Skip to main content
Top
Gepubliceerd in: Huisarts en wetenschap 5/2015

01-05-2015 | Onderzoek

COPD-screening bij ouderen heeft weinig effect

Auteurs: dr. Loes Bertens, dr. Johannes Reitsma, Yvonne van Mourik, prof.dr. Jan-Willem Lammers, prof.dr. Karel Moons, prof.dr. Arno Hoes, dr. Frans Rutten

Gepubliceerd in: Huisarts en wetenschap | Uitgave 5/2015

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Samenvatting

Bertens LCM, Reitsma JB, Van Mourik Y, Lammers JWJ, Moons KGM,Hoes AW, Rutten FH. COPD-screening bij ouderen heeft weinig effect.Huisarts Wet 2015;58(5):242-4.

Doel

Nagaan of een screening op COPD bij thuiswonende kwetsbare ouderen met klachten van kortademigheid of verminderd inspanningsvermogen zinvol zou kunnen zijn. Daartoe bepaalden we het medicatiegebruik, het aantal ziekenhuisopnames en de sterfte onder patiënten bij wie de screening leidde tot een eerste diagnose COPD.

Methode

Een panel van deskundigen bepaalde de diagnose op basis van alle screeningsgegevens, inclusief spirometrie. Follow-upgegevens verzamelden we via de deelnemende huisartsen.

Resultaten

De screening werd uitgevoerd bij 386 oudere huisartspatiënten met kortademigheid of inspanningstolerantie. Bij 84 (21,8%) patiënten leidde de screening tot een niet eerder gestelde diagnose COPD. Van deze 84 waren er 15 (17,9%) binnen zes maanden na de diagnose gestart met inhalatiemedicatie of ze hadden hun bestaande medicatie aangepast, en waren er 27 (32,1%) binnen twaalf maanden opgenomen in een ziekenhuis. In de groep bij wie de screening geen COPD had aangetoond, lag dit laatste percentage significant lager (22,9%). De mortaliteit was in beide groepen vergelijkbaar.

Conclusie

Door kwetsbare ouderen te screenen kunnen veel nieuwe gevallen van COPD worden ontdekt. De screening heeft echter weinig consequenties voor de daaropvolgende behandeling. Een mogelijke verklaring is dat patiënten die niet zelf met hun klachten naar de huisarts stappen, waarschijnlijk toch al minder gemotiveerd zijn voor behandeling.
Literatuur
1.
go back to reference Vestbo J, Hurd SS, Agusti AG, Jones PW, Vogelmeier C, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013;187:347–65.CrossRefPubMed Vestbo J, Hurd SS, Agusti AG, Jones PW, Vogelmeier C, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013;187:347–65.CrossRefPubMed
2.
go back to reference Qaseem A, Wilt TJ, Weinberger SE, Hanania NA, Criner G, Van der Molen T, et al. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med 2011;155:179–91.CrossRefPubMed Qaseem A, Wilt TJ, Weinberger SE, Hanania NA, Criner G, Van der Molen T, et al. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med 2011;155:179–91.CrossRefPubMed
3.
go back to reference Swanney MP, Ruppel G, Enright PL, Pedersen OF, Crapo RO, Miller MR, et al. Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction. Thorax 2008;63:1046–51.CrossRefPubMed Swanney MP, Ruppel G, Enright PL, Pedersen OF, Crapo RO, Miller MR, et al. Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction. Thorax 2008;63:1046–51.CrossRefPubMed
4.
go back to reference Schermer TR, Quanjer PH. COPD screening in primary care: who is sick? Prim Care Respir J 2007;16:49–53.CrossRefPubMed Schermer TR, Quanjer PH. COPD screening in primary care: who is sick? Prim Care Respir J 2007;16:49–53.CrossRefPubMed
5.
go back to reference Culver BH. Interpretation of spirometry: we can do better than the GOLD standard. Respir Care 2006;51:719–21.PubMed Culver BH. Interpretation of spirometry: we can do better than the GOLD standard. Respir Care 2006;51:719–21.PubMed
6.
go back to reference Hardie JA, Buist AS, Vollmer WM, Ellingsen I, Bakke PS, Morkve O. Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. Eur Respir J 2002;20:1117–22.CrossRefPubMed Hardie JA, Buist AS, Vollmer WM, Ellingsen I, Bakke PS, Morkve O. Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. Eur Respir J 2002;20:1117–22.CrossRefPubMed
7.
go back to reference Bednarek M, Maciejewski J, Wozniak M, Kuca P, Zielinski J. Prevalence, severity and underdiagnosis of COPD in the primary care setting. Thorax 2008;63:402–7.CrossRefPubMed Bednarek M, Maciejewski J, Wozniak M, Kuca P, Zielinski J. Prevalence, severity and underdiagnosis of COPD in the primary care setting. Thorax 2008;63:402–7.CrossRefPubMed
8.
go back to reference Broekhuizen BD, Sachs AP, Hoes AW, Moons KG, Van den Berg JW, Dalinghaus WH, et al. Undetected chronic obstructive pulmonary disease and asthma in people over 50 years with persistent cough. Br J Gen Pract 2010;60:489–94.CrossRefPubMedCentralPubMed Broekhuizen BD, Sachs AP, Hoes AW, Moons KG, Van den Berg JW, Dalinghaus WH, et al. Undetected chronic obstructive pulmonary disease and asthma in people over 50 years with persistent cough. Br J Gen Pract 2010;60:489–94.CrossRefPubMedCentralPubMed
9.
go back to reference Geijer RM, Sachs AP, Hoes AW, Salome PL, Lammers JW, Verheij TJ. Prevalence of undetected persistent airflow obstruction in male smokers 40-65 years old. Fam Pract 2005;22:485–9.CrossRefPubMed Geijer RM, Sachs AP, Hoes AW, Salome PL, Lammers JW, Verheij TJ. Prevalence of undetected persistent airflow obstruction in male smokers 40-65 years old. Fam Pract 2005;22:485–9.CrossRefPubMed
10.
go back to reference Van Mourik Y, Moons KG, Bertens LC, Reitsma JB, Hoes AW, Rutten FH. Triage of frail elderly with reduced exercise tolerance in primary care (TREE): A clustered randomized diagnostic study. BMC Public Health 2012;12:38–5.CrossRef Van Mourik Y, Moons KG, Bertens LC, Reitsma JB, Hoes AW, Rutten FH. Triage of frail elderly with reduced exercise tolerance in primary care (TREE): A clustered randomized diagnostic study. BMC Public Health 2012;12:38–5.CrossRef
11.
go back to reference Dimopoulou I, Tsintzas OK, Daganou M, Cokkinos DV, Tzelepis GE. Contribution of lung function to exercise capacity in patients with chronic heart failure. Respiration 1999;66:144–9.CrossRefPubMed Dimopoulou I, Tsintzas OK, Daganou M, Cokkinos DV, Tzelepis GE. Contribution of lung function to exercise capacity in patients with chronic heart failure. Respiration 1999;66:144–9.CrossRefPubMed
12.
go back to reference Scarlata S, Pedone C, Fimognari FL, Bellia V, Forastiere F, Incalzi RA. Restrictive pulmonary dysfunction at spirometry and mortality in the elderly. Respir Med 2008;102:1349–54.CrossRefPubMed Scarlata S, Pedone C, Fimognari FL, Bellia V, Forastiere F, Incalzi RA. Restrictive pulmonary dysfunction at spirometry and mortality in the elderly. Respir Med 2008;102:1349–54.CrossRefPubMed
13.
go back to reference Faggiano P. Abnormalities of pulmonary function in congestive heart failure. Int J Cardiol 1994;44:1–8.CrossRefPubMed Faggiano P. Abnormalities of pulmonary function in congestive heart failure. Int J Cardiol 1994;44:1–8.CrossRefPubMed
14.
go back to reference Güder G, Rutten FH, Brenner S, Angermann CE, Berliner D, Ertl G, et al. The impact of heart failure on the classification of COPD severity. J Card Fail 2012;18:637–44.CrossRefPubMed Güder G, Rutten FH, Brenner S, Angermann CE, Berliner D, Ertl G, et al. The impact of heart failure on the classification of COPD severity. J Card Fail 2012;18:637–44.CrossRefPubMed
15.
go back to reference Guerra S, Sherrill DL, Venker C, Ceccato CM, Halonen M, Martinez FD. Morbidity and mortality associated with the restrictive spirometric pattern: a longitudinal study. Thorax 2010;65:499–504.CrossRefPubMedCentralPubMed Guerra S, Sherrill DL, Venker C, Ceccato CM, Halonen M, Martinez FD. Morbidity and mortality associated with the restrictive spirometric pattern: a longitudinal study. Thorax 2010;65:499–504.CrossRefPubMedCentralPubMed
1.
go back to reference Vestbo J, Hurd SS, Agusti AG, Jones PW, Vogelmeier C, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013;187:347–65.CrossRefPubMed Vestbo J, Hurd SS, Agusti AG, Jones PW, Vogelmeier C, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013;187:347–65.CrossRefPubMed
2.
go back to reference Qaseem A, Wilt TJ, Weinberger SE, Hanania NA, Criner G, Van der Molen T, et al. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med 2011;155:179–91.CrossRefPubMed Qaseem A, Wilt TJ, Weinberger SE, Hanania NA, Criner G, Van der Molen T, et al. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med 2011;155:179–91.CrossRefPubMed
3.
go back to reference Swanney MP, Ruppel G, Enright PL, Pedersen OF, Crapo RO, Miller MR, et al. Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction. Thorax 2008;63:1046–51.CrossRefPubMed Swanney MP, Ruppel G, Enright PL, Pedersen OF, Crapo RO, Miller MR, et al. Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction. Thorax 2008;63:1046–51.CrossRefPubMed
4.
go back to reference Schermer TR, Quanjer PH. COPD screening in primary care: who is sick? Prim Care Respir J 2007;16:49–53.CrossRefPubMed Schermer TR, Quanjer PH. COPD screening in primary care: who is sick? Prim Care Respir J 2007;16:49–53.CrossRefPubMed
5.
go back to reference Culver BH. Interpretation of spirometry: we can do better than the GOLD standard. Respir Care 2006;51:719–21.PubMed Culver BH. Interpretation of spirometry: we can do better than the GOLD standard. Respir Care 2006;51:719–21.PubMed
6.
go back to reference Hardie JA, Buist AS, Vollmer WM, Ellingsen I, Bakke PS, Morkve O. Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. Eur Respir J 2002;20:1117–22.CrossRefPubMed Hardie JA, Buist AS, Vollmer WM, Ellingsen I, Bakke PS, Morkve O. Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. Eur Respir J 2002;20:1117–22.CrossRefPubMed
7.
go back to reference Bednarek M, Maciejewski J, Wozniak M, Kuca P, Zielinski J. Prevalence, severity and underdiagnosis of COPD in the primary care setting. Thorax 2008;63:402–7.CrossRefPubMed Bednarek M, Maciejewski J, Wozniak M, Kuca P, Zielinski J. Prevalence, severity and underdiagnosis of COPD in the primary care setting. Thorax 2008;63:402–7.CrossRefPubMed
8.
go back to reference Broekhuizen BD, Sachs AP, Hoes AW, Moons KG, Van den Berg JW, Dalinghaus WH, et al. Undetected chronic obstructive pulmonary disease and asthma in people over 50 years with persistent cough. Br J Gen Pract 2010;60:489–94.CrossRefPubMedCentralPubMed Broekhuizen BD, Sachs AP, Hoes AW, Moons KG, Van den Berg JW, Dalinghaus WH, et al. Undetected chronic obstructive pulmonary disease and asthma in people over 50 years with persistent cough. Br J Gen Pract 2010;60:489–94.CrossRefPubMedCentralPubMed
9.
go back to reference Geijer RM, Sachs AP, Hoes AW, Salome PL, Lammers JW, Verheij TJ. Prevalence of undetected persistent airflow obstruction in male smokers 40-65 years old. Fam Pract 2005;22:485–9.CrossRefPubMed Geijer RM, Sachs AP, Hoes AW, Salome PL, Lammers JW, Verheij TJ. Prevalence of undetected persistent airflow obstruction in male smokers 40-65 years old. Fam Pract 2005;22:485–9.CrossRefPubMed
10.
go back to reference Van Mourik Y, Moons KG, Bertens LC, Reitsma JB, Hoes AW, Rutten FH. Triage of frail elderly with reduced exercise tolerance in primary care (TREE): A clustered randomized diagnostic study. BMC Public Health 2012;12:38–5.CrossRef Van Mourik Y, Moons KG, Bertens LC, Reitsma JB, Hoes AW, Rutten FH. Triage of frail elderly with reduced exercise tolerance in primary care (TREE): A clustered randomized diagnostic study. BMC Public Health 2012;12:38–5.CrossRef
11.
go back to reference Dimopoulou I, Tsintzas OK, Daganou M, Cokkinos DV, Tzelepis GE. Contribution of lung function to exercise capacity in patients with chronic heart failure. Respiration 1999;66:144–9.CrossRefPubMed Dimopoulou I, Tsintzas OK, Daganou M, Cokkinos DV, Tzelepis GE. Contribution of lung function to exercise capacity in patients with chronic heart failure. Respiration 1999;66:144–9.CrossRefPubMed
12.
go back to reference Scarlata S, Pedone C, Fimognari FL, Bellia V, Forastiere F, Incalzi RA. Restrictive pulmonary dysfunction at spirometry and mortality in the elderly. Respir Med 2008;102:1349–54.CrossRefPubMed Scarlata S, Pedone C, Fimognari FL, Bellia V, Forastiere F, Incalzi RA. Restrictive pulmonary dysfunction at spirometry and mortality in the elderly. Respir Med 2008;102:1349–54.CrossRefPubMed
13.
go back to reference Faggiano P. Abnormalities of pulmonary function in congestive heart failure. Int J Cardiol 1994;44:1–8.CrossRefPubMed Faggiano P. Abnormalities of pulmonary function in congestive heart failure. Int J Cardiol 1994;44:1–8.CrossRefPubMed
14.
go back to reference Güder G, Rutten FH, Brenner S, Angermann CE, Berliner D, Ertl G, et al. The impact of heart failure on the classification of COPD severity. J Card Fail 2012;18:637–44.CrossRefPubMed Güder G, Rutten FH, Brenner S, Angermann CE, Berliner D, Ertl G, et al. The impact of heart failure on the classification of COPD severity. J Card Fail 2012;18:637–44.CrossRefPubMed
15.
go back to reference Guerra S, Sherrill DL, Venker C, Ceccato CM, Halonen M, Martinez FD. Morbidity and mortality associated with the restrictive spirometric pattern: a longitudinal study. Thorax 2010;65:499–504.CrossRefPubMedCentralPubMed Guerra S, Sherrill DL, Venker C, Ceccato CM, Halonen M, Martinez FD. Morbidity and mortality associated with the restrictive spirometric pattern: a longitudinal study. Thorax 2010;65:499–504.CrossRefPubMedCentralPubMed
Metagegevens
Titel
COPD-screening bij ouderen heeft weinig effect
Auteurs
dr. Loes Bertens
dr. Johannes Reitsma
Yvonne van Mourik
prof.dr. Jan-Willem Lammers
prof.dr. Karel Moons
prof.dr. Arno Hoes
dr. Frans Rutten
Publicatiedatum
01-05-2015
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Huisarts en wetenschap / Uitgave 5/2015
Print ISSN: 0018-7070
Elektronisch ISSN: 1876-5912
DOI
https://doi.org/10.1007/s12445-015-0131-4

Andere artikelen Uitgave 5/2015

Huisarts en wetenschap 5/2015 Naar de uitgave