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24-01-2022

Quality of life after stroke: a longitudinal analysis of a cluster randomized trial

Auteurs: Zhomart Orman, Amanda G. Thrift, Muideen T. Olaiya, David Ung, Dominique A. Cadilhac, Thanh Phan, Mark R. Nelson, Velandai K. Srikanth, Jason Vuong, Christopher F. Bladin, Richard P. Gerraty, Sharyn M. Fitzgerald, Judith Frayne, Joosup Kim, the STANDFIRM (Shared Team Approach between Nurses and Doctors For Improved Risk factor Management) Investigators

Gepubliceerd in: Quality of Life Research | Uitgave 8/2022

Abstract

Purpose

Health-related quality of life (QoL) is poor after stroke, but may be improved with comprehensive care plans. We aimed to determine the effects of an individualized management program on QoL in people with stroke or transient ischemic attack (TIA), describe changes in QoL over time, and identify variables associated with QoL.

Methods

This was a multicenter, cluster randomized controlled trial with blinded assessment of outcomes and intention‐to‐treat analysis. Patients with stroke or TIA aged ≥ 18 years were randomized by general practice to receive usual care or an intervention comprising a tailored chronic disease management plan and education. QoL was assessed at baseline and 3, 12, and 24 months after baseline using the Assessment of Quality of Life instrument. Patient responses were converted to utility scores ranging from − 0.04 (worse than death) to 1.00 (good health). Mixed-effects models were used for analyses.

Results

Among 563 participants recruited (mean age 68.4 years, 64.5% male), median utility scores ranged from 0.700 to 0.772 at different time points, with no difference observed between intervention and usual care groups. QoL improved significantly from baseline to 3 months (ß = 0.019; P = 0.015) and 12 months (ß = 0.033; P < 0.001), but not from baseline to 24 months (ß = 0.013; P = 0.140) in both groups combined. Older age, females, lower educational attainment, greater handicap, anxiety and depression were longitudinally associated with poor QoL.

Conclusion

An individualized management program did not improve QoL over 24 months. Those who are older, female, with lower educational attainment, greater anxiety, depression and handicap may require greater support.

Clinical trial registration

https://www.anzctr.org.au. Unique identifier: ACTRN12608000166370.

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Alleen toegankelijk voor geautoriseerde gebruikers

Lawrence, L., & Christie, D. (1979). Quality of life after stroke: A three-year follow-up. Age and Ageing, 8(3), 167–172. https://doi.org/10.1093/ageing/8.3.167CrossRefPubMed

Allen, K. R., Hazelett, S., Jarjoura, D., Wickstrom, G. C., Hua, K., Weinhardt, J., & Wright, K. (2002). Effectiveness of a postdischarge care management model for stroke and transient ischemic attack: A randomized trial. Journal of Stroke and Cerebrovascular Diseases, 11(2), 88–98. https://doi.org/10.1053/jscd.2002.127106CrossRefPubMed

Fryer, C. E., Luker, J. A., McDonnell, M. N., & Hillier, S. L. (2016). Self-management programs for quality of life in people with stroke. Stroke, 47(12), e266–e267. https://doi.org/10.1161/STROKEAHA.116.015253CrossRefPubMed

Harwood, M., Weatherall, M., Talemaitoga, A., Barber, P. A., Gommans, J., Taylor, W., McPherson, K., & McNaughton, H. (2012). Taking charge after stroke: Promoting self-directed rehabilitation to improve quality of life—A randomized controlled trial. Clinical Rehabilitation, 26(6), 493–501. https://doi.org/10.1177/0269215511426017CrossRefPubMed

Ryan, T., Enderby, P., & Rigby, A. S. (2006). A randomized controlled trial to evaluate intensity of community-based rehabilitation provision following stroke or hip fracture in old age. Clinical Rehabilitation, 20(2), 123–131. https://doi.org/10.1191/0269215506cr933oaCrossRefPubMed

Ellis, G., Rodger, J., McAlpine, C., & Langhorne, P. (2005). The impact of stroke nurse specialist input on risk factor modification: A randomised controlled trial. Age and Ageing, 34(4), 389–392. https://doi.org/10.1093/ageing/afi075CrossRefPubMed

Allen, K., Hazelett, S., Jarjoura, D., Hua, K., Wright, K., Weinhardt, J., & Kropp, D. (2009). A randomized trial testing the superiority of a postdischarge care management model for stroke survivors. Journal of Stroke and Cerebrovascular Diseases, 18(6), 443–452. https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.02.002CrossRefPubMedPubMedCentral

McManus, J. A., Craig, A., McAlpine, C., Langhorne, P., & Ellis, G. (2009). Does behaviour modification affect post-stroke risk factor control? Three-year follow-up of a randomized controlled trial. Clinical Rehabilitation, 23(2), 99–105. https://doi.org/10.1177/0269215508095874CrossRefPubMed

Carod-Artal, F. J., & Egido, J. A. (2009). Quality of life after stroke: The importance of a good recovery. Cerebrovascular Diseases, 27(Suppl 1), 204–214. https://doi.org/10.1159/000200461CrossRefPubMed

10.

Kim, E. S., Kim, J. W., Kang, H. J., Bae, K. Y., Kim, S. W., Kim, J. T., Park, M. S., Cho, K. H., & Kim, J. M. (2018). Longitudinal impact of depression on quality of life in stroke patients. Psychiatry Investigation, 15(2), 141–146. https://doi.org/10.30773/pi.2017.10.11CrossRefPubMed

11.

Pan, J. H., Song, X. Y., Lee, S. Y., & Kwok, T. (2008). Longitudinal analysis of quality of life for stroke survivors using latent curve models. Stroke, 39(10), 2795–2802. https://doi.org/10.1161/STROKEAHA.108.515460CrossRefPubMed

12.

Sadlonova, M., Wasser, K., Nagel, J., Weber-Kruger, M., Groschel, S., Uphaus, T., Liman, J., Hamann, G. F., Kermer, P., Groschel, K., Herrmann-Lingen, C., & Wachter, R. (2021). Health-related quality of life, anxiety and depression up to 12 months post-stroke: Influence of sex, age, stroke severity and atrial fibrillation—A longitudinal subanalysis of the Find-AFRANDOMISED trial. Journal of Psychosomatic Research, 142, 110353. https://doi.org/10.1016/j.jpsychores.2020.110353CrossRefPubMed

13.

Schindel, D., Schneider, A., Grittner, U., Jobges, M., & Schenk, L. (2019). Quality of life after stroke rehabilitation discharge: A 12-month longitudinal study. Disability and Rehabilitation. https://doi.org/10.1080/09638288.2019.1699173CrossRefPubMed

14.

Tse, T., Binte Yusoff, S. Z., Churilov, L., Ma, H., Davis, S., Donnan, G. A., Carey, L. M., & team, S. r. (2017). Increased work and social engagement is associated with increased stroke specific quality of life in stroke survivors at 3 months and 12 months post-stroke: A longitudinal study of an Australian stroke cohort. Topics in Stroke Rehabilitation, 24(6), 405–414. https://doi.org/10.1080/10749357.2017.1318339CrossRefPubMed

15.

van Mierlo, M. L., van Heugten, C. M., Post, M. W., Hajos, T. R., Kappelle, L. J., & Visser-Meily, J. M. (2016). Quality of life during the first two years post stroke: The restore4stroke cohort study. Cerebrovascular Diseases, 41(1–2), 19–26. https://doi.org/10.1159/000441197CrossRefPubMed

16.

Haley, W. E., Roth, D. L., Kissela, B., Perkins, M., & Howard, G. (2011). Quality of life after stroke: A prospective longitudinal study. Quality of Life Research, 20(6), 799–806. https://doi.org/10.1007/s11136-010-9810-6CrossRefPubMed

17.

Olaiya, M. T., Cadilhac, D. A., Kim, J., Nelson, M. R., Srikanth, V. K., Gerraty, R. P., Bladin, C. F., Fitzgerald, S. M., Phan, T., Frayne, J., & Thrift, A. G. (2017). Community-based intervention to improve cardiometabolic targets in patients with stroke: A randomized controlled trial. Stroke, 48(9), 2504–2510. https://doi.org/10.1161/STROKEAHA.117.017499CrossRefPubMed

18.

Olaiya, M. T., Cadilhac, D. A., Kim, J., Ung, D., Nelson, M. R., Srikanth, V. K., Bladin, C. F., Gerraty, R. P., Fitzgerald, S. M., Phan, T., Frayne, J., & Thrift, A. G. (2017). Effectiveness of an intervention to improve risk factor knowledge in patients with stroke: A randomized controlled trial. Stroke, 48(4), 1101–1103. https://doi.org/10.1161/STROKEAHA.116.016229CrossRefPubMed

19.

Olaiya, M. T., Cadilhac, D. A., Kim, J., Ung, D., Nelson, M. R., Srikanth, V. K., Bladin, C. F., Gerraty, R. P., Fitzgerald, S. M., Phan, T. G., Frayne, J., & Thrift, A. G. (2016). Nurse-led intervention to improve knowledge of medications in survivors of stroke or transient ischemic attack: A cluster randomized controlled trial. Frontiers in Neurology, 7, 205. https://doi.org/10.3389/fneur.2016.00205CrossRefPubMedPubMedCentral

20.

Olaiya, M. T., Kim, J., Nelson, M. R., Srikanth, V. K., Bladin, C. F., Gerraty, R. P., Fitzgerald, S. M., Phan, T., Frayne, J., Cadilhac, D. A., Thrift, A. G., & investigators, S. (2017). Effectiveness of a shared team approach between nurses and doctors for improved risk factor management in survivors of stroke: A cluster randomized controlled trial. European Journal of Neurology, 24(7), 920–928. https://doi.org/10.1111/ene.13306CrossRefPubMed

21.

Thrift, A. G., Olaiya, M. T., Phan, T. G., Cadilhac, D. A., Nelson, M. R., Srikanth, V. K., & Investigators, S. (2015). Statistical analysis plan (SAP) for shared team approach between nurses and doctors for improved risk factor management (STANDFIRM): A randomised controlled trial. International Journal of Stroke, 10(5), 770–772. https://doi.org/10.1111/ijs.12482CrossRefPubMed

22.

Thrift, A. G., Srikanth, V. K., Nelson, M. R., Kim, J., Fitzgerald, S. M., Gerraty, R. P., Bladin, C. F., Phan, T. G., & Cadilhac, D. A. (2014). Risk factor management in survivors of stroke: A double-blind, cluster-randomized, controlled trial. International Journal of Stroke, 9(5), 652–657. https://doi.org/10.1111/j.1747-4949.2012.00933.xCrossRefPubMed

23.

Thayabaranathan, T., Cadilhac, D. A., Srikanth, V. K., Fitzgerald, S. M., Evans, R. G., Kim, J., Gerraty, R. P., Phan, T. G., Bladin, C. F., Nelson, M. R., Frayne, J. H., & Thrift, A. G. (2016). Maximizing patient recruitment and retention in a secondary stroke prevention clinical trial: Lessons learned from the STAND FIRM study. Journal of Stroke and Cerebrovascular Diseases, 25(6), 1371–1380. https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.02.020CrossRefPubMed

24.

Hawthorne, G., Richardson, J., & Osborne, R. (1999). The assessment of quality of life (AQoL) instrument: A psychometric measure of health-related quality of life. Quality of Life Research, 8(3), 209–224. https://doi.org/10.1023/a:1008815005736CrossRefPubMed

25.

Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta Psychiatrica Scandavian, 67(6), 361–370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.xCrossRef

26.

Harwood, R. H., Rogers, A., Dickinson, E., & Ebrahim, S. (1994). Measuring handicap: The London Handicap Scale, a new outcome measure for chronic disease. Quality in Health Care, 3(1), 11–16. https://doi.org/10.1136/qshc.3.1.11CrossRefPubMedPubMedCentral

27.

Sturm, J. W., Osborne, R. H., Dewey, H. M., Donnan, G. A., Macdonell, R. A., & Thrift, A. G. (2002). Brief comprehensive quality of life assessment after stroke: The assessment of quality of life instrument in the North East Melbourne Stroke Incidence Study (NEMESIS). Stroke, 33(12), 2888–2894. https://doi.org/10.1161/01.str.0000040407.44712.c7CrossRefPubMed

28.

Centre for Health Economics, M. U. (2015, May 26). Stata algorithm for AQoL-4D utility model (with missing values). Retrieved May 19 from https://www.aqol.com.au/index.php/scoring-algorithms?id=86

29.

White, J., Magin, P., Attia, J., Sturm, J., McElduff, P., & Carter, G. (2016). Predictors of health-related quality of life in community-dwelling stroke survivors: A cohort study. Family Practice, 33(4), 382–387. https://doi.org/10.1093/fampra/cmw011CrossRefPubMed

30.

Cumming, T. B., Churilov, L., Collier, J., Donnan, G., Ellery, F., Dewey, H., Langhorne, P., Lindley, R. I., Moodie, M., Thrift, A. G., Bernhardt, J., & group, A. T. C. (2019). Early mobilization and quality of life after stroke: Findings from AVERT. Neurology, 93(7), e717–e728. https://doi.org/10.1212/WNL.0000000000007937CrossRefPubMedPubMedCentral

31.

Clarke, P. J., Lawrence, J. M., & Black, S. E. (2000). Changes in quality of life over the first year after stroke: Findings from the Sunnybrook Stroke Study. Journal of Stroke and Cerebrovascular Diseases, 9(3), 121–127. https://doi.org/10.1053/jscd.2000.5868CrossRefPubMed

32.

Kim, P., Warren, S., Madill, H., & Hadley, M. (1999). Quality of life of stroke survivors. Quality of Life Research, 8(4), 293–301. https://doi.org/10.1023/a:1008927431300CrossRefPubMed

33.

Kauhanen, M. L., Korpelainen, J. T., Hiltunen, P., Nieminen, P., Sotaniemi, K. A., & Myllyla, V. V. (2000). Domains and determinants of quality of life after stroke caused by brain infarction. Archives of Physical Medicine and Rehabilitation, 81(12), 1541–1546. https://doi.org/10.1053/apmr.2000.9391CrossRefPubMed

34.

Group, U. S. C. Repeated Measures Analysis with Stata. Retrieved January 28 from https://stats.idre.ucla.edu/stata/seminars/repeated-measures-analysis-with-stata/

35.

StataCorp. Stata statistical software: Release 16. StataCorp LLC; 2019.

36.

Fu, V., Weatherall, M., McPherson, K., Taylor, W., McRae, A., Thomson, T., Gommans, J., Green, G., Harwood, M., Ranta, A., Hanger, C., Riley, J., & McNaughton, H. (2020). Taking charge after stroke: A randomized controlled trial of a person-centered, self-directed rehabilitation intervention. International Journal of Stroke. https://doi.org/10.1177/1747493020915144CrossRefPubMedPubMedCentral

37.

Pucciarelli, G., Vellone, E., Savini, S., Simeone, S., Ausili, D., Alvaro, R., Lee, C. S., & Lyons, K. S. (2017). Roles of changing physical function and caregiver burden on quality of life in stroke: A longitudinal dyadic analysis. Stroke, 48(3), 733–739. https://doi.org/10.1161/STROKEAHA.116.014989CrossRefPubMed

38.

Sturm, J. W., Donnan, G. A., Dewey, H. M., Macdonell, R. A., Gilligan, A. K., Srikanth, V., & Thrift, A. G. (2004). Quality of life after stroke: The North East Melbourne Stroke Incidence Study (NEMESIS). Stroke, 35(10), 2340–2345. https://doi.org/10.1161/01.STR.0000141977.18520.3bCrossRefPubMed

39.

Bernhardt, J., Hayward, K. S., Kwakkel, G., Ward, N. S., Wolf, S. L., Borschmann, K., Krakauer, J. W., Boyd, L. A., Carmichael, S. T., Corbett, D., & Cramer, S. C. (2017). Agreed definitions and a shared vision for new standards in stroke recovery research: The stroke recovery and rehabilitation roundtable taskforce. International Journal of Stroke, 12(5), 444–450. https://doi.org/10.1177/1747493017711816CrossRefPubMed

40.

Hawthorne, G., & Osborne, R. (2005). Population norms and meaningful differences for the Assessment of Quality of Life (AQoL) measure. Australian and New Zealand Journal of Public Health, 29(2), 136–142. https://doi.org/10.1111/j.1467-842x.2005.tb00063.xCrossRefPubMed

41.

Williams, L. S., Bakas, T., Brizendine, E., Plue, L., Tu, W., Hendrie, H., & Kroenke, K. (2006). How valid are family proxy assessments of stroke patients’ health-related quality of life? Stroke, 37(8), 2081–2085. https://doi.org/10.1161/01.STR.0000230583.10311.9fCrossRefPubMed

42.

Pedersen, S. G., Friborg, O., Heiberg, G. A., Arntzen, C., Stabel, H. H., Thrane, G., Nielsen, J. F., & Anke, A. (2020). Stroke-Specific Quality of Life one-year post-stroke in two Scandinavian country-regions with different organisation of rehabilitation services: A prospective study. Disability and Rehabilitation. https://doi.org/10.1080/09638288.2020.1753830CrossRefPubMed

43.

Twardzik, E., Clarke, P., Elliott, M. R., Haley, W. E., Judd, S., & Colabianchi, N. (2019). Neighborhood socioeconomic status and trajectories of physical health-related quality of life among stroke survivors. Stroke, 50(11), 3191–3197. https://doi.org/10.1161/STROKEAHA.119.025874CrossRefPubMedPubMedCentral

44.

Phan, H. T., Gall, S. L., Blizzard, C. L., Lannin, N. A., Thrift, A. G., Anderson, C. S., Kim, J., Grimley, R. S., Castley, H. C., Kilkenny, M. F., Cadilhac, D. A., & AuScr Consortium, S. I. (2021). Sex differences in quality of life after stroke were explained by patient factors, not clinical care: Evidence from the Australian Stroke Clinical Registry. European Journal of Neurology, 28(2), 469–478. https://doi.org/10.1111/ene.14531CrossRef

45.

Katona, M., Schmidt, R., Schupp, W., & Graessel, E. (2015). Predictors of health-related quality of life in stroke patients after neurological inpatient rehabilitation: A prospective study. Health and Quality of Life Outcomes, 13, 58. https://doi.org/10.1186/s12955-015-0258-9CrossRefPubMedPubMedCentral

46.

Dorman, P. J., Waddell, F., Slattery, J., Dennis, M., & Sandercock, P. (1997). Are proxy assessments of health status after stroke with the EuroQol questionnaire feasible, accurate, and unbiased? Stroke, 28(10), 1883–1887. https://doi.org/10.1161/01.str.28.10.1883CrossRefPubMed

47.

Oczkowski, C., & O’Donnell, M. (2010). Reliability of proxy respondents for patients with stroke: A systematic review. Journal of Stroke and Cerebrovascular Diseases, 19(5), 410–416. https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.08.002CrossRefPubMed

Titel: Quality of life after stroke: a longitudinal analysis of a cluster randomized trial
Auteurs: Zhomart Orman
Amanda G. Thrift
Muideen T. Olaiya
David Ung
Dominique A. Cadilhac
Thanh Phan
Mark R. Nelson
Velandai K. Srikanth
Jason Vuong
Christopher F. Bladin
Richard P. Gerraty
Sharyn M. Fitzgerald
Judith Frayne
Joosup Kim
the STANDFIRM (Shared Team Approach between Nurses and Doctors For Improved Risk factor Management) Investigators
Publicatiedatum: 24-01-2022
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 8/2022
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-021-03066-y

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Abstract

Purpose

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Results

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