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Gepubliceerd in: Huisarts en wetenschap 1/2009

01-01-2009 | Onderzoek

Kwaliteit van leven bij rokers: zijn functionele beperkingen belangrijker dan longfunctie?

Auteurs: Roeland Geijer, Alfred Sachs, Theo Verheij, Huib Kerstjens, Marijke Kuyvenhoven, Arno Hoes

Gepubliceerd in: Huisarts en wetenschap | Uitgave 1/2009

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Samenvatting

Geijer RMM, Sachs APE, Verheij TJM, Kerstjens HAM, Kuyvenhoven MM, Hoes AW. Kwaliteit van leven bij rokers: zijn functionele beperkingen belangrijker dan longfunctie? Huisarts Wet 2009;51(1):39-44.
Achtergrond De internationaal gebruikelijke indeling van het Global Initiative for Chronic Obstructive Lung Disease (GOLD) voor chronisch obstructief longlijden (COPD) is alleen gebaseerd op het geforceerde expiratoire volume in één seconde (FEV1) en houdt geen rekening met het lichamelijk functioneren.
Doel Wij wilden achterhalen in hoeverre de kwaliteit van leven van COPD-patiënten verband houdt met beperkingen in het lichamelijk functioneren zoals gemeten met de dyspneuschaal van de Medical Research Council (MRC), en met de mate van luchtwegobstructie.
Methode De deelnemers aan het onderzoek waren 395 mannelijke rokers van 40 tot 65 jaar (gemiddelde leeftijd 55,4 jaar, rookhistorie gemiddeld 27,1 pakjaren), zonder eerdere diagnose van COPD en ingeschreven in een huisartsenpraktijk in IJsselstein. Zij ondergingen een spirometrietest en vulden een algemene (SF-36) en een ziektespecifieke (QOL-RIQ) vragenlijst in over de kwaliteit van leven.
Resultaat Bij 99 deelnemers (25,1%) vonden wij functiebeperkingen en bij 159 deelnemers (40,2%) maten wij een luchtwegobstructie. De beperking in lichamelijk functioneren correleerde sterker met alle kwaliteit-van-levensubschalen dan de ernst van de luchtwegobstructie. Ook in de multivariate analyse bleef dit verband sterker.
Conclusie Bij rokers van middelbare leeftijd geeft de MRC-schaal een betere indruk van de kwaliteit van leven dan de GOLD-stadiëring. Toekomstige indelingen van COPD dienen meer rekening te houden met beperkingen van het lichamelijk functioneren door dyspneu en niet alleen uit te gaan van het FEV1.
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Metagegevens
Titel
Kwaliteit van leven bij rokers: zijn functionele beperkingen belangrijker dan longfunctie?
Auteurs
Roeland Geijer
Alfred Sachs
Theo Verheij
Huib Kerstjens
Marijke Kuyvenhoven
Arno Hoes
Publicatiedatum
01-01-2009
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Huisarts en wetenschap / Uitgave 1/2009
Print ISSN: 0018-7070
Elektronisch ISSN: 1876-5912
DOI
https://doi.org/10.1007/BF03085495

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