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Quality of Life Research
Gepubliceerd in: Quality of Life Research 8/2022

25-01-2022

Clinical utility of PTSD, resilience, sleep, and blast as risk factors to predict poor neurobehavioral functioning following traumatic brain injury: A longitudinal study in U.S. military service members

Auteurs: Rael T. Lange, Louis M. French, Jason M. Bailie, Victoria C. Merritt, Cassandra L. Pattinson, Lars D. Hungerford, Sara. M. Lippa, Tracey A. Brickell

Gepubliceerd in: Quality of Life Research | Uitgave 8/2022

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Abstract

Purpose

This study examined the clinical utility of post-traumatic stress disorder (PTSD), low resilience, poor sleep, and lifetime blast exposure as risk factors for predicting future neurobehavioral outcome following traumatic brain injury (TBI).

Methods

Participants were 591 U.S. military service members and veterans who had sustained a TBI (n = 419) or orthopedic injury without TBI (n = 172). Participants completed the Neurobehavioral Symptom Inventory, PTSD Checklist, and the TBI-Quality of Life (TBI-QOL) scale at baseline and follow-up.

Results

Using the four risk factors at baseline, 15 risk factor combinations were examined by calculating odds ratios to predict poor neurobehavioral outcome at follow-up (i.e., number of abnormal scores across five TBI-QOL scales [e.g., Fatigue, Depression]). The vast majority of risk factor combinations resulted in odds ratios that were considered to be clinically meaningful (i.e., ≥ 2.5) for predicting poor outcome. The risk factor combinations with the highest odds ratios included PTSD singularly, or in combination with poor sleep and/or low resilience (odds ratios = 4.3–72.4). However, poor sleep and low resilience were also strong predictors in the absence of PTSD (odds ratios = 3.1–29.8).

Conclusion

PTSD, poor sleep, and low resilience, singularly or in combination, may be valuable risk factors that can be used clinically for targeted early interventions.
vorige artikel Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study
volgende artikel Coping strategies and quality of life in patients with chronic symptoms visiting a Lyme Center in a Dutch teaching hospital
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Metagegevens
Titel
Clinical utility of PTSD, resilience, sleep, and blast as risk factors to predict poor neurobehavioral functioning following traumatic brain injury: A longitudinal study in U.S. military service members
Auteurs
Rael T. Lange
Louis M. French
Jason M. Bailie
Victoria C. Merritt
Cassandra L. Pattinson
Lars D. Hungerford
Sara. M. Lippa
Tracey A. Brickell
Publicatiedatum
25-01-2022
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 8/2022
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-022-03092-4

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