Endoscopy 2004; 36(9): 770-775
DOI: 10.1055/s-2004-825816
DDW Report 2004
© Georg Thieme Verlag Stuttgart · New York

DDW Report 2004 New Orleans: Reflux Disease and Barrett’s Esophagus

T.  Rösch1
  • 1 Interdisciplinary Endoscopy Unit, Dept. of Gastroenterology, Charité University, Rudolf Virchow Campus, Berlin, Germany
Further Information

Publication History

Publication Date:
24 August 2004 (online)

Introduction

Gastroesophageal reflux disease (GERD) and Barrett’s esophagus (BE) are still major topics in the field of clinical research. More data are accumulating concerning the endoscopic diagnosis of subtle abnormalities, to allow better classification of patients into those who are endoscopy-positive or endoscopy-negative (nonerosive reflux disease). The situation with regard to endoscopic antireflux techniques has not become much clearer, although evidence appears to be gathering to show that they are not objectively effective. In Barrett’s esophagus (BE), many abstracts dealt with diagnostic techniques, as well as resection and ablation methods, without there being any substantial breakthroughs. As with the other Digestive Disease Week reports, only the most relevant studies are reported in detail here. The remaining abstracts are summarized in the tables.

References

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  • 24 Fockens P, Bruno M J, Gabbrielli A. et al . Endoscopic augmentation of the lower esophageal sphincter for the treatment of gastroesophageal reflux disease: multicenter study of the Gatekeeper™ Reflux Repair System.  Endoscopy. 2004;  [in press]
  • 25 Edmundowicz S A, Perrone J M, Siegel L C. et al . Randomized controlled evaluation of a novel endoscopic stapling system in an animal model for GERD [abstract].  Gastrointest Endosc. 2004;  59 AB148
  • 26 Vinciane M. A prospective endoscopic study of cardial intestinal metaplasia [abstract].  Gastrointest Endosc. 2004;  59 AB258
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  • 28 Dulai G, Jensen D M, Saad M. et al . Simultaneous screening for Barrett’s and colorectal cancer [abstract].  Gastrointest Endosc. 2004;  59 AB259
  • 29 DeVault K R, Ward E M, Wolfsen H C. et al . Barrett’s esophagus (BE) is common in older patients undergoing screening colonoscopy regardless of gastroesophageal reflux (GER) symptoms [abstract].  Gastrointest Endosc. 2004;  59 AB111
  • 30 Siersema P D, Yu S, Sahbaie P. et al . Colorectal neoplasia in veterans is associated with Barrett’s esophagus but not with use of proton-pump inhibitors (PPIs) or aspirin/NSAIDs [abstract].  Gastrointest Endosc. 2004;  59 AB259
  • 31 Wong S N, Sollano J D, Jr, Chan M M. et al . Unrecognized Barrett’s esophagus in patients with erosive esophagitis unveiled by methylene blue chromoendoscopy [abstract].  Gastrointest Endosc. 2004;  59 AB262
  • 32 Kim H K, Park S H, Kim J K. et al . Acetic acid chromoendoscopy improved detection of islands of Barrett’s epithelium in GERD patients [abstract].  Gastrointest Endosc. 2004;  59 AB264
  • 33 Hanna S, Weston A, Mathur S. et al . The detection of Barrett’s esophagus after endoscopic healing of erosive esophagitis [abstract].  Gastrointest Endosc. 2004;  59 AB261
  • 34 Ferguson D D, DeVault K R, Wolfsen H C. Should we biopsy an irregular Z-line? The yield of biopsy to diagnose short-segment Barrett’s esophagus [abstract].  Gastrointest Endosc. 2004;  59 AB264
  • 35 Sharpe L M, Li X, Cowan D. et al . Temporal change in Barrett’s esophagus segment length (BESL) during prospective surveillance [abstract].  Gastrointest Endosc. 2004;  59 AB262
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  • 37 Kara M, Ennahachi M, Fockens P. et al . Narrow-band imaging (NBI) in Barrett’s esophagus (BE): what features are relevant for the detection of high-grade dysplasia (HGD) and early cancer (EC)? [abstract].  Gastroenterology. 2004;  126 A50
  • 38 Sharma P, Mathur S, Dixon A. et al . Narrow-band imaging endoscopy for the detection of dysplastic and nondysplastic Barrett’s esophagus [abstract].  Gastrointest Endosc. 2004;  59 AB263
  • 39 Miros M, Cohn D, Walker N. Acetic acid magnification chromoendoscopy detects all focal high-grade dysplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2004;  59 AB264
  • 40 Lovat L B, Johnson K, Novelli M R. et al . Optical biopsy using elastic scattering spectroscopy can detect high-grade dysplasia and cancer in Barrett’s esophagus [abstract].  Gastroenterology. 2004;  126 A22
  • 41 Rabago L R, Delgado M, de Vicente C. et al . Intraoperative ERCP for the management of choledocholithiasis: a comparative study [abstract].  Gastrointest Endosc. 2004;  59 AB199
  • 42 Evans J A, Poneros J M, Bouma B R. et al . Application of a histopathologic scoring system to optical coherence tomography (OCT) images to identify high-grade dysplasia in Barrett’s esophagus [abstract].  Gastroenterology. 2004;  126 A51
  • 43 Kara M, DaCosta R, Streutker C. et al . Characterization of tissue autofluorescence (AF) in non-dysplastic (NDBE) and dysplastic Barrett’s esophagus (BE) by confocal fluorescence microscopy [abstract].  Gastroenterology. 2004;  126 A50-51
  • 44 Gossner L, May A, Stolte M. et al . High-resolution chromoendoscopy with acetic acid for the detection of intestinal metaplasia and early neoplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2004;  59 AB261
  • 45 Lightdale C, Larghi A, Rotterdam H. et al . Endoscopic ultrasonography (EUS) and endoscopic mucosal resection (EMR) for staging and treatment of high-grade dysplasia (HGD) and early adenocarcinoma (EAC) in Barrett’s esophagus (BE) [abstract].  Gastrointest Endosc. 2004;  59 AB90
  • 46 Gatenby P AC, Ramus J R, Caygill C PJ. et al . Incidence of adenocarcinoma in short- and long-segment columnar-lined esophagus [abstract].  Gastroenterology. 2004;  126 A308
  • 47 Von Rahden B HA, Stein H J, Feith M. et al . Experiences with endoscopic surveillance of patients with Barrett’s esophagus in a single German center [abstract].  Gastroenterology. 2004;  126 A795
  • 48 Misra N, Roberts L, Hardwick R H. Is improved accuracy of reporting an explanation for the increasing incidence of junctional adenocarcinoma? [abstract].  Gastroenterology. 2004;  126 A308
  • 49 Lewis J, Lutzke L, Smyrk T. et al . The limitations of endoscopic mucosal resection in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2004;  59 AB101
  • 50 Conio M, Repici A, Cestari R. et al . Endoscopic mucosal resection for high-grade dysplasia and intramucosal carcinoma occurring in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2004;  59 AB253
  • 51 Vieth M, Ell C, Gossner L. et al . Histologic analysis of endoscopic resection specimens from patients with Barrett’s esophagus and early neoplasia.  Endoscopy. 2004;  36 690-695
  • 52 Saito Y, Matsuda T, Saito D. et al . Does endoscopic resection increase the risk of lymph-node metastases? [abstract].  Gastrointest Endosc. 2004;  59 AB274
  • 53 Seewald S, Groth S, Brand B. et al . Circumferential EMT: future endoscopic management of HGIN and IMC in Barrett’s esophagus? Preliminary results of an ongoing study [abstract].  Gastrointest Endosc. 2004;  59 AB101
  • 54 Urayama S, Umphress J L. Wide endoscopic mucosal resection in esophagus using modified needle-knife: porcine model experiment [abstract].  Gastrointest Endosc. 2004;  59 AB258
  • 55 Dye C, Kinney T, Chi K. et al . Holmium laser-assisted mucosectomy (HLAM) [abstract].  Gastrointest Endosc. 2004;  59 AB90
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  • 57 Raju G S, Ahmed I, Xiao S Y. et al . Graded esophageal mucosal ablation with cryotherapy and protective effects of submucosal saline [abstract].  Gastrointest Endosc. 2004;  59 AB150
  • 58 Sharma V K, Fleischer D E, Wang K K. et al . A randomized multicenter trial of radiofrequency (RF) ablation of specialized intestinal metaplasia (SIM) of the esophagus using a balloon-based bipolar electrode array: preliminary results [abstract].  Gastrointest Endosc. 2004;  59 AB113
  • 59 Kelty C J, Ackroyd R, Brown N J. et al . Endoscopic ablation of Barrett’s esophagus: a randomized trial of photodynamic therapy (PTD) versus argon plasma coagulation (APC) [abstract].  Gastrointest Endosc. 2004;  59 AB250
  • 60 Forcione D G, Hasan T, Ortel B J. et al . Optimization of aminolevulinic acid-based photodynamic therapy of Barrett’s esophagus with high-grade dysplasia [abstract].  Gastrointest Endosc. 2004;  59 AB251
  • 61 Selvasekar C R, Novelli M R, Thorpe S. et al . Interim results of a randomized controlled trial (RCT) comparing green and red laser photodynamic therapy using low-dose ALA for high-grade dysplasia in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2004;  59 AB252
  • 62 Rahmani E Y, Nehme O, Arney K. et al . Successful eradication of Barrett’s mucosa with argon coagulation and acid suppression: mid-term results [abstract].  Gastrointest Endosc. 2004;  59 AB250
  • 63 Rahmani E Y, Turpin C, Arney K. Photodynamic therapy for dysplastic Barrett’s esophagus and early esophageal adenocarcinoma should be first-line therapy [abstract].  Gastrointest Endosc. 2004;  59 AB250
  • 64 Wolfsen H C, Hemminger L L. Photodynamic therapy for dysplastic Barrett’s esophagus and mucosal adenocarcinoma [abstract].  Gastrointest Endosc. 2004;  59 AB251
  • 65 Wang K K, Song L MWK, Buttar N. et al . Barrett’s esophagus after photodynamic therapy: risk of cancer development during long-term follow-up [abstract].  Gastroenterology. 2004;  126 A50
  • 66 Peters F, Kara M, Rosmolen W. et al . Endoscopic resection combined with photodynamic therapy for high-grade dysplasia and early cancer in Barrett’s esophagus [abstract].  Gastrointest Endosc. 2004;  59 AB251
  • 67 Haringsma J, Siersema P D, Kuipers E J. Endoscopic ablation of Barrett’s neoplasia: Rotterdam results [abstract].  Gastrointest Endosc. 2004;  59 AB252
  • 68 Ganz R A, Utley D S, Stern R. et al . Complete ablation of porcine esophageal epithelium using a balloon-based bipolar electrode [abstract].  Gastrointest Endosc. 2004;  59 AB250
  • 69 Ganz R A, Batts K. Pilot human study of a balloon-based bipolar electrode for ablation of esophageal epithelium: results in subjects prior to planned esophagectomy [abstract].  Gastrointest Endosc. 2004;  59 AB252

T. Rösch

Charité · Universitätsmedizin Berlin · Campus Virchow Klinikum · Medizinische Klinik m.S. Hepatologie und Gastroenterologie · Zentrale Interdisciplinäre Endoskopie

Augustenburger Platz 1 · 13535 Berlin · Germany

Fax: +49-30-450-553902

Email: thomas.roesch@charite.de

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