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Gepubliceerd in: Netherlands Heart Journal 2/2008

01-02-2008 | Original article

Contrast-enhanced versus non-enhanced three-dimensional echocardiography of left ventricular volumes

Gepubliceerd in: Netherlands Heart Journal | Uitgave 2/2008

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Abstract

Background In three-dimensional echocardiography (3DE), individual endocardial trabeculae are not clearly visible necessitating left ventricular (LV) volumes to be measured by tracing the innermost endocardial contour. Ultrasound contrast agents aim to improve endocardial definition, but may delineate the outermost endocardial contour by filling up intertrabecular space. Although measurement reproducibility may benefit, there may be a significant influence on absolute LV volume measurements.
Methods Twenty patients with a recent myocardial infarction and good ultrasound image quality underwent 3DE using the TomTec Freehand method before and during continuous intravenous contrast infusion. LV volumes were measured offline using TomTec Echo-Scan software.
Results The use of contrast enhancement increased end-diastolic (110±35 vs. 144±53 ml; p<0.01) and end-systolic volume measurements (68±31 vs. 87±45 ml; p<0.01) significantly compared with non-contrast; the ejection fraction remained unchanged (40±13 vs. 41±14%, p=NS). Measurement reproducibility did not improve significantly, however.
Conclusion Volumes measured by 3DE are significantly larger when ultrasound contrast is used. Possibly, intertrabecular space comprises a substantial part of the LV cavity. In the presence of an adequate apical acoustic window, ultrasound contrast does not improve LV volume measurement reproducibility. (Neth Heart J 2008;16:47-52.)
Literatuur
1.
go back to reference Starling MR, Crawford MH, Sorensen SG, Levi B, Richards KL, O’Rourke RA. Comparative accuracy of apical biplane crosssectional echocardiography and gated equilibrium radionuclide angiography for estimating left ventricular size and performance. Circulation 1981;63:1075-84. Starling MR, Crawford MH, Sorensen SG, Levi B, Richards KL, O’Rourke RA. Comparative accuracy of apical biplane crosssectional echocardiography and gated equilibrium radionuclide angiography for estimating left ventricular size and performance. Circulation 1981;63:1075-84.
2.
go back to reference Bellenger NG, Burgess MI, Ray SG, Lahiri A, Coats AJ, Cleland JG, et al. Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance; are they interchangeable? Eur Heart J 2000;21:1387-96. Bellenger NG, Burgess MI, Ray SG, Lahiri A, Coats AJ, Cleland JG, et al. Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance; are they interchangeable? Eur Heart J 2000;21:1387-96.
3.
go back to reference Pattynama PM, De Roos A, Van der Wall EE, Van Voorthuisen AE. Evaluation of cardiac function with magnetic resonance imaging. Am Heart J 1994;128:595-607. Pattynama PM, De Roos A, Van der Wall EE, Van Voorthuisen AE. Evaluation of cardiac function with magnetic resonance imaging. Am Heart J 1994;128:595-607.
4.
go back to reference Lee D, Fuisz AR, Fan PH, Hsu TL, Liu CP, Chiang HT. Realtime 3-dimensional echocardiographic evaluation of left ventricular volume: correlation with magnetic resonance imaging–a validation study. J Am Soc Echocardiogr 2001;14:1001-9. Lee D, Fuisz AR, Fan PH, Hsu TL, Liu CP, Chiang HT. Realtime 3-dimensional echocardiographic evaluation of left ventricular volume: correlation with magnetic resonance imaging–a validation study. J Am Soc Echocardiogr 2001;14:1001-9.
5.
go back to reference Kim WY, Sogaard P, Kristensen BO, Egeblad H. Measurement of left ventricular volumes by 3-dimensional echocardiography with tissue harmonic imaging: a comparison with magnetic resonance imaging. J Am Soc Echocardiogr 2001;14:169-79. Kim WY, Sogaard P, Kristensen BO, Egeblad H. Measurement of left ventricular volumes by 3-dimensional echocardiography with tissue harmonic imaging: a comparison with magnetic resonance imaging. J Am Soc Echocardiogr 2001;14:169-79.
6.
go back to reference Schmidt MA, Ohazama CJ, Agyeman KO, Freidlin RZ, Jones M, Laurienzo JM, et al. Real-time three-dimensional echocardiography for measurement of left ventricular volumes. Am J Cardiol 1999;84:1434-9. Schmidt MA, Ohazama CJ, Agyeman KO, Freidlin RZ, Jones M, Laurienzo JM, et al. Real-time three-dimensional echocardiography for measurement of left ventricular volumes. Am J Cardiol 1999;84:1434-9.
7.
go back to reference Shiota T, McCarthy PM, White RD, Qin JX, Greenberg NL, Flamm SD, et al. Initial clinical experience of real-time threedimensional echocardiography in patients with ischemic and idiopathic dilated cardiomyopathy. Am J Cardiol 1999;84:1068-73. Shiota T, McCarthy PM, White RD, Qin JX, Greenberg NL, Flamm SD, et al. Initial clinical experience of real-time threedimensional echocardiography in patients with ischemic and idiopathic dilated cardiomyopathy. Am J Cardiol 1999;84:1068-73.
8.
go back to reference Nosir YF, Stoker J, Kasprzak JD, Lequin MH, Dall’Agata A, Ten Cate FJ, et al. Paraplane analysis from precordial three-dimensional echocardiographic data sets for rapid and accurate quantification of left ventricular volume and function: a comparison with magnetic resonance imaging. Am.Heart J 1999;137:134-43. Nosir YF, Stoker J, Kasprzak JD, Lequin MH, Dall’Agata A, Ten Cate FJ, et al. Paraplane analysis from precordial three-dimensional echocardiographic data sets for rapid and accurate quantification of left ventricular volume and function: a comparison with magnetic resonance imaging. Am.Heart J 1999;137:134-43.
9.
go back to reference Buck T, Hunold P, Wentz KU, Tkalec W, Nesser HJ, Erbel R. Tomographic three-dimensional echocardiographic determination of chamber size and systolic function in patients with left ventricular aneurysm: comparison to magnetic resonance imaging, cineventriculography, and two-dimensional echocardiography. Circulation 1997;96:4286-97. Buck T, Hunold P, Wentz KU, Tkalec W, Nesser HJ, Erbel R. Tomographic three-dimensional echocardiographic determination of chamber size and systolic function in patients with left ventricular aneurysm: comparison to magnetic resonance imaging, cineventriculography, and two-dimensional echocardiography. Circulation 1997;96:4286-97.
10.
go back to reference Gopal AS, Schnellbaecher MJ, Shen Z, Boxt LM, Katz J, King DL. Freehand three-dimensional echocardiography for determination of left ventricular volume and mass in patients with abnormal ventricles: comparison with magnetic resonance imaging. J Am Soc Echocardiogr 1997;10:853-61. Gopal AS, Schnellbaecher MJ, Shen Z, Boxt LM, Katz J, King DL. Freehand three-dimensional echocardiography for determination of left ventricular volume and mass in patients with abnormal ventricles: comparison with magnetic resonance imaging. J Am Soc Echocardiogr 1997;10:853-61.
11.
go back to reference De Castro S, Agati L, Cartoni D, Papetti F, Beni S, Adorisio R, et al. Harmonic imaging with Levovist for transthoracic echocardiographic reconstruction of left ventricle in patients with postischemic left ventricular dysfunction and suboptimal acoustic windows. J Am Soc Echocardiogr 2000;13:139-45. De Castro S, Agati L, Cartoni D, Papetti F, Beni S, Adorisio R, et al. Harmonic imaging with Levovist for transthoracic echocardiographic reconstruction of left ventricle in patients with postischemic left ventricular dysfunction and suboptimal acoustic windows. J Am Soc Echocardiogr 2000;13:139-45.
12.
go back to reference Crouse LJ, Cheirif J, Hanly DE, Kisslo JA, Labovitz AJ, Raichlen JS, et al. Opacification and border delineation improvement in patients with suboptimal endocardial border definition in routine echocardiography: results of the Phase III Albunex Multicenter Trial. J Am Coll Cardiol 1993;22:1494-500. Crouse LJ, Cheirif J, Hanly DE, Kisslo JA, Labovitz AJ, Raichlen JS, et al. Opacification and border delineation improvement in patients with suboptimal endocardial border definition in routine echocardiography: results of the Phase III Albunex Multicenter Trial. J Am Coll Cardiol 1993;22:1494-500.
13.
go back to reference Lindner JR, Dent JM, Moos SP, Jayaweera AR, Kaul S. Enhancement of left ventricular cavity opacification by harmonic imaging after venous injection of Albunex. Am J Cardiol 1997;79:1657-62. Lindner JR, Dent JM, Moos SP, Jayaweera AR, Kaul S. Enhancement of left ventricular cavity opacification by harmonic imaging after venous injection of Albunex. Am J Cardiol 1997;79:1657-62.
14.
go back to reference Grayburn PA, Weiss JL, Hack TC, Klodas E, Raichlen JS, Vannan MA, et al. Phase III multicenter trial comparing the efficacy of 2% dodecafluoropentane emulsion (EchoGen) and sonicated 5% human albumin (Albunex) as ultrasound contrast agents in patients with suboptimal echocardiograms. J Am Coll Cardiol 1998;32:230-6. Grayburn PA, Weiss JL, Hack TC, Klodas E, Raichlen JS, Vannan MA, et al. Phase III multicenter trial comparing the efficacy of 2% dodecafluoropentane emulsion (EchoGen) and sonicated 5% human albumin (Albunex) as ultrasound contrast agents in patients with suboptimal echocardiograms. J Am Coll Cardiol 1998;32:230-6.
15.
go back to reference Cohen JL, Cheirif J, Segar DS, Gillam LD, Gottdiener JS, Hausnerova E, et al. Improved left ventricular endocardial border delineation and opacification with OPTISON (FS069), a new echocardiographic contrast agent. Results of a phase III Multicenter Trial. J Am Coll Cardiol 1998;32:746-52. Cohen JL, Cheirif J, Segar DS, Gillam LD, Gottdiener JS, Hausnerova E, et al. Improved left ventricular endocardial border delineation and opacification with OPTISON (FS069), a new echocardiographic contrast agent. Results of a phase III Multicenter Trial. J Am Coll Cardiol 1998;32:746-52.
16.
go back to reference Kasprzak JD, Paelinck B, Ten Cate FJ, Vletter WB, de Jong N, Poldermans D, et al. Comparison of native and contrast-enhanced harmonic echocardiography for visualization of left ventricular endocardial border. Am J Cardiol 1999;83:211-7. Kasprzak JD, Paelinck B, Ten Cate FJ, Vletter WB, de Jong N, Poldermans D, et al. Comparison of native and contrast-enhanced harmonic echocardiography for visualization of left ventricular endocardial border. Am J Cardiol 1999;83:211-7.
17.
go back to reference Lafitte S, Dos SP, Kerouani A, Robhan T, Roudaut R. Improved reliability for echocardiographic measurement of left ventricular volume using harmonic power imaging mode combined with contrast agent. Am J Cardiol 2000;85:1234-8. Lafitte S, Dos SP, Kerouani A, Robhan T, Roudaut R. Improved reliability for echocardiographic measurement of left ventricular volume using harmonic power imaging mode combined with contrast agent. Am J Cardiol 2000;85:1234-8.
18.
go back to reference Ota T, Kisslo J, von Ramm OT, Yoshikawa J. Real-time, volumetric echocardiography: usefulness of volumetric scanning for the assessment of cardiac volume and function. J Cardiol 2001;37(Suppl 1):93-101. Ota T, Kisslo J, von Ramm OT, Yoshikawa J. Real-time, volumetric echocardiography: usefulness of volumetric scanning for the assessment of cardiac volume and function. J Cardiol 2001;37(Suppl 1):93-101.
19.
go back to reference Hirooka K, Yasumura Y, Tsujita Y, Hanatani A, Nakatani S, Miyatake K, et al. An enhanced method for left ventricular volume and ejection fraction by triggered harmonic contrast echocardiography. Int J Card Imaging 2001;17:253-61. Hirooka K, Yasumura Y, Tsujita Y, Hanatani A, Nakatani S, Miyatake K, et al. An enhanced method for left ventricular volume and ejection fraction by triggered harmonic contrast echocardiography. Int J Card Imaging 2001;17:253-61.
20.
go back to reference Hundley WG, Kizilbash AM, Afridi I, Franco F, Peshock RM, Grayburn PA. Administration of an intravenous perfluorocarbon contrast agent improves echocardiographic determination of left ventricular volumes and ejection fraction: comparison with cine magnetic resonance imaging. J Am Coll Cardiol 1998;32:1426-32. Hundley WG, Kizilbash AM, Afridi I, Franco F, Peshock RM, Grayburn PA. Administration of an intravenous perfluorocarbon contrast agent improves echocardiographic determination of left ventricular volumes and ejection fraction: comparison with cine magnetic resonance imaging. J Am Coll Cardiol 1998;32:1426-32.
21.
go back to reference Zotz RJ, Genth S, Waaler A, Erbel R, Meyer J. Left ventricular volume determination using Albunex. J Am Soc Echocardiogr 1996;9:1-8. Zotz RJ, Genth S, Waaler A, Erbel R, Meyer J. Left ventricular volume determination using Albunex. J Am Soc Echocardiogr 1996;9:1-8.
22.
go back to reference Hoffmann R, von Bardeleben S, Ten Cate F, et al. Assessment of systolic left ventricular function: a multi-centre comparison of cineventriculography, cardiac magnetic resonance imaging, unenhanced and contrast-enhanced echocardiography. Eur Heart J 2005;26:607-16. Hoffmann R, von Bardeleben S, Ten Cate F, et al. Assessment of systolic left ventricular function: a multi-centre comparison of cineventriculography, cardiac magnetic resonance imaging, unenhanced and contrast-enhanced echocardiography. Eur Heart J 2005;26:607-16.
23.
go back to reference Mannaerts HF, Van Der Heide JA, Kamp O, Papavassiliu T, Marcus JT, Beek A, et al. Quantification of left ventricular volumes and ejection fraction using freehand transthoracic three-dimensional echocardiography: Comparison with magnetic resonance imaging. J Am Soc Echocardiogr 2003;16:101-9. Mannaerts HF, Van Der Heide JA, Kamp O, Papavassiliu T, Marcus JT, Beek A, et al. Quantification of left ventricular volumes and ejection fraction using freehand transthoracic three-dimensional echocardiography: Comparison with magnetic resonance imaging. J Am Soc Echocardiogr 2003;16:101-9.
24.
go back to reference Miller JJ, Tiemann K, Podell S, Doerr Stevens JK, Kuvelas T, Greener Y, et al. In vitro, animal, and human characterization of OPTISON infusions for myocardial contrast echocardiography. J Am Soc Echocardiogr 1999;12:1027-34. Miller JJ, Tiemann K, Podell S, Doerr Stevens JK, Kuvelas T, Greener Y, et al. In vitro, animal, and human characterization of OPTISON infusions for myocardial contrast echocardiography. J Am Soc Echocardiogr 1999;12:1027-34.
25.
go back to reference Daniel GK, Chawla MK, Sawada SG, Gradus-Pizlo I, Feigenbaum H, Segar DS. Echocardiographic imaging of technically difficult patients in the intensive care unit: use of optison in combination with fundamental and harmonic imaging. J Am Soc Echocardiogr 2001;14:917-20. Daniel GK, Chawla MK, Sawada SG, Gradus-Pizlo I, Feigenbaum H, Segar DS. Echocardiographic imaging of technically difficult patients in the intensive care unit: use of optison in combination with fundamental and harmonic imaging. J Am Soc Echocardiogr 2001;14:917-20.
26.
go back to reference Papavassiliu T, Kuhl HP, Schroder M, Suselbeck T, Bondarenko O, Bohm CK, et al. Effect of endocardial trabeculae on left ventricular measurements and measurement reproducibility at cardiovascular MR imaging. Radiology 2005;236:57-64. Papavassiliu T, Kuhl HP, Schroder M, Suselbeck T, Bondarenko O, Bohm CK, et al. Effect of endocardial trabeculae on left ventricular measurements and measurement reproducibility at cardiovascular MR imaging. Radiology 2005;236:57-64.
27.
go back to reference Kuhl HP, Schreckenberg M, Rulands D, Katoh M, Schafer W, Schummers G, et al. High-resolution transthoracic real-time threedimensional echocardiography. Quantitation of cardiac volumes and function using semi-automated border detection and comparison with cardiac magnetic resonance. J Am Coll Cardiol 2004;43:2083-90. Kuhl HP, Schreckenberg M, Rulands D, Katoh M, Schafer W, Schummers G, et al. High-resolution transthoracic real-time threedimensional echocardiography. Quantitation of cardiac volumes and function using semi-automated border detection and comparison with cardiac magnetic resonance. J Am Coll Cardiol 2004;43:2083-90.
Metagegevens
Titel
Contrast-enhanced versus non-enhanced three-dimensional echocardiography of left ventricular volumes
Publicatiedatum
01-02-2008
Gepubliceerd in
Netherlands Heart Journal / Uitgave 2/2008
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03086117

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