Gepubliceerd in:

01-02-2013

Cerebral imaging with 7-Tesla MRI in patients with sickle cell disease: a pilot study

Auteurs: Veronica van der Land, Jaco J. Zwanenburg, Bart J. Biemond, Jeroen Hendrikse, Henk-Jan M. M. Mutsaerts, Marc Engelen, Aart J. Nederveen, Paul J. Nederkoorn, Charles B.L.M. Majoie, Peter R. Luijten, Karin Fijnvandraat

Gepubliceerd in: Tijdschrift voor Kindergeneeskunde | bijlage 1/2013

Extract

Silent cerebral infarction (SCI) is an important complication of sickle cell disease (SCD) and can lead to neurocognitive dysfunction. Typically, SCI’s are white matter lesions of unknown etiology. They are not associated with stenosis of large intracranial vessels. White matter lesions in other conditions (Alzheimer’s disease, hypertension) are considered an aspect of small vessel disease along with other lesions such as microbleeds and microinfarcts. We performed ultra high field MRI (7T) to study the manifestations of small vessel disease in patients with SCD. …

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Bohn Stafleu van Loghum

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