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06-09-2023

Health-related quality of life among adults newly diagnosed with pulmonary tuberculosis in Lagos State, Nigeria: a prospective study

Auteurs: Bisola I. Adebayo, Olusola A. Adejumo, Olumuyiwa O. Odusanya

Gepubliceerd in: Quality of Life Research | Uitgave 1/2024

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Abstract

Purpose

Tuberculosis (TB) has far-reaching effects on the social, mental, and emotional well-being of patients and consequently, their health-related quality of life (HRQOL). Few studies in Nigeria have examined changes in quality of life over the course of treatment. changes in (PTB) and factors associated with HRQOL.

Methods

A prospective cohort study was conducted with patients recruited from health facilities in Lagos State. The World Health Organization Quality of Life Instrument, Short-Form (WHOQOL-BREF) was used to assess HRQOL. A semi-structured questionnaire was also administered to elicit information on socio-demographic characteristics and the medical and social history of the respondents. Data were analysed using Statistical Package for the Social Sciences (SPSS) version 23. A repeated measures analysis of variance (ANOVA) test with polynomial contrasts was used to assess how domain scores varied over time. Multivariable analysis was conducted using generalized estimating equations (GEE) to assess change in HRQOL and its predictors.

Results

Two hundred and ten patients, predominantly male [108 (63.3%)] were recruited. The mean age was 36.7 ± 12.3 years. The HRQOL was impaired in all four domains at baseline. However, HRQOL scores increased over the treatment period with the largest improvement being in the ‘environment’ domain, where mean scores increased from 45.27 ± 14.59 to 61.28 ± 15.86. The proportion of respondents that expressed satisfaction with their health increased from 13.5% at baseline to 55.7% at the end of treatment. Low socio-economic status, delay in presentation, and an HIV-positive status were found to be significantly associated with reduced HRQOL at baseline (p < 0.05). In the multivariable longitudinal analysis, patients who were employed had higher HRQOL scores while persistent symptoms and a delay in presentation (≥ 4 weeks) were negatively associated with change in HRQOL scores over the course of treatment.

Conclusion

The HRQOL of respondents progressively improved over the six-month treatment period. However, change in HRQOL was influenced by a delay in presentation and persistence of symptoms. The study also highlights the need for increased recognition of patient-reported outcomes as an adjunct outcome measure.
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Literatuur
1.
go back to reference World Health Organization. Global Tuberculosis Report. 2021 Retrieved February 19, 2022, 978 92 4 156450 2. Retrieved February 19, 2022 World Health Organization. Global Tuberculosis Report. 2021 Retrieved February 19, 2022, 978 92 4 156450 2. Retrieved February 19, 2022
6.
go back to reference Olowoporoku AO, Longhurst JWS, Barnes JH. Framing air pollution as a major health risk in Lagos, Nigeria. In: WIT Transactions on Ecology and the Environment. WIT Press; 2012. p. 479–486. https://doi.org/10.2495/AIR120421. Retrieved August 9, 2017 Olowoporoku AO, Longhurst JWS, Barnes JH. Framing air pollution as a major health risk in Lagos, Nigeria. In: WIT Transactions on Ecology and the Environment. WIT Press; 2012. p. 479–486. https://​doi.​org/​10.​2495/​AIR120421. Retrieved August 9, 2017
8.
go back to reference Hays RD, Sherbourne CD, Mazel RM. User’s Manual for the Medical Outcomes Study (MOS) Core Measures of Health-Related Quality of Life. 1995; 157 Hays RD, Sherbourne CD, Mazel RM. User’s Manual for the Medical Outcomes Study (MOS) Core Measures of Health-Related Quality of Life. 1995; 157
9.
go back to reference Babikako, H. M., Neuhauser, D., Katamba, A., & Mupere, E. (2010). Feasibility, reliability and validity of health-related quality of life questionnaire among adult pulmonary tuberculosis patients in urban Uganda: cross-sectional study. Health and Quality of Life Outcomes, 8, 93.CrossRefPubMedPubMedCentral Babikako, H. M., Neuhauser, D., Katamba, A., & Mupere, E. (2010). Feasibility, reliability and validity of health-related quality of life questionnaire among adult pulmonary tuberculosis patients in urban Uganda: cross-sectional study. Health and Quality of Life Outcomes, 8, 93.CrossRefPubMedPubMedCentral
13.
17.
go back to reference Adeyeye, O. O., Ogunleye, O. O., Coker, A., Kuyinu, Y., Bamisile, R. T., Ekrikpo, U., & Onadeko, B. (2014). Factors influencing quality of life and predictors of low quality of life scores in patients on treatment for pulmonary tuberculosis: A cross sectional study. Journal of Public Health in Africa, 5(2), 88–92. https://doi.org/10.4081/jphia.2014.366CrossRef Adeyeye, O. O., Ogunleye, O. O., Coker, A., Kuyinu, Y., Bamisile, R. T., Ekrikpo, U., & Onadeko, B. (2014). Factors influencing quality of life and predictors of low quality of life scores in patients on treatment for pulmonary tuberculosis: A cross sectional study. Journal of Public Health in Africa, 5(2), 88–92. https://​doi.​org/​10.​4081/​jphia.​2014.​366CrossRef
18.
go back to reference Ozoh, O. B., Ojo, O. O., Dania, M. G., Dede, S. K., Adegboyega, O. A., Irurhe, N. K., Olowoyeye, M., & Adeyeye, O. O. (2021). Impact of post-tuberculosis lung disease on health-related quality of life in patients from two tertiary hospitals in Lagos, Nigeria. African Journal of Thoracic and Critical Care Medicine., 27(2), 46–52. https://doi.org/10.7196/AJTCCM.2021.v27i2.135CrossRef Ozoh, O. B., Ojo, O. O., Dania, M. G., Dede, S. K., Adegboyega, O. A., Irurhe, N. K., Olowoyeye, M., & Adeyeye, O. O. (2021). Impact of post-tuberculosis lung disease on health-related quality of life in patients from two tertiary hospitals in Lagos, Nigeria. African Journal of Thoracic and Critical Care Medicine., 27(2), 46–52. https://​doi.​org/​10.​7196/​AJTCCM.​2021.​v27i2.​135CrossRef
21.
go back to reference Lagos State Archives and Record Bureau (LASRAB). 2014 Profile of Lagos State 2014 Lagos State Archives and Record Bureau (LASRAB). 2014 Profile of Lagos State 2014
23.
go back to reference NTBLCP. National Tuberculosis, Leprosy and Buruli ulcer Management and control Guidelines. 2015. NTBLCP. National Tuberculosis, Leprosy and Buruli ulcer Management and control Guidelines. 2015.
27.
28.
go back to reference Akinpelu, A., Maruf, F. A., & Adegoke, B. (2007). Validation of a Yoruba translation of the World Health Organization’s quality of life scale-short form among stroke survivors in Southwest Nigeria. African Journal of Biomedical science., 35(4), 417–424. Akinpelu, A., Maruf, F. A., & Adegoke, B. (2007). Validation of a Yoruba translation of the World Health Organization’s quality of life scale-short form among stroke survivors in Southwest Nigeria. African Journal of Biomedical science., 35(4), 417–424.
36.
go back to reference Sule, A. G., Odeigah, L. O., Alabi, K. M., Issa, B. A., Shittu, R. O., Joseph, A. I., Abiola, O. F., & Natie, B. N. (2014). Quality of Life of Patients with Tuberculosis in a Nigerian Teaching Hospital. Turkish Journal of Family Medicine and Primary Care, 8(2), 39–47. https://doi.org/10.5455/tjfmpc.46982CrossRef Sule, A. G., Odeigah, L. O., Alabi, K. M., Issa, B. A., Shittu, R. O., Joseph, A. I., Abiola, O. F., & Natie, B. N. (2014). Quality of Life of Patients with Tuberculosis in a Nigerian Teaching Hospital. Turkish Journal of Family Medicine and Primary Care, 8(2), 39–47. https://​doi.​org/​10.​5455/​tjfmpc.​46982CrossRef
37.
go back to reference Issa, B. A., Yussuf, A. D., & Kuranga, S. I. (2009). Depression comorbidity among patients with tuberculosis in a university teaching hospital outpatient clinic in Nigeria. Mental Health in Family Medicine, 6(3), 133–138.PubMedPubMedCentral Issa, B. A., Yussuf, A. D., & Kuranga, S. I. (2009). Depression comorbidity among patients with tuberculosis in a university teaching hospital outpatient clinic in Nigeria. Mental Health in Family Medicine, 6(3), 133–138.PubMedPubMedCentral
43.
go back to reference Umar, S. B. A., Ayinmode, B. A., Alabi, K. M., Issa, B. A., Kuranga, S., Amoko, A., & Odeigah, L. O. (2020). Family support and depression among adult patients with tuberculosis attending a tertiary hospital in north-central Nigeria. Nigerian Journal of Family Practice, 10(4), 20–27. Umar, S. B. A., Ayinmode, B. A., Alabi, K. M., Issa, B. A., Kuranga, S., Amoko, A., & Odeigah, L. O. (2020). Family support and depression among adult patients with tuberculosis attending a tertiary hospital in north-central Nigeria. Nigerian Journal of Family Practice, 10(4), 20–27.
48.
go back to reference Okunoye, O. C., Asekomeh, G. E., Otike-Odibi, B., Iyagba, M. A., Onwuchekwa, A. C., God’spowerEshiofeAsekomeh. (2014). Quality of life of people living with HIV/AIDS in port harcourt Nigeria. The Nigerian Health Journal, 14(1), 06–12. Okunoye, O. C., Asekomeh, G. E., Otike-Odibi, B., Iyagba, M. A., Onwuchekwa, A. C., God’spowerEshiofeAsekomeh. (2014). Quality of life of people living with HIV/AIDS in port harcourt Nigeria. The Nigerian Health Journal, 14(1), 06–12.
50.
go back to reference Bauer, M., Ahmed, S., Benedetti, A., Greenaway, C., Lalli, M., Leavens, A., Menzies, D., Vadeboncoeur, C., Vissandjée, B., Wynne, A., & Schwartzman, K. (2015). Health-related quality of life and tuberculosis: a longitudinal cohort study. Health and Quality of Life Outcomes, 13(1), 2213–2235. https://doi.org/10.1186/s12955-015-0250-4CrossRef Bauer, M., Ahmed, S., Benedetti, A., Greenaway, C., Lalli, M., Leavens, A., Menzies, D., Vadeboncoeur, C., Vissandjée, B., Wynne, A., & Schwartzman, K. (2015). Health-related quality of life and tuberculosis: a longitudinal cohort study. Health and Quality of Life Outcomes, 13(1), 2213–2235. https://​doi.​org/​10.​1186/​s12955-015-0250-4CrossRef
52.
go back to reference Unalan, D., Soyuer, F., & Ozturk, A. (2012). Comparison of SF-36 and WHOQOL-100 life quality scales in early period tuberculosis subjects. Journal of the Pakistan Medical Association, 62(11), 1161–1167.PubMed Unalan, D., Soyuer, F., & Ozturk, A. (2012). Comparison of SF-36 and WHOQOL-100 life quality scales in early period tuberculosis subjects. Journal of the Pakistan Medical Association, 62(11), 1161–1167.PubMed
54.
go back to reference Duyan, V., Kurt, B., Aktas, Z., Duyan, G. C., & Kulkul, D. O. (2005). Relationship between quality of life and characteristics of patients hospitalised with tuberculosis. International Journal of Tuberculosis and Lung Disease, 9(12), 1361–1366. Duyan, V., Kurt, B., Aktas, Z., Duyan, G. C., & Kulkul, D. O. (2005). Relationship between quality of life and characteristics of patients hospitalised with tuberculosis. International Journal of Tuberculosis and Lung Disease, 9(12), 1361–1366.
Metagegevens
Titel
Health-related quality of life among adults newly diagnosed with pulmonary tuberculosis in Lagos State, Nigeria: a prospective study
Auteurs
Bisola I. Adebayo
Olusola A. Adejumo
Olumuyiwa O. Odusanya
Publicatiedatum
06-09-2023
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 1/2024
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-023-03506-x