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08-02-2017 | Uitgave 6/2017

Quality of Life Research 6/2017

Quality of life and uncertainty in Crohn’s disease

Quality of Life Research > Uitgave 6/2017
Galia Niv, Simona Bar Josef, Ofer Ben Bassat, Irit Avni, Lev Lictenstein, Yaron Niv, Sivia Barnoy



Crohn’s disease impairs patients’ perception of health and has a negative impact on health-related quality of life. Although it is apparent that uncertainty is a significant factor that decreases quality of life, it has never been studied in patients with Crohn’s disease. The objective of the present study was to examine the association between level of certainty, self-epistemic authority, Internet information gathering habits, and health-related quality of life.


A cross-sectional study of 105 Crohn’s disease patients was conducted. Data were collected using a questionnaire composed of five parts: (1) demographic and clinical information; (2) health-related quality of life; (3) level of certainty; (4) self-epistemic authority; and (5) Internet information gathering habits regarding Crohn’s disease.


A significant positive correlation was demonstrated between levels of certainty and health-related quality of life. Self-epistemic authority correlated positively with certainty, while information gathering via the Internet was related to decreased certainty. Multiple regression analysis for factors associated with health-related quality of life showed a positive association with the level of certainty, while negative associations were found between Internet information seeking and disease activity with the quality of life.


Level of certainty proved an important variable associated with health-related quality of life in Crohn’s disease patients. Improving patients’ self-epistemic authority can increase certainty and, thus, improve health-related quality of life.

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