For care innovation and disruption, there are challenges along the way to achieving a real shift in health care. Implementation of Positive Health requires a number of preconditions, and it is important that Positive Health is included in the Dutch Government’s National Policy Document on Public Health. The Institute for Positive Health (iPH) contributes to the further development of the Positive Health concept, in the areas of policy, practice, research and education, and looks at how Positive Health relates to other broad health concepts and working methods. The concept of Positive Health is also subject to criticism. Also from that perspective, there is ongoing attention for the further substantiation and scientific value of Positive Health. Further embedding Positive Health in general medical practices and beyond may also contribute to designing meaningful care. Positive Health, therefore, should become an essential element of the training and education of future care professionals.