Skip to main content
Top

2006 | OriginalPaper | Hoofdstuk

5 Medicatietrouw

Auteurs : Dr. J. Dobber, dr. H. Boter, dr. B. van Meijel

Gepubliceerd in: Zorg rondom schizofrenie

Uitgeverij: Bohn Stafleu van Loghum

share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Samenvatting

Bij mensen met schizofrenie vormt medicatie een belangrijke pijler in de behandeling. De behandeling met antipsychotica is onder meer gericht op het bestrijden van de symptomen en de preventie van een psychotische terugval. Ondanks de bewezen effectiviteit van de medicatie blijkt 16 tot 50 procent van de patiënten binnen een jaar en 54 tot 81 procent binnen twee jaar een terugval te krijgen. (1,2) Een dergelijke gebeurtenis heeft grote nadelige gevolgen voor het welzijn van de patiënt en voor de mensen in zijn omgeving. Ook leidt het tot extra kosten in de zorg door inzet van meer mensen en middelen.
Voetnoten
1
Medicatietrouw verwijst niet naar het gedrag van de patiënt als een passieve ontvanger van de zorg die moet gehoorzamen, maar benadrukt de actieve rol van de patiënt in het besluitvormingsproces. Medicatieontrouw is dan ook niet het probleem van de patiënt of de behandelaar maar een uiting van een discrepantie tussen de doelen van de patiënt en die van de behandelaar.
 
2
‘Home Visit’ en ‘Clinical Visit’ zijn interventies waarbij het huisbezoek en het polibezoek op een specifieke manier worden ingevuld. Omdat vertaling met ‘huisbezoek’ en ‘polibezoek’ verwarring met gewone huisbezoeken en polibezoeken zou kunnen opleveren, wordt hier gekozen specifieke interventies uit de Engelstalige literatuur onvertaald te laten.
 
Literatuur
1.
go back to reference Robinson, D., Woerner, M.G., Alvir, J.M., Bilder, R., Goldman, R., Geisler, S., Koreen, A., Sheitman, B., Chakos, M., Mayerhoff, D. & Lieberman, J.A. (1999). Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Archives of General Psychiatry 56, 241–247.PubMedCrossRef Robinson, D., Woerner, M.G., Alvir, J.M., Bilder, R., Goldman, R., Geisler, S., Koreen, A., Sheitman, B., Chakos, M., Mayerhoff, D. & Lieberman, J.A. (1999). Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Archives of General Psychiatry 56, 241–247.PubMedCrossRef
2.
go back to reference Weiden, P.J. & Olfson, M. (1995). Cost of relapse in schizophrenia. Schizophrenia Bulletin 21, 419–429.PubMedCrossRef Weiden, P.J. & Olfson, M. (1995). Cost of relapse in schizophrenia. Schizophrenia Bulletin 21, 419–429.PubMedCrossRef
3.
go back to reference Green, J.H. (1998). Frequent rehospitalization and noncompliance with treatment. Hospital & Community Psychiatry 39, 963–966. Green, J.H. (1998). Frequent rehospitalization and noncompliance with treatment. Hospital & Community Psychiatry 39, 963–966.
4.
go back to reference Ayuso-Gutierrez, J.L. & Rio Vega, J.M. (1997). Factors influencing relapse in the longterm course of schizophrenia. Schizophrenia Research 28, 199–206.PubMedCrossRef Ayuso-Gutierrez, J.L. & Rio Vega, J.M. (1997). Factors influencing relapse in the longterm course of schizophrenia. Schizophrenia Research 28, 199–206.PubMedCrossRef
5.
go back to reference Dolder, C.R., Lacro, J.P., Dunn, L.B. & Jeste, D.V. (2002). Antipsychotic medication adherence: is there a difference between typical and atypical agents? American Journal of Psychiatry 159, 103–108.PubMedCrossRef Dolder, C.R., Lacro, J.P., Dunn, L.B. & Jeste, D.V. (2002). Antipsychotic medication adherence: is there a difference between typical and atypical agents? American Journal of Psychiatry 159, 103–108.PubMedCrossRef
6.
go back to reference Novak-Grubic, V. & Tavcar, R. (2002). Predictors of noncompliance in males with firstepisode schizophrenia, schizophreniform and schizoaffective disorder. European Psychiatry 17, 148–154.PubMedCrossRef Novak-Grubic, V. & Tavcar, R. (2002). Predictors of noncompliance in males with firstepisode schizophrenia, schizophreniform and schizoaffective disorder. European Psychiatry 17, 148–154.PubMedCrossRef
7.
go back to reference Robinson, D.G., Woerner, M.G., Alvir, J.M., Bilder, R.M., Hinrichsen, G.A. & Lieberman, J.A. (2002). Predictors of medication discontinuation by patients with first-episode schizophrenia and schizoaffective disorder. Schizophrenia Research 57, 209–219.PubMedCrossRef Robinson, D.G., Woerner, M.G., Alvir, J.M., Bilder, R.M., Hinrichsen, G.A. & Lieberman, J.A. (2002). Predictors of medication discontinuation by patients with first-episode schizophrenia and schizoaffective disorder. Schizophrenia Research 57, 209–219.PubMedCrossRef
8.
go back to reference Verdoux, H., Lengronne, J., Liraud, F., Gonzales, B., Assens, F., Abalan, F. & Os, J. van (2000).Medication adherence in psychosis: predictors and impact on outcome.A 2-year follow-up of first-admitted subjects. Acta Psychiatrica Scandinavica 102, 203–210.PubMedCrossRef Verdoux, H., Lengronne, J., Liraud, F., Gonzales, B., Assens, F., Abalan, F. & Os, J. van (2000).Medication adherence in psychosis: predictors and impact on outcome.A 2-year follow-up of first-admitted subjects. Acta Psychiatrica Scandinavica 102, 203–210.PubMedCrossRef
9.
go back to reference Weiden, P., Rapkin, B., Mott, T., Zygmunt, A., Goldman, D., Horvitz-Lennon, M. & Frances, A. (1994). Rating of Medication Influences (ROMI) scale in schizophrenia. Schizophrenia Bulletin 20, 297–310.PubMedCrossRef Weiden, P., Rapkin, B., Mott, T., Zygmunt, A., Goldman, D., Horvitz-Lennon, M. & Frances, A. (1994). Rating of Medication Influences (ROMI) scale in schizophrenia. Schizophrenia Bulletin 20, 297–310.PubMedCrossRef
10.
go back to reference Gilmer, T.P., Dolder, C.R., Lacro, J.P., Folsom, D.P., Lindamer, L., Garcia, P. & Jeste, D.V. (2004). Adherence to treatment with antipsychoticmedication and health care costs amongmedicaid beneficiaries with schizophrenia. American Journal of Psychiatry 161, 692–699.PubMedCrossRef Gilmer, T.P., Dolder, C.R., Lacro, J.P., Folsom, D.P., Lindamer, L., Garcia, P. & Jeste, D.V. (2004). Adherence to treatment with antipsychoticmedication and health care costs amongmedicaid beneficiaries with schizophrenia. American Journal of Psychiatry 161, 692–699.PubMedCrossRef
11.
go back to reference Dobber, J., Meijel, B. van & Winter, C.P. de (2004).Medicatie-compliance bij mensen met schizofrenie. Een literatuurstudie naar de bijdrage van verpleegkundigen. Verpleegkunde 19(4), 183–299. Dobber, J., Meijel, B. van & Winter, C.P. de (2004).Medicatie-compliance bij mensen met schizofrenie. Een literatuurstudie naar de bijdrage van verpleegkundigen. Verpleegkunde 19(4), 183–299.
12.
go back to reference Fenton, W.S., Blyler, C.R. & Heinssen, R.K. (1997).Determinants of medication compliance in schizophrenia: emperical and clinical findings. Schizophrenia Bulletin 23, 637–651.PubMedCrossRef Fenton, W.S., Blyler, C.R. & Heinssen, R.K. (1997).Determinants of medication compliance in schizophrenia: emperical and clinical findings. Schizophrenia Bulletin 23, 637–651.PubMedCrossRef
13.
go back to reference Bunn, M.H., O’Connor, A.M., Tansey, M.S., Jones, B.D.W. & Stinson, L.E. (1997). Characteristics of clients with schizophrenia who express certainty or uncertainty about continuing treatment with cepot neuroleptic medication. Archives of Psychiatric Nursing 11, 238–248.PubMedCrossRef Bunn, M.H., O’Connor, A.M., Tansey, M.S., Jones, B.D.W. & Stinson, L.E. (1997). Characteristics of clients with schizophrenia who express certainty or uncertainty about continuing treatment with cepot neuroleptic medication. Archives of Psychiatric Nursing 11, 238–248.PubMedCrossRef
14.
go back to reference Gray, R., Wykes, T. & Gournay, K. (2002). From compliance to concordance: a review of the literature on interventions to enhance compliance with antipsychotic medication. Journal of Psychiatric and Mental Health Nursing 9, 277–284.PubMedCrossRef Gray, R., Wykes, T. & Gournay, K. (2002). From compliance to concordance: a review of the literature on interventions to enhance compliance with antipsychotic medication. Journal of Psychiatric and Mental Health Nursing 9, 277–284.PubMedCrossRef
15.
go back to reference Munich, R.L. (1997). Contemporary treatment of schizophrenia. Bulletin of the Menninger Clinic 61, 189–221.PubMed Munich, R.L. (1997). Contemporary treatment of schizophrenia. Bulletin of the Menninger Clinic 61, 189–221.PubMed
16.
go back to reference Olfson, M., Mechanic, D., Hansell, S., Boyer, C.A., Walkup, J. & Weiden, P.J. (2000). Predicting medication noncompliance after hospital discharge among patients with schizophrenia. Psychiatric Services 51, 216–222.PubMedCrossRef Olfson, M., Mechanic, D., Hansell, S., Boyer, C.A., Walkup, J. & Weiden, P.J. (2000). Predicting medication noncompliance after hospital discharge among patients with schizophrenia. Psychiatric Services 51, 216–222.PubMedCrossRef
17.
go back to reference Fleischhacker, W.W., Oehl, M.A. & Hummer, M. (2003). Factors influencing compliance in schizophrenia patients. Journal of Clinical Psychiatry 64(suppl 16), 10–13.PubMedCrossRef Fleischhacker, W.W., Oehl, M.A. & Hummer, M. (2003). Factors influencing compliance in schizophrenia patients. Journal of Clinical Psychiatry 64(suppl 16), 10–13.PubMedCrossRef
18.
go back to reference Larco, J.P., Dunn, L.B., Dolder, C.R., Leckband, S.G. & Jeste, D.V. (2002). Prevalence of and risk factors for medication nonadherence in patients with schizophrenia: A comprehensive review of recent literature. Journal of Clinical Psychiatry 63, 892–909.CrossRef Larco, J.P., Dunn, L.B., Dolder, C.R., Leckband, S.G. & Jeste, D.V. (2002). Prevalence of and risk factors for medication nonadherence in patients with schizophrenia: A comprehensive review of recent literature. Journal of Clinical Psychiatry 63, 892–909.CrossRef
19.
go back to reference APA(2004). Practice guideline for the treatment of patients with schizophrenia. Arlington: American Psychiatric Association. APA(2004). Practice guideline for the treatment of patients with schizophrenia. Arlington: American Psychiatric Association.
20.
go back to reference Pool, A. (1999). Autonomie en autoriteit in de verpleegkundige zorg, In: A. Pool, J. Lambregts (red.), Verpleegkundige zorgverlening aan chronisch zieken (p. 237–252).Utrecht: Lemma. Pool, A. (1999). Autonomie en autoriteit in de verpleegkundige zorg, In: A. Pool, J. Lambregts (red.), Verpleegkundige zorgverlening aan chronisch zieken (p. 237–252).Utrecht: Lemma.
21.
go back to reference Thompson, K., Kulkarni, J. & Sergejew, A.A. (2000). Reliability and validity of a new Medication Adherence Raring Scale (MARS) for psychoses. Schizophrenia Research 42, 241–247.PubMedCrossRef Thompson, K., Kulkarni, J. & Sergejew, A.A. (2000). Reliability and validity of a new Medication Adherence Raring Scale (MARS) for psychoses. Schizophrenia Research 42, 241–247.PubMedCrossRef
22.
go back to reference Marder, S.R. (1998). Facilitating compliance with antipsychotic medication. Journal of Clinical Psychiatry 59(suppl 3), 21–25.PubMed Marder, S.R. (1998). Facilitating compliance with antipsychotic medication. Journal of Clinical Psychiatry 59(suppl 3), 21–25.PubMed
23.
go back to reference Miller, W.R. & Rollnick, S. (2002). Motivational interviewing: preparing people for change. 2nd ed. New York/London: The Guilford Press. Miller, W.R. & Rollnick, S. (2002). Motivational interviewing: preparing people for change. 2nd ed. New York/London: The Guilford Press.
24.
go back to reference Lysacker, P.H., Bell, M.D., Bryson, G.J. & Kaplan, E. (1998). Insight and interperson function in schizophrenia. The Journal of Nervous and Mental Disease 186, 432–436.CrossRef Lysacker, P.H., Bell, M.D., Bryson, G.J. & Kaplan, E. (1998). Insight and interperson function in schizophrenia. The Journal of Nervous and Mental Disease 186, 432–436.CrossRef
25.
go back to reference Birchwood, M., Smith, J., Drury, V., Healy, J., Macmillan, F. & Slade, M. (1994).A selfreport insight scale for psychosis: reliability, validity and sensitivity to change. Acta Psychiatrica Scandinavica 89, 62–67.PubMedCrossRef Birchwood, M., Smith, J., Drury, V., Healy, J., Macmillan, F. & Slade, M. (1994).A selfreport insight scale for psychosis: reliability, validity and sensitivity to change. Acta Psychiatrica Scandinavica 89, 62–67.PubMedCrossRef
26.
go back to reference George, R.D. & Howell, C.C. (1996). Clients with schizophrenia and their caregivers perceptions of frequent psychiatric rehospitalisations. Issues in Mental Health Nursing 17, 573–588.PubMedCrossRef George, R.D. & Howell, C.C. (1996). Clients with schizophrenia and their caregivers perceptions of frequent psychiatric rehospitalisations. Issues in Mental Health Nursing 17, 573–588.PubMedCrossRef
27.
go back to reference Smith, T.E., Hull, J.W., Goodman, M., Hedayat-Harris, A., Willson, D.F., Israel, L.M. & Munich, R.L. (1999). The relative influences of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder. The Journal of Nervous and Mental Disease 187, 102–108.PubMedCrossRef Smith, T.E., Hull, J.W., Goodman, M., Hedayat-Harris, A., Willson, D.F., Israel, L.M. & Munich, R.L. (1999). The relative influences of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder. The Journal of Nervous and Mental Disease 187, 102–108.PubMedCrossRef
28.
go back to reference Bosch, R.J. van den (2000). Schizofrenie en andere psychotische stoornissen. In:W. Vandereyken, C.A.L.Hoogduin & P.M.G. Emmelkamp (red), Handboek psychopathologie deel 1. 3de druk. Houten: Bohn Stafleu van Loghum. Bosch, R.J. van den (2000). Schizofrenie en andere psychotische stoornissen. In:W. Vandereyken, C.A.L.Hoogduin & P.M.G. Emmelkamp (red), Handboek psychopathologie deel 1. 3de druk. Houten: Bohn Stafleu van Loghum.
29.
go back to reference Frank, A.F. & Gunderson, J.G. (1990). The role of the therapeutic alliance in the treatment of schizophrenia: relationship to course and outcome. Archives Gen. Psychiatry 47, 228–236.CrossRef Frank, A.F. & Gunderson, J.G. (1990). The role of the therapeutic alliance in the treatment of schizophrenia: relationship to course and outcome. Archives Gen. Psychiatry 47, 228–236.CrossRef
30.
go back to reference Marland, G.R. (1999).Atypical neuroleptics: autonomy and compliance? Journal of Advanced Nursing 29, 615–622.PubMedCrossRef Marland, G.R. (1999).Atypical neuroleptics: autonomy and compliance? Journal of Advanced Nursing 29, 615–622.PubMedCrossRef
31.
go back to reference Hogan, T.P., Awad, A.G. & Eastwood, R. (1983).A self-report scale predictive of drug compliance in schizophrenics: reliability and discriminative validity. Psychol.Med. 13, 177–183.PubMedCrossRef Hogan, T.P., Awad, A.G. & Eastwood, R. (1983).A self-report scale predictive of drug compliance in schizophrenics: reliability and discriminative validity. Psychol.Med. 13, 177–183.PubMedCrossRef
33.
go back to reference Naber, D. (1995). A self-rating to measure subjective effects of neuroleptic drugs, relationships to objective psychopathology, quality of life, compliance and other clinical variables. Int. Clin. Psychopharmacol. 10, 133–138.PubMed Naber, D. (1995). A self-rating to measure subjective effects of neuroleptic drugs, relationships to objective psychopathology, quality of life, compliance and other clinical variables. Int. Clin. Psychopharmacol. 10, 133–138.PubMed
34.
go back to reference Haan, L. de, Weisfelt, M., Dingemans, P.M.A.J., Linszen, D.H. & Wouters, L. (2002). Psychometric properties of the SubjectiveWell-Being Under Neuroleptics scale and the Subjective Deficit Syndrome Scale. Psychopharmacology 162, 24–28.PubMedCrossRef Haan, L. de, Weisfelt, M., Dingemans, P.M.A.J., Linszen, D.H. & Wouters, L. (2002). Psychometric properties of the SubjectiveWell-Being Under Neuroleptics scale and the Subjective Deficit Syndrome Scale. Psychopharmacology 162, 24–28.PubMedCrossRef
35.
go back to reference Dobber, J., Meijel, B. van & Winter, C.P. de (2002). Schatting van Draagvlak Medicatie bij Schizofrenie (SDMS). Bijlage bij doctoraalscriptie gezondheidswetenschappen, verplegingswetenschap.Maastricht/Utrecht. Dobber, J., Meijel, B. van & Winter, C.P. de (2002). Schatting van Draagvlak Medicatie bij Schizofrenie (SDMS). Bijlage bij doctoraalscriptie gezondheidswetenschappen, verplegingswetenschap.Maastricht/Utrecht.
36.
go back to reference Marland, G.R. & Sharkey, V. (1999).Depot neuroleptics, schizophrenia and the role of the nurse: is practice evidence based? A review of the literature. Journal of Advanced Nursing 30, 1255–1262.PubMedCrossRef Marland, G.R. & Sharkey, V. (1999).Depot neuroleptics, schizophrenia and the role of the nurse: is practice evidence based? A review of the literature. Journal of Advanced Nursing 30, 1255–1262.PubMedCrossRef
38.
go back to reference Pekkela, E., & Merrinder, L. (2003). Psychoeducation for schizophrenia (Cochrane Review). In: The Cochrane Library, Issue 4, Chichester, UK: JohnWiley & Sons, Ltd. Pekkela, E., & Merrinder, L. (2003). Psychoeducation for schizophrenia (Cochrane Review). In: The Cochrane Library, Issue 4, Chichester, UK: JohnWiley & Sons, Ltd.
39.
go back to reference Herz, M.I. (1996). Psychosocial treatment. Psychiatric Annals 26, 531–535.CrossRef Herz, M.I. (1996). Psychosocial treatment. Psychiatric Annals 26, 531–535.CrossRef
40.
go back to reference Bauml, J., Kissling, W. & Pitschel-Walz, G. (1996). Psychoedukative Gruppen für Scizophrene Patienten: Einfluss aufWissensstand und Compliance. Nervenheilkunde 15, 145–150. Bauml, J., Kissling, W. & Pitschel-Walz, G. (1996). Psychoedukative Gruppen für Scizophrene Patienten: Einfluss aufWissensstand und Compliance. Nervenheilkunde 15, 145–150.
41.
go back to reference Macpherson, R., Jerrom, B. & Hughes, A. (1996).A controlled study of education about drug treatment in schizophrenia. British Journal of Psychiatry 168, 709–717.PubMedCrossRef Macpherson, R., Jerrom, B. & Hughes, A. (1996).A controlled study of education about drug treatment in schizophrenia. British Journal of Psychiatry 168, 709–717.PubMedCrossRef
42.
go back to reference Kemp, R., David, A. & Hayward, P. (1996). Compliance therapy: An intervention targeting insight and treatment adherence in psychotic patients. Behavioural and Cognitive Psychotherapy 24, 331–350.CrossRef Kemp, R., David, A. & Hayward, P. (1996). Compliance therapy: An intervention targeting insight and treatment adherence in psychotic patients. Behavioural and Cognitive Psychotherapy 24, 331–350.CrossRef
43.
go back to reference Liberman, R.P. (1996). Trainingsmodule Omgaan met antipsychotische medicatie. Vaardigheidstraining voor een zelfstandig leven. Leuven/Apeldoorn: Garant. Liberman, R.P. (1996). Trainingsmodule Omgaan met antipsychotische medicatie. Vaardigheidstraining voor een zelfstandig leven. Leuven/Apeldoorn: Garant.
44.
go back to reference Arends, J., Vleugel, B. van der & Meijel, B. van (2000).De Liberman-modules: een beschrijving van de mogelijkheden van zelfmanagement. In: G. Pieters & M. van der Gaag (red.), Rehablitatiestrategieën bij schizofrenie en langdurig zorgafhankelijke patiënten. Houten/Diegem: Bohn Stafleu van Loghum. Arends, J., Vleugel, B. van der & Meijel, B. van (2000).De Liberman-modules: een beschrijving van de mogelijkheden van zelfmanagement. In: G. Pieters & M. van der Gaag (red.), Rehablitatiestrategieën bij schizofrenie en langdurig zorgafhankelijke patiënten. Houten/Diegem: Bohn Stafleu van Loghum.
45.
go back to reference Kelly, G.R. & Scott, J.E. (1990).Medication compliance and health education among outpatients with chronic mental disorders. Medical Care 28, 1181–1197.PubMedCrossRef Kelly, G.R. & Scott, J.E. (1990).Medication compliance and health education among outpatients with chronic mental disorders. Medical Care 28, 1181–1197.PubMedCrossRef
46.
go back to reference Landelijke Stuurgroep Multidiscplinaire Richtlijnontwikkeling in de GGZ (2005). Multidisciplinaire richtlijn Schizofrenie. Utrecht: Trimbos-instituut. Landelijke Stuurgroep Multidiscplinaire Richtlijnontwikkeling in de GGZ (2005). Multidisciplinaire richtlijn Schizofrenie. Utrecht: Trimbos-instituut.
47.
go back to reference Corrigan, P.W., Liberman, R.P. & Engel, J.D. (1990). From noncompliance to collaboration in the treatment of schizophrenia. Hospital and Community Psychiatry 41, 1203–1211.PubMed Corrigan, P.W., Liberman, R.P. & Engel, J.D. (1990). From noncompliance to collaboration in the treatment of schizophrenia. Hospital and Community Psychiatry 41, 1203–1211.PubMed
48.
go back to reference Gaebel, W., Jänner, M., Frommann, N., Pietzcker, A., Köpcke, W., Linden, M., Müller-Spahn, F. & Tegeler, J. (2002). First vs multiple episode schizophrenia: two-year outcome of intermittent and maintenance medication strategies. Schizophrenia Research 53, 145–159.PubMedCrossRef Gaebel, W., Jänner, M., Frommann, N., Pietzcker, A., Köpcke, W., Linden, M., Müller-Spahn, F. & Tegeler, J. (2002). First vs multiple episode schizophrenia: two-year outcome of intermittent and maintenance medication strategies. Schizophrenia Research 53, 145–159.PubMedCrossRef
49.
go back to reference Carpenter, W.T. (1996).Maintenance therapy of persons with schizophrenia. Journal of Clinical Psychiatry 57(suppl 9), 10–18.PubMed Carpenter, W.T. (1996).Maintenance therapy of persons with schizophrenia. Journal of Clinical Psychiatry 57(suppl 9), 10–18.PubMed
Metagegevens
Titel
5 Medicatietrouw
Auteurs
Dr. J. Dobber
dr. H. Boter
dr. B. van Meijel
Copyright
2006
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-313-9522-4_5