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01-06-2009

Are gender-associated differences in quality of life in colorectal cancer patients disease-specific?

Auteurs: Johannes Giesinger, Georg Kemmler, Verena Mueller, August Zabernigg, Beate Mayrbaeurl, Josef Thaler, Dietmar Öfner, Christian Pegger, Gerhard Rumpold, Barbara Weber, Barbara Sperner-Unterweger, Bernhard Holzner

Gepubliceerd in: Quality of Life Research | Uitgave 5/2009

Abstract

Purpose

The purpose of this study was to investigate gender-associated differences in quality of life in colorectal cancer patients and compare such differences to the general population.

Methods

Colorectal cancer patients attending three oncological centres in Austria were consecutively recruited and assessed with the EORTC QLQ-C30. For the purpose of comparison, a gender- and age-matched healthy control group was drawn from a representative sample of the Austrian general population.

Results

About 206 patients (47.1% women; mean age 64.8 years) with colorectal cancer were included and compared with 206 persons from the general population. A two-way analysis of variance showed significant main effects (gender and colorectal cancer vs. healthy) for most EORTC QLQ-C30 scales, but a significant interaction effect was only found for diarrhea. This means that gender-associated differences specific for colorectal cancer patients were only found for diarrhea.

Conclusion

The vast majority of studies on gender-associated differences in quality of life compare male and female oncological patients and neglect the issue of the disease-specificity of such differences. Our study revealed that women and men suffering from colorectal cancer scored differently across many aspects of quality of life, but with the exception of diarrhea, these differences were also found in the general population, i.e. they indicated no gender-specific reaction to disease.

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Titel: Are gender-associated differences in quality of life in colorectal cancer patients disease-specific?
Auteurs: Johannes Giesinger
Georg Kemmler
Verena Mueller
August Zabernigg
Beate Mayrbaeurl
Josef Thaler
Dietmar Öfner
Christian Pegger
Gerhard Rumpold
Barbara Weber
Barbara Sperner-Unterweger
Bernhard Holzner
Publicatiedatum: 01-06-2009
Uitgeverij: Springer Netherlands
Gepubliceerd in: Quality of Life Research / Uitgave 5/2009
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-009-9468-0

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Abstract

Purpose

Methods

Results

Conclusion

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