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24-02-2021 | Review

A closer look at quality of life in the hepatocellular carcinoma literature

Auteurs: Jenny L. Firkins, Robin Tarter, Martha Driessnack, Lissi Hansen

Gepubliceerd in: Quality of Life Research | Uitgave 6/2021

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Abstract

Purpose

Adults with hepatocellular carcinoma (HCC) have a high symptom burden. Their quality of life (QOL) has been shown to be significantly impacted by both the disease and its treatment, adding to the high symptom burden that these patients experience. The primary aims of this paper are as follows: (1) to identify how QOL is being defined in HCC literature and (2) to identify how QOL is being measured in the HCC literature using Ferrell’s model of QOL.

Methods

A systematic review was completed of relevant studies published after 2014, using PubMed, CINHAL, and PsycInfo. Relevant studies were reviewed by 2 reviewers using PRISMA guidelines.

Results

From a total of 1312 papers obtained in the initial database search, 30 met inclusion criteria and are included in this review. From the included articles, 10% included a definition of QOL and 3% addressed the spiritual domain of QOL. Majority of study participants were in the early stage of HCC, though the majority of adults with HCC are diagnosed in the advanced stage. Only 3% of included studies included greater than 22% population of advanced stage of HCC.

Conclusion

The results of this systematic review demonstrate the need for future research into QOL in the advanced stage of QOL. It also identified gap in the literature concerning the definition of QOL in HCC and the spiritual domain of QOL in HCC.
Literatuur
1.
go back to reference McGlynn, K. A., Petrick, J. L., & London, W. T. (2015). Global epidemiology of hepatocellular carcinoma: An emphasis on demographic and regional variability. Clinical Liver Disease, 19(2), 223–238.CrossRef McGlynn, K. A., Petrick, J. L., & London, W. T. (2015). Global epidemiology of hepatocellular carcinoma: An emphasis on demographic and regional variability. Clinical Liver Disease, 19(2), 223–238.CrossRef
2.
go back to reference Thomas, J. D., et al. (2011). Liver Cancer. In C. D. Blanke, C. Rödel, & M. S. Talamonti (Eds.), Gastrointestinal oncology: A practical guide (pp. 225–249). Berlin: Springer.CrossRef Thomas, J. D., et al. (2011). Liver Cancer. In C. D. Blanke, C. Rödel, & M. S. Talamonti (Eds.), Gastrointestinal oncology: A practical guide (pp. 225–249). Berlin: Springer.CrossRef
3.
go back to reference Bray, F., et al. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer Journal for Clinicians, 68(6), 394–424.CrossRef Bray, F., et al. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer Journal for Clinicians, 68(6), 394–424.CrossRef
4.
go back to reference Jemal, A., et al. (2017). Annual report to the nation on the status of cancer, 1975–2014, featuring survival. Journal of the National Cancer Institute, 109(9), djx030.PubMedCentralCrossRef Jemal, A., et al. (2017). Annual report to the nation on the status of cancer, 1975–2014, featuring survival. Journal of the National Cancer Institute, 109(9), djx030.PubMedCentralCrossRef
7.
go back to reference Mudumbi, S. K., et al. (2018). Palliative care and hospice interventions in decompensated cirrhosis and hepatocellular carcinoma: A rapid review of literature. Journal of Palliative Medicine, 21(8), 1177–1184.PubMedPubMedCentralCrossRef Mudumbi, S. K., et al. (2018). Palliative care and hospice interventions in decompensated cirrhosis and hepatocellular carcinoma: A rapid review of literature. Journal of Palliative Medicine, 21(8), 1177–1184.PubMedPubMedCentralCrossRef
8.
go back to reference Harris, R., et al. (2017). Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: A systematic review. The Lancet Gastroenterology & Hepatology, 2(4), 288–297.CrossRef Harris, R., et al. (2017). Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: A systematic review. The Lancet Gastroenterology & Hepatology, 2(4), 288–297.CrossRef
9.
go back to reference Fitzmorris, P., et al. (2015). Management of hepatocellular carcinoma. Journal of Cancer Research and Clinical Oncology, 141(5), 861–876.PubMedCrossRef Fitzmorris, P., et al. (2015). Management of hepatocellular carcinoma. Journal of Cancer Research and Clinical Oncology, 141(5), 861–876.PubMedCrossRef
10.
go back to reference Ferrell, B. R., & Hassey Dow, K. (1997). Quality of life among long-term cancer survivors. Oncology, 11(4), 565–568, 571; discussion 572, 575–576.PubMed Ferrell, B. R., & Hassey Dow, K. (1997). Quality of life among long-term cancer survivors. Oncology, 11(4), 565–568, 571; discussion 572, 575–576.PubMed
11.
go back to reference Felce, D., & Perry, J. (1995). Quality of life: Its definition and measurement. Research in Developmental Disabilities, 16(1), 51–74.PubMedCrossRef Felce, D., & Perry, J. (1995). Quality of life: Its definition and measurement. Research in Developmental Disabilities, 16(1), 51–74.PubMedCrossRef
12.
go back to reference Peplau, H. E. (1994). Quality of life: An interpersonal perspective. Nurse Science Quarterly, 7(1), 10–15.CrossRef Peplau, H. E. (1994). Quality of life: An interpersonal perspective. Nurse Science Quarterly, 7(1), 10–15.CrossRef
14.
go back to reference Costa, D. S., & King, M. T. (2013). Conceptual, classification or causal: Models of health status and health-related quality of life. Expert Review of Pharmacoeconomics & Outcomes Research, 13(5), 631–640.CrossRef Costa, D. S., & King, M. T. (2013). Conceptual, classification or causal: Models of health status and health-related quality of life. Expert Review of Pharmacoeconomics & Outcomes Research, 13(5), 631–640.CrossRef
15.
go back to reference Ware, J. E., Jr. (1984). Methodology in behavioral and psychosocial cancer research. Conceptualizing disease impact and treatment outcomes. Cancer, 53(10 Suppl), 2316–2326.CrossRef Ware, J. E., Jr. (1984). Methodology in behavioral and psychosocial cancer research. Conceptualizing disease impact and treatment outcomes. Cancer, 53(10 Suppl), 2316–2326.CrossRef
16.
go back to reference Patrick, D. L., & Bergner, M. (1990). Measurement of health status in the 1990s. Annual Review of Public Health, 11, 165–183.PubMedCrossRef Patrick, D. L., & Bergner, M. (1990). Measurement of health status in the 1990s. Annual Review of Public Health, 11, 165–183.PubMedCrossRef
17.
go back to reference Wilson, I. B., & Cleary, P. D. (1995). Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. Jama, 273(1), 59–65.PubMedCrossRef Wilson, I. B., & Cleary, P. D. (1995). Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes. Jama, 273(1), 59–65.PubMedCrossRef
18.
go back to reference Read, J. L., Quinn, R. J., & Hoefer, M. A. (1987). Measuring overall health: An evaluation of three important approaches. Journal of Chronic Diseases, 40(Suppl 1), 7s–26s.PubMedCrossRef Read, J. L., Quinn, R. J., & Hoefer, M. A. (1987). Measuring overall health: An evaluation of three important approaches. Journal of Chronic Diseases, 40(Suppl 1), 7s–26s.PubMedCrossRef
19.
go back to reference Ferrell, B. R. (1996). The quality of lives: 1,525 voices of cancer. Oncology Nursing Forum, 23(6), 909–916.PubMed Ferrell, B. R. (1996). The quality of lives: 1,525 voices of cancer. Oncology Nursing Forum, 23(6), 909–916.PubMed
20.
go back to reference Fan, S. Y., Eiser, C., & Ho, M. C. (2010). Health-related quality of life in patients with hepatocellular carcinoma: A systematic review. Clinical Gastroenterology and Hepatology, 8(7), 559-64.e1–10.PubMedCrossRef Fan, S. Y., Eiser, C., & Ho, M. C. (2010). Health-related quality of life in patients with hepatocellular carcinoma: A systematic review. Clinical Gastroenterology and Hepatology, 8(7), 559-64.e1–10.PubMedCrossRef
21.
go back to reference Gandhi, S., Khubchandani, S., & Iyer, R. (2014). Quality of life and hepatocellular carcinoma. Journal of Gastrointestinal Oncology, 5(4), 296–317.PubMedPubMedCentral Gandhi, S., Khubchandani, S., & Iyer, R. (2014). Quality of life and hepatocellular carcinoma. Journal of Gastrointestinal Oncology, 5(4), 296–317.PubMedPubMedCentral
22.
go back to reference Liu, J., Mittendorf, T., & von der Schulenburg, J. M. (2010). A structured review and guide through studies on health-related quality of life in kidney cancer, hepatocellular carcinoma, and leukemia. Cancer Investigation, 28(3), 312–322.PubMedCrossRef Liu, J., Mittendorf, T., & von der Schulenburg, J. M. (2010). A structured review and guide through studies on health-related quality of life in kidney cancer, hepatocellular carcinoma, and leukemia. Cancer Investigation, 28(3), 312–322.PubMedCrossRef
23.
go back to reference Ouzzani, M., et al. (2016). Rayyan-a web and mobile app for systematic reviews. Systematic Review, 5(1), 210.CrossRef Ouzzani, M., et al. (2016). Rayyan-a web and mobile app for systematic reviews. Systematic Review, 5(1), 210.CrossRef
24.
go back to reference Pugh, R. N., et al. (1973). Transection of the oesophagus for bleeding oesophageal varices. British Journal of Surgery, 60(8), 646–649.CrossRef Pugh, R. N., et al. (1973). Transection of the oesophagus for bleeding oesophageal varices. British Journal of Surgery, 60(8), 646–649.CrossRef
25.
go back to reference Bernard, M., et al. (2017). Relationship between spirituality, meaning in life, psychological distress, wish for hastened death, and their influence on quality of life in palliative care patients. Journal of Pain and Symptom Management, 54(4), 514–522.PubMedCrossRef Bernard, M., et al. (2017). Relationship between spirituality, meaning in life, psychological distress, wish for hastened death, and their influence on quality of life in palliative care patients. Journal of Pain and Symptom Management, 54(4), 514–522.PubMedCrossRef
26.
go back to reference Bovero, A., et al. (2016). Spirituality, quality of life, psychological adjustment in terminal cancer patients in hospice. European Journal of Cancer Care, 25(6), 961–969.PubMedCrossRef Bovero, A., et al. (2016). Spirituality, quality of life, psychological adjustment in terminal cancer patients in hospice. European Journal of Cancer Care, 25(6), 961–969.PubMedCrossRef
27.
go back to reference Wang, C. W., Chow, A. Y., & Chan, C. L. (2017). The effects of life review interventions on spiritual well-being, psychological distress, and quality of life in patients with terminal or advanced cancer: A systematic review and meta-analysis of randomized controlled trials. Palliative Medicine, 31(10), 883–894.PubMedCrossRef Wang, C. W., Chow, A. Y., & Chan, C. L. (2017). The effects of life review interventions on spiritual well-being, psychological distress, and quality of life in patients with terminal or advanced cancer: A systematic review and meta-analysis of randomized controlled trials. Palliative Medicine, 31(10), 883–894.PubMedCrossRef
28.
go back to reference Znaor, A., et al. (2018). The public health challenge of liver cancer in Mongolia. The Lancet Gastroenterology & Hepatology, 3(10), 660–662.CrossRef Znaor, A., et al. (2018). The public health challenge of liver cancer in Mongolia. The Lancet Gastroenterology & Hepatology, 3(10), 660–662.CrossRef
29.
go back to reference Lemoine, M., & Thursz, M. R. (2017). Battlefield against hepatitis B infection and HCC in Africa. Journal of Hepatology, 66(3), 645–654.PubMedCrossRef Lemoine, M., & Thursz, M. R. (2017). Battlefield against hepatitis B infection and HCC in Africa. Journal of Hepatology, 66(3), 645–654.PubMedCrossRef
30.
go back to reference Fateen, W., & Ryder, S. D. (2017). Screening for hepatocellular carcinoma: Patient selection and perspectives. Journal of Hepatocellular Carcinoma, 4, 71–79.PubMedPubMedCentralCrossRef Fateen, W., & Ryder, S. D. (2017). Screening for hepatocellular carcinoma: Patient selection and perspectives. Journal of Hepatocellular Carcinoma, 4, 71–79.PubMedPubMedCentralCrossRef
31.
go back to reference Scott, N. W., Fayers, P. M., Aaronson, N. K., Bottomley, A., de Graeff, A., Groenvold, M., et al. (2008). EORTC QLQ-C30 reference values. Brussels, Belgium: EORTC Quality of Life Group. Scott, N. W., Fayers, P. M., Aaronson, N. K., Bottomley, A., de Graeff, A., Groenvold, M., et al. (2008). EORTC QLQ-C30 reference values. Brussels, Belgium: EORTC Quality of Life Group.
32.
go back to reference Cella, D. F., et al. (1993). The functional assessment of cancer therapy scale: Development and validation of the general measure. Journal of Clinical Oncology, 11(3), 570–579.PubMedCrossRef Cella, D. F., et al. (1993). The functional assessment of cancer therapy scale: Development and validation of the general measure. Journal of Clinical Oncology, 11(3), 570–579.PubMedCrossRef
33.
go back to reference Phillips, R., et al. (2015). Summary scores captured changes in subjects’ QoL as measured by the multiple scales of the EORTC QLQ-C30. Journal of Clinical Epidemiology, 68(8), 895–902.PubMedCrossRef Phillips, R., et al. (2015). Summary scores captured changes in subjects’ QoL as measured by the multiple scales of the EORTC QLQ-C30. Journal of Clinical Epidemiology, 68(8), 895–902.PubMedCrossRef
34.
35.
go back to reference Bianchi, G., et al. (2003). Reduced quality of life of patients with hepatocellular carcinoma. Digestive and Liver Disease, 35(1), 46–54.PubMedCrossRef Bianchi, G., et al. (2003). Reduced quality of life of patients with hepatocellular carcinoma. Digestive and Liver Disease, 35(1), 46–54.PubMedCrossRef
36.
go back to reference Bonnetain, F., et al. (2008). Quality of life as a prognostic factor of overall survival in patients with advanced hepatocellular carcinoma: Results from two French clinical trials. Quality of Life Research, 17(6), 831–843.PubMedCrossRef Bonnetain, F., et al. (2008). Quality of life as a prognostic factor of overall survival in patients with advanced hepatocellular carcinoma: Results from two French clinical trials. Quality of Life Research, 17(6), 831–843.PubMedCrossRef
37.
go back to reference Chie, W. C., et al. (2017). Differences in health-related quality of life between European and Asian patients with hepatocellular carcinoma. Asia-Pacific Journal of Clinical Oncology, 13(5), e304–e311.PubMedCrossRef Chie, W. C., et al. (2017). Differences in health-related quality of life between European and Asian patients with hepatocellular carcinoma. Asia-Pacific Journal of Clinical Oncology, 13(5), e304–e311.PubMedCrossRef
38.
go back to reference Diouf, M., et al. (2013). The added value of quality of life (QoL) for prognosis of overall survival in patients with palliative hepatocellular carcinoma. Journal of Hepatology, 58(3), 509–521.PubMedCrossRef Diouf, M., et al. (2013). The added value of quality of life (QoL) for prognosis of overall survival in patients with palliative hepatocellular carcinoma. Journal of Hepatology, 58(3), 509–521.PubMedCrossRef
39.
go back to reference Fan, S. Y., et al. (2013). Health-related quality of life in patients with hepatocellular carcinoma: The mediation effects of illness perceptions and coping. Psychooncology, 22(6), 1353–1360.PubMedCrossRef Fan, S. Y., et al. (2013). Health-related quality of life in patients with hepatocellular carcinoma: The mediation effects of illness perceptions and coping. Psychooncology, 22(6), 1353–1360.PubMedCrossRef
40.
go back to reference Gill, J., et al. (2018). Insights into the hepatocellular carcinoma patient journey: Results of the first global quality of life survey. Future Oncology, 14(17), 1701–1710.PubMedCrossRef Gill, J., et al. (2018). Insights into the hepatocellular carcinoma patient journey: Results of the first global quality of life survey. Future Oncology, 14(17), 1701–1710.PubMedCrossRef
41.
go back to reference Gmur, A., et al. (2018). FACT-Hep increases the accuracy of survival prediction in HCC patients when added to ECOG Performance Status. Liver International, 38(8), 1468–1474.PubMedCrossRef Gmur, A., et al. (2018). FACT-Hep increases the accuracy of survival prediction in HCC patients when added to ECOG Performance Status. Liver International, 38(8), 1468–1474.PubMedCrossRef
42.
go back to reference Hsu, W. C., et al. (2012). Mini-nutritional assessment predicts functional status and quality of life of patients with hepatocellular carcinoma in Taiwan. Nutrition and Cancer, 64(4), 543–549.PubMedCrossRef Hsu, W. C., et al. (2012). Mini-nutritional assessment predicts functional status and quality of life of patients with hepatocellular carcinoma in Taiwan. Nutrition and Cancer, 64(4), 543–549.PubMedCrossRef
43.
go back to reference Jie, B., et al. (2016). Impact of disclosure of diagnosis and patient autonomy on quality of life and illness perceptions in Chinese patients with liver cancer. Psychooncology, 25(8), 927–932.PubMedCrossRef Jie, B., et al. (2016). Impact of disclosure of diagnosis and patient autonomy on quality of life and illness perceptions in Chinese patients with liver cancer. Psychooncology, 25(8), 927–932.PubMedCrossRef
44.
go back to reference Kim, G. A., et al. (2019). A prospective evaluation of the reliability and utility of quality of life measures in patients with hepatocellular carcinoma. American Journal of Clinical Oncology, 42(7), 555–563.PubMedCrossRef Kim, G. A., et al. (2019). A prospective evaluation of the reliability and utility of quality of life measures in patients with hepatocellular carcinoma. American Journal of Clinical Oncology, 42(7), 555–563.PubMedCrossRef
45.
go back to reference Kondo, Y., et al. (2007). Health-related quality of life of chronic liver disease patients with and without hepatocellular carcinoma. Journal of Gastroenterology & Hepatology, 22(2), 197–203.CrossRef Kondo, Y., et al. (2007). Health-related quality of life of chronic liver disease patients with and without hepatocellular carcinoma. Journal of Gastroenterology & Hepatology, 22(2), 197–203.CrossRef
46.
go back to reference Lam, E. T., et al. (2009). Health-related quality of life of Southern Chinese with chronic hepatitis B infection. Health and Quality of Life Outcomes, 7, 52.PubMedPubMedCentralCrossRef Lam, E. T., et al. (2009). Health-related quality of life of Southern Chinese with chronic hepatitis B infection. Health and Quality of Life Outcomes, 7, 52.PubMedPubMedCentralCrossRef
47.
48.
go back to reference Meier, A., et al. (2015). Role functioning is associated with survival in patients with hepatocellular carcinoma. Quality of Life Research, 24(7), 1669–1675.PubMedCrossRef Meier, A., et al. (2015). Role functioning is associated with survival in patients with hepatocellular carcinoma. Quality of Life Research, 24(7), 1669–1675.PubMedCrossRef
49.
go back to reference Mikoshiba, N., et al. (2013). Depressive symptoms after treatment in hepatocellular carcinoma survivors: Prevalence, determinants, and impact on health-related quality of life. Psychooncology, 22(10), 2347–2353.PubMedCrossRef Mikoshiba, N., et al. (2013). Depressive symptoms after treatment in hepatocellular carcinoma survivors: Prevalence, determinants, and impact on health-related quality of life. Psychooncology, 22(10), 2347–2353.PubMedCrossRef
50.
go back to reference Palmieri, V. O., et al. (2015). Psychopathological profile and health-related quality of life (HRQOL) in patients with hepatocellular carcinoma (HCC) and cirrhosis. Clinical and Experimental Medicine, 15(1), 65–72.PubMedCrossRef Palmieri, V. O., et al. (2015). Psychopathological profile and health-related quality of life (HRQOL) in patients with hepatocellular carcinoma (HCC) and cirrhosis. Clinical and Experimental Medicine, 15(1), 65–72.PubMedCrossRef
51.
go back to reference Qiao, C. X., et al. (2012). Health-related quality of life evaluated by tumor node metastasis staging system in patients with hepatocellular carcinoma. World Journal of Gastroenterology, 18(21), 2689–2694.PubMedPubMedCentralCrossRef Qiao, C. X., et al. (2012). Health-related quality of life evaluated by tumor node metastasis staging system in patients with hepatocellular carcinoma. World Journal of Gastroenterology, 18(21), 2689–2694.PubMedPubMedCentralCrossRef
52.
go back to reference Ryu, E., et al. (2010). Symptom clusters and quality of life in Korean patients with hepatocellular carcinoma. Cancer Nursing, 33(1), 3–10.PubMedCrossRef Ryu, E., et al. (2010). Symptom clusters and quality of life in Korean patients with hepatocellular carcinoma. Cancer Nursing, 33(1), 3–10.PubMedCrossRef
53.
go back to reference Shiraki, M., et al. (2013). Nutritional status and quality of life in current patients with liver cirrhosis as assessed in 2007–2011. Hepatology Research, 43(2), 106–112.PubMedCrossRef Shiraki, M., et al. (2013). Nutritional status and quality of life in current patients with liver cirrhosis as assessed in 2007–2011. Hepatology Research, 43(2), 106–112.PubMedCrossRef
54.
go back to reference Steel, J. L., et al. (2006). Clinically meaningful changes in health-related quality of life in patients diagnosed with hepatobiliary carcinoma. Annals of Oncology, 17(2), 304–312.PubMedCrossRef Steel, J. L., et al. (2006). Clinically meaningful changes in health-related quality of life in patients diagnosed with hepatobiliary carcinoma. Annals of Oncology, 17(2), 304–312.PubMedCrossRef
55.
go back to reference Steel, J. L., et al. (2007). Health-related quality of life: Hepatocellular carcinoma, chronic liver disease, and the general population. Quality of Life Research Quality of Life Research, 16(2), 203–215.PubMedCrossRef Steel, J. L., et al. (2007). Health-related quality of life: Hepatocellular carcinoma, chronic liver disease, and the general population. Quality of Life Research Quality of Life Research, 16(2), 203–215.PubMedCrossRef
56.
go back to reference Steel, J., et al. (2005). Sexual functioning in patients with hepatocellular carcinoma. Cancer, 104(10), 2234–2243.PubMedCrossRef Steel, J., et al. (2005). Sexual functioning in patients with hepatocellular carcinoma. Cancer, 104(10), 2234–2243.PubMedCrossRef
57.
go back to reference Steel, J. L., Geller, D. A., & Carr, B. I. (2005). Proxy ratings of health related quality of life in patients with hepatocellular carcinoma. Quality of Life Research, 14(4), 1025–1033.PubMedCrossRef Steel, J. L., Geller, D. A., & Carr, B. I. (2005). Proxy ratings of health related quality of life in patients with hepatocellular carcinoma. Quality of Life Research, 14(4), 1025–1033.PubMedCrossRef
58.
go back to reference Sternby Eilard, M., et al. (2018). Quality of life as a prognostic factor for survival in hepatocellular carcinoma. Liver International, 38(5), 885–894.PubMedCrossRef Sternby Eilard, M., et al. (2018). Quality of life as a prognostic factor for survival in hepatocellular carcinoma. Liver International, 38(5), 885–894.PubMedCrossRef
59.
go back to reference Sun, V., et al. (2008). Symptom concerns and quality of life in hepatobiliary cancers. Oncology Nursing Forum, 35(3), E45-52.PubMedCrossRef Sun, V., et al. (2008). Symptom concerns and quality of life in hepatobiliary cancers. Oncology Nursing Forum, 35(3), E45-52.PubMedCrossRef
60.
go back to reference Ueno, S., et al. (2002). Quality of life after hepatectomy in patients with hepatocellular carcinoma: Implication of change in hepatic protein synthesis. Hepato-Gastroenterology, 49(44), 492–496.PubMed Ueno, S., et al. (2002). Quality of life after hepatectomy in patients with hepatocellular carcinoma: Implication of change in hepatic protein synthesis. Hepato-Gastroenterology, 49(44), 492–496.PubMed
61.
go back to reference Wong, W. S., & Fielding, R. (2008). The association between patient satisfaction and quality of life in Chinese lung and liver cancer patients. Medical Care, 46(3), 293–302.PubMedCrossRef Wong, W. S., & Fielding, R. (2008). The association between patient satisfaction and quality of life in Chinese lung and liver cancer patients. Medical Care, 46(3), 293–302.PubMedCrossRef
62.
go back to reference Yeo, W., et al. (2006). Quality of life is predictive of survival in patients with unresectable hepatocellular carcinoma. Annals of Oncology, 17(7), 1083–1089.PubMedCrossRef Yeo, W., et al. (2006). Quality of life is predictive of survival in patients with unresectable hepatocellular carcinoma. Annals of Oncology, 17(7), 1083–1089.PubMedCrossRef
63.
go back to reference Zheng, W., et al. (2013). Survival and health-related quality of life in patients with spinal metastases originated from primary hepatocellular carcinoma. Journal of Evidence-Based Integrative Medicine, 6(2), 81–89.CrossRef Zheng, W., et al. (2013). Survival and health-related quality of life in patients with spinal metastases originated from primary hepatocellular carcinoma. Journal of Evidence-Based Integrative Medicine, 6(2), 81–89.CrossRef
Metagegevens
Titel
A closer look at quality of life in the hepatocellular carcinoma literature
Auteurs
Jenny L. Firkins
Robin Tarter
Martha Driessnack
Lissi Hansen
Publicatiedatum
24-02-2021
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 6/2021
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-021-02789-2

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