Top

Quality of Life Research

Gepubliceerd in:

01-07-2016

Health-related quality of life questionnaire for polycystic ovary syndrome (PCOSQ-50): development and psychometric properties

Auteurs: Fatemeh Nasiri-Amiri, Fahimeh Ramezani Tehrani, Masoumeh Simbar, Ali Montazeri, Reza Ali Mohammadpour

Gepubliceerd in: Quality of Life Research | Uitgave 7/2016

Abstract

Purpose

The determinants of the health-related quality of life of women with polycystic ovary syndrome are not fully understood. The aim of this study was to develop a comprehensive instrument to assess the health-related quality of life of Iranian women with PCOS and to assess its psychometric properties.

Methods

We used a mixed-method, sequential, exploratory design including both qualitative [in-depth interview to define the components of health-related quality of life questionnaire (PCOSQ)] and quantitative approaches (to assess the psychometric properties of PCOSQ).

Results

A preliminary questionnaire was developed including 147 items which emerged from the qualitative phase of the study. Considering the optimum cutoff points for content validity ratio (CVR), content validity index (CVI), and impact score, items of the preliminary questionnaire were reduced from 147 to 88 items. Finally, by excluding highly correlated items using the exploratory factor analysis, a 50-item questionnaire was obtained. The Kaiser criteria (eigenvalues >1) and Scree plot tests demonstrated that six factors were optimum with an estimated 47.3 % of variance. Assessment of the psychometric properties of the questionnaire demonstrated a mean CVI = 0.92, CVR = 0.91, Cronbach’s alpha for whole questionnaire = 0.88 (0.61–0.88 for subscales), Spearman’s correlation coefficients of test–retest = 0.75, and the intra-class correlation coefficient for the PCOS questionnaire subscales ranging from 0.57 to 0.88. Eventually the final questionnaire included 50 items in six domains, ‘psychosocial and emotional,’ ‘fertility,’ ‘sexual function,’ ‘obesity and menstrual disorders,’ ‘hirsutism,’ and ‘coping’ and rated on a 5-point Likert scale.

Conclusion

The PCOSQ-50 is a valid and reliable instrument for the assessment of quality of life of women with PCOS, capable of assessing some obscure aspects overlooked by previous HRQL questionnaires.

vorige artikel Satisfaction with life in adults with Marfan syndrome (MFS): associations with health-related consequences of MFS, pain, fatigue, and demographic factors

volgende artikel The PROMIS FatigueFM Profile: a self-report measure of fatigue for use in fibromyalgia

Fauser, B. C., Tarlatzis, B. C., Rebar, R. W., Legro, R. S., Balen, A. H., Lobo, R., et al. (2012). Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): The Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Fertility and Sterility, 97(1), 28–38.CrossRefPubMed

Tehrani, F. R., Rashidi, H., & Azizi, F. (2011). The prevalence of idiopathic hirsutism and polycystic ovary syndrome in the Tehran Lipid and Glucose Study. Reproductive Biology and Endocrinology, 9, 144.CrossRefPubMedPubMedCentral

Tehrani, F. R., Simbar, M., Tohidi, M., Hosseinpanah, F., & Azizi, F. (2011). The prevalence of polycystic ovary syndrome in a community sample of Iranian population: Iranian PCOS prevalence study. Reproductive Biology and Endocrinology, 9, 39.CrossRefPubMedPubMedCentral

Kitzinger, C., & Willmott, J. (2002). ‘The thief of womanhood’: Women’s experience of polycystic ovarian syndrome. Social Science and Medicine, 54(3), 349–361.CrossRefPubMed

Snyder, B. S. (2006). The lived experience of women diagnosed with polycystic ovary syndrome. Journal of Obstetric, Gynecologic, and Neonatal Nursing, 35(3), 385–392.CrossRefPubMed

Solomon, C. G. (1999). The epidemiology of polycystic ovary syndrome. Prevalence and associated disease risks. Endocrinology and Metabolism Clinics of North America, 28(2), 247–263.CrossRefPubMed

Azziz, R., Woods, K. S., Reyna, R., Key, T. J., Knochenhauer, E. S., & Yildiz, B. O. (2004). The prevalence and features of the polycystic ovary syndrome in an unselected population. Journal of Clinical Endocrinology and Metabolism, 89(6), 2745–2749.CrossRefPubMed

Carmina, E., & Lobo, R. A. (1999). Polycystic ovary syndrome (PCOS): Arguably the most common endocrinopathy is associated with significant morbidity in women. Journal of Clinical Endocrinology and Metabolism, 84(6), 1897–1899.CrossRefPubMed

Ching, H. L., Burke, V., & Stuckey, B. G. (2007). Quality of life and psychological morbidity in women with polycystic ovary syndrome: Body mass index, age and the provision of patient information are significant modifiers. Clinical Endocrinology (Oxf), 66(3), 373–379.CrossRef

10.

Testa, M. A., & Simonson, D. C. (1996). Assesment of quality-of-life outcomes. New England Journal of Medicine, 334(13), 835–840.CrossRefPubMed

11.

Jones, G. L., Hall, J. M., Balen, A. H., & Ledger, W. L. (2008). Health-related quality of life measurement in women with polycystic ovary syndrome: A systematic review. Human Reproduction Update, 14(1), 15–25.CrossRefPubMed

12.

Barth, J. H., Catalan, J., Cherry, C. A., & Day, A. (1993). Psychological morbidity in women referred for treatment of hirsutism. Journal of Psychosomatic Research, 37(6), 615–619.CrossRefPubMed

13.

Sonino, N., Fava, G. A., Mani, E., Belluardo, P., & Boscaro, M. (1993). Quality of life of hirsute women. Postgraduate Medical Journal, 69(809), 186–189.CrossRefPubMedPubMedCentral

14.

Mallon, E., Newton, J. N., Klassen, A., Stewart-Brown, S. L., Ryan, T. J., & Finlay, A. Y. (1999). The quality of life in acne: A comparison with general medical conditions using generic questionnaires. British Journal of Dermatology, 140(4), 672–676.CrossRefPubMed

15.

Hashemi, S., Ramezani Tehrani, F., Farahmand, M., & Bahri Khomami, M. (2014). Association of PCOS and its clinical signs with sexual function among Iranian women affected by PCOS. The Journal of Sexual Medicine, 11(10), 2508–2514.CrossRefPubMed

16.

Khomami, M. B., Tehrani, F. R., Hashemi, S., Farahmand, M., & Azizi, F. (2015). Of PCOS symptoms, hirsutism has the most significant impact on the quality of life of Iranian women. PLoS ONE, 10(4), e0123608.CrossRefPubMedPubMedCentral

17.

Paulson, J. D., Haarmann, B. S., Salerno, R. L., & Asmar, P. (1988). An investigation of the relationship between emotional maladjustment and infertility. Fertility and Sterility, 49(2), 258–262.CrossRefPubMed

18.

Downey, J., Yingling, S., McKinney, M., Husami, N., Jewelewicz, R., & Maidman, J. (1989). Mood disorders, psychiatric symptoms, and distress in women presenting for infertility evaluation. Fertility and Sterility, 52(3), 425–432.CrossRefPubMed

19.

Guyatt, G. H., Feeny, D. H., & Patrick, D. L. (1993). Measuring health-related quality of life. Annals of Internal Medicine, 118(8), 622–629.CrossRefPubMed

20.

Cronin, L., Guyatt, G., Griffith, L., Wong, E., Azziz, R., Futterweit, W., et al. (1998). Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS). Journal of Clinical Endocrinology and Metabolism, 83(6), 1976–1987.PubMed

21.

Barnard, L., Ferriday, D., Guenther, N., Strauss, B., Balen, A. H., & Dye, L. (2007). Quality of life and psychological well being in polycystic ovary syndrome. Human Reproduction, 22(8), 2279–2286.CrossRefPubMed

22.

Malik-Aslam, A., Reaney, M. D., & Speight, J. (2010). The suitability of polycystic ovary syndrome-specific questionnaires for measuring the impact of PCOS on quality of life in clinical trials. Value Health, 13(4), 440–446.CrossRefPubMed

23.

Guyatt, G., Weaver, B., Cronin, L., Dooley, J. A., & Azziz, R. (2004). Health-related quality of life in women with polycystic ovary syndrome, a self-administered questionnaire, was validated. Journal of Clinical Epidemiology, 57(12), 1279–1287.CrossRefPubMed

24.

McCook, J. G., Reame, N. E., & Thatcher, S. S. (2005). Health-related quality of life issues in women with polycystic ovary syndrome. Journal of Obstetric, Gynecologic, and Neonatal Nursing, 34(1), 12–20.CrossRefPubMed

25.

Jones, G. L., Benes, K., Clark, T. L., Denham, R., Holder, M. G., Haynes, T. J., et al. (2004). The Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (PCOSQ): A validation. Human Reproduction, 19(2), 371–377.CrossRefPubMed

26.

Elsenbruch, S., Hahn, S., Kowalsky, D., Offner, A. H., Schedlowski, M., Mann, K., & Janssen, O. E. (2003). Quality of life, psychosocial well-being, and sexual satisfaction in women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 88(12), 5801–5807.CrossRefPubMed

27.

Drosdzol, A., Skrzypulec, V., Mazur, B., & Pawlinska-Chmara, R. (2007). Quality of life and marital sexual satisfaction in women with polycystic ovary syndrome. Folia Histochemica et Cytobiologica, 45(Suppl 1), S93–S97.PubMed

28.

Ivankova, Nataliya V., Creswell, J. W., & Stick, S. L. (2006). Using mixed-methods sequential explanatory design: From theory to practice. Field Methods, 18(1), 3–20.CrossRef

29.

Nasiri Amiri, F., Ramezani Tehrani, F., Simbar, M., Mohammadpour Thamtan, R. A., & Shiva, N. (2014). Female gender scheme is disturbed by polycystic ovary syndrome: A qualitative study from Iran. Iranian Red Crescent Medical Journal, 16(2), e12423.CrossRefPubMedPubMedCentral

30.

Corbin, J., & Strauss, A. (2008). Basics of qualitative research, techniques and procedures for developing grounded theory. USA: Sage Publication.

31.

Waltz, C. B. R. (1981). Nursing research: Design, statistics and computer analysis. Philadelphia: FA Davis Company.

32.

Hyrkas, K., Appelqvist-Schmidlechner, K., & Oksa, L. (2003). Validating an instrument for clinical supervision using an expert panel. International Journal of Nursing Studies, 40(6), 619–625.CrossRefPubMed

33.

Lawshe, C. (1975). A quantitative approach to content validity. Personnel Psychology, 28, 563–575.CrossRef

34.

Lacasse, Y., Godbout, C., & Series, F. (2002). Health-related quality of life in obstructive sleep apnoea. European Respiratory Journal, 19(3), 499–503.CrossRefPubMed

35.

Munro, B. (2005). Statistical methods for health care research. Philadelphia: Lippincott, Williams & Wilkins.

36.

Velicer, W., Eaton, C. A., & Fava, J. L. (2000). Problems and solutions in human assessment. Berlin: Springer, US.

37.

Montazeri, A., Goshtasebi, A., Vahdaninia, M., & Gandek, B. (2005). The Short Form Health Survey (SF-36): Translation and validation study of the Iranian version. Quality of Life Research, 14(3), 875–882.CrossRefPubMed

38.

Bland, J. M., & Altman, D. G. (1997). Cronbach’s alpha. BMJ, 314(7080), 572.CrossRefPubMedPubMedCentral

39.

Burns, N., & Grove, S. K. (2005). The practice of nursing research: Conduct, critique and utilization. Philadelphia: Elsevier Saunders Co.

40.

Landis, J. R., & Koch, G. G. (1977). The measurement of observer agreement for categorical data. Biometrics, 33(1), 159–174.CrossRefPubMed

41.

Nulty, D. D. (2008). The adequacy of response rates to online and paper surveys: What can be done? Assessment & Evaluation in Higher Education, 33(3), 301–314.CrossRef

42.

Veras, A. B., Bruno, R. V., de Avila, M. A., & Nardi, A. E. (2011). Sexual dysfunction in patients with polycystic ovary syndrome: Clinical and hormonal correlations. Comprehensive Psychiatry, 52(5), 486–489.CrossRefPubMed

43.

Stovall, D. W., Scriver, J. L., Clayton, A. H., Williams, C. D., & Pastore, L. M. (2012). Sexual function in women with polycystic ovary syndrome. The Journal of Sexual Medicine, 9(1), 224–230.CrossRefPubMedPubMedCentral

44.

Esposito, K., Ciotola, M., Giugliano, F., Bisogni, C., Schisano, B., Autorino, R., et al. (2007). Association of body weight with sexual function in women. International Journal of Impotence Research, 19(4), 353–357.CrossRefPubMed

45.

Brady, C., Shaymaa, M., & Mousa S. (2009). Polycystic ovary syndrome and its impact on women’s quality of life: More than just an endocrine disorder. Drug, Healthcare and Patient Safety, 1, 9–15.PubMedPubMedCentral

46.

Dewailly, D., Lujan, M. E., Carmina, E., Cedars, M. I., Laven, J., Norman, R. J., & Escobar-Morreale, H. F. (2014). Definition and significance of polycystic ovarian morphology: A task force report from the Androgen Excess and Polycystic Ovary Syndrome Society. Human Reproduction Update, 20(3), 334–352.CrossRefPubMed

47.

Shen, Y., Wang, T., Zhou, C., Wang, X., Ding, X., Tian, S., et al. (2012). Prevalence of acne vulgaris in Chinese adolescents and adults: A community-based study of 17,345 subjects in six cities. Acta Dermato Venereologica, 92(1), 40–44.CrossRefPubMed

48.

Wei, S., Schmidt, M., Dwyer, T., Norman, R. J., & Venn, A. J. (2009). Obesity and menstrual irregularity: Associations with SHBG, testosterone, and insulin. Obesity (Silver Spring), 17(5), 1070–1076.CrossRef

49.

Anastasi. (1988). Psychological testing. New York.

50.

Dilorio, C. K. (2005). Measurement in health behavior methods for research and education. San Francisco: Wiley.

51.

Kazemi, H., Ramezani Tehrani, F., Minooee, S., Khalili, D., & Azizi, F. (2015). Women self-perception of excess hair growth, as a predictor of clinical hirsutism: A population-based study. Journal of Endocrinological Investigation, 38(8), 923–928.CrossRefPubMed

52.

Doward, L. C., Meads, D. M., & Thorsen, H. (2004). Requirements for quality of life instruments in clinical research. Value Health, 7(Suppl 1), S13–S16.CrossRefPubMed

53.

Jones, E. G., & Kay, M. (1992). Instrumentation in cross-cultural research. Nursing Research, 41(3), 186–188.CrossRefPubMed

54.

Jones, P. S., Lee, J. W., Phillips, L. R., Zhang, X. E., & Jaceldo, K. B. (2001). An adaptation of Brislin’s translation model for cross-cultural research. Nursing Research, 50(5), 300–304.CrossRefPubMed

55.

Jones, E. G., Mallinson, R. K., Phillips, L., & Kang, Y. (2006). Challenges in language, culture, and modality: Translating English measures into American sign language. Nursing Research, 55(2), 75–81.CrossRefPubMed

56.

Koprowski, C., Coates, R. J., & Bernstein, L. (2001). Ability of young women to recall past body size and age at menarche. Obesity Research, 9(8), 478–485.CrossRefPubMed

57.

Coffey, S., Bano, G., & Mason, H. D. (2006). Health-related quality of life in women with polycystic ovary syndrome: A comparison with the general population using the Polycystic Ovary Syndrome Questionnaire (PCOSQ) and the Short Form-36 (SF-36). Gynecological Endocrinology, 22(2), 80–86.CrossRefPubMed

Titel: Health-related quality of life questionnaire for polycystic ovary syndrome (PCOSQ-50): development and psychometric properties
Auteurs: Fatemeh Nasiri-Amiri
Fahimeh Ramezani Tehrani
Masoumeh Simbar
Ali Montazeri
Reza Ali Mohammadpour
Publicatiedatum: 01-07-2016
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 7/2016
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-016-1232-7

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Purpose

Methods

Results

Conclusion

Log in om toegang te krijgen

Andere artikelen Uitgave 7/2016

Response shift and disease activity in inflammatory bowel disease

Item bank development, calibration and validation for patient-reported outcomes in female urinary incontinence

Determinants of time trade-off valuations for EQ-5D-5L health states: data from the Canadian EQ-5D-5L valuation study

The association between social network factors and mental health at different life stages

Measuring nonspecific factors in treatment: item banks that assess the healthcare experience and attitudes from the patient’s perspective

Satisfaction with life in adults with Marfan syndrome (MFS): associations with health-related consequences of MFS, pain, fatigue, and demographic factors