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Gepubliceerd in: Quality of Life Research 5/2024

09-12-2023 | Review

Health-related quality of life of people with heart failure in low- and middle-income countries: a systematic review and meta-analysis

Auteurs: Henok Mulugeta, Peter M. Sinclair, Amanda Wilson

Gepubliceerd in: Quality of Life Research | Uitgave 5/2024

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Abstract

Purpose

Heart failure is a global health concern and associated with poor health-related quality of life and increased mortality. There is a disproportionate burden on patients and health systems in low- and middle-income countries. This systematic review and meta-analysis estimates the health-related quality of life of people with heart failure in low- and middle-income countries.

Methods

A systematic literature search was conducted to identify relevant studies from January 2012 to November 2022 using the following databases: MEDLINE, EMBASE, PsycINFO, CINAHL, Web of Science, Scopus and JBI EBP database. Study screening, quality appraisal and data extraction were conducted using JBI methodology. A random-effects model was used to perform the meta-analysis. Heterogeneity was assessed using the I2 statistic. All statistical analyses were done in STATA version 17.

Results

A total of 33 studies with 5612 participants were included in this review. The Minnesota Living with Heart Failure Questionnaire (MLHFQ) and the Short-Form-36 questionnaire (SF-36) were the most used instruments across 19 and 8 studies, respectively. The pooled mean MLHFQ and SF-36 scores using the random-effects model were 46.08 (95% CI 35.06, 57.10) and 41.23 (95% CI 36.63, 45.83), respectively. In a subgroup analysis using both instruments, the highest health-related quality-of-life scores occurred in studies with inpatient participants.

Conclusion

The overall health-related quality of life of people with heart failure in low- and middle-income countries is poor. Strategies should be strategically developed to improve the health-related quality of life of people with heart failure in these countries.

Systematic review registration

PROSPERO CRD42022377781.
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Metagegevens
Titel
Health-related quality of life of people with heart failure in low- and middle-income countries: a systematic review and meta-analysis
Auteurs
Henok Mulugeta
Peter M. Sinclair
Amanda Wilson
Publicatiedatum
09-12-2023
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 5/2024
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-023-03563-2

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