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10-03-2023

A national survey of Iranian general population to estimate a value set for the EQ-5D-5L

Auteurs: Somayeh Afshari, Rajabali Daroudi, Reza Goudarzi, Alireza Mahboub–Ahari, Mehdi Yaseri, Ali Akbari Sari, Hosein Ameri, Sajjad Bahariniya, Alireza Oliaei-Manesh, Khalil Kalavani, Zahra Zare, Elham Hasannezhad, Mohammadamin Mirzaei, Zahra Amiri

Gepubliceerd in: Quality of Life Research | Uitgave 7/2023

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Abstract

Objectives

The main aim of this study is to estimate a national value set of the EQ-5D-5L questionnaire for Iran.

Methods

The composite time trade-off (cTTO) and discrete choice experiment (DCE) methods; and the protocol for EuroQol Portable Valuation Technology (EQ-PVT) were used to estimate the Iran national value set. 1179 face-to-face computer-assisted interviews were conducted with adults that were recruited from five Iran major cities in 2021. Generalized least squares, Tobit, heteroskedastic, logit, and hybrid models were used to analyze the data and to identify the best fitting model.

Results

According to the logical consistency of the parameters, significance levels and prediction accuracy indices of the MAE; a heteroscedastic censored Tobit hybrid model combining cTTO and DCE responses was considered as the best fitting model to estimate the final value set. The predicted values ranged from − 1.19 for the worst health state (55555) to 1 for full health (11111), with 53.6% of the predicted values being negative. Mobility was the most influential dimension on health state preference values.

Conclusions

The present study estimated a national EQ-5D-5L value set for Iranian policy makers and researchers. The value set enables the EQ-5D-5L questionnaire to use to calculate QALYs to assist the priority setting and efficient allocation of limited healthcare resources.
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Literatuur
1.
go back to reference Health NIf, Excellence C. Methods for the development of NICE public health guidance: National Institute for Health and Care Excellence. 2012. Health NIf, Excellence C. Methods for the development of NICE public health guidance: National Institute for Health and Care Excellence. 2012.
2.
go back to reference Weinstein, M. C., Torrance, G., & McGuire, A. (2009). QALYs: The basics. Value In Health, 12, S5–S9.CrossRefPubMed Weinstein, M. C., Torrance, G., & McGuire, A. (2009). QALYs: The basics. Value In Health, 12, S5–S9.CrossRefPubMed
3.
go back to reference Brooks R, Group E. (1996). EuroQol: The current state of play. Health Policy, 37(1), 53–72.CrossRef Brooks R, Group E. (1996). EuroQol: The current state of play. Health Policy, 37(1), 53–72.CrossRef
4.
go back to reference Brazier, J., Roberts, J., & Deverill, M. (2002). The estimation of a preference-based measure of health from the SF-36. Journal of Health Economics, 21(2), 271–292.CrossRefPubMed Brazier, J., Roberts, J., & Deverill, M. (2002). The estimation of a preference-based measure of health from the SF-36. Journal of Health Economics, 21(2), 271–292.CrossRefPubMed
5.
go back to reference Feeny, D., Furlong, W., Torrance, G. W., Goldsmith, C. H., Zhu, Z., DePauw, S., et al. (2002). Multiattribute and single-attribute utility functions for the health utilities index mark 3 system. Medical Care, 40(2), 113–128.CrossRefPubMed Feeny, D., Furlong, W., Torrance, G. W., Goldsmith, C. H., Zhu, Z., DePauw, S., et al. (2002). Multiattribute and single-attribute utility functions for the health utilities index mark 3 system. Medical Care, 40(2), 113–128.CrossRefPubMed
6.
go back to reference Herdman, M., Gudex, C., Lloyd, A., Janssen, M., Kind, P., Parkin, D., et al. (2011). Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Quality of Life Research, 20(10), 1727–1736.CrossRefPubMedPubMedCentral Herdman, M., Gudex, C., Lloyd, A., Janssen, M., Kind, P., Parkin, D., et al. (2011). Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Quality of Life Research, 20(10), 1727–1736.CrossRefPubMedPubMedCentral
7.
go back to reference Kennedy-Martin, M., Slaap, B., Herdman, M., van Reenen, M., Kennedy-Martin, T., Greiner, W., et al. (2020). Which multi-attribute utility instruments are recommended for use in cost-utility analysis? A review of national health technology assessment (HTA) guidelines. The European Journal of Health Economics, 21(8), 1245–1257.CrossRefPubMedPubMedCentral Kennedy-Martin, M., Slaap, B., Herdman, M., van Reenen, M., Kennedy-Martin, T., Greiner, W., et al. (2020). Which multi-attribute utility instruments are recommended for use in cost-utility analysis? A review of national health technology assessment (HTA) guidelines. The European Journal of Health Economics, 21(8), 1245–1257.CrossRefPubMedPubMedCentral
8.
go back to reference Buchholz, I., Janssen, M. F., Kohlmann, T., & Feng, Y.-S. (2018). A systematic review of studies comparing the measurement properties of the three-level and five-level versions of the EQ-5D. PharmacoEconomics, 36(6), 645–661.CrossRefPubMedPubMedCentral Buchholz, I., Janssen, M. F., Kohlmann, T., & Feng, Y.-S. (2018). A systematic review of studies comparing the measurement properties of the three-level and five-level versions of the EQ-5D. PharmacoEconomics, 36(6), 645–661.CrossRefPubMedPubMedCentral
9.
go back to reference Yousefi, M., Nahvijou, A., Sari, A. A., & Ameri, H. (2021). Mapping QLQ-C30 onto EQ-5D-5L and SF-6D-V2 in patients with colorectal and breast cancer from a developing country. Value in Health Regional Issues, 24, 57–66.CrossRefPubMed Yousefi, M., Nahvijou, A., Sari, A. A., & Ameri, H. (2021). Mapping QLQ-C30 onto EQ-5D-5L and SF-6D-V2 in patients with colorectal and breast cancer from a developing country. Value in Health Regional Issues, 24, 57–66.CrossRefPubMed
10.
go back to reference Atfannezhad, M., Sharifi, M., Madadizadeh, F., & Ameri, H. (2022). Utility values in colorectal cancer patients treated with chemotherapy. Cancer Investigation, 40(1), 46–54.CrossRefPubMed Atfannezhad, M., Sharifi, M., Madadizadeh, F., & Ameri, H. (2022). Utility values in colorectal cancer patients treated with chemotherapy. Cancer Investigation, 40(1), 46–54.CrossRefPubMed
11.
go back to reference Yousefi, M., Safari, H., Akbari Sari, A., Raei, B., & Ameri, H. (2019). Assessing the performance of direct and indirect utility eliciting methods in patients with colorectal cancer: EQ-5D-5L versus C-TTO. Health Services and Outcomes Research Methodology, 19(4), 259–270.CrossRef Yousefi, M., Safari, H., Akbari Sari, A., Raei, B., & Ameri, H. (2019). Assessing the performance of direct and indirect utility eliciting methods in patients with colorectal cancer: EQ-5D-5L versus C-TTO. Health Services and Outcomes Research Methodology, 19(4), 259–270.CrossRef
12.
go back to reference Nahvijou, A., Safari, H., & Ameri, H. (2020). Comparing the performance of the EQ-5D-5L with two versions of the SF-6Dv2 in patients with breast cancer. Health Services and Outcomes Research Methodology, 20(2), 183–194.CrossRef Nahvijou, A., Safari, H., & Ameri, H. (2020). Comparing the performance of the EQ-5D-5L with two versions of the SF-6Dv2 in patients with breast cancer. Health Services and Outcomes Research Methodology, 20(2), 183–194.CrossRef
13.
go back to reference Zare, F., Ameri, H., Madadizadeh, F., & Reza, A. M. (2020). Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus. SAGE Open Medicine, 8, 2050312120965314.CrossRefPubMedPubMedCentral Zare, F., Ameri, H., Madadizadeh, F., & Reza, A. M. (2020). Health-related quality of life and its associated factors in patients with type 2 diabetes mellitus. SAGE Open Medicine, 8, 2050312120965314.CrossRefPubMedPubMedCentral
14.
go back to reference Arab-Zozani, M., Safari, H., Dori, Z., Afshari, S., Ameri, H., Namiranian, N., et al. (2022). Estimating utility values for health states of DFU patients using EQ-5D-5L and cTTO. The International Journal of Lower Extremity Wounds., 21(1), 41–49.CrossRefPubMed Arab-Zozani, M., Safari, H., Dori, Z., Afshari, S., Ameri, H., Namiranian, N., et al. (2022). Estimating utility values for health states of DFU patients using EQ-5D-5L and cTTO. The International Journal of Lower Extremity Wounds., 21(1), 41–49.CrossRefPubMed
15.
go back to reference Ahadi, M. S., Vahidpour, N., Togha, M., Daroudi, R., Nadjafi-Semnani, F., Mohammadshirazi, Z., et al. (2021). Assessment of utility in migraine: Mapping the migraine-specific questionnaire to the EQ-5D-5L. Value in Health Regional Issues., 25, 57–63.CrossRefPubMed Ahadi, M. S., Vahidpour, N., Togha, M., Daroudi, R., Nadjafi-Semnani, F., Mohammadshirazi, Z., et al. (2021). Assessment of utility in migraine: Mapping the migraine-specific questionnaire to the EQ-5D-5L. Value in Health Regional Issues., 25, 57–63.CrossRefPubMed
16.
go back to reference Akbari Sari, A., Karimi, F., Emrani, Z., Zeraati, H., Olyaeemanesh, A., & Daroudi, R. (2021). The impact of common chronic conditions on health-related quality of life: A general population survey in Iran using EQ-5D-5L. Cost Effectiveness and Resource Allocation, 19(1), 1–7.CrossRef Akbari Sari, A., Karimi, F., Emrani, Z., Zeraati, H., Olyaeemanesh, A., & Daroudi, R. (2021). The impact of common chronic conditions on health-related quality of life: A general population survey in Iran using EQ-5D-5L. Cost Effectiveness and Resource Allocation, 19(1), 1–7.CrossRef
18.
go back to reference Ameri, H., Safari, H., Yousefi, M., Goudarzi, R., & Soofi, M. (2020). Interim value set for the EQ-5D-5L in Iran using the crosswalk method. Medical Journal of the Islamic Republic of Iran, 34, 121.PubMedPubMedCentral Ameri, H., Safari, H., Yousefi, M., Goudarzi, R., & Soofi, M. (2020). Interim value set for the EQ-5D-5L in Iran using the crosswalk method. Medical Journal of the Islamic Republic of Iran, 34, 121.PubMedPubMedCentral
19.
go back to reference Stolk, E., Ludwig, K., Rand, K., van Hout, B., & Ramos-Goñi, J. M. (2019). Overview, update, and lessons learned from the international EQ-5D-5L valuation work: Version 2 of the EQ-5D-5L valuation protocol. Value in Health, 22(1), 23–30.CrossRefPubMed Stolk, E., Ludwig, K., Rand, K., van Hout, B., & Ramos-Goñi, J. M. (2019). Overview, update, and lessons learned from the international EQ-5D-5L valuation work: Version 2 of the EQ-5D-5L valuation protocol. Value in Health, 22(1), 23–30.CrossRefPubMed
20.
go back to reference Oppe, M., Rand-Hendriksen, K., Shah, K., Ramos-Goñi, J. M., & Luo, N. (2016). EuroQol protocols for time trade-off valuation of health outcomes. PharmacoEconomics, 34(10), 993–1004.CrossRefPubMedPubMedCentral Oppe, M., Rand-Hendriksen, K., Shah, K., Ramos-Goñi, J. M., & Luo, N. (2016). EuroQol protocols for time trade-off valuation of health outcomes. PharmacoEconomics, 34(10), 993–1004.CrossRefPubMedPubMedCentral
21.
go back to reference Oppe, M., Devlin, N. J., van Hout, B., Krabbe, P. F., & de Charro, F. (2014). A program of methodological research to arrive at the new international EQ-5D-5L valuation protocol. Value in Health, 17(4), 445–453.CrossRefPubMed Oppe, M., Devlin, N. J., van Hout, B., Krabbe, P. F., & de Charro, F. (2014). A program of methodological research to arrive at the new international EQ-5D-5L valuation protocol. Value in Health, 17(4), 445–453.CrossRefPubMed
22.
go back to reference Ramos-Goñi, J. M., Oppe, M., Slaap, B., Busschbach, J. J., & Stolk, E. (2017). Quality control process for EQ-5D-5L valuation studies. Value in Health, 20(3), 466–473.CrossRefPubMed Ramos-Goñi, J. M., Oppe, M., Slaap, B., Busschbach, J. J., & Stolk, E. (2017). Quality control process for EQ-5D-5L valuation studies. Value in Health, 20(3), 466–473.CrossRefPubMed
24.
go back to reference Ramos-Goñi, J. M., Pinto-Prades, J. L., Oppe, M., Cabasés, J. M., Serrano-Aguilar, P., & Rivero-Arias, O. (2017). Valuation and modeling of EQ-5D-5L health states using a hybrid approach. Medical Care, 55(7), e51–e58.CrossRefPubMed Ramos-Goñi, J. M., Pinto-Prades, J. L., Oppe, M., Cabasés, J. M., Serrano-Aguilar, P., & Rivero-Arias, O. (2017). Valuation and modeling of EQ-5D-5L health states using a hybrid approach. Medical Care, 55(7), e51–e58.CrossRefPubMed
25.
go back to reference Welie, A. G., Gebretekle, G. B., Stolk, E., Mukuria, C., Krahn, M. D., Enquoselassie, F., et al. (2020). Valuing health state: An EQ-5D-5L value set for Ethiopians. Value in Health Regional Issues, 22, 7–14.CrossRefPubMed Welie, A. G., Gebretekle, G. B., Stolk, E., Mukuria, C., Krahn, M. D., Enquoselassie, F., et al. (2020). Valuing health state: An EQ-5D-5L value set for Ethiopians. Value in Health Regional Issues, 22, 7–14.CrossRefPubMed
26.
go back to reference Al Shabasy, S., Abbassi, M., Finch, A., Roudijk, B., Baines, D., & Farid, S. (2022). The EQ-5D-5L valuation study in Egypt. PharmacoEconomics, 40(4), 433–447.CrossRefPubMed Al Shabasy, S., Abbassi, M., Finch, A., Roudijk, B., Baines, D., & Farid, S. (2022). The EQ-5D-5L valuation study in Egypt. PharmacoEconomics, 40(4), 433–447.CrossRefPubMed
27.
go back to reference Purba, F. D., Hunfeld, J. A., Iskandarsyah, A., Fitriana, T. S., Sadarjoen, S. S., Ramos-Goñi, J. M., et al. (2017). The Indonesian EQ-5D-5L value set. PharmacoEconomics, 35(11), 1153–1165.CrossRefPubMedPubMedCentral Purba, F. D., Hunfeld, J. A., Iskandarsyah, A., Fitriana, T. S., Sadarjoen, S. S., Ramos-Goñi, J. M., et al. (2017). The Indonesian EQ-5D-5L value set. PharmacoEconomics, 35(11), 1153–1165.CrossRefPubMedPubMedCentral
28.
go back to reference Versteegh, M. M., Vermeulen, K. M., Evers, S. M., De Wit, G. A., Prenger, R., & Stolk, E. A. (2016). Dutch tariff for the five-level version of EQ-5D. Value in Health, 19(4), 343–352.CrossRef Versteegh, M. M., Vermeulen, K. M., Evers, S. M., De Wit, G. A., Prenger, R., & Stolk, E. A. (2016). Dutch tariff for the five-level version of EQ-5D. Value in Health, 19(4), 343–352.CrossRef
29.
go back to reference Luo, N., Liu, G., Li, M., Guan, H., Jin, X., & Rand-Hendriksen, K. (2017). Estimating an EQ-5D-5L value set for China. Value in Health, 20(4), 662–669.CrossRefPubMed Luo, N., Liu, G., Li, M., Guan, H., Jin, X., & Rand-Hendriksen, K. (2017). Estimating an EQ-5D-5L value set for China. Value in Health, 20(4), 662–669.CrossRefPubMed
30.
go back to reference Pattanaphesaj, J., Thavorncharoensap, M., Ramos-Goñi, J. M., Tongsiri, S., Ingsrisawang, L., & Teerawattananon, Y. (2018). The EQ-5D-5L valuation study in Thailand. Expert Review of Pharmacoeconomics & Outcomes Research, 18(5), 551–558.CrossRef Pattanaphesaj, J., Thavorncharoensap, M., Ramos-Goñi, J. M., Tongsiri, S., Ingsrisawang, L., & Teerawattananon, Y. (2018). The EQ-5D-5L valuation study in Thailand. Expert Review of Pharmacoeconomics & Outcomes Research, 18(5), 551–558.CrossRef
31.
32.
go back to reference Mai, V. Q., Sun, S., Minh, H. V., Luo, N., Giang, K. B., Lindholm, L., et al. (2020). An EQ-5D-5L value set for Vietnam. Quality of Life Research, 29(7), 1923–1933.CrossRefPubMedPubMedCentral Mai, V. Q., Sun, S., Minh, H. V., Luo, N., Giang, K. B., Lindholm, L., et al. (2020). An EQ-5D-5L value set for Vietnam. Quality of Life Research, 29(7), 1923–1933.CrossRefPubMedPubMedCentral
33.
go back to reference Gildner, T. E., Snodgrass, J. J., Evans, C., & Kowal, P. (2019). Associations between physical function and subjective well-being in older adults from low-and middle-income countries: Results from the study on global ageing and adult health (SAGE). Journal of Aging and Physical Activity, 27(2), 213–221.CrossRefPubMed Gildner, T. E., Snodgrass, J. J., Evans, C., & Kowal, P. (2019). Associations between physical function and subjective well-being in older adults from low-and middle-income countries: Results from the study on global ageing and adult health (SAGE). Journal of Aging and Physical Activity, 27(2), 213–221.CrossRefPubMed
34.
go back to reference Shiroiwa, T., Ikeda, S., Noto, S., Igarashi, A., Fukuda, T., Saito, S., et al. (2016). Comparison of value set based on DCE and/or TTO data: Scoring for EQ-5D-5L health states in Japan. Value in Health, 19(5), 648–654.CrossRefPubMed Shiroiwa, T., Ikeda, S., Noto, S., Igarashi, A., Fukuda, T., Saito, S., et al. (2016). Comparison of value set based on DCE and/or TTO data: Scoring for EQ-5D-5L health states in Japan. Value in Health, 19(5), 648–654.CrossRefPubMed
35.
go back to reference Xie, F., Pullenayegum, E., Gaebel, K., Bansback, N., Bryan, S., Ohinmaa, A., et al. (2016). A time trade-off-derived value set of the EQ-5D-5L for Canada. Medical Care, 54(1), 98.CrossRefPubMed Xie, F., Pullenayegum, E., Gaebel, K., Bansback, N., Bryan, S., Ohinmaa, A., et al. (2016). A time trade-off-derived value set of the EQ-5D-5L for Canada. Medical Care, 54(1), 98.CrossRefPubMed
36.
go back to reference Jensen, C. E., Sørensen, S. S., Gudex, C., Jensen, M. B., Pedersen, K. M., & Ehlers, L. H. (2021). The Danish EQ-5D-5L value set: A hybrid model using cTTO and DCE data. Applied Health Economics and Health Policy, 19(4), 579–591.CrossRefPubMedPubMedCentral Jensen, C. E., Sørensen, S. S., Gudex, C., Jensen, M. B., Pedersen, K. M., & Ehlers, L. H. (2021). The Danish EQ-5D-5L value set: A hybrid model using cTTO and DCE data. Applied Health Economics and Health Policy, 19(4), 579–591.CrossRefPubMedPubMedCentral
37.
go back to reference Tsuchiya, A., Ikeda, S., Ikegami, N., Nishimura, S., Sakai, I., Fukuda, T., et al. (2002). Estimating an EQ-5D population value set: The case of Japan. Health Economics, 11(4), 341–353.CrossRefPubMed Tsuchiya, A., Ikeda, S., Ikegami, N., Nishimura, S., Sakai, I., Fukuda, T., et al. (2002). Estimating an EQ-5D population value set: The case of Japan. Health Economics, 11(4), 341–353.CrossRefPubMed
Metagegevens
Titel
A national survey of Iranian general population to estimate a value set for the EQ-5D-5L
Auteurs
Somayeh Afshari
Rajabali Daroudi
Reza Goudarzi
Alireza Mahboub–Ahari
Mehdi Yaseri
Ali Akbari Sari
Hosein Ameri
Sajjad Bahariniya
Alireza Oliaei-Manesh
Khalil Kalavani
Zahra Zare
Elham Hasannezhad
Mohammadamin Mirzaei
Zahra Amiri
Publicatiedatum
10-03-2023
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 7/2023
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-023-03378-1