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20-04-2024

Influence of frailty status on the health-related quality of life in older patients with chronic low back pain: a retrospective observational study

Auteurs: Hee Jung Kim, Byongnam Jun, Hee Won Lee, Shin Hyung Kim

Gepubliceerd in: Quality of Life Research

Abstract

Purpose

Understanding the influence of frailty on health-related quality of life (HRQoL) in older individuals experiencing chronic low back pain can provide valuable insights into the impact of frailty. Therefore, the aim of our study is to assess how different frailty statuses among older outpatients with chronic low back pain affect their HRQoL.

Methods

Patients aged 60 and above with chronic low back pain were recruited from March 2022 to February 2023. Frailty was assessed via the frailty phenotype questionnaire, and HRQoL was evaluated using the EQ-5D-5L. Multiple regression models were used to explore the influence of frailty status on the EQ-5D-5L index and EQ-VAS. Logistic regression was used to determine odds ratios for the impact of frailty status on belonging to the lowest EQ-5D-5L index quartile.

Results

A total of 1,054 participants were classified into robust (29.8%), pre-frail (47.7%), and frail (22.5%) groups. Frailty was significantly associated with declining HRQoL. Pre-frail and frail statuses were inversely linked to the EQ-5D-5L index, with significantly higher odds of scoring in the lowest quartile compared to robust individuals. Stratification analysis identified sex as an effect modifier, emphasizing a more substantial association between frailty and the lowest EQ-5D-5L index quartile in female patients.

Conclusions

A significant association exists between frailty and reduced HRQoL in patients with chronic low back pain. This association was predominant in female patients. Furthermore, considering the dynamic nature of frailty, early detection and effective interventions targeting pre-frailty are essential to delaying the transition to full frailty and improving HRQoL.

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Kim, S., Won, C. W., Kim, B. S., Kim, S., Yoo, J., Byun, S., Jang, H. C., Cho, B. L., Son, S. J., Lee, J. H., Park, Y. S., Choi, K. M., Kim, H. J., & Lee, S. G. (2018). EuroQol visual analogue scale (EQ-VAS) as a predicting tool for frailty in older korean adults: The Korean frailty an aging cohort study (KFACS). The journal of nutrition, health & aging, 22(10), 1275–1280. https://doi.org/10.1007/s12603-018-1077-6CrossRef

Park, D., & Kim, H. S. (2022). The factors affecting frailty among the elderly in Korea: A study using the frailty cohort. International journal of environmental research and public health, 20(1), 670. https://doi.org/10.3390/ijerph20010670CrossRefPubMedPubMedCentral

Hoogendijk, E. O., Afilalo, J., Ensrud, K. E., Kowal, P., Onder, G., & Fried, L. P. (2019). Frailty: Implications for clinical practice and public health. Lancet (London, England), 394(10206), 1365–1375. https://doi.org/10.1016/S0140-6736(19)31786-6CrossRefPubMed

Chang, Y. W., Chen, W. L., Lin, F. G., Fang, W. H., Yen, M. Y., Hsieh, C. C., & Kao, T. W. (2012). Frailty and its impact on health-related quality of life: A cross-sectional study on elder community-dwelling preventive health service users. PLoS ONE, 7(5), e38079. https://doi.org/10.1371/journal.pone.0038079CrossRefPubMedPubMedCentral

Ensrud, K. E., Ewing, S. K., Taylor, B. C., Fink, H. A., Stone, K. L., Cauley, J. A., Tracy, J. K., Hochberg, M. C., Rodondi, N., Cawthon, P. M., Study of Osteoporotic Fractures Research Group. (2007). Frailty and risk of falls, fracture, and mortality in older women: The study of osteoporotic fractures. The journals of gerontology. Series A, Biological sciences and medical sciences, 62(7), 744–751. https://doi.org/10.1093/gerona/62.7.744CrossRefPubMed

Soysal, P., Veronese, N., Thompson, T., Kahl, K. G., Fernandes, B. S., Prina, A. M., Solmi, M., Schofield, P., Koyanagi, A., Tseng, P. T., Lin, P. Y., Chu, C. S., Cosco, T. D., Cesari, M., Carvalho, A. F., & Stubbs, B. (2017). Relationship between depression and frailty in older adults: A systematic review and meta-analysis. Ageing research reviews, 36, 78–87. https://doi.org/10.1016/j.arr.2017.03.005CrossRefPubMed

Sousa-Fraguas, M. C., Rodríguez-Fuentes, G., & Conejo, N. M. (2022). Frailty and cognitive impairment in Parkinson’s disease: A systematic review. Neurological sciences : Official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 43(12), 6693–6706. https://doi.org/10.1007/s10072-022-06347-7CrossRefPubMed

Kojima, G., Iliffe, S., & Walters, K. (2018). Frailty index as a predictor of mortality: A systematic review and meta-analysis. Age and ageing, 47(2), 193–200. https://doi.org/10.1093/ageing/afx162CrossRefPubMed

Etxeberria, I., Urdaneta, E., & Galdona, N. (2019). Factors associated with health-related quality of life (HRQoL): Differential patterns depending on age. Quality of life research : An international journal of quality of life aspects of treatment, care and rehabilitation, 28(8), 2221–2231. https://doi.org/10.1007/s11136-019-02182-0CrossRefPubMed

10.

Rejeski, W. J., & Mihalko, S. L. (2001). Physical activity and quality of life in older adults. The journals of gerontology. Series A, Biological sciences and medical sciences, 56(2), 23–35. https://doi.org/10.1093/gerona/56.suppl_2.23CrossRefPubMed

11.

Masel, M. C., Graham, J. E., Reistetter, T. A., Markides, K. S., & Ottenbacher, K. J. (2009). Frailty and health related quality of life in older Mexican Americans. Health and quality of life outcomes, 7, 70. https://doi.org/10.1186/1477-7525-7-70CrossRefPubMedPubMedCentral

12.

Coyle, P. C., Sions, J. M., Velasco, T., & Hicks, G. E. (2015). Older adults with chronic low back pain: A clinical population vulnerable to frailty? The Journal of frailty & aging, 4(4), 188–190. https://doi.org/10.14283/jfa.2015.75CrossRef

13.

Rudy, T. E., Weiner, D. K., Lieber, S. J., Slaboda, J., & Boston, R. J. (2007). The impact of chronic low back pain on older adults: A comparative study of patients and controls. Pain, 131(3), 293–301. https://doi.org/10.1016/j.pain.2007.01.012CrossRefPubMedPubMedCentral

14.

Leopoldino, A. A. O., Megale, R. Z., Diz, J. B. M., Moreira, B. S., Felício, D. C., Queiroz, B. Z., Bastone, A. C., Ferreira, M. L., & Pereira, L. S. M. (2021). Influence of frailty status on pain, disability, and quality of life in older adults with acute low back pain: Results from the back complaints in the elders (BACE-Brazil) study. Canadian journal on aging = La revue canadienne du vieillissement, 40(3), 367–375. https://doi.org/10.1017/S0714980820000288CrossRefPubMed

15.

Kim, S., Kim, M., Jung, H. W., & Won, C. W. (2020). Development of a frailty phenotype questionnaire for use in screening community-dwelling older adults. Journal of the American Medical Directors Association, 21(5), 660–664. https://doi.org/10.1016/j.jamda.2019.08.028CrossRefPubMed

16.

Cedraschi, C., Luthy, C., Allaz, A. F., Herrmann, F. R., & Ludwig, C. (2016). Low back pain and health-related quality of life in community-dwelling older adults. European spine journal, 25(9), 2822–2832. https://doi.org/10.1007/s00586-016-4483-7CrossRefPubMed

17.

Kim, S. H., Ahn, J., Ock, M., Shin, S., Park, J., Luo, N., & Jo, M. W. (2016). The EQ-5D-5L valuation study in Korea. Quality of life research, 25(7), 1845–1852. https://doi.org/10.1007/s11136-015-1205-2CrossRefPubMed

18.

Nixon, A. C., Bampouras, T. M., Pendleton, N., Mitra, S., Brady, M. E., & Dhaygude, A. P. (2019). Frailty is independently associated with worse health-related quality of life in chronic kidney disease: A secondary analysis of the frailty assessment in chronic kidney disease study. Clinical kidney journal, 13(1), 85–94. https://doi.org/10.1093/ckj/sfz038CrossRefPubMedPubMedCentral

19.

Collard, R. M., Boter, H., Schoevers, R. A., & Oude Voshaar, R. C. (2012). Prevalence of frailty in community-dwelling older persons: A systematic review. Journal of the American Geriatrics Society, 60(8), 1487–1492. https://doi.org/10.1111/j.1532-5415.2012.04054.xCrossRefPubMed

20.

Di Iorio, A., Abate, M., Guralnik, J. M., Bandinelli, S., Cecchi, F., Cherubini, A., Corsonello, A., Foschini, N., Guglielmi, M., Lauretani, F., Volpato, S., Abate, G., & Ferrucci, L. (2007). From chronic low back pain to disability, a multifactorial mediated pathway: The InCHIANTI study. Spine, 32(26), E809–E815. https://doi.org/10.1097/BRS.0b013e31815cd422CrossRefPubMedPubMedCentral

21.

Rockwood, K., & Mitnitski, A. (2007). Frailty in relation to the accumulation of deficits. The journals of gerontology. Series A, Biological sciences and medical sciences, 62(7), 722–727. https://doi.org/10.1093/gerona/62.7.722CrossRefPubMed

22.

Stubbs, B., Binnekade, T. T., Soundy, A., Schofield, P., Huijnen, I. P., & Eggermont, L. H. (2013). Are older adults with chronic musculoskeletal pain less active than older adults without pain? a systematic review and meta-analysis. Pain medicine (Malden, Mass.), 14(9), 1316–1331. https://doi.org/10.1111/pme.12154CrossRefPubMed

23.

Otones, P., García, E., Sanz, T., & Pedraz, A. (2020). A physical activity program versus usual care in the management of quality of life for pre-frail older adults with chronic pain: Randomized controlled trial. BMC geriatrics, 20(1), 396. https://doi.org/10.1186/s12877-020-01805-3CrossRefPubMedPubMedCentral

24.

Fillit, H., & Butler, R. N. (2009). The frailty identity crisis. Journal of the American Geriatrics Society, 57(2), 348–352. https://doi.org/10.1111/j.1532-5415.2008.02104.xCrossRefPubMed

25.

Semeru, G. M., & Halim, M. S. (2019). Acceptance versus catastrophizing in predicting quality of life in patients with chronic low back pain. The Korean journal of pain, 32(1), 22–29. https://doi.org/10.3344/kjp.2019.32.1.22CrossRefPubMedPubMedCentral

26.

Jiménez-Zazo, F., Navarrete-Villanueva, D., Gómez-Cabello, A., Romero-Blanco, C., Cabanillas, E., Pérez-Gómez, J., Calonge-Pascual, S., Ara, I., Vicente-Rodríguez, G., & Aznar, S. (2022). Psychosocial factors related to physical activity in frail and prefrail elderly people. BMC geriatrics, 22(1), 407. https://doi.org/10.1186/s12877-022-03042-2CrossRefPubMedPubMedCentral

27.

Zeidan, R. S., McElroy, T., Rathor, L., Martenson, M. S., Lin, Y., & Mankowski, R. T. (2023). Sex differences in frailty among older adults. Experimental gerontology, 184, 112333. https://doi.org/10.1016/j.exger.2023.112333CrossRefPubMed

28.

Jyväkorpi, S. K., Lindström, M., Suominen, M. H., Kautiainen, H., Salminen, K., Niskanen, R. T., Pitkälä, K. H., & Roitto, H. M. (2022). Relationship between frailty, nutrition, body composition, quality of life, and gender in institutionalized older people. Aging clinical and experimental research, 34(6), 1357–1363. https://doi.org/10.1007/s40520-022-02077-0CrossRefPubMedPubMedCentral

29.

Otones Reyes, P., García Perea, E., Rico Blázquez, M., & Pedraz Marcos, A. (2020). Prevalence and correlates of frailty in community-dwelling older adults with chronic pain: A cross-sectional study. Pain management nursing, 21(6), 530–535. https://doi.org/10.1016/j.pmn.2020.05.009CrossRefPubMed

30.

Acosta-Benito, M. A., & Sevilla-Machuca, I. (2016). Using prefrailty to detect early disability. Journal of family & community medicine, 23(3), 140–144. https://doi.org/10.4103/2230-8229.189106CrossRef

31.

Serra-Prat, M., Sist, X., Saiz, A., Jurado, L., Domenich, R., Roces, A., & Papiol, M. (2016). Clinical and functional characterization of pre-frailty among elderly patients consulting primary care centres. The journal of nutrition, health & aging, 20(6), 653–658. https://doi.org/10.1007/s12603-016-0684-3CrossRef

32.

Haider, S., Grabovac, I., & Dorner, T. E. (2019). Effects of physical activity interventions in frail and prefrail community-dwelling people on frailty status, muscle strength, physical performance and muscle mass-a narrative review. Wiener klinische Wochenschrift, 131(11–12), 244–254. https://doi.org/10.1007/s00508-019-1484-7CrossRefPubMedPubMedCentral

33.

Andrasinova, T., Adamova, B., Buskova, J., Kerkovsky, M., Jarkovsky, J., & Bednarik, J. (2018). Is there a correlation between degree of radiologic lumbar spinal stenosis and its clinical manifestation? Clinical spine surgery, 31(8), E403–E408. https://doi.org/10.1097/BSD.0000000000000681CrossRefPubMed

Titel: Influence of frailty status on the health-related quality of life in older patients with chronic low back pain: a retrospective observational study
Auteurs: Hee Jung Kim
Byongnam Jun
Hee Won Lee
Shin Hyung Kim
Publicatiedatum: 20-04-2024
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-024-03658-4

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Abstract

Purpose

Methods

Results

Conclusions

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