Skip to main content
Mijn bibliotheek
Shop
Nieuws Boeken Tijdschriften E-learning Web-tv Video Audio
Tips voor Mijn BSL
UITGEBREID ZOEKEN
Inloggen
Top
Gepubliceerd in:
Introduction: An Evidence-Based Approach for Prevention and Management of Surgical Complications hoofdstuk lezen eerste hoofdstuk lezen

2014 | OriginalPaper | Hoofdstuk

16. Guided Tissue Regeneration in Endodontic Surgery: Principle, Efficacy, and Complications

Auteurs : Louis M. Lin, BDS, DMD, PhD, Domenico Ricucci, MD, DDS, Thomas von Arx, Prof. Dr. Med. Dent.

Gepubliceerd in: Complications in Endodontic Surgery

Uitgeverij: Springer Berlin Heidelberg

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail
    Link delen
publish
Publiceer nu

Abstract

The concept of guided tissue regeneration (GTR) in endodontic surgery is derived from periodontal regenerative therapy for periodontal disease. Periapical tissue regeneration will occur predictably after endodontic surgery if intra- and extraradicular infections are controlled by adequate root-end resection and complete retrograde seal of the root canal. Indications for GTR technique in endodontic surgery are limited and should be clearly recognized to prevent misuse. They include: combined endodontic-periodontic lesions, through-and-through bone lesions, and large periapical lesions almost involving the alveolar crest bone. The materials, such as barrier membranes and bone grafts used in GTR technique should be biocompatible and approved by the FDA. Possible pre-surgical, intra-surgical, and post-surgical complications of GTR technique in endodontic surgery must be prevented to avoid failures. GTR technique in endodontic surgery could improve periapical wound healing in through-and through bone lesions and possibly in cases with large periapical lesions.
vorige hoofdstuk Medicolegal Consideration in Endodontics: General and Surgical Aspects
Literatuur
1.
2.
3.
4.
Apaydin ES, Torabinejad M. The effect of calcium sulfate on hard tissue healing after periapical surgery. J Endod. 2004;30:17–20.PubMedCrossRef
5.
Artzi Z, Wasersprung N, Weinreb M, et al. Effect of guided tissue regeneration on newly formed bone and cementum in periapical tissue healing after endodontic surgery: an in vivo study in the cat. J Endod. 2012;38:163–9.PubMedCrossRef
6.
Baek S-H, Kim S. Bone repair of experimentally induced through-and–through defects by Gore-Tex, Guidor, and Vicryl in ferrets: a pilot study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;91:710–4.PubMedCrossRef
7.
8.
Beck-Coon RJ, Newton CW, Kafrawy AH. An in vivo study of the use of nonresorbable ceramic hydroxyapatite as an alloplastic graft material in periapical surgery. Oral Surg Oral Med Oral Pathol. 1991;71:483–8.PubMedCrossRef
9.
Bergenholtz G, Wikesjö UME, Sorensen RG, et al. Observation on healing following endodontic surgery in nonhuman primates (Macaca fascicularis): effect of rhBMP-2. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:116–25.PubMedCrossRef
10.
Bernabé PF, Gomes-Filho JE, Cintra LT, et al. Histologic evaluation of the use of membrane, bone graft, and MTA in apical surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:309–14.PubMedCrossRef
11.
Britian SK, von Arx T, Schenk RK, et al. The use of guided tissue regeneration principles in endodontic surgery for induced chronic periodontic-endodontic lesions: a clinical, radiographic and histological evaluation. J Periodontol. 2005;76:450–60.CrossRef
12.
Calori GM, Mazza E, Colombo M, et al. The use of bone-graft substitutes in large bone defects: Any specific need? Injury. 2011;42:S56–63.PubMedCrossRef
13.
Chastain SR, Kundu AK, Dhar S, et al. Adhesion of mesenchymal stem cells to polymer scaffolds occurs via distinct ECM ligands and controls their osteogenic differentiation. J Biomed Mater Res A. 2006;78: 73–85.PubMedCrossRef
14.
Chen M-F, Hwang T-L, Hung C-F. Human liver regeneration after major hepatectomy. Ann Surg. 1991;3:227–9.CrossRef
15.
Cooper GM, Mooney MP, Gosain AK, et al. Testing the critical size in calvarial bone defects: revisiting the concept of a critical-size defect. Plast Reconstr Surg. 2010;125:1685–92.PubMedCentralPubMedCrossRef
16.
Dahlin C, Linde A, Gottlow J, Nyman S. Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg. 1988;81:672–6.PubMedCrossRef
17.
Dahlin C, Gottlow J, Linde A, Nyman S. Healing of maxillary and mandibular bone defects using a membrane technique: an experimental study in monkeys. Scand J Plast Reconstr Surg Hand Surg. 1990;24:13–9.PubMedCrossRef
18.
Douglass A, Wallace K, Parr R, et al. Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury. J Hepatol. 2008;49:88–98.PubMedCrossRef
19.
De Long Jr WG, Einhorn TA, Koval K, et al. Bone grafts and bone graft substitutes in orthopaedic trauma surgery. J Bone Joint Surg Am. 2007;89:649–58.CrossRef
20.
Dimitrious R, Tsiridis E, Giannoudis PV. Current concepts of molecular aspects of bone healing. Injury. 2005;36:1392–404.CrossRef
21.
Douthitt JC, Gutmann JL, Witherspoon DE. Histologic assessment of healing after the use of a bioresorbable membrane in the management of buccal bone loss concomitant with periapical surgery. J Endod. 2001;27:404–10.PubMedCrossRef
22.
Ebihara Y, Masuya M, Larue AC, et al. Hematopoietic origin of fibroblasts: II – in vitro studies of fibroblasts, CFU-F, and fibrocytes. Exp Hematol. 2006;34:219–29.PubMedCrossRef
23.
Elek SD, Conen PE. The virulence of Staphylococcus pyogenes for man. A study of the problems of wound infection. Br J Exp Pathol. 1957;38:573–88.PubMedCentralPubMed
24.
Garrett K, Kerr M, Hartwell G, et al. The effect of bioresorbable matrix barrier in endodontic surgery on the rate of periapical healing: an in vivo study. J Endod. 2002;28:503–6.PubMedCrossRef
25.
Giannoudis PV, Dinopoulos H, Tsiridis E. Bone substitutes: an update. Injury. 2005;365:S20–7.CrossRef
26.
Goyal B, Tewari S, Duhan J, et al. Comparative evaluation of platelet-rich plasma and guided tissue regeneration membrane in the healing of apicomarginal defects: a clinical study. J Endod. 2011;37:773–80.PubMedCrossRef
27.
Grung B, Molven O, Halse A. Periapical surgery in a Norwegian county hospital: follow-up findings of 477 teeth. J Endod. 1990;16:411–7.PubMedCrossRef
28.
Gurtner GC, Werner S, Barrandon Y, et al. Wound repair and regeneration. Nature. 2008;453:314–21.PubMedCrossRef
29.
Halse A, Molven O, Grung B. Follow-up after periapical surgery: the value of the one-year control. Dent Traumatol. 1991;7:246–50.CrossRef
30.
31.
Hjorting-Hansen E, Andreasen JO. Incomplete bone healing of experimental cavities in dog mandibles. Br J Oral Surg. 1971;9:33–40.PubMedCrossRef
32.
Hotary K, Lin X-Y, Allen E, et al. A cancer cell metalloproteinase regulates the basement membrane transmigration program. Genes Dev. 2006;20:2673–86.PubMedCentralPubMedCrossRef
33.
Huh JY, Choi BH, Kim BY, et al. Critical size defect in the canine mandible. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:296–301.PubMedCrossRef
34.
Janicki P, Schmidmaier G. What should be the characteristics of the ideal bone graft substitute? Combining scaffold with growth factors and/or stem cells. Injury. 2011;42:S77–81.PubMedCrossRef
35.
36.
Kissin E, Korn JH. Apoptosis and myofibroblasts in the pathogenesis of systemic sclerosis. Curr Rheumatol Rep. 2002;4:129–35.PubMedCrossRef
37.
Krummel TM, Michna BA, Thomas BL, et al. Transforming growth factor beta (TGF-β) induces fibrosis in a fetal wound healing. J Pediatr Surg. 1988;23:647–52.PubMedCrossRef
38.
Lauffenburger DA, Horwitz AF. Cell migration: a physically integrated molecular process. Cell. 1996;84:359–69.PubMedCrossRef
39.
40.
Lin L, Skribner J, Shovlin F, Langeland K. Periapical surgery of mandibular posterior teeth: anatomical and surgical considerations. J Endod. 1983;9:496–501.PubMedCrossRef
41.
Lin L, Chance K, Shovlin F, et al. Oroantral communication in periapical surgery of maxillary posterior teeth. J Endod. 1985;11:40–4.PubMedCrossRef
42.
Lin L, Chen MY-H, Ricucci D, et al. Guided tissue regeneration in periapical surgery. J Endod. 2010;36:618–25.PubMedCrossRef
43.
Maguire H, Torabinejad M, McMillan P, et al. Effects of resorbable membrane placement and human osteogenic protein-1 on hard tissue healing after periapical surgery in cats. J Endod. 1998;24:720–5.PubMedCrossRef
44.
Matsura T, Hosokawa R, Okamoto K, et al. Diverse mechanisms of osteoblast spreading on hydroxyapatite and titanium. Biomaterials. 2000;21:1121–7.CrossRef
45.
Molven O, Halse A, Grung B. Incomplete healing (scar tissue) after periapical surgery – radiographic findings 8 to 12 years after treatment. J Endod. 1996;22:264–8.PubMedCrossRef
46.
Mutsaers SE, Bishop JE, McGrouther G, et al. Mechanisms of tissue repair: from wound healing to fibrosis. Int J Biochem Cell Biol. 1997;29:5–17.PubMedCrossRef
47.
Naylor J, Mines P, Anderson A, Kwon D. The use of guided tissue regeneration techniques among endodontists: a web-based survey. J Endod. 2011;37: 1495–8.PubMedCrossRef
48.
Needleman IG, Giedrys-Leeper E, Tucker RJ, Worthington NV. Results of guided tissue regeneration are highly variable. Evid Based Dent. 2002;3: 12–23.CrossRef
49.
Needleman IG, Worthington HV, Giedrys-Leeper E, Tucker RJ. Guided tissue regeneration for periodontal infra-bony defects. Cochrane Database Syst Rev. 2006;(2);CD001724.
50.
51.
Nyman S, Gottlow J, Lindhe J, et al. New attachment formation by guided tissue regeneration. J Periodontal Res. 1987;22:252–4.PubMedCrossRef
52.
Oh S-L, Fouad AF, Park S-H. Treatment strategy for guided tissue regeneration in combined endodontic-periodontic lesions: case report and literature review. J Endod. 2009;35:1331–6.PubMedCrossRef
53.
Palecek SP, Loftus JC, Ginsberg MH, et al. Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness. Nature. 1997;385:537–40.PubMedCrossRef
54.
Parikh SN. Bone graft substitutes: past, present, future. J Postgrad Med. 2002;48:142–8.PubMed
55.
Pecora G, Kim S, Celletti R, Davarpanah M. The guided tissue regeneration principle in endodontic surgery: one-year postoperative results of large periapical lesions. Int Endod J. 1995;28:41–6.PubMedCrossRef
56.
Pecora G, Baek S-H, Rethnam S, Kim S. Barrier membrane techniques in endodontic surgery. Dent Clin N Am. 1997;41:585–602.PubMed
57.
Pecora G, de Leonardis D, Ibrahim N, et al. The use of calcium sulfate in the surgical treatment of a “through and through” periapical lesion. Int Endod J. 2001;34:189–97.PubMedCrossRef
58.
Pinto VS, Zuolo ML, Mellonig JT. Guided bone regeneration in the treatment of a large periapical lesion: a case report. Pract Periodontics Aesthet Dent. 1995;7:76–81.PubMed
59.
Pompa DG. Guided tissue repair of complete buccal dehiscence associated with periapical defects: a clinical prospective study. J Am Dent Assoc. 1997;128:989–97.PubMedCrossRef
60.
Rankow HJ, Krasner PR. Endodontic applications of guided tissue regeneration in endodontic surgery. J Endod. 1996;22:34–43.PubMedCrossRef
61.
Regan JD, Gutmann JL, Lacopino AM, et al. Response of periradicular tissue to growth factors introduced into the surgical site in the root-end filling material. Int Endod J. 1999;32:171–82.PubMedCrossRef
62.
Rud J, Andreasen JO, Moller-Jensen JE. A multivariate analysis of the influence of various factors upon healing after endodontic surgery. Int J Oral Surg. 1972;1:258–71.PubMedCrossRef
63.
Saad AY, Abdellatief EM. Healing assessment of osseous defects of periapical lesions associated with failed endodontically treated teeth with use of freeze-dried bone allograft. Oral Surg Oral Med Oral Pathol. 1991;71:612–7.PubMedCrossRef
64.
Sarrazy V, Billet F, Micallef L, et al. Mechanisms of pathological scarring: role of myofibroblasts and current development. Wound Repair Regen. 2011;19:S10–5.PubMedCrossRef
65.
Schwartz F, Herten M, Ferrari D, et al. Guided tissue regeneration at dehiscence-type defects using biphasic hydroxyapatite + beta tricalcium phosphate (Bone Ceramic) or a collagen-coated natural bone mineral (BioOss Collagen): an immunohistochemical study in dogs. Int J Oral Maxillofac Surg. 2007;36:1198–206.CrossRef
66.
Serini G, Bochaton-Piallat M-L, Ropraz P, et al. The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-ß1. J Cell Biol. 1998;142:873–81.PubMedCentralPubMedCrossRef
67.
Setzer FC, Shah SB, Kohli MR, et al. Outcome of endodontic surgery: a meta-analysis of the literature – part 1: comparison of traditional root-end surgery and endodontic microsurgery. J Endod. 2010;36:1757–65.PubMedCrossRef
68.
Shi H, Ma J, Zhao N, et al. Periodontal regeneration in experimentally-induced alveolar bone dehiscence by an improved porous biphasic calcium phosphate ceramic in beagle dogs. J Mater Sci Mater Med. 2008;19:3515–24.PubMedCrossRef
69.
Siebers MC, ter Brugge PJ, Walboomers XF, et al. Integrins as linker proteins between osteoblasts and bone replacement materials. A critical review. Biomaterials. 2005;26:137–46.PubMedCrossRef
70.
Stassen LFA, Hislop WS, Still DM, et al. Use of anorganic bone in periapical defects following apical surgery: a prospective trial. Br J Oral Maxillofac Surg. 1994;32:83–5.PubMedCrossRef
71.
72.
Taschieri S, del Fabbro M, Testori T, et al. Efficacy of xenogenic bone grafting with guided tissue regeneration in the management of bone defects after surgical endodontics. J Oral Maxillofac Surg. 2007;65:1121–7.PubMedCrossRef
73.
Taschieri S, del Fabbro M, Testori T, et al. Efficacy of guided tissue regeneration in the management of through-and-through lesions following surgical endodontics: a preliminary study. Int J Periodontics Restorative Dent. 2008;28:265–71.PubMed
74.
Tobon SL, Arismendi JA, Marin ML, et al. Comparison between a conventional technique and two bone regeneration techniques in periradicular surgery. Int Endod J. 2002;35:635–41.PubMedCrossRef
75.
Tseng CC, Harn WM, Chen YH, et al. A new approach to the treatment of true combined endodontic-periodontic lesions by the guided tissue regeneration technique. J Endod. 1996;22:693–6.PubMedCrossRef
76.
Tsesis I, Faivishevsky V, Kfir A, Rosen E. Outcomes of surgical endodontic treatment performed by a modern technique: a meta-analysis of the literature. J Endod. 2009;35:1505–11.PubMedCrossRef
77.
Tsesis I, Rosen E, Tamse A, et al. Effect of guided tissue regeneration on the outcome of surgical endodontic treatment: a systematic review and meta-analysis. J Endod. 2011;37:1039–45.PubMedCrossRef
78.
Tsesis I, Rosen E, Taschieri S, et al. Outcomes of surgical endodontic treatment performed by a modern technique: an updated meta-analysis of the literature. J Endod. 2013;39:332–9.PubMedCrossRef
79.
Urist MR, DeLange RJ, Finerman GA. Bone cell differentiation and growth factors. Science. 1983;220: 680–6.PubMedCrossRef
80.
Van der Veer WM, Bloemen MC, Ulrich MM, et al. Potential cellular and molecular causes of hypertrophic scar formation. Burns. 2009;35:15–29.PubMedCrossRef
81.
Vissink A, Burlage FR, Spijkervert FKL, et al. Prevention and treatment of the consequences of head and neck radiotherapy. Crit Rev Oral Biol Med. 2003;14:213–25.PubMedCrossRef
82.
von Arx T, Häfliger J, Chappuis V. Neurosensory disturbances following bone harvesting in the symphysis. A prospective clinical study. Clin Oral Implants Res. 2005;16:432–9.CrossRef
83.
von Arx T, Cochran DL. Rationale for the application of the GTR principle using a barrier membrane in endodontic surgery: a proposal of classification and literature review. Int J Periodontics Restorative Dent. 2001;21:127–39.
84.
von Arx T, Chappuis V, Winzap-Kälin C, Bornstein MM. Laser Doppler flowmetry for assessment of anterior mandibular teeth in conjunction with bone harvesting in the symphysis: a clinical pilot study. Int J Oral Maxillofac Implants. 2007;22:383–9.
85.
von Arx T, Hänni S, Jensen SS. Correlation of bone defect dimensions with healing outcome one year after apical surgery. J Endod. 2007;33:1044–8.CrossRef
86.
von Arx T, AlSaeed M. The use of regenerative techniques in apical surgery: a literature review. Saudi Dent J. 2011;23:113–27.CrossRef
87.
Werner S, Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev. 2003;83:835–70.PubMed
88.
89.
90.
Yoshikawa G, Murashima Y, Wadachi R, et al. Guided bone regeneration (GBR) using membrane and calcium sulfate after apicectomy: a comparative histomorphometrical study. Int Endod J. 1991;26:255–63.
Metagegevens
Titel
Guided Tissue Regeneration in Endodontic Surgery: Principle, Efficacy, and Complications
Auteurs
Louis M. Lin, BDS, DMD, PhD
Domenico Ricucci, MD, DDS
Thomas von Arx, Prof. Dr. Med. Dent.
Copyright
2014
Uitgeverij
Springer Berlin Heidelberg
Boek
Complications in Endodontic Surgery

Print ISBN: 978-3-642-54217-6

Elektronisch ISBN: 978-3-642-54218-3

Copyright: 2014

DOI
https://doi.org/10.1007/978-3-642-54218-3_16