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25-04-2017 | Original Article - Design Study Article | Uitgave 6/2017 Open Access

Netherlands Heart Journal 6/2017

Current MitraClip experience, safety and feasibility in the Netherlands

Netherlands Heart Journal > Uitgave 6/2017
Z. Rahhab, F. A. Kortlandt, J. F. Velu, R. A. J. Schurer, V. Delgado, P. Tonino, A. J. Boven, B. J. L. Van den Branden, A. O. Kraaijeveld, M. Voskuil, J. Hoorntje, M. van Wely, K. van Houwelingen, G. B. Bleeker, B. Rensing, I. Kardys, J. Baan jr., J. A. S. Van der Heyden, N. M. Van Mieghem



Data on MitraClip procedural safety and efficacy in the Netherlands are scarce. We aim to provide an overview of the Dutch MitraClip experience.


We pooled anonymised demographic and procedural data of 1151 consecutive MitraClip patients, from 13 Dutch hospitals. Data was collected by product specialists in collaboration with local operators. Effect on mitral regurgitation was intra-procedurally assessed by transoesophageal echocardiography. Technical success and device success were defined according to modified definitions of the Mitral Valve Academic Research Consortium (MVARC).


Median age was 76 (interquartile range 69–82) years and 59% were males. Patients presented with ≥moderate mitral regurgitation and a predominance of functional mitral regurgitation (72%). Overall, 611 (53%) patients were treated with one Clip, 486 (42%) with ≥2 Clips and 54 (5%) received no Clip. The number of patients with ≥2 Clips increased from 22% in 2009 to 52% in 2016. Device success and technical success were 91 and 95%, respectively, and were consistent over the years. Significant reduction of mitral regurgitation by MitraClip was achieved in 94% of patients and was observed more often in patients with functional mitral regurgitation (95% vs. 91%, p = 0.025). Device time declined from 145 min in 2009 to 55 min in 2016.


MitraClip experience in the Netherlands is growing with excellent technical success and device success. Over the years, device time decreased and more patients were treated with ≥2 Clips.

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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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