Gepubliceerd in:

01-02-2013

The predictive value of FiO2 for outcome of children with respiratory syncytial virus-induced acute respiratory distress syndrome

Auteurs: K.M. Schene, E. van den Berg, R.M. Wösten-van Asperen, R.R. van Rijn, A.P. Bos, J.B.M. van Woensel

Gepubliceerd in: Tijdschrift voor Kindergeneeskunde | bijlage 1/2013

Extract

Respiratory syncytial virus (RSV) infection can progress to acute respiratory distress syndrome (ARDS) in infants. ARDS is a life threatening condition that is characterized by severe hypoxemia defined as PaO2/FiO2 ratio < 300 mmHg. Many trials use this ratio as an inclusion criterion. Recently, however, it has been shown in adults with ARDS that FiO2, independently predicts mortality, suggesting that the PaO2/FiO2 ratio alone might be insufficient to identify patients for clinical trials. In this study we determined if FiO2 predicted the duration of mechanical ventilation (MV) and length of stay (LOS) in the pediatric intensive care unit (PICU) in infants with RSV-induced ARDS. …

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