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Gepubliceerd in: Journal of Autism and Developmental Disorders 11/2011

01-11-2011 | Letter to the Editor

c-Kit+ Cells Transplantation as a New Treatment for Autism, a Novel Hypothesis with Important Research and Clinical Implication

Auteur: Ahmad Ghanizadeh

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2011

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Excerpt

The excitatory amino acid neurotransmitter of Glutamate has a major role in the brain. However, it has a balance. Excess glutamate is neurotoxic. Glutamate transporters control the level of glutamate in synaptic space. There are different types of glutamate transporters. One of the transporters is GLT-1, which is distributed throughout different brain regions and spinal cord, and which is not present in the white matter (Maragakis and Rothstein 2001). GLT-1 has an important role for removal of glutamate (Danbolt 2001; Robinson 1998). In order to prevent excitotoxicity, these transporters keep glutamate synaptic concentrations low. …
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Metagegevens
Titel
c-Kit+ Cells Transplantation as a New Treatment for Autism, a Novel Hypothesis with Important Research and Clinical Implication
Auteur
Ahmad Ghanizadeh
Publicatiedatum
01-11-2011
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 11/2011
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-010-1174-9

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