. A., & Baer, L. (1995). The massachusetts general hospital (MGH) hairpulling scale: Development and factor analyses. Psychotherapy and Psychosomatics, 64(3), 141–145. https://​doi.​org/​10.​1159/​000289003CrossRefPubMed
go back to reference Lovibond, S. H., & Lovibond, P. F. (1995). Manual for the Depression Anxiety Stress Scales. Sydney psychology foundation. Lovibond, S. H., & Lovibond, P. F. (1995). Manual for the Depression Anxiety Stress Scales. Sydney psychology foundation.
go back to reference Morris, S. H., Zickgraf, H. F., Dingfelder, H. E., & Franklin, M. E. (2013). Habit reversal training in trichotillomania: Guide for the clinician. Expert Review of Neurotherapeutics, 13(9), 1069–1077.CrossRefPubMed Morris, S. H., Zickgraf, H. F., Dingfelder, H. E., & Franklin, M. E. (2013). Habit reversal training in trichotillomania: Guide for the clinician. Expert Review of Neurotherapeutics, 13(9), 1069–1077.CrossRefPubMed
go back to reference Ong, C. W., & Eustis, E. H. (2021). Psychological flexibility. In M. P. Twohig, M. E. Levin, & J. M. Petersen (Eds.), The Oxford Handbook of Acceptance and Commitment Therapy. Oxford University Press. Ong, C. W., & Eustis, E. H. (2021). Psychological flexibility. In M. P. Twohig, M. E. Levin, & J. M. Petersen (Eds.), The Oxford Handbook of Acceptance and Commitment Therapy. Oxford University Press.
go back to reference Ong, C. W., Woods, D. W., Franklin, M. E., Saunders, S. M., Neal-Barnett, A. M., Compton, S. N., & Twohig, M. P. (2023). The role of psychological flexibility in acceptance-enhanced behavior therapy for trichotillomania: Moderation and mediation findings. Behaviour Research and Therapy, 164, 104302.CrossRefPubMed Ong, C. W., Woods, D. W., Franklin, M. E., Saunders, S. M., Neal-Barnett, A. M., Compton, S. N., & Twohig, M. P. (2023). The role of psychological flexibility in acceptance-enhanced behavior therapy for trichotillomania: Moderation and mediation findings. Behaviour Research and Therapy, 164, 104302.CrossRefPubMed
go back to reference Osman, A., Wong, J. L., Bagge, C. L., Freedenthal, S., Gutierrez, P. M., & Lozano, G. (2012). The depression anxiety stress Scales—21 (DASS-21): Further examination of dimensions, scale reliability, and correlates. Journal of Clinical Psychology, 68(12), 1322–1338.CrossRefPubMed Osman, A., Wong, J. L., Bagge, C. L., Freedenthal, S., Gutierrez, P. M., & Lozano, G. (2012). The depression anxiety stress Scales—21 (DASS-21): Further examination of dimensions, scale reliability, and correlates. Journal of Clinical Psychology, 68(12), 1322–1338.CrossRefPubMed
go back to reference Petersen, J. M., Capel, L. K., Levin, M. E., & Twohig, M. P. (2022). Moderators and processes of change in a pilot randomized controlled trial of acceptance-enhanced behavior therapy for trichotillomania in adolescents. Journal of Obsessive-Compulsive and Related Disorders., 35, 100757.CrossRef Petersen, J. M., Capel, L. K., Levin, M. E., & Twohig, M. P. (2022). Moderators and processes of change in a pilot randomized controlled trial of acceptance-enhanced behavior therapy for trichotillomania in adolescents. Journal of Obsessive-Compulsive and Related Disorders., 35, 100757.CrossRef
go back to reference R Core Team. (2022). R: A language and environment for statistical computing. R Foundation for Statistical Computing. R Core Team. (2022). R: A language and environment for statistical computing. R Foundation for Statistical Computing.
go back to reference Tung, E. S., Flessner, C. A., Grant, J. E., & Keuthen, N. J. (2015). Predictors of life disability in trichotillomania. Comprehensive Psychiatry, 56, 239–244.CrossRefPubMed Tung, E. S., Flessner, C. A., Grant, J. E., & Keuthen, N. J. (2015). Predictors of life disability in trichotillomania. Comprehensive Psychiatry, 56, 239–244.CrossRefPubMed
go back to reference Woods, D. W., & Twohig, M. P. (2023). Trichotillomania: An ACT-enhanced Behavior Therapy Approach Therapist Guide (2nd ed.). Oxford University Press. Woods, D. W., & Twohig, M. P. (2023). Trichotillomania: An ACT-enhanced Behavior Therapy Approach Therapist Guide (2nd ed.). Oxford University Press.
go back to reference Woods, D. W., Ely, L. J., Bauer, C. C., Twohig, M. P., Saunders, S. M., Compton, S. N., Espil, F. M., Neal-Barnett, A., Alexander, J. R., Walther, M. R., & Cahill, S. P. (2022). Acceptance-enhanced behavior therapy for trichotillomania in adults: A randomized clinical trial. Behaviour Research and Therapy, 158, 104187.CrossRefPubMedPubMedCentral Woods, D. W., Ely, L. J., Bauer, C. C., Twohig, M. P., Saunders, S. M., Compton, S. N., Espil, F. M., Neal-Barnett, A., Alexander, J. R., Walther, M. R., & Cahill, S. P. (2022). Acceptance-enhanced behavior therapy for trichotillomania in adults: A randomized clinical trial. Behaviour Research and Therapy, 158, 104187.CrossRefPubMedPubMedCentral
Metagegevens
Titel
Moderators and Preliminary Processes of Change in a Randomized Controlled Trial of a Fully Automated, Website Delivering AEBT for Adults with Trichotillomania
Auteurs
Leila K. Capel
Julie M. Petersen
Michael E. Levin
Michael P. Twohig
Publicatiedatum
14-08-2023
Uitgeverij
Springer US
Gepubliceerd in
Cognitive Therapy and Research / Uitgave 1/2024
Print ISSN: 0147-5916
Elektronisch ISSN: 1573-2819
DOI
https://doi.org/10.1007/s10608-023-10418-0

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